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Search Results for " leukemia "

Targets

503

Compounds

85

Natural Products

189

Recombinant Proteins

3

Libraries

Cat No. Product Name Synonyms Targets
T79921 Moloney murine leukemia virus RT DNA/RNA Synthesis
Moloney murine leukemia virus reverse transcriptase (MMLV RT) is a monomeric replicative polymerase intrinsic to the retrovirus life cycle [1].
T72098 Eleven-Nineteen-Leukemia Protein IN-3 Epigenetic Reader Domain
Eleven-Nineteen-Leukemia Protein IN-3, an orally active ENL YEATS domain inhibitor, exhibits potent activity with an IC50 of 15.4 nM. It downregulates MYC expression via ENL in cells and enhances ENL protein's thermal st...
T72097 Eleven-Nineteen-Leukemia Protein IN-2 Epigenetic Reader Domain
Eleven-Nineteen-Leukemia Protein IN-2 (compound 23), an ENL inhibitor, exhibits an IC50 of 10.7 nM and is utilized for leukemia research [1].
T72096 Eleven-Nineteen-Leukemia Protein IN-1 Epigenetic Reader Domain
Eleven-Nineteen-Leukemia Protein IN-1 is a potent inhibitor of the ENL YEATS domain, exhibiting an IC50 of 14.5 nM. It binds to the ENL protein, consequently increasing its thermal stability in vitro [1].
T7664 Pyroxamide Apoptosis , HDAC
Pyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).
T9339 Stafia-1 STAT
Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.
T12246 CB-103 Gamma-secretase
CB-103 is a orally active inhibitor of notch signaling pathway, with anti-tumor activity.
T13186 TL02-59 Apoptosis , Src , Hck
TL02-59 is a selective inhibitor of Fgr in Src-family kinase (IC50 = 0.03 nM). TL02-59 inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. TL02-59 potently suppresses acute myelogenous leukemia cell growt...
T7138 FB23-2 Apoptosis , Others
FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).
T9041 AES-350 Apoptosis , HDAC
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, ...
T13950 UC-514321 Apoptosis , STAT
UC-514321 directly targets STAT3/5 and represses TET1 expression. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity.
T9629 BRD4 Inhibitor-24 Epigenetic Reader Domain
BRD4 Inhibitor-24 is a BRD4 small molecule inhibitor with antitumor activity.
T16363 NVP-2 Apoptosis , CDK
NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB, CD...
T7200 TAK-960 PLK
TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.
T12943 SNDX-5613 Epigenetic Reader Domain , Histone Methyltransferase
SNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM). SNDX-5613 can be used for the research of MLL-rearranged (MLL-r) acute leukemias.
T41248 Thiocolchicine Microtubule Associated
Thiocolchicine is an effective inhibitor of tubulin polymerization with an IC50 of 2.5 µM and a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.
T7955 EB-3D Apoptosis , AMPK , AChR
EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.
T1803 GNF-5 GNF 5 SARS-CoV , Bcr-Abl
GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22±0.1 uM, Wild-type Abl). It is an analog of GNF-2 with improved pharmacokinetic properties.
T64338 AKI603 AKI 603,AKI-603 Aurora Kinase
AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in l...
T3082 SGC0946 Histone Methyltransferase
SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.
T9744 MP07-66 Phosphatase
MP07-66 is a novel FTY720-analog devoid of immunosuppressive effects leads to the reactivation of PP2A, which in turn triggers apoptosis of CLL cells.
T16766 Ro 08-2750
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM. Ro 08-2...
T9573 GSK3685032 DNA Methyltransferase
GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM). The inhibitory effect is time-independent and reversible. GSK3685032 induces loss of DNA methylation and transcriptional activation and inhibits c...
T9014 SKI-178 Apoptosis , S1P Receptor
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ...
T8308 NL-1 Mitochondrial Metabolism , Autophagy
NL-1 is a mitoNEET inhibitor with antileukemic effect.
T1843 XMD8-92 ERK , BMI-1 , Epigenetic Reader Domain
XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).
T13336 VTP50469 Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
T24269 KPT-251 KPT251 Others
KPT-251 is a selective nuclear export inhibitor.
T8882 Vodobatinib K-0706 Bcr-Abl
Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.
T14371 Barasertib AZD1152 Apoptosis , Aurora Kinase
AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
T12317 Orelabrutinib ICP-022 BTK
Orelabrutinib (ICP-022) is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK).
T3196 GNF-7 GNF7 Bcr-Abl , ACK , AChR
GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.
T9399 Menin-MLL inhibitor 20 Epigenetic Reader Domain , Histone Methyltransferase
Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.
T12575 Unesbulin PTC596 Apoptosis , BMI-1
Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).
T9705 TL-895 BTK
TL-895 is an ATP-competitive, and highly selective irreversible inhibitor of Bruton’s Tyrosine Kinase(BTK). TL-895 showed good potency with an IC50 of 1.5 nM and a Ki of 11.9 nM.
T14919 CDKI-73 Apoptosis , CDK
CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).The inhibition of CDK9 induces apoptosis and potentiates the effe...
T16557 PNU-159682 Topoisomerase
PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin. PNU-159682 has outstanding cytotoxicity. PNU-159682 is an effective ADCs cytotoxin.
T8003 Methotrexate disodium Apoptosis , Dehydrogenase , DNA/RNA Synthesis , Antifolate
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor
T13166 TK216 Others , DNA/RNA Synthesis
TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.
T6609 NMS-E973 HSP
NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.
T28036 MI-2-2 MI22,MI 2 2 Histone Methyltransferase
MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.
T3278 Piribedil EU-4200,Trivastan,ET-495,Trivastal Dopamine Receptor , Histone Methyltransferase , Adrenergic Receptor
Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
T10606 BRD0705 GSK-3
BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor (IC50: 66 nM; Kd: 4.8 μM). BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50: 515 nM).
T38562 AKN-028 FLT
AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.
T9552 BAZ1A-IN-1 Epigenetic Reader Domain
BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-survival activity against cancer cell lines with high BAZ1A expression, but weak or no activity ag...
TP1115 L-Asparaginase L-​ASNase Others
L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-a...
T2620 G-749 G749 Apoptosis , FLT , c-RET , TAM Receptor , Aurora Kinase
G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.
T7188 Piclidenoson CF-101,IB-MECA Apoptosis , Adenosine Receptor
Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.
T7007 UNC2025 mrx-6313,UNC-2025,UNC 2025 FLT , TAM Receptor
UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
T21785 AG957 Bcr-Abl
Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling in chronic myelogenous leukemia hematopoietic progenitors[1].

