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Cat No. | Product Name | Synonyms | Targets |
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T13015 | STING agonist-4 | STING | |
STING agonist-4 is an agonist of stimulator of Interferon Genes (STING) receptor(IC50 of 20 nM). | |||
T13613 | ChX710 | STING | |
ChX710 activates the type I interferon response to cytosolic DNA by priming specific Interferon-Stimulated Genes (ISGs), inducing the ISRE promoter sequence, and facilitating the phosphorylation of Interferon Regulatory ... | |||
T7329 | C-178 | STING | |
C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells. | |||
T9853 | STING activator Compound 53 | STING | |
STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint cons... | |||
T6919 | Omaveloxolone | RTA-408 | Apoptosis , Others , Nrf2 , STING |
Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2. | |||
T9554 | SN-008 | STING | |
SN-008 is a less active analog SN-011 which is a STING antagonist. SN-008 can be used as a negative control. | |||
T5674 | H-151 | STING | |
H-151 is a highly potent and selective STING antagonist. H-151 covalently binds to Cys91 of STING and inhibits palmitoylation of Cys91, thereby inhibiting STING activity. H-151 can be used in the study of autoinflammator... | |||
T8655 | SR-717 | STING | |
SR-717 is a cGAMP analog, a non-nucleoside STING agonist that induces a "closed" activation conformation of STING. SR-717 has antitumor activity and promotes activation of immune cells and cross-presentation of antigens. | |||
T9029 | STING-IN-3 | C-171 | STING |
STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. | |||
T8798 | MSA-2 | STING | |
MSA-2 is a potent and orally available non-nucleotide STING agonist. | |||
T5516 | DiABZI STING agonist-1 trihydrochloride | STING | |
diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist. | |||
T5154 | C-176 | C176,STING inhibitor 1 | STING |
C-176 (STING inhibitor 1) is a strong, covalent mouse STING inhibitor | |||
T8328 | STING agonist-1 | G10 | Virus Protease , STING |
STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses. | |||
T9028 | STING-IN-2 | C-170 | STING |
STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research. | |||
T7081 | CCCP | Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone | Apoptosis , IκB/IKK , COX , Mitochondrial Metabolism , STING , IFNAR , Antibacterial |
CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the activation of STING and its downstream signaling molecules ... | |||
T9137 | SN-011 | [1,1'-Biphenyl]-4-carboxamide, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-,GUN35901 | STING |
SN-011 (GUN35901) is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING- mediated disease. It is a demethyl analogue of DUN99845. | |||
T10252L2 | ADU-S100 ammonium salt | ML RR-S2 CDA ammonium salt,MIW815 ammonium salt | STING |
ADU-S100 ammonium salt (ML RR-S2 CDA ammonium salt) is an activator of stimulator of interferon genes (STING). ADU-S100 ammonium salt leads to potent and systemic tumor regression and immunity. | |||
T6273 | Vadimezan | DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404 | Influenza Virus , VDA , STING , IFNAR |
Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and induces a rapid cessation of blood flow in tumors without aff... | |||
T15102 | Dexamethasone palmitate | DXP | Glucocorticoid Receptor |
Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone, shows a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone. Dexamethasone palmitate is a glucocorticoid receptor agonist and an... | |||
T77748 | Tusamitamab | Others | |
Tusamitamab is an IgG1 monoclonal antibody targeting CEACAM5 and is the naked antibody to Tusamitamab ravtansine.Tusamitamab can be used to synthesize the antibody-activator coupling Tusamitamab ravtansine. | |||
T6267 | Lomitapide | AEGR-733,BMS-201038 | CETP |
Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring... | |||
T0752 | Ascorbyl palmitate | L-Ascorbic acid 6-hexadecanoate,6-O-Palmitoyl-L-ascorbic acid,L-Ascorbyl 6-palmitate | Reactive Oxygen Species , Endogenous Metabolite |
Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate), an ester formed from ascorbic acid and palmitic acid, produces a fat-soluble form of vitamin C. | |||
T2545 | Lomitapide Mesylate | BMS-201038 mesylate,AEGR-733 mesylate | CETP |
Lomitapide Mesylate (BMS-201038 mesylate) is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein. | |||
T9183 | Ralmitaront | RO6889450 | Others |
Ralmitaront (RO6889450) is a potent, orally active partial agonist of the trace amine-associated receptor 1 (TAAR1). | |||
T3282 | Alimemazine hemitartrate | Alimemazine Tartrate,Methylpromazine Tartrate,Trimeprazine tartrate,Trimeprazine hemitartrate | Others |
Alimemazine hemitartrate (Trimeprazine hemitartrate) is aphenothiazine derivative that is used as an antipruritic. It also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness. | |||
T9409 | Mesdopetam hemitartrate | IRL790 hemitartrate,1-Propanamine, N-[2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1) | Dopamine Receptor |
Mesdopetam hemitartrate (IRL790 hemitartrate) is an antagonist of dopamine D3 receptor (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor). It has psychomotor stabilizing properties. | |||
T2259 | Silmitasertib | CX-4945 | Casein Kinase , Autophagy |
Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM). | |||
T15024 | Silmitasertib sodium salt | CX-4945 sodium salt | Casein Kinase , Autophagy |
Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α). | |||
T11176 | Eliglustat hemitartrate | Genz-112638,Eliglustat tartrate | Others |
Eliglustat hemitartrate (Genz-112638) , with an IC50 of 24 nM, is a specific, potent, oral active glucocerebral glycosidase inhibitor. | |||
T4223 | Mitapivat | PKR-IN-1 | PKM |
Mitapivat (PKR-IN-1), also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency. | |||
T20525 | Chloramphenicol palmitate | Antibacterial , Antibiotic | |
Chloramphenicol palmitate is a broad-spectrum antibiotic with activity against gram-positive and gram-negative bacteria. Chloramphenicol palmitate can be used in studies about acting as a bacterial selection agent in tra... | |||
T66561 | 2-Chloroethyl palmitate | ||
2-Chloroethyl palmitate is a useful organic compound for research related to life sciences. The catalog number is T66561 and the CAS number is 929-16-8. | |||
T39513 | Ladostigil hemitartrate | TV-3326 hemitartrate,Ladostigil hemitartrate | |
Ladostigil hemitartrate (TV-3326) is a compound that acts as a dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO). It has IC50 values of 37.1 μM for MAO-B and 31.8 μM for AChE. In addition, Lado... | |||
T77090 | Mitazalimab | ||
Mitazalimab (ADC-1013; JNJ-64457107) is an FcγR-dependent CD40 agonist that exhibits directed activity against tumors. By activating antigen-presenting cells, such as dendritic cells (DC), it triggers the initiation of t... | |||
T6449 | Clindamycin palmitate hydrochloride | Cleocin Pediatric,Clindamycin palmitate HCl | Antibacterial , Antibiotic |
Clindamycin palmitate hydrochloride (Clindamycin palmitate HCl) is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic. | |||
T77905 | Vobramitamab | AEX-4089 | |
Vobramitamab, a humanized B7-H3 monoclonal antibody (mAb), is conjugated to the prodrug seco-DUBA through a cleavable linker, creating the antibody-drug conjugate (ADC) known as MGC018 [1]. | |||
T32123 | Hydroxyproline palmitamide | N-Palmitoylhydroxyproline | |
Hydroxyproline palmitamide is a bioactive chemical. | |||
T66371 | 2-Hydroxyethyl palmitate | ||
2-Hydroxyethyl palmitate is a useful organic compound for research related to life sciences. The catalog number is T66371 and the CAS number is 4219-49-2. | |||
T69677 | Mitapivat sulfate anhydrous | ||
Mitapivat sulfate anhydrous is an allosteric activator of Pyruvate Kinase (PK) that may be useful in the treatment of Pyruvate Kinase Deficiency. | |||
T74588 | Yimitasvir diphosphate | ||
Yimitasvir (Emitasvir) diphosphate is an orally administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A), utilized in the research of chronic hepatitis C virus infection [1]. | |||
