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Search Result

Search Results for " integrin "

Targets

Integrin Integrin

154

Compounds

9

Natural Products

215

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP1484L α2β1 Integrin Ligand Peptide acetate α2β1 Integrin Ligand Peptide acetate (134580-64-6) Integrin
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor. α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the...
T13473 αvβ1 integrin-IN-1 Integrin
αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.
T36291 Integrin modulator 1
Integrin modulator 1 is a potent and selective α4β1 integrin agonist, with an IC50 of 9.8 nM for RGD-binding α4β1. Integrin modulator 1 increases cell adhesion mediated by α4β1 integrin, with an EC50 of 12.9 nM[1]. Integ...
T40361 Integrin Binding Peptide
Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.
T40243 αvβ5 integrin-IN-1
αvβ5 integrin-IN-1, a potent and selective αvβ5 integrin inhibitor, exhibits a high inhibitory potency with a pIC50 value of 8.2.
T15584 Integrin Antagonists 27 Others
Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.
T11663 Integrin-IN-2 Others
Integrin-IN-2 is an orally bioavailable pan αv integrin inhibitor.Integrin-IN-2 can increases the αvβ6, αvβ3, αvβ5 and αvβ8 binding affinities with pIC50 values of 7.8, 8.4, 8.4 and 7.4, respectively.
TP1484 α2β1 Integrin Ligand Peptide
The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen recep...
T13473L αvβ1 integrin-IN-1 TFA (1689540-62-2 free base) αvβ1 integrin-IN-1 TFA Integrin
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).
TP1374 α2β1 Integrin Ligand Peptide TFA
α2β1 Integrin Ligand Peptide TFA interacts with the integrin receptor on the cell membrane and enters the cell to mediate extracellular signaling.It is a potential antagonist of the collagen receptor.
T79918 α7β1 integrin modulator-1 Integrin
α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].
T79140 αvβ6 integrin inhibitor 2 Integrin
αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.
T82063 Integrin signaling inhibitor, mP13
Integrin Signaling Inhibitor mP13 is a compound that impedes both inside-out and outside-in integrin-mediated signaling processes, such as fibrinogen binding, platelet adhesion, and clot retraction [1].
T79792 αvβ1 integrin-IN-2 Integrin
αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively. Additionally, this compound inhibits a range of other integrins, with IC50 valu...
T63868 α5β1 integrin agonist-1
α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.
T12177 Natalizumab Integrin
Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.
T73625 αvβ1 integrin-IN-1 TFA
αvβ1 Integrin-IN-1 TFA (Compound C8) is a potent, selective inhibitor of αvβ1 integrin, demonstrating an IC 50 value of 0.63 nM. It exhibits antifibrotic effects [1].
T16695 Pyrintegrin Integrin
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...
T6812L Cyclo(-RGDfK) TFA Integrin
Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).
TP1330 Cyclo(RADfK) Integrin
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.Cyclo(RADfK) is a negative control for the cyclo (-RGDfK-), the RGD peptide. RGD...
T6812 Cyclo(-RGDfK) Cyclo (-RGDfK) Integrin
Cyclo(-RGDfK) (Cyclo (-RGDfK)) is an effective and specific αvβ3 integrin inhibitor.
T8523 ILK-IN-3 Integrin
ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.
T7261 Grp94 Inhibitor-1 GPR , HSP
Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).
T13147 ICAM-1-IN-1 Integrin
ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.
TP1204 IRGD peptide c(CRGDKGPDC) Integrin
iRGD peptide (c(CRGDKGPDC)) is a 9-amino acid cyclic peptide (sequence: CRGDKGPDC) and a molecular mimicry agent that was originally identified in an in vivo screening of phage display libraries in tumor-bearing mice.
T4259 GLPG0187 Integrin
GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).
TQ0250 CWHM-12 Integrin
CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).
T21868 BIO-1211 Integrin
BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).
T6813 Cyclo(RGDyK) trifluoroacetate Cyclo(RGDyK) Integrin
Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
T21781 A-286982 Integrin
A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1.
TP1474 LXW7 Integrin
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 is a disulfide cyclic octa-pepti...
T5488 ILK-IN-2 OSU-T315 Integrin
ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.
T2254 A-205804 Integrin
A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.
T12783 RWJ 50271 Integrin
RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells).
T2494 Cilengitide EMD 121974 Integrin , Autophagy
Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.
T3638 Leukadherin-1 Integrin , Complement System
Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration; reduces inflammation.
T30751 Carotegrast methyl AJM300 Integrin
Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.
T4400 DIM-C-pPhOH CDIM8 Apoptosis , Others
DIM-C-pPhOH (CDIM8) is a nur77 (NR4A1) antagonist,inhibits TGF-β induced cell migration of breast cancer cell lines,promotes ROS/endoplasmic reticulum stress and proapoptotic pathways in pancreatic cancer cell lines,mimi...
T5310 TR-14035 MDK-1191 Integrin
TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).
T4435 E7820 ER68203-00 Integrin
E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
T10397 ATN-161 trifluoroacetate salt ATN-161 TFA salt Integrin
ATN-161 trifluoroacetate salt (ATN-161 TFA salt) is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases and improves survival in a murine model.
T6966 RGD RGD (Arg-Gly-Asp) Peptides,Arg-Gly-Asp,RGD Peptides Integrin
RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
T5485 OSU-T315 OSU-T315 (1,5-regioisomer),ILK-IN-2 Apoptosis , Integrin , Autophagy
OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.
T6182 Tirofiban L700462,Aggrastat,MK383 Integrin
Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
T3977 Lifitegrast SHP-606,SAR 1118 Integrin
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
T6657 SB273005 Integrin
SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.
T6806 Cilengitide TFA Integrin , Autophagy
Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.
T1950 PND-1186 PND1186,PND 1186,VS-4718,SR-2516 Apoptosis , FAK
PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).
T2537 Tirofiban hydrochloride monohydrate Tirofiban Hydrochloride,MK-383 Hydrochloride ATPase , Integrin
Tirofiban hydrochloride monohydrate (MK-383 Hydrochloride) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist.
T7570 RGD peptide (GRGDNP) RGD peptide GRGDNP(2TFA),RGD peptide GRGDNP Apoptosis , Integrin
RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.