Compounds

Moloney murine leukemia virus RT
T79921
Synonym:
Target: DNA/RNA Synthesis
Eleven-Nineteen-Leukemia Protein IN-3
T72098
Synonym:
Target: Epigenetic Reader Domain
Eleven-Nineteen-Leukemia Protein IN-2
T72097
Synonym:
Target: Epigenetic Reader Domain
Eleven-Nineteen-Leukemia Protein IN-1
T72096
Synonym:
Target: Epigenetic Reader Domain
Pyroxamide
T7664
Synonym:
Target: Apoptosis, HDAC
Stafia-1
T9339
Synonym:
Target: STAT
CB-103
T12246
Synonym:
Target: Gamma-secretase
TL02-59
T13186
Synonym:
Target: Apoptosis, Src, Hck
FB23-2
T7138
Synonym:
Target: Apoptosis, Others
AES-350
T9041
Synonym:
Target: Apoptosis, HDAC
UC-514321
T13950
Synonym:
Target: Apoptosis, STAT
BRD4 Inhibitor-24
T9629
Synonym:
Target: Epigenetic Reader Domain
NVP-2
T16363
Synonym:
Target: Apoptosis, CDK
TAK-960
T7200
Synonym:
Target: PLK
SNDX-5613
T12943
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
Thiocolchicine
T41248
Synonym:
Target: Microtubule Associated
EB-3D
T7955
Synonym:
Target: Apoptosis, AMPK, AChR
GNF-5
T1803
Synonym: GNF 5
Target: SARS-CoV, Bcr-Abl
AKI603
T64338
Synonym: AKI 603,AKI-603
Target: Aurora Kinase
SGC0946
T3082
Synonym:
Target: Histone Methyltransferase
MP07-66
T9744
Synonym:
Target: Phosphatase
Ro 08-2750
T16766
Synonym:
Target:
GSK3685032
T9573
Synonym:
Target: DNA Methyltransferase
SKI-178
T9014
Synonym:
Target: Apoptosis, S1P Receptor
NL-1
T8308
Synonym:
Target: Mitochondrial Metabolism, Autophagy
XMD8-92
T1843
Synonym:
Target: ERK, BMI-1, Epigenetic Reader Domain
VTP50469
T13336
Synonym:
Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase
KPT-251
T24269
Synonym: KPT251
Target: Others
Vodobatinib
T8882
Synonym: K-0706
Target: Bcr-Abl
Barasertib
T14371
Synonym: AZD1152
Target: Apoptosis, Aurora Kinase
Orelabrutinib
T12317
Synonym: ICP-022
Target: BTK
GNF-7
T3196
Synonym: GNF7
Target: Bcr-Abl, ACK, AChR
Menin-MLL inhibitor 20
T9399
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
Unesbulin
T12575
Synonym: PTC596
Target: Apoptosis, BMI-1
TL-895
T9705
Synonym:
Target: BTK
CDKI-73
T14919
Synonym:
Target: Apoptosis, CDK
PNU-159682
T16557
Synonym:
Target: Topoisomerase
Methotrexate disodium
T8003
Synonym:
Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate
TK216
T13166
Synonym:
Target: Others, DNA/RNA Synthesis
NMS-E973
T6609
Synonym:
Target: HSP
MI-2-2
T28036
Synonym: MI22,MI 2 2
Target: Histone Methyltransferase
Piribedil
T3278
Synonym: EU-4200,Trivastan,ET-495,Trivastal
Target: Dopamine Receptor, Histone Methyltransferase, Adrenergic Receptor
BRD0705
T10606
Synonym:
Target: GSK-3
AKN-028
T38562
Synonym:
Target: FLT
BAZ1A-IN-1
T9552
Synonym:
Target: Epigenetic Reader Domain
L-Asparaginase
TP1115
Synonym: L-​ASNase
Target: Others
G-749
T2620
Synonym: G749
Target: Apoptosis, FLT, c-RET, TAM Receptor, Aurora Kinase
Piclidenoson
T7188
Synonym: CF-101,IB-MECA
Target: Apoptosis, Adenosine Receptor
UNC2025
T7007
Synonym: mrx-6313,UNC-2025,UNC 2025
Target: FLT, TAM Receptor
AG957
T21785
Synonym:
Target: Bcr-Abl
1 2 3 4 5 6 7 8 9 10 11
Cat No. Product Name Synonyms Targets
T6S1435 Notopterol Apoptosis , Others
1. Notopterol induces apoptosis and inhibits cell cycle-specific.
T3020 Sclareol Apoptosis , Others
Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human Y cell lines.
T37341 N-Acetyltyramine Antibacterial
N-acetyltyramine is a metabolite of the biogenic amine tyramine . It enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells with an IC50 value of 0.13 μg/ml compared with an IC50 value of 0.48 μg/ml...
TN6512 Tectol Transferase , Parasite
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatiti...
T9715 Aplidine SARS-CoV , DNA/RNA Synthesis
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM).
T3843 Pinosylvin 3,5-stilbenediol,5-Styrylresorcinol Apoptosis , Others , Antibacterial , Autophagy
Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.
TN1684 Ginsenoside F5 Apoptosis
Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway
T1882 Meisoindigo N-Methylisoindigotin,Methylisoindigotin,Natura-α,Dian III Apoptosis
Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).
TJS0328 Nordalbergin 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One Others
