Search Result

Search Results for " mao "

Targets

198

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T10079	MAO-IN-1		MAO
	MAO-IN-1 is a potent monoamine oxidase B (MAO B) inhibitor (IC50: 20 nM) for the study of neurologically related diseases.		MAO
T9759	MAO-B-IN-5
	MAO-B-IN-5 is a potent, selective and orally active MAO-B inhibitor with an IC 50 of 0.204 μM. MAO-B-IN-5 has the research potential in Parkinson's disease (PD) [1].
T9560	MAO-B-IN-2
	MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC 50 values of 0.51 and 7.00 μM, respectively. MAO-B-IN-2 attenuates H2O2-induced cellular damage via good ROS scavenging property.
T38034	MAO-IN-M30 dihydrochloride	M 30 dihydrochloride	Monoamine Oxidase
	MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant...		Monoamine Oxidase
T60712	MAO-B-IN-17		MAO
	MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) for the study of central nervous system disorders like Parkinson's.		MAO
T60671	MAO-B-IN-9		Beta Amyloid , Serotonin Transporter , Monoamine Oxidase
	MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence. MAO-B-IN-9 has neuroprotective effects against Aβ1-42-induced neuron...		Beta Amyloid , Serotonin Transporter , Monoamine Oxidase
T60932	MAO-B-IN-8		MAO
	MAO-B-IN-8 is a highly potent and reversible inhibitor of monoamine oxidase-B (MAO-B), which also exhibits inhibitory effects on the microglial production of neuroinflammatory mediators. This compound is specifically des...		MAO
T24430	MAO-B Inhibitor 58	MAO-B Inhibitor-58
	MAO-B inhibitor 58 is an effective, selective, and reversible inhibitor of monoamine oxidase B.
T60891	AChE/BChE/MAO-B-IN-1		MAO , AChE
	AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1...		MAO , AChE
T10154	MAO-B-IN-1		Others
	MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.		Others
T72018	MAO-B ligand-1
	MAO-B ligand-1 is a selective MAO-B inhibitor.
T78848	MAO-IN-3		Monoamine Oxidase
	MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B, effectively suppresses LN-229 glioblastoma cell proliferatio...		Monoamine Oxidase
T78690	MAO-B-IN-18		Monoamine Oxidase
	MAO-B-IN-18 is a potent, selective inhibitor of MAO B, demonstrating IC50 values of 52 nM for hMAO B and 14 μM for hMAO A. It exhibits cytoprotective effects against hydrogen peroxide-induced damage in neuroblastoma and ...		Monoamine Oxidase
T74797	MAO-B-IN-20
	MAO-B-IN-20 (Compound C14), a potent MAO-B inhibitor boasting an IC50 of 0.037 μM, demonstrates excellent metabolic stability and brain-blood barrier permeability. It holds potential for Parkinson's disease research [1].
T60651	MAO-B-IN-16
	MAO-B-IN-16 is a selective inhibitor of monoamine oxidase B (MAO-B ) (IC 50 = 1.55 μM) that can be used in the central nervous disorders study, for example, parkinson's disease [1].
T81867	MAO-B-IN-26		Autophagy
	MAO-B-IN-26 (Compound IC9) serves as both a MAO-B and acetylcholinesterase inhibitor. It safeguards SH?SY5Y cells from Aβ-induced toxicity, including morphological alterations, reactive oxygen species (ROS) production, a...		Autophagy
T78649	MAO-B-IN-4		Monoamine Oxidase
	MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM. This orally active compound exhibits favorable metabolic stability, a ...		Monoamine Oxidase
T22605	Bifemelane hydrochloride		MAO , Monoamine Oxidase
	Bifemelane hydrochloride is a MAO inhibitor		MAO , Monoamine Oxidase
T80634	MAO-B-IN-19		Monoamine Oxidase
	MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].		Monoamine Oxidase
T78648	MAO-B-IN-3		Monoamine Oxidase
	MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki of 696 nM, making it suitable for Alzheimer's disease resear...		Monoamine Oxidase
T72892	AChE/MAO-IN-1
	AChE/MAO-IN-1 is a potent inhibitor of human acetylcholinesterase (AChE), monoamine oxidase A (MAO-A), and monoamine oxidase B (MAO-B), demonstrating inhibitory concentrations (IC50) of 0.0248 μM, 0.0409 μM, and 0.1108 μ...
T62062	MAO-B-IN-7
	MAO-B-IN-7 is a potent and blood-brain barrier permeable MAO-B and AChE inhibitor. MAO-B-IN-7 exhibits IC50 s of 41 nM, 87 nM and 0.3 μM for human AChE, electric eel AChE and MAO-B, respectively. MAO-B-IN-7 effectively a...
T60660	MAO-B-IN-14
	MAO-B-IN-14 (Compound 9) is a potent and selective inhibitor of monoamine oxidase-B (MAO-B) with an IC 50 of 0.95 μM and a Ki of 0.55 μM for human MAO-B.
T64271	MAO-B-IN-6
	MAO-B-IN-6 is a selective, potent, orally active MAO-B inhibitor (IC50: 0.019 μM). MAO-B-IN-6 is superior to Safinamide both in vitro and in vivo.
T61131	MAO-B-IN-11
	MAO-B-IN-11, also known as Compound 8c, is a highly potent inhibitor of monoamine oxidase B (MAO-B), with an IC50 value of 1.3 μM. Additionally, MAO-B-IN-11 exhibits neuroprotective properties [1].
T60650	MAO-B-IN-13
	MAO-B-IN-13 (compound 12a) is a highly potent, reversible and blood-brain barrier (BBB) penetrant MAO-B inhibitor (IC50 = 10 nM). MAO-B-IN-13 shows neuroprotective and antioxidant activity which can be used in Parkinson’...
T78860	MAO-B-IN-24		Monoamine Oxidase
	MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 μM. It also exhibits inhibitory effects on MAO-A with an IC50 of 22.42 μM. At a concentration of 10 μM, MAO...		Monoamine Oxidase