Compounds

α2β1 Integrin Ligand Peptide acetate
TP1484L
Synonym: α2β1 Integrin Ligand Peptide acetate (134580-64-6)
Target: Integrin
αvβ1 integrin-IN-1
T13473
Synonym:
Target: Integrin
Integrin modulator 1
T36291
Synonym:
Target:
Integrin Binding Peptide
T40361
Synonym:
Target:
αvβ5 integrin-IN-1
T40243
Synonym:
Target:
Integrin Antagonists 27
T15584
Synonym:
Target: Others
Integrin-IN-2
T11663
Synonym:
Target: Others
α2β1 Integrin Ligand Peptide
TP1484
Synonym:
Target:
αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
T13473L
Synonym: αvβ1 integrin-IN-1 TFA
Target: Integrin
α2β1 Integrin Ligand Peptide TFA
TP1374
Synonym:
Target:
α7β1 integrin modulator-1
T79918
Synonym:
Target: Integrin
αvβ6 integrin inhibitor 2
T79140
Synonym:
Target: Integrin
Integrin signaling inhibitor, mP13
T82063
Synonym:
Target:
αvβ1 integrin-IN-2
T79792
Synonym:
Target: Integrin
α5β1 integrin agonist-1
T63868
Synonym:
Target:
Natalizumab
T12177
Synonym:
Target: Integrin
αvβ1 integrin-IN-1 TFA
T73625
Synonym:
Target:
Pyrintegrin
T16695
Synonym:
Target: Integrin
Cyclo(-RGDfK) TFA
T6812L
Synonym:
Target: Integrin
Cyclo(RADfK)
TP1330
Synonym:
Target: Integrin
Cyclo(-RGDfK)
T6812
Synonym: Cyclo (-RGDfK)
Target: Integrin
ILK-IN-3
T8523
Synonym:
Target: Integrin
Grp94 Inhibitor-1
T7261
Synonym:
Target: GPR, HSP
ICAM-1-IN-1
T13147
Synonym:
Target: Integrin
iRGD peptide
TP1204
Synonym: c(CRGDKGPDC)
Target: Integrin
GLPG0187
T4259
Synonym:
Target: Integrin
CWHM-12
TQ0250
Synonym:
Target: Integrin
BIO-1211
T21868
Synonym:
Target: Integrin
Cyclo(RGDyK) trifluoroacetate
T6813
Synonym: Cyclo(RGDyK)
Target: Integrin
A-286982
T21781
Synonym:
Target: Integrin
LXW7
TP1474
Synonym:
Target: Integrin
ILK-IN-2
T5488
Synonym: OSU-T315
Target: Integrin
A-205804
T2254
Synonym:
Target: Integrin
RWJ 50271
T12783
Synonym:
Target: Integrin
Cilengitide
T2494
Synonym: EMD 121974
Target: Integrin, Autophagy
Leukadherin-1
T3638
Synonym:
Target: Integrin, Complement System
Carotegrast methyl
T30751
Synonym: AJM300
Target: Integrin
DIM-C-pPhOH
T4400
Synonym: CDIM8
Target: Apoptosis, Others
TR-14035
T5310
Synonym: MDK-1191
Target: Integrin
E7820
T4435
Synonym: ER68203-00
Target: Integrin
ATN-161 trifluoroacetate salt
T10397
Synonym: ATN-161 TFA salt
Target: Integrin
RGD
T6966
Synonym: RGD (Arg-Gly-Asp) Peptides,Arg-Gly-Asp,RGD Peptides
Target: Integrin
OSU-T315
T5485
Synonym: OSU-T315 (1,5-regioisomer),ILK-IN-2
Target: Apoptosis, Integrin, Autophagy
Tirofiban
T6182
Synonym: L700462,Aggrastat,MK383
Target: Integrin
Lifitegrast
T3977
Synonym: SHP-606,SAR 1118
Target: Integrin
SB273005
T6657
Synonym:
Target: Integrin
Cilengitide TFA
T6806
Synonym:
Target: Integrin, Autophagy