Nordalbergin is a natural product for research related to life sciences. The catalog number is TJS0328 and the CAS number is 482-82-6.
T0132 Etoposide VP-16,VP-16-213 Apoptosis , Mitophagy , Topoisomerase , Antibacterial , Antibiotic , Autophagy
Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM). Etoposide has antitumor activity and induces apoptosis and autophagy.
T1511 Daunorubicin hydrochloride Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin Apoptosis , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic , Autophagy
Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein synthesis.
T1166 Ellipticine NSC 71795,Elliptisine Topoisomerase
Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-6...
T4745 4-Carboxyquinoline QUINOLINE-4-CARBOXYLIC ACID,4-Quinolinecarboxylic acid Others , Endogenous Metabolite
4-Carboxyquinoline (4-Quinolinecarboxylic acid) showed anti-tumor activity against L1210 leukemia and B16 melanoma.
T8188 Podophyllotoxone Others , Microtubule Associated
Podophyllotoxinone, a natural compound found in Dysosma versipellis, shows inhibitory activity against L1210 leukemia and KB cells in vitro.
TQ0213 Bruceantin (-)-Bruceantin,NCI165563,NSC165563 Others
Bruceantin (NSC-165563) is a natural product isolated from Brucea antidysenterica. Bruceantin has antitumor activity against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice.
T8292 (-)-Cedrene Alpha-Cedrene Others , Antibacterial
(-)-Cedrene (Alpha-Cedrene) is a sesquiterpene from cedar oil that has anti-leukemia, antibacterial and anti-obesity properties.
TN3543 Bruceoside A Others
Bruceoside A is a bitter wood glycoside that can be isolated from opuntia and has anticancer and tumor activity and can be used with the study of leukemia.
TN1369 Alloimperatorin Prangenidin Others
Alloimperatorin (Prangenidin) exhibits in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition of cell migration. It photosensitizes efficient...
T34398 Rotundifuran Others
Rotundifuran is extracted from the fruit of Vitex rotundifolia. Rotundifuran inhibits cell cycle progression and induces apoptosis in human myeloid leukemia cells.
T5S1923 Schisandrin C Schizandrin-C,Wuweizisu-C Apoptosis , Others , Virus Protease
Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.
T6S0234 Toosendanin Others
1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. 3. Toosendanin i...
TN1258 3-Acetyl-beta-boswellic acid 3-O-Acetyl-beta-boswellic acid DNA/RNA Synthesis
3-Acetyl-beta-boswellic acid has antitumor activity, it inhibits synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner with IC50 values ranging from 0.6 to 7.1 microM.
T25476 Gypsogenin 639-14-5 Bcr-Abl
Gypsogenin (639-14-5) is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities.
TN1569 Deoxylapachol Antifection , Antifungal
Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevi...
T1086 Vitamin D2 Calciferol,Ergocalciferol,Ercalciol DNA/RNA Synthesis , Endogenous Metabolite
Ergocalciferol (Vitamin D2 (Calciferol)) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond with a strong inhibitory effect against bladder tumor promotion by sodium saccharin, and it in...
T4036 Solasodine Solancarpidine,Purapuridine,Solasodin Apoptosis , Others , E1/E2/E3 Enzyme , Antifungal
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer cell line (HeLa) and huma...
T13354 Xanthoangelol Apoptosis , Monoamine Transporter , Antibacterial , AMPK
Xanthoangelol, which can be extracted from Angelica keiskei, inhibits obesity-induced inflammatory responses.Xanthoangelol has antimicrobial activity, inhibits monoamine oxidase, and induces apoptosis in neuroblastoma an...
T11060 DMAPT Dimethylamino Parthenolide NF-κB
DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells.
TL0013 Heraclenin Anti-infection , Immunology/Inflammation related
Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat leukemia cells, it has a strong clastogenic effect . (+)-Her...
T5278 5-Hydroxymethyl-2-furancarboxylic acid Sumiki's acid,5-(Hydroxymethyl)-2-furoic acid Others , Endogenous Metabolite