T78859	MAO-B-IN-23		Monoamine Oxidase
	MAO-B-IN-23, also known as Compound 11f, is a reversible and competitive monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 1.44 μM and a Ki of 0.51 μM [1].		Monoamine Oxidase
T60573	MAO-B-IN-15
	MAO-B-IN-15 is a selective inhibitor of MAO-B that forms π-π interaction with Tyr 326 residue (IC 50 = 13.5 μM) which can be used in Parkinson’s disease research[1].
T74860	MAO-B-IN-21		Monoamine Oxidase
	MAO-B-IN-21 is an MAO-B inhibitor characterized by superior antioxidant and anti-Aβ aggregation activities. The compound additionally shows metal-ion chelating capabilities, mitigates neuroinflammation (NO, TNF-α), and d...		Monoamine Oxidase
T79761	MAO-B-IN-25		Monoamine Oxidase
	MAO-B-IN-25 (compound 92) is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting inhibitory half-maximal inhibitory concentrations (IC50) of 240 nM for MAO-B and 0.5 nM for MAO-A [1].		Monoamine Oxidase
T61321	MAO-B-IN-12
	MAO-B-IN-12 (Compound 16c) is a highly effective inhibitor of monoamine oxidase B (MAO-B), displaying significant potency with an IC50 value of 1.3 μM. Additionally, MAO-B-IN-12 exhibits notable neuroprotective activity ...
T72893	AChE/MAO-IN-2
	Dual AChE-MAO B-IN-5, an indanone derivative, serves as an effective dual inhibitor for AChE and MAO-B, displaying IC50 values of 0.0224 μM for AChE, 0.0412 μM for MAO-B, and 0.1116 μM for MAO-A. Additionally, it exhibit...
T61830	MAO-B-IN-10
	MAO-B-IN-10 (compound 4f) is a highly potent and selective inhibitor of MAO-B (monoamine oxidase-B). It effectively penetrates the blood-brain barrier and exhibits an IC50 of 5.3 μM. This compound demonstrates the abilit...
T81866	MAO-B-IN-27		Monoamine Oxidase
	MAO-B-IN-27 (Compound 12c), a monoamine oxidase B (MAO-B) inhibitor, exhibits a potent and selective inhibitory effect on hMAO-B, with an IC50 value of 8.9 nM, and is utilized in Parkinson's disease (PD) research [1].		Monoamine Oxidase
T78907	MAO-B-IN-22		Monoamine Oxidase
	MAO-B-IN-22 (compound 6h) represents a powerful MAO-B inhibitor, boasting an IC50 value of 0.014 μM, and exhibits high antioxidant activity alongside effective metal-chelating properties. It also demonstrates adequate BB...		Monoamine Oxidase
T72791	AChE/MAO-B-IN-3
	AChE/MAO-B-IN-3 is a dual inhibitor targeting both acetylcholinesterase (AChE) and monoamine oxidase B (MAO-B), exhibiting inhibitory concentrations (IC50s) of 0.0257 μM and 0.0456 μM against human AChE and MAO-B, respec...
T79486	MAO A/HSP90-IN-1		Monoamine Oxidase
	MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α. This compound impairs the activities of MAO A, disrupts HSP90...		Monoamine Oxidase
T79487	MAO A/HSP90-IN-2		Monoamine Oxidase
	MAO A/HSP90-IN-2 (compound 4-C), a dual inhibitor of HSP90 and MAO A, exhibits IC50 values of 0.016 μM for MAO A and 4.58 μM for HSP90. This compound not only enhances HSP70 expression but also diminishes HER2 and phosph...		Monoamine Oxidase
T60947	HDAC1/MAO-B-IN-1
	HDAC1/MAO-B-IN-1 has the potential to be used in the Alzheimer’s disease research. HDAC1/MAO-B-IN-1 is a potent and selective inhibitor of HDAC1/MAO-B that can cross the blood-brain barrier. The IC50 values of HDAC1/MAO-...
T61958	MAO A/HDAC-IN-1
	MAO A/HDAC-IN-1 is an effective monoamine oxidase A (MAO A) and HDAC dual inhibitor, which can be used for glioma research.
T6073	OG-L002		Histone Demethylase , Monoamine Oxidase , HSV
	OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.		Histone Demethylase , Monoamine Oxidase , HSV
T4559	Isocarboxazid		Monoamine Oxidase
	Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor.[2] It is used in the treatment of major depression, dysthymic disorder, atypical disor...		Monoamine Oxidase
T78679	AChE/BuChE/MAO-B-IN-2
	AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM, indicating good in vitro blood-brain barrier (BBB) permeability. It...
T62152	Dual AChE-MAO B-IN-2
	Dual AChE-MAO B-IN-2 is a potent, dual inhibitor of AChE (IC50: 0.12 μM) and MAO B (IC50: 0.01 μM).Dual AChE-MAO B-IN-2 has potential for Alzheimer's disease studies.
T72452	AChE/BChE/MAO-B-IN-2
	AChE/BChE/MAO-B-IN-2 is a potent inhibitor of the enzymes AChE, BChE, and MAO-B, with IC50 values of 48.2 nM, 83.9 nM, and 31.2 nM, respectively. It exhibits significant antioxidant activity and is applicable in Parkinso...
T62172	Dual AChE-MAO B-IN-1
	Dual AChE-MAO B-IN-1 (compound 15) is a safe, metabolically stable neuroprotective agent.Dual AChE-MAO B-IN-1 is a potent, orally active CNS-permeable inhibitor of human AChE (IC50=550 nM) and MAO-B (IC50=8.2 nM), and ha...
T74991	Dual AChE-MAO B-IN-3
	Dual AChE-MAO B-IN-3 (Compound C10) is a potent inhibitor of both AChE and MAO-B, exhibiting IC50 values of 0.58 μM and 0.41 μM, respectively. This dual-binding inhibitor targets the catalytic anionic site and peripheral...
T8849	PF-9601N		MAO
	PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.		MAO
T64036	5-HT6R/MAO-B modulator 1
	5-HT6R/MAO-B modulator 1 is an antagonist of 5-HT6R at Gs signaling and an irreversible inhibitor of MAO-B that exhibits glial protective activity. 5-HT6R/MAO-B modulator 1 exhibits induction of scopolamine-induced memor...