PND-1186
T1950
Synonym: PND1186,PND 1186,VS-4718,SR-2516
Target: Apoptosis, FAK
Tirofiban hydrochloride monohydrate
T2537
Synonym: Tirofiban Hydrochloride,MK-383 Hydrochloride
Target: ATPase, Integrin
RGD peptide (GRGDNP)
T7570
Synonym: RGD peptide GRGDNP(2TFA),RGD peptide GRGDNP
Target: Apoptosis, Integrin
1 2 3 4
Cat No. Product Name Synonyms Targets
T3862 Irigenin NF-κB , Integrin
Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha...
T3404 Cucurbitacin B Cuc B,DATISCACIN,Amarine Apoptosis , PTEN , Integrin , Endogenous Metabolite , HIF , STAT , Autophagy
Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inh...
T36715 Tetrac Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid Apoptosis , EGFR
Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking EGFR-mediated cell signaling in colorectal cancer cells.Tetrac...
T3834 8-Epideoxyloganic acid ROS , Immunology/Inflammation related
8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibl...
T5S0055 Chelidonine Helidonine,Khelidonin,Stylophorin Apoptosis , Others , Influenza Virus
1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ...
T4S0498 Glaucocalyxin A Wangzaozin B,Leukamenin F Apoptosis , Akt , Caspase , PI3K
1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...
TN5447 Apigenin 7-O-methylglucuronide Apigenin-7-O-β-D-glucuronide methyl ester
Apigenin 7-O-methylglucuronide did not affect GAG level or secretion, may potentially be used in osteogenesis imperfecta (OI) type I pharmacotherapy in patients with normal GAG content. Apigenin 7-O-methylglucuronide whi...
T40960 Fibronectin Integrin
Fibronectin is a macromolecular glycoprotein found in blood, connective tissue, and cell surfaces that serves as a biomarker for tissue damage.Fibronectin is recognized by the integrin family of surface receptors.Fibrone...
T36295 Echistatin TFA
Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorpti...

Natural Products

Irigenin
T3862
Synonym:
Target: NF-κB, Integrin
Cucurbitacin B
T3404
Synonym: Cuc B,DATISCACIN,Amarine
Target: Apoptosis, PTEN, Integrin, Endogenous Metabolite, HIF, STAT, Autophagy
Tetrac
T36715
Synonym: Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid
Target: Apoptosis, EGFR
8-Epideoxyloganic acid
T3834
Synonym:
Target: ROS, Immunology/Inflammation related
Chelidonine
T5S0055
Synonym: Helidonine,Khelidonin,Stylophorin
Target: Apoptosis, Others, Influenza Virus
Glaucocalyxin A
T4S0498
Synonym: Wangzaozin B,Leukamenin F
Target: Apoptosis, Akt, Caspase, PI3K
Apigenin 7-O-methylglucuronide
TN5447
Synonym: Apigenin-7-O-β-D-glucuronide methyl ester
Target:
Fibronectin
T40960
Synonym:
Target: Integrin
Echistatin TFA
T36295
Synonym:
Target:

Recombinant Proteins

Species：
Human (118)
Mouse (50)
Rat (13)
Cynomolgus (7)
Bovine (3)
Chicken (3)
Bothrops atrox (2)
Canine (2)
RV-A (2)
Rabbit (2)
Expression System：
HEK293 (124)
E. coli (43)
Human Cells (27)
Yeast (10)
Baculovirus-Insect Cells (8)
Baculovirus (2)
in vitro E. coli expression system (1)
Tag：
His (56)
hFc (23)
N-terminal 6xHis-tagged (17)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (15)
C-6His (12)
C-His (11)
Tag Free (11)
Flag,His (7)
C-Fc (6)
N-terminal 6xHis-SUMO-tagged (6)
Cat No. Product Name Species Expression System
TMPY-04643 Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His) Mouse HEK293
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-05716 Integrin alpha V beta 3 Protein, Human, Recombinant (His) Human HEK293
Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor.
TMPY-05717 Integrin alpha V beta 8 Protein, Human, Recombinant (His) Human HEK293
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto...
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-02159 Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His) Human HEK293
TMPY-02160 Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His) Human HEK293
TMPY-04881 Integrin alpha 6 beta 4 Protein, Human, Recombinant (Flag & His) Human HEK293
TMPY-05762 Integrin alpha X beta 2 Protein, Human, Recombinant (His) Human HEK293
TMPY-02158 Integrin alpha 6 beta 1 Protein, Human, Recombinant (Flag & His) Human HEK293
TMPY-02161 Integrin alpha X beta 2 Protein, Human, Recombinant (Flag & His) Human HEK293
TMPY-00476 ITGB1 Protein, Human, Recombinant (His) Human HEK293
ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involv...
TMPJ-00211 CD47 Protein, Human, Recombinant (His) Human Human Cells
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an...
TMPK-00839 ITGB6 Protein, Human, Recombinant (His) Human HEK293
ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide ...
TMPK-01247 ITGB6 Protein, Mouse, Recombinant (His) Mouse HEK293
ITGB6 is known to be one of the major receptor components involved in host tropism of foot-and-mouth disease (FMD) virus in cattle. A competitive PCR technique called ARMS PCR was adapted to identify a single-nucleotide ...
TMPJ-00810 ITGA5 Protein, Human, Recombinant (His) Human Human Cells
Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In cas...
TMPY-02289 CIB2 Protein, Human, Recombinant (His) Human E. coli
Calcium and integrin-binding protein 2 (CIB2) belongs to a protein family with four known members, CIB1 through CIB4, which are characterized by multiple calcium-binding EF-hand domains. Sensorineural hearing loss is gen...
TMPJ-00786 ITGB1 Protein, Human, Recombinant (aa 21-728, His) Human Human Cells
Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue ...
TMPY-02198 ILKAP Protein, Human, Recombinant (His) Human HEK293
Integrin-linked kinase-associated serine/threonine phosphatase 2C, also known as ILKAP, is a cytoplasm protein that belongs to the PP2C family. ILKAP contains one PP2C-like domain. ILKAP is widely expressed. Highest leve...
TMPJ-00614 CD47 Protein, Rhesus macaque, Recombinant (His & Flag) Rhesus Macaque Human Cells
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD)...
TMPJ-00212 CD47 Protein, Human, Recombinant (mFc) Human Human Cells
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an...
TMPJ-00613 CD47 Protein, Rhesus macaque, Recombinant (hFc) Rhesus macaque Human Cells
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an...
TMPJ-00445 IBSP Protein, Mouse, Recombinant (His) Mouse Human Cells
Bone sialoprotein 2(IBSP) is a monomeric non‑collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesize...
TMPJ-00208 CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human Human Cells
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an...
TMPJ-00209 CD47 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, an...
TMPJ-00242 PARVA Protein, Human, Recombinant (His) Human E. coli
Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with i...
TMPH-00213 Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc) Bothrops atrox E. coli
Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor a...
TMPH-02569 WISP2/CCN5 Protein, Mouse, Recombinant (His) Mouse Yeast