5-Hydroxymethyl-2-furancarboxylic acid (5-(Hydroxymethyl)-2-furoic acid) (Sumiki's acid) is a naturally occurring human metabolite. Sumiki's acid was first identified in the urine of a leukemia patient who was excreting ...
TN1215 (2S)-2'-Methoxykurarinone 2'-Methoxykurarinone,2'-O-Methylkurarinone Akt , Antifection
(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone inhibits osteo...
T3380 Homoharringtonine Myelostat,Ceflatonin,HHT,Omacetaxine mepesuccinate STAT
Homoharringtonine (HHT) is an alkaloid inhibitor of protein synthesis with activity in myeloid malignancies. It might have clinical activity in some patients with myelodysplastic syndrome. Homoharringtonine enhances the ...
T36528 Illudin M Apoptosis , DNA Alkylator/Crosslinker
Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It has a cytotoxicity of 6-100 nM against HL-60 human leukemia cells.Illudin M has anticancer activity and is a pre-drug for the synt...
T5244 Aminomalonic acid 2-Aminopropanedioic Acid,Aminomalonate Others , Endogenous Metabolite
Aminomalonic acid (Aminomalonate) (Ama) was first detected in alkaline hydrolysates of proteins in 1984. Ama has been isolated from proteins of Escherichia coli and human atherosclerotic plaque. The presence of Ama has i...
T4S1335 Daphnoretin Dephnoretin,Thymelol Influenza Virus , Caspase , PKC
1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through ...
T4S1943 Kirenol Kirel Wnt/beta-catenin
1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid...
T5S0045 Isofraxidin 6,8-Dimethoxyumbelliferone,Phytodolor MMP , ERK , p38 MAPK , TLR , COX
1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the prote...
T2924 Phloretin Dihydronaringenin,NSC 407292,RJC 02792 SGLT , transporter , Endogenous Metabolite
Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leav...
T3S0209 Vincristine ERK , p38 MAPK , NF-κB , Akt , JNK , mTOR
Vincristine binds to tubulin and inhibits the formation of microtubules, thereby inhibiting mitosis of the cancer cell. Vincristine can be used as a microtubule-destabilizing agent for research on the treatment of hemato...
TN1880 Lucidenic acid B Lucidenicacid B Apoptosis , Caspase
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito...
T3S1553 Trans-Cinnamaldehyde Cinnamaldehyde,Cinnamic aldehyde,Cinnamal,Phenylacrolein COX , Endogenous Metabolite
1. trans-Cinnamaldehyde (Phenylacrolein) exhibits excellent anti-inflammatory activities and antidepressant-like effects in stressed mid-aged rats as a COX-2 inhibitor. 2. Cinnamic aldehyde induces apoptosis of CML cells...
TN2211 Silybin B Silibinin B Apoptosis , Beta Amyloid , Bcr-Abl
Silybin B (Silibinin B) is an effective inhibitor of raloxifene 4 '- and 6-glucosalylation, an effective anti-fibrinogenic and anti-oligomeric component of Silymarin, with free radical scavenging activity of 1, 1-dipheny...
T6S1315 Oroxylin A 6-Methoxybaicalein,Baicalein 6-methyl ether Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...
T4S0797 Berberine Berberin,Umbellatine Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
TN2835 28-Deoxonimbolide Caspase
28-Deoxonimbolide exhibits potent cytotoxic activity against HL60 leukemia cells.
TN6054 Norglaucine hydrochloride
(+)-Norglaucine shows cytotoxic activity toward the tumor cell lines B16-F10 (mouse melanoma), HepG2 (human hepatocellular carcinoma), K562 (human chronic myelocytic leukemia) and HL-60 (human promyelocytic leukemia) and...
TN5358 Eupahualin C
Eupahualin C shows significant activities against cell lines of human chronic myelogenous leukemia (K562) and human bone cancer (U2OS).
TN5585 14-Deoxy-11-hydroxyandrographolide
14-Deoxy-11-hydroxyandrographolide shows potent cell differentiation-inducing activity towards mouse myeloid leukemia (M1) cells.
T2S0606 Bakkenolide A IL Receptor , IκB/IKK , GSK-3 , TNF , Akt , Caspase , PI3K , HDAC
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways.
T75453 11-epi-Chaetomugilin I
11-epi-Chaetomugilin I is a metabolite found in Chaetomium globosum . 11-epi-Chaetomugilin I exhibits significant cytotoxic activity against the murine P388 leukemia cell line, the human HL-60 leukemia cell line, the mur...
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Natural Products