Compounds

MAO-IN-M30 dihydrochloride

T38034

Synonym: M 30 dihydrochloride

Target: Monoamine Oxidase

Target: Beta Amyloid, Serotonin Transporter, Monoamine Oxidase

Synonym: MAO-B Inhibitor-58

Target:

AChE/BChE/MAO-B-IN-1

Target: Monoamine Oxidase

MAO-B-IN-18

T78690

Synonym:

Target: Monoamine Oxidase

Target: Monoamine Oxidase

Bifemelane hydrochloride

T22605

Synonym:

Target: MAO, Monoamine Oxidase

MAO-B-IN-19

T80634

Synonym:

Target: Monoamine Oxidase

MAO-B-IN-3

T78648

Synonym:

Target: Monoamine Oxidase

Target: Monoamine Oxidase

MAO-B-IN-23

T78859

Synonym:

Target: Monoamine Oxidase

Target: Monoamine Oxidase

MAO-B-IN-25

T79761

Synonym:

Target: Monoamine Oxidase

Target: Monoamine Oxidase

MAO-B-IN-22

T78907

Synonym:

Target: Monoamine Oxidase

Target: Monoamine Oxidase

MAO A/HSP90-IN-2

T79487

Synonym:

Target: Monoamine Oxidase

Target: Histone Demethylase, Monoamine Oxidase, HSV

Isocarboxazid

T4559

Synonym:

Target: Monoamine Oxidase

AChE/BuChE/MAO-B-IN-2

T78679

Synonym:

Target:

Dual AChE-MAO B-IN-2

T62152

Synonym:

Target:

AChE/BChE/MAO-B-IN-2

T72452

Synonym:

Target:

Dual AChE-MAO B-IN-1

T62172

Synonym:

Target:

Dual AChE-MAO B-IN-3

5-HT6R/MAO-B modulator 1

T64036

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T3885	ROSIRIDIN	6'-O-Deacetylrosiridoside C,(-)-Rosiridin	Others , Monoamine Oxidase
	Rosiridin (6'-O-Deacetylrosiridoside C) has cardioprotective activity.		Others , Monoamine Oxidase
T2900	Paeonol	Peonol	MAO , Autophagy , Monoamine Oxidase
	Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.		MAO , Autophagy , Monoamine Oxidase
TN1120	Osthenol		MAO , Monoamine Oxidase
	Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promoting activity, it also has antifungal and antibacterial activ...		MAO , Monoamine Oxidase
T3152	Harmol	Methylpyridoindolol	Others
	Harmol (Methylpyridoindolol) is a β-carboline isolated from nature.		Others
T6862	Isatin	Pseudoisatin,Indoline-2,3-dione,2,3-Indolinedione	Apoptosis , MAO , Monoamine Oxidase
	Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor.		Apoptosis , MAO , Monoamine Oxidase
T2765	Rosmarinic acid	Labiatenic acid,Rosemary acid	Apoptosis , IκB/IKK , MAO , Endogenous Metabolite , Transferase , Monoamine Oxidase
	Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities. It inhibits MAO-A, MAO-B, and COMT with IC50 of 50.1, 184.6, and 26.7 μM respectively.
T5S0734	Desmethoxyyangonin	Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain	Others , Monoamine Oxidase
	1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydr...		Others , Monoamine Oxidase
TN2004	Obtusin		MAO , Monoamine Oxidase
	Obtusin is a natural product.		MAO , Monoamine Oxidase
T3158	Harmane	Loturine,Harman,Aribine	Adrenergic Receptor , Monoamine Oxidase , Imidazoline Receptor
	Harmane (Loturine) is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee and tobacco smoke.
T4024	Norharmane	2-Azacarbazole,2,9-Diazafluorene,β-Carboline	DNA , Endogenous Metabolite , Monoamine Oxidase
	Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family.		DNA , Endogenous Metabolite , Monoamine Oxidase
T13475	β-Aminopropionitrile	3-Aminopropionitrile,BAPN	Others , Endogenous Metabolite
	β-Aminopropionitrile (3-Aminopropionitrile) is a selective inhibitor of lysyl oxidase.		Others , Endogenous Metabolite
T6S0923	Hypericin	Hypericine,Cyclosan	Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC
	1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL...
TN2081	Maohuoside A		MAPK
	Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.		MAPK
TN4494	Maoecrystal B		Others
	Maoecrystal B is a diterpenoid isolated from the leaves of Isodon eriocalyx var.		Others
TN4495	Maoyerabdosin		Others
	Maoyerabdosin is a kind of natural product derived from the herbs of Isodon.		Others
T4S1980	Maoecrystal A		Others
	Maoecrystal A is a natural compound isolated from the leaves of I. eriocalyx.		Others
T72798	Ganodermaones B
	Ganodermaones B is a renal fibrosis inhibitor. Ganodermaones B inhibits TGF-β1-induced collagen I and fibronectin expression .
TN7057	Rosmarinate acid	(R)-rosmarinic acid,rosmarinic acid,Rosemary acid	MAO , Endogenous Metabolite , Transferase
	Rosmarinate acid(Rosemary acid) inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively		MAO , Endogenous Metabolite , Transferase
T3933	Jatrorrhizine	Yatrorizine,neprotin	MAO , 5-HT Receptor , Antibacterial , AChE
	Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo...		MAO , 5-HT Receptor , Antibacterial , AChE
T10146	4-Hydroxyderricin		Dehydrogenase , MAO
	4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-hydroxylase (DBH) activity and possesses antidepressant acti...		Dehydrogenase , MAO
T5648	Purpurin	1,2,4-Trihydroxyanthraquinone,Hydroxylizaric acid,Verantin	MAO , Antibacterial , Antibiotic , Antifungal
	Purpurin (Verantin) was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422μM. it exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities.		MAO , Antibacterial , Antibiotic , Antifungal
T4590	(+)-Kavain	Kavain,L-KAWAIN,(R)-KAWAIN	Calcium Channel , GABA Receptor , Sodium Channel , Monoamine Transporter