May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
TMPY-00970 CD31/PECAM-1 Protein, Human, Recombinant (His) Human HEK293
The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transm...
TMPY-03630 MZB1/PERP1 Protein, Human, Recombinant (His) Human HEK293
MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion an...
TMPY-01613 Periostin/OSF-2 Protein, Mouse, Recombinant (His) Mouse HEK293
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-01020 Periostin/OSF-2 Protein, Human, Recombinant (His) Human HEK293
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-04935 CD47 Protein, Human, Recombinant (aa 1-139, His) Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-04683 CD47 Protein, Human, Recombinant Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-03093 CD47 Protein, Rat, Recombinant (His) Rat HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-05276 CD47 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-04810 CD47 Protein, Mouse, Recombinant (His) Mouse HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-01142 ICAM-1/CD54 Protein, Human, Recombinant (His) Human HEK293
Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC...
TMPY-05017 ICAM-1/CD54 Protein, Rhesus, Recombinant (His) Rhesus HEK293
Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC...
TMPY-04487 Osteomodulin Protein, Human, Recombinant (His) Human HEK293
Osteomodulin (OMD), also known as Osteoadherin (OSAD), Keratan sulfate proteoglycan osteomodulin, KSPG osteomodulin, and SLRR2C, is a secreted protein that belongs to the small leucine-rich proteoglycan (SLRP) family and...
TMPY-01349 ICAM-1/CD54 Protein, Mouse, Recombinant (His) Mouse HEK293
Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC...
TMPY-05343 CD47 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-00981 ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK) Human HEK293
Intercellular adhesion molecule-1 (ICAM-1, or CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. IC...
TMPY-01830 VCAM-1 Protein, Mouse, Recombinant (His) Mouse HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc) Human HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains...
TMPY-01288 Osteopontin Protein, Human, Recombinant (His) Human HEK293
Osteopontin, also known as Secreted phosphoprotein 1, Bone sialoprotein 1, BSP-1, OPN, and SPP1, is a member of the osteopontin family and a SIBLING glycoprotein. Osteopontin has been classified as T-helper 1 cytokine an...
TMPY-06988 Osteopontin Protein, Human, Recombinant (aa 17-166, His) Human HEK293
Osteopontin, also known as Secreted phosphoprotein 1, Bone sialoprotein 1, BSP-1, OPN, and SPP1, is a member of the osteopontin family and a SIBLING glycoprotein. Osteopontin has been classified as T-helper 1 cytokine an...
TMPY-00803 Fibronectin Protein, Human, Recombinant (aa 607-1265, His) Human HEK293
Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet ...
TMPY-05053 ANGPTL2 Protein, Human, Recombinant (His) Human HEK293
The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-01919 MMP-9 Protein, Mouse, Recombinant Mouse HEK293
Matrix metalloproteinases (MMPs) are neutral proteinases that are involved in the breakdown and remodeling of the extracellular matrix (ECM) under a variety of physiological and pathological conditions, such as morphogen...
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Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His)
TMPY-04643
Species: Mouse
Expression System: HEK293
Integrin alpha V beta 3 Protein, Human, Recombinant (His)
TMPY-05716
Species: Human
Expression System: HEK293
Integrin alpha V beta 8 Protein, Human, Recombinant (His)
TMPY-05717
Species: Human
Expression System: HEK293
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293
Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His)
TMPY-02159
Species: Human
Expression System: HEK293
Integrin alpha 8 beta 1 Protein, Human, Recombinant (Flag & His)
TMPY-02160
Species: Human
Expression System: HEK293
Integrin alpha 6 beta 4 Protein, Human, Recombinant (Flag & His)
TMPY-04881
Species: Human
Expression System: HEK293
Integrin alpha X beta 2 Protein, Human, Recombinant (His)
TMPY-05762
Species: Human
Expression System: HEK293
Integrin alpha 6 beta 1 Protein, Human, Recombinant (Flag & His)