Notopterol
T6S1435
Synonym:
Target: Apoptosis, Others
Sclareol
T3020
Synonym:
Target: Apoptosis, Others
N-Acetyltyramine
T37341
Synonym:
Target: Antibacterial
Tectol
TN6512
Synonym:
Target: Transferase, Parasite
Aplidine
T9715
Synonym:
Target: SARS-CoV, DNA/RNA Synthesis
Pinosylvin
T3843
Synonym: 3,5-stilbenediol,5-Styrylresorcinol
Target: Apoptosis, Others, Antibacterial, Autophagy
Ginsenoside F5
TN1684
Synonym:
Target: Apoptosis
Meisoindigo
T1882
Synonym: N-Methylisoindigotin,Methylisoindigotin,Natura-α,Dian III
Target: Apoptosis
Nordalbergin
TJS0328
Synonym: 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One
Target: Others
Etoposide
T0132
Synonym: VP-16,VP-16-213
Target: Apoptosis, Mitophagy, Topoisomerase, Antibacterial, Antibiotic, Autophagy
Daunorubicin hydrochloride
T1511
Synonym: Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin
Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic, Autophagy
Ellipticine
T1166
Synonym: NSC 71795,Elliptisine
Target: Topoisomerase
4-Carboxyquinoline
T4745
Synonym: QUINOLINE-4-CARBOXYLIC ACID,4-Quinolinecarboxylic acid
Target: Others, Endogenous Metabolite
Podophyllotoxone
T8188
Synonym:
Target: Others, Microtubule Associated
Bruceantin
TQ0213
Synonym: (-)-Bruceantin,NCI165563,NSC165563
Target: Others
(-)-Cedrene
T8292
Synonym: Alpha-Cedrene
Target: Others, Antibacterial
Bruceoside A
TN3543
Synonym:
Target: Others
Alloimperatorin
TN1369
Synonym: Prangenidin
Target: Others
Rotundifuran
T34398
Synonym:
Target: Others
Schisandrin C
T5S1923
Synonym: Schizandrin-C,Wuweizisu-C
Target: Apoptosis, Others, Virus Protease
Toosendanin
T6S0234
Synonym:
Target: Others
3-Acetyl-beta-boswellic acid
TN1258
Synonym: 3-O-Acetyl-beta-boswellic acid
Target: DNA/RNA Synthesis
Gypsogenin
T25476
Synonym: 639-14-5
Target: Bcr-Abl
Deoxylapachol
TN1569
Synonym:
Target: Antifection, Antifungal
Vitamin D2
T1086
Synonym: Calciferol,Ergocalciferol,Ercalciol
Target: DNA/RNA Synthesis, Endogenous Metabolite
Solasodine
T4036
Synonym: Solancarpidine,Purapuridine,Solasodin
Target: Apoptosis, Others, E1/E2/E3 Enzyme, Antifungal
Xanthoangelol
T13354
Synonym:
Target: Apoptosis, Monoamine Transporter, Antibacterial, AMPK
DMAPT
T11060
Synonym: Dimethylamino Parthenolide
Target: NF-κB
Heraclenin
TL0013
Synonym:
Target: Anti-infection, Immunology/Inflammation related
5-Hydroxymethyl-2-furancarboxylic acid
T5278
Synonym: Sumiki's acid,5-(Hydroxymethyl)-2-furoic acid
Target: Others, Endogenous Metabolite
(2S)-2'-Methoxykurarinone
TN1215
Synonym: 2'-Methoxykurarinone,2'-O-Methylkurarinone
Target: Akt, Antifection
Homoharringtonine
T3380
Synonym: Myelostat,Ceflatonin,HHT,Omacetaxine mepesuccinate
Target: STAT
Illudin M
T36528
Synonym:
Target: Apoptosis, DNA Alkylator/Crosslinker
Aminomalonic acid
T5244
Synonym: 2-Aminopropanedioic Acid,Aminomalonate
Target: Others, Endogenous Metabolite
Daphnoretin
T4S1335
Synonym: Dephnoretin,Thymelol
Target: Influenza Virus, Caspase, PKC
Kirenol
T4S1943
Synonym: Kirel
Target: Wnt/beta-catenin
Isofraxidin
T5S0045
Synonym: 6,8-Dimethoxyumbelliferone,Phytodolor
Target: MMP, ERK, p38 MAPK, TLR, COX
Phloretin
T2924
Synonym: Dihydronaringenin,NSC 407292,RJC 02792
Target: SGLT, transporter, Endogenous Metabolite
Vincristine
T3S0209
Synonym:
Target: ERK, p38 MAPK, NF-κB, Akt, JNK, mTOR
Lucidenic acid B
TN1880
Synonym: Lucidenicacid B
Target: Apoptosis, Caspase
trans-Cinnamaldehyde
T3S1553
Synonym: Cinnamaldehyde,Cinnamic aldehyde,Cinnamal,Phenylacrolein
Target: COX, Endogenous Metabolite
Silybin B
TN2211
Synonym: Silibinin B
Target: Apoptosis, Beta Amyloid, Bcr-Abl
Oroxylin A
T6S1315
Synonym: 6-Methoxybaicalein,Baicalein 6-methyl ether
Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy
Berberine
T4S0797
Synonym: Berberin,Umbellatine
Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy
28-Deoxonimbolide
TN2835
Synonym:
Target: Caspase
Norglaucine hydrochloride
TN6054
Synonym:
Target:
Eupahualin C
TN5358