	(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
T1311	4-aminobenzoic acid	PABA,Vitamin H1,Vitamin Bx,para-Aminobenzoic acid	Endogenous Metabolite
	4-aminobenzoic acid (para-Aminobenzoic acid) is an organic acid with UV absorption and antifibrotic properties. When exposed to light, 4-aminobenzoic acid absorbs UV light and emits excess energy via a photochemical reac...		Endogenous Metabolite
T3822	Bellidifolin	Bellidifoline,Bellidifolium	Others , HIV Protease
	Bellidifolin (Bellidifoline) has anti-oxidation, hepatoprotective, anti-inflammatory and antitumor actions, it may contribute to the protective effects associated with nerve injury initiated by hypoxia by mechanisms rela...		Others , HIV Protease
T2741	Glycyrrhizic acid	Glycyrrhizin	Virus Protease , Dehydrogenase , MAO
	Glycyrrhizic acid (Glycyrrhizin) is a triterpenoid saponinl with anti-tumor and anti-diabetic activities.		Virus Protease , Dehydrogenase , MAO
T0966	Sennoside A	NSC 112929	MAO , HIV Protease
	Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.		MAO , HIV Protease
TN1470	Cassiaside B2		Phosphatase , MAO , 5-HT Receptor
	Cassiaside B2 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A).Cassiaside B2 is an agonist of the 5-HT2C receptor with anti-allergic activity.Cassiaside B2 is one of the a...		Phosphatase , MAO , 5-HT Receptor
T1711	Harmine	Telepathine	MAO , 5-HT Receptor , DYRK
	Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.		MAO , 5-HT Receptor , DYRK
TN2553	1-Methyl-2-undecyl-4(1H)-quinolone	1-Methyl-2-undecylquinolin-4(1H)-one	MAO
	1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinol...		MAO
T40244	Methyl citrate
	Methyl citrate, obtained from Opuntia ficus-indica var. saboten Makino fruits, serves as a potent Monoamine oxidase B (MAO-B) inhibitor with an IC50 value of 0.23 mM.
TN3294	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate		NADPH-oxidase , P450 , MAO
	8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes.		NADPH-oxidase , P450 , MAO
T79979	Methyl piperate		Monoamine Oxidase
	Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibition of MAO-A (IC 50 27.1 μM) compared to MAO-B (IC 50 1.6 μM), ...		Monoamine Oxidase
TN1099	Dihydroevocarpine		MAO , P-gp , Antifection
	Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a moderate modulator of p-glycoprotein (p-gp) activity; it s...		MAO , P-gp , Antifection
TN3300	8alpha-Tigloyloxyhirsutinolide 13-O-acetate		NADPH-oxidase , P450 , MAO
	8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has anti-cancer activity, it is active against both cancer cell...		NADPH-oxidase , P450 , MAO
TN3726	Cudraflavone B		IκB/IKK , MAO , ROS , Akt , COX , PI3K , Nrf2 , Autophagy
	Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mouse melanoma cells, and hepatoprotective activity. It may b...		IκB/IKK , MAO , ROS , Akt , COX , PI3K , Nrf2 , Autophagy
TN1724	Harmalol hydrochloride	Harmidol hydrochloride	P450 , Antioxidant
	Harmalol hydrochloride (Harmidol hydrochloride) is a β-carboline alkaloid that can be extracted from the seeds of Peganum harmala L. Harmalol hydrochloride is the major metabolite of Harmaline and significantly inhibits ...		P450 , Antioxidant
T40576	(S)-Salsolidine
	(S)-Salsolidine, a chemical compound, functions as a weak inhibitor of monoamine oxidase (MAO), exhibiting an inhibition constant (K i ) of 63 μM. R enantiomer demonstrating a greater efficacy than (S)-Salsolidine, boast...
TN4137	Glicoricone		MAO
	Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.		MAO
T40628	Chrysophanol-1-O-β-gentiobioside
	Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside obtained from the seeds of Cassia obtusifolia, exhibits targeted inhibition of hMAO-A isozyme activity with an IC50 value of 96.15 μM.
T36950	Rubrofusarin triglucoside
	Rubrofusarin triglucoside, a glycoside isolated from Cassia obtusifolia Linn seeds, demonstrates inhibitory activity against human monoamine oxidase A (hMAO-A), exhibiting an IC50 value of 85.5 μM[1].