TMPY-02158
Species: Human
Expression System: HEK293
Integrin alpha X beta 2 Protein, Human, Recombinant (Flag & His)
TMPY-02161
Species: Human
Expression System: HEK293
ITGB1 Protein, Human, Recombinant (His)
TMPY-00476
Species: Human
Expression System: HEK293
CD47 Protein, Human, Recombinant (His)
TMPJ-00211
Species: Human
Expression System: Human Cells
ITGB6 Protein, Human, Recombinant (His)
TMPK-00839
Species: Human
Expression System: HEK293
ITGB6 Protein, Mouse, Recombinant (His)
TMPK-01247
Species: Mouse
Expression System: HEK293
ITGA5 Protein, Human, Recombinant (His)
TMPJ-00810
Species: Human
Expression System: Human Cells
CIB2 Protein, Human, Recombinant (His)
TMPY-02289
Species: Human
Expression System: E. coli
ITGB1 Protein, Human, Recombinant (aa 21-728, His)
TMPJ-00786
Species: Human
Expression System: Human Cells
ILKAP Protein, Human, Recombinant (His)
TMPY-02198
Species: Human
Expression System: HEK293
CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
TMPJ-00614
Species: Rhesus Macaque
Expression System: Human Cells
CD47 Protein, Human, Recombinant (mFc)
TMPJ-00212
Species: Human
Expression System: Human Cells
CD47 Protein, Rhesus macaque, Recombinant (hFc)
TMPJ-00613
Species: Rhesus macaque
Expression System: Human Cells
IBSP Protein, Mouse, Recombinant (His)
TMPJ-00445
Species: Mouse
Expression System: Human Cells
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPJ-00208
Species: Human
Expression System: Human Cells
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00209
Species: Human
Expression System: Human Cells
PARVA Protein, Human, Recombinant (His)
TMPJ-00242
Species: Human
Expression System: E. coli
Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)
TMPH-00213
Species: Bothrops atrox
Expression System: E. coli
WISP2/CCN5 Protein, Mouse, Recombinant (His)
TMPH-02569
Species: Mouse
Expression System: Yeast
CD31/PECAM-1 Protein, Human, Recombinant (His)
TMPY-00970
Species: Human
Expression System: HEK293
MZB1/PERP1 Protein, Human, Recombinant (His)
TMPY-03630
Species: Human
Expression System: HEK293
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
TMPY-01613
Species: Mouse
Expression System: HEK293
Periostin/OSF-2 Protein, Human, Recombinant (His)
TMPY-01020
Species: Human
Expression System: HEK293
CD47 Protein, Human, Recombinant (aa 1-139, His)
TMPY-04935
Species: Human
Expression System: HEK293
CD47 Protein, Human, Recombinant
TMPY-04683
Species: Human
Expression System: HEK293
CD47 Protein, Rat, Recombinant (His)
TMPY-03093
Species: Rat
Expression System: HEK293
CD47 Protein, Human, Recombinant, Biotinylated
TMPY-05191
Species: Human
Expression System: HEK293
CD47 Protein, Cynomolgus, Recombinant (hFc)
TMPY-05276
Species: Cynomolgus
Expression System: HEK293
CD47 Protein, Mouse, Recombinant (His)
TMPY-04810
Species: Mouse
Expression System: HEK293
ICAM-1/CD54 Protein, Human, Recombinant (His)
TMPY-01142
Species: Human
Expression System: HEK293
ICAM-1/CD54 Protein, Rhesus, Recombinant (His)
TMPY-05017
Species: Rhesus
Expression System: HEK293
Osteomodulin Protein, Human, Recombinant (His)
TMPY-04487
Species: Human
Expression System: HEK293
ICAM-1/CD54 Protein, Mouse, Recombinant (His)
TMPY-01349
Species: Mouse
Expression System: HEK293
CD47 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-05343
Species: Cynomolgus,Rhesus
Expression System: HEK293
ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK)
TMPY-00981
Species: Human
Expression System: HEK293
VCAM-1 Protein, Mouse, Recombinant (His)
TMPY-01830
Species: Mouse
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (hFc)
TMPY-00947
Species: Human
Expression System: HEK293
Osteopontin Protein, Human, Recombinant (His)
TMPY-01288
Species: Human
Expression System: HEK293
Osteopontin Protein, Human, Recombinant (aa 17-166, His)
TMPY-06988
Species: Human
Expression System: HEK293
Fibronectin Protein, Human, Recombinant (aa 607-1265, His)
TMPY-00803
Species: Human
Expression System: HEK293
ANGPTL2 Protein, Human, Recombinant (His)
TMPY-05053
Species: Human
Expression System: HEK293
MMP-9 Protein, Mouse, Recombinant
TMPY-01919
Species: Mouse
Expression System: HEK293
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