Synonym:
Target:
14-Deoxy-11-hydroxyandrographolide
TN5585
Synonym:
Target:
Bakkenolide A
T2S0606
Synonym:
Target: IL Receptor, IκB/IKK, GSK-3, TNF, Akt, Caspase, PI3K, HDAC
11-epi-Chaetomugilin I
T75453
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04278 LIF Protein, Mouse, Recombinant Mouse HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-03532 LIF Protein, Human, Recombinant (His) Human HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-00991 LIFR Protein, Human, Recombinant (His) Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-05493 LIFR Protein, Human, Recombinant (hFc) Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-04104 LIF Protein, Human, Recombinant Human HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPJ-00235 TPO Protein, Human, Recombinant (His) Human Human Cells
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of me...
TMPY-06952 LIF Protein, Cynomolgus, Rhesus, Recombinant (His & Avi), Biotinylated Cynomolgus,Rhesus HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-02460 LIF Protein, Mouse, Recombinant (His) Mouse HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-06892 LIFR Protein, Rhesus, Recombinant (His) Rhesus HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-03306 LIFR Protein, Rat, Recombinant (His) Rat HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-01597 LIFR Protein, Mouse, Recombinant (His) Mouse HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPH-02465 Moloney murine leukemia virus (MoMLV) (isolate Shinnick) Gag polyprotein (GST) MoMLV E. coli
TMPY-03555 LIF Protein, Human, Recombinant (hFc) Human HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-02518 TCL1A Protein, Human, Recombinant (His) Human E. coli
T-cell leukemia/lymphoma protein 1A (abbreviated for TCL1A) is a member of the TCL1 family. TCL1 protooncogene is expressed in CD3-CD4-CD8-precursor T cells and is extinguished at the CD4+CD8+stage of thymocyte developme...
TMPY-06010 LIFR Protein, Human, Recombinant (His), Biotinylated Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-05242 CRLF2/TSLPR Protein, Human, Recombinant (His) Human HEK293
Overexpression of cytokine receptor-like factor 2 (CRLF2) due to chromosomal rearrangement has been observed in acute lymphoblastic leukemia (ALL) and reported to contribute to oncogenesis and unfavorable outcome in ALL....
TMPY-05081 Notch 1 Protein, Human, Recombinant (hFc) Human HEK293
NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair...
TMPY-02646 NSE/ENO2 Protein, Human, Recombinant (His) Human E. coli
The combination of silencing ENO2 and 2-deoxyglucose (2-DG) synergistically inhibited leukemia cell survival. ENO2 may be a biological marker for monitoring chemotherapeutic efficacy and relapse in ALL. Reduced ENO2 expr...
TMPY-01410 IL-3R alpha/CD123 Protein, Human, Recombinant (His) Human HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-01648 TREML2 Protein, Human, Recombinant (His) Human HEK293
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like...
TMPY-01935 C-Kit Protein, Human, Recombinant (His) Human HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-01802 C-Kit Protein, Mouse, Recombinant (His) Mouse HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-02279 Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His) Human E. coli
Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key en...
TMPY-01462 IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) Human HEK293
Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, includi...
TMPY-05655 C-Kit Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-04051 C-Kit Protein, Human, Recombinant (hFc) Human HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-01250 IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, includi...
TMPY-00939 Thrombopoietin Protein, Mouse, Recombinant (His) Mouse HEK293
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His) Human HEK293