Natural Products

ROSIRIDIN

T3885

Synonym: 6'-O-Deacetylrosiridoside C,(-)-Rosiridin

Target: Others, Monoamine Oxidase

Paeonol

T2900

Synonym: Peonol

Target: MAO, Autophagy, Monoamine Oxidase

Osthenol

TN1120

Synonym:

Target: MAO, Monoamine Oxidase

Harmol

T3152

Synonym: Methylpyridoindolol

Target: Others

Isatin

T6862

Synonym: Pseudoisatin,Indoline-2,3-dione,2,3-Indolinedione

Target: Apoptosis, MAO, Monoamine Oxidase

Rosmarinic acid

T2765

Synonym: Labiatenic acid,Rosemary acid

Target: Apoptosis, IκB/IKK, MAO, Endogenous Metabolite, Transferase, Monoamine Oxidase

Desmethoxyyangonin

T5S0734

Synonym: Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain

Target: Others, Monoamine Oxidase

Obtusin

TN2004

Synonym:

Target: MAO, Monoamine Oxidase

Harmane

T3158

Synonym: Loturine,Harman,Aribine

Target: Adrenergic Receptor, Monoamine Oxidase, Imidazoline Receptor

Norharmane

T4024

Synonym: 2-Azacarbazole,2,9-Diazafluorene,β-Carboline

Target: DNA, Endogenous Metabolite, Monoamine Oxidase

β-Aminopropionitrile

T13475

Synonym: 3-Aminopropionitrile,BAPN

Target: Others, Endogenous Metabolite

Hypericin

T6S0923

Synonym: Hypericine,Cyclosan

Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC

Synonym: (R)-rosmarinic acid,rosmarinic acid,Rosemary acid

Target: MAO, Endogenous Metabolite, Transferase

Jatrorrhizine

T3933

Synonym: Yatrorizine,neprotin

Target: MAO, 5-HT Receptor, Antibacterial, AChE

4-Hydroxyderricin

T10146

Synonym:

Target: Dehydrogenase, MAO

Purpurin

T5648

Synonym: 1,2,4-Trihydroxyanthraquinone,Hydroxylizaric acid,Verantin

Target: MAO, Antibacterial, Antibiotic, Antifungal

(+)-Kavain

T4590

Synonym: Kavain,L-KAWAIN,(R)-KAWAIN

Target: Calcium Channel, GABA Receptor, Sodium Channel, Monoamine Transporter

4-aminobenzoic acid

T1311

Synonym: PABA,Vitamin H1,Vitamin Bx,para-Aminobenzoic acid

Target: Endogenous Metabolite

Bellidifolin

T3822

Synonym: Bellidifoline,Bellidifolium

Target: Others, HIV Protease

Glycyrrhizic acid

T2741

Synonym: Glycyrrhizin

Target: Virus Protease, Dehydrogenase, MAO

Sennoside A

T0966

Synonym: NSC 112929

Target: MAO, HIV Protease

Cassiaside B2

TN1470

Synonym:

Target: Phosphatase, MAO, 5-HT Receptor

Harmine

T1711

Synonym: Telepathine

Target: MAO, 5-HT Receptor, DYRK

1-Methyl-2-undecyl-4(1H)-quinolone

TN2553

Synonym: 1-Methyl-2-undecylquinolin-4(1H)-one

8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate

TN3294

Synonym:

Target: NADPH-oxidase, P450, MAO

Methyl piperate

T79979

Synonym:

Target: Monoamine Oxidase

Dihydroevocarpine

TN1099

Synonym:

Target: MAO, P-gp, Antifection

8alpha-Tigloyloxyhirsutinolide 13-O-acetate

TN3300

Synonym:

Target: NADPH-oxidase, P450, MAO

Cudraflavone B

TN3726

Synonym:

Target: IκB/IKK, MAO, ROS, Akt, COX, PI3K, Nrf2, Autophagy

Harmalol hydrochloride

TN1724

Synonym: Harmidol hydrochloride

Target: P450, Antioxidant

Chrysophanol-1-O-β-gentiobioside

T40628

Synonym:

Target:

Rubrofusarin triglucoside

T36950

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-05918	Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019)/(A/Hawaii/70/2019) Hemagglutinin/HA Protein (His)	H1N1	HEK293
	The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two...
TMPY-06059	Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019) Nucleoprotein/NP Protein (His)	H1N1	Baculovirus-Insect Cells
	Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter...
TMPH-00683	TMAO reductase 1 Protein, E. coli O157:H7, Recombinant (His & Myc)	E. coli	E. coli
	Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.
TMPY-06887	Influenza A H1N1 (A/Hawaii/70/2019;A/Guangdong-Maonan/SWL1536/2019) Hemagglutinin/HA Protein (His)	H1N1	Baculovirus-Insect Cells
	The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two...
TMPH-00926	MAOB Protein, Human, Recombinant (His)	Human	E. coli
	MAOB Protein, Human, Recombinant (His) is expressed in E. coli.

Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019)/(A/Hawaii/70/2019) Hemagglutinin/HA Protein (His)

TMPY-05918

Species: H1N1

Expression System: HEK293

Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019) Nucleoprotein/NP Protein (His)

TMPY-06059

Species: H1N1

Expression System: Baculovirus-Insect Cells

TMAO reductase 1 Protein, E. coli O157:H7, Recombinant (His & Myc)

TMPH-00683

Species: E. coli

Expression System: E. coli

Influenza A H1N1 (A/Hawaii/70/2019;A/Guangdong-Maonan/SWL1536/2019) Hemagglutinin/HA Protein (His)

TMPY-06887

Species: H1N1

Expression System: Baculovirus-Insect Cells

MAOB Protein, Human, Recombinant (His)

TMPH-00926

Species: Human

Expression System: E. coli

Cat No.	Product Name
L9830	Anti-Parkinson's Disease Compound Library		908 compounds
	A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.

Libraries

Anti-Parkinson's Disease Compound Library

L9830

Compounds: 908