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66...
TMPY-02312 CSF3R/G-CSFR Protein, Human, Recombinant (His) Human HEK293
Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3 (CSF3). It is a critical regula...
TMPY-00665 Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) Human HEK293
Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 fam...
TMPJ-01467 Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) Human E.coli
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ...
TMPY-03835 CDCP1 Protein, Rhesus, Recombinant (His) Rhesus HEK293
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-02409 Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-03805 Siglec-3/CD33 Protein, Human, Recombinant (His) Human HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-01257 UPAR/PLAUR Protein, Mouse, Recombinant (His) Mouse HEK293
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ...
TMPY-02304 Siglec-3/CD33 Protein, Mouse, Recombinant (His) Mouse HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-04952 Siglec-3/CD33 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-04298 CDCP1 Protein, Human, Recombinant (His) Human HEK293
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-01076 Gp130/IL6ST Protein, Human, Recombinant (His & hFc) Human HEK293
Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines...
TMPY-01832 Gp130/IL6ST Protein, Mouse, Recombinant (His) Mouse HEK293
Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines...
TMPY-01023 CD38 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03923 CD38 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-04805 Siglec-3/CD33 Protein, Human, Recombinant Human HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-02700 BCL2 Protein, Human, Recombinant (His) Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPY-02141 UPAR/PLAUR Protein, Human, Recombinant (His) Human HEK293
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ...
TMPY-05573 CD38 Protein, Human, Recombinant (His), PE conjugated Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01815 FOLR1 Protein, Human, Recombinant (His) Human HEK293
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i...
TMPY-06022 FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i...
TMPY-04548 CDK4 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cel...
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LIF Protein, Mouse, Recombinant
TMPY-04278
Species: Mouse
Expression System: HEK293
LIF Protein, Human, Recombinant (His)
TMPY-03532
Species: Human
Expression System: HEK293
LIFR Protein, Human, Recombinant (His)
TMPY-00991
Species: Human
Expression System: HEK293
LIFR Protein, Human, Recombinant (hFc)
TMPY-05493
Species: Human
Expression System: HEK293
LIF Protein, Human, Recombinant
TMPY-04104
Species: Human
Expression System: HEK293
TPO Protein, Human, Recombinant (His)
TMPJ-00235
Species: Human
Expression System: Human Cells
LIF Protein, Cynomolgus, Rhesus, Recombinant (His & Avi), Biotinylated
TMPY-06952
Species: Cynomolgus,Rhesus
Expression System: HEK293
LIF Protein, Mouse, Recombinant (His)
TMPY-02460
Species: Mouse
Expression System: HEK293
LIFR Protein, Rhesus, Recombinant (His)
TMPY-06892
Species: Rhesus
Expression System: HEK293
LIFR Protein, Rat, Recombinant (His)
TMPY-03306
Species: Rat
Expression System: HEK293
LIFR Protein, Mouse, Recombinant (His)
TMPY-01597
Species: Mouse
Expression System: HEK293
Moloney murine leukemia virus (MoMLV) (isolate Shinnick) Gag polyprotein (GST)
TMPH-02465
Species: MoMLV
Expression System: E. coli
LIF Protein, Human, Recombinant (hFc)
TMPY-03555
Species: Human
Expression System: HEK293
TCL1A Protein, Human, Recombinant (His)
TMPY-02518
Species: Human
Expression System: E. coli
LIFR Protein, Human, Recombinant (His), Biotinylated
TMPY-06010
Species: Human
Expression System: HEK293
CRLF2/TSLPR Protein, Human, Recombinant (His)
TMPY-05242
Species: Human
Expression System: HEK293
Notch 1 Protein, Human, Recombinant (hFc)
TMPY-05081
Species: Human
Expression System: HEK293
NSE/ENO2 Protein, Human, Recombinant (His)
TMPY-02646
Species: Human
Expression System: E. coli
IL-3R alpha/CD123 Protein, Human, Recombinant (His)
TMPY-01410
Species: Human
Expression System: HEK293
TREML2 Protein, Human, Recombinant (His)
TMPY-01648
Species: Human
Expression System: HEK293
c-Kit Protein, Human, Recombinant (His)
TMPY-01935
Species: Human
Expression System: HEK293
c-Kit Protein, Mouse, Recombinant (His)
TMPY-01802
Species: Mouse
Expression System: HEK293
Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His)
TMPY-02279
Species: Human
Expression System: E. coli
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
TMPY-01462
Species: Human
Expression System: HEK293
c-Kit Protein, Rhesus, Recombinant (hFc)
TMPY-05655
Species: Rhesus
Expression System: HEK293
c-Kit Protein, Human, Recombinant (hFc)
TMPY-04051
Species: Human
Expression System: HEK293
IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His)
TMPY-01250
Species: Mouse
Expression System: HEK293
Thrombopoietin Protein, Mouse, Recombinant (His)
TMPY-00939
Species: Mouse
Expression System: HEK293
CEACAM3 Protein, Human, Recombinant (His)
TMPY-01850
Species: Human
Expression System: HEK293
CSF3R/G-CSFR Protein, Human, Recombinant (His)
TMPY-02312
Species: Human
Expression System: HEK293
Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His)
TMPY-00665
Species: Human
Expression System: HEK293
Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)
TMPJ-01467
Species: Human
Expression System: E.coli
CDCP1 Protein, Rhesus, Recombinant (His)
TMPY-03835
Species: Rhesus
Expression System: HEK293
Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-02409
Species: Cynomolgus,Rhesus
Expression System: HEK293
Siglec-3/CD33 Protein, Human, Recombinant (His)
TMPY-03805
Species: Human
Expression System: HEK293
uPAR/PLAUR Protein, Mouse, Recombinant (His)
TMPY-01257
Species: Mouse
Expression System: HEK293
Siglec-3/CD33 Protein, Mouse, Recombinant (His)
TMPY-02304
Species: Mouse
Expression System: HEK293
Siglec-3/CD33 Protein, Human, Recombinant (His), Biotinylated
TMPY-04952
Species: Human
Expression System: HEK293
CDCP1 Protein, Human, Recombinant (His)
TMPY-04298
Species: Human
Expression System: HEK293
gp130/IL6ST Protein, Human, Recombinant (His & hFc)
TMPY-01076
Species: Human
Expression System: HEK293
gp130/IL6ST Protein, Mouse, Recombinant (His)
TMPY-01832
Species: Mouse
Expression System: HEK293
CD38 Protein, Human, Recombinant (His)
TMPY-01023
Species: Human
Expression System: HEK293
CD38 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-03923
Species: Cynomolgus,Rhesus
Expression System: HEK293
Siglec-3/CD33 Protein, Human, Recombinant
TMPY-04805
Species: Human
Expression System: HEK293
BCL2 Protein, Human, Recombinant (His)
TMPY-02700
Species: Human
Expression System: E. coli
uPAR/PLAUR Protein, Human, Recombinant (His)
TMPY-02141
Species: Human
Expression System: HEK293
CD38 Protein, Human, Recombinant (His), PE conjugated
TMPY-05573
Species: Human
Expression System: HEK293
FOLR1 Protein, Human, Recombinant (His)
TMPY-01815
Species: Human
Expression System: HEK293
FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-06022
Species: Cynomolgus,Rhesus
Expression System: HEK293
CDK4 Protein, Human, Recombinant (GST)
TMPY-04548
Species: Human
Expression System: Baculovirus-Insect Cells
Cat No. Product Name
L8400 Hematonosis Compound Library

524 compounds
A unique collection of 524 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
L2140 Cancer Cell Differentiation Compound Library

413 compounds
A unique collection of 413 cancer cell differentiation inducing compounds for high throughput and high content screening;
L4300 Wnt/Hedgehog/Notch Compound Library

240 compounds
A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
TargetMol