T78669 | (1R,4S)-Yimitasvir diphosphate | (1R,4S)-DAG-181 diphosphate,(1R,4S)-Emitasvir diphosphate | |
Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A). It is utilized in the study of chronic hepatitis C virus infections [1]... | |||
T77907 | Tusamitamab ravtansine | HuMAb2-3-SPDB-DM4,SAR-408701 | |
Tusamitamab ravtansine (SAR-408701) is a DM4-linked anti-CEACAM5 antibody-drug conjugate (ADC) comprising a humanized monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) conj... | |||
T74589 | Yimitasvir | ||
Yimitasvir (Emitasvir), an orally administered inhibitor targeting the hepatitis C virus's (HCV) nonstructural protein 5A (NS5A), shows potential for the exploration of chronic HCV infection treatments [1]. | |||
T71441 | Glutathione palmitamide | ||
Glutathione palmitamide is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth. | |||
T68642 | Kahweol palmitate | ||
Kahweol palmitate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducin... | |||
T23457 | Threo Ifenprodil hemitartrate | Others | |
σ receptor agonist and NR2B subunit-selective NMDA receptor antagonist | |||
T83314 | 4-Methylumbelliferyl palmitate | ||
4-Methylumbelliferyl palmitate serves as a potent fluorophore to assay acid lipase activity in human leukocytes, with its fluorescence significantly affected by acidity and solvent properties. In near-neutral aqueous sol... | |||
T66616 | (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-palmitamidohexanoic acid | ||
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-palmitamidohexanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66616 and the CAS number is 201004-46-8. | |||
T81594 | Osemitamab | TST001 | |
Osemitamab, an IgG1 antibody, targets human claudin-18.2 and comprises a human-Mus musculus monoclonal TST001 γ1-chain disulfide-bonded to a human-Mus musculus monoclonal TST001 κ-chain dimer (ACI). It is utilized, in co... | |||
T41182 | Ifenprodil hemitartrate | ||
Ifenprodil hemitartrate is a NMDA receptor antagonist, acting at the polyamine site. Also anα-adrenergic vasodilator.σ2ligand displaying about 3-fold selectivity overσ1sites. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1059 | Retinyl palmitate | Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate | Others , Endogenous Metabolite |
Retinyl palmitate (Vitamin A palmitate) is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities. | |||
T12139 | N-(3-Methoxybenzyl)Palmitamide | FAAH | |
N-(3-Methoxybenzyl)Palmitamide is a promising FAAH inhibitor, treatment of pain, inflammation and CNS degenerative disorders. | |||
T2S0164 | Ethyl palmitate | Palmitic acid ethyl ester,Ethyl cetylate,Ethyl hexadecanoate | Others |
Ethyl palmate (palmitic acid ethyl ester) is a type of fatty acid ethyl ester (FAEE). After human subjects consumed alcohol, its synthesis was higher than other FAEEs. It can be used as a hair and skin conditioner. | |||
TWO2727 | Propane-1,2,3-triyl tripalmitate | Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate | Others , Endogenous Metabolite |
Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) is a triacylglycerol found in dietary fats. Tripalmitin increases body weight and plasma LDL levels and reduces hepatic LDL receptor mRNA levels in hamsters fed a ... | |||
TN1107 | Lupeol palmitate | Others | |
Lupeol palmitate is a naturally occurring compound that can be extracted from Ligularia songarica and has antiulcer activity and gastrointestinal protection. | |||
T2S0157 | Methyl palmitate | Methyl hexadecanoate,Palmitic acid methyl ester | Others |
Methyl palmitate (Palmitic acid methyl ester) is used as an intermediate of emulsifier, wetting agent, stabilizer and plasticizer. | |||
T5074 | Cholesteryl palmitate | Others , Endogenous Metabolite | |
Cholesteryl palmitic acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a ... | |||
T3S2105 | N-Benzylpalmitamide | Macamide 1,N-Benzylhexadecanamide | Others , FAAH , Autophagy |
N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the treatment of pain, inflammation and CNS degenerative disorders... | |||
T20006 | Isopropyl palmitate | EINECS 205-571-1,Isopropyl hexadecanoate,BRN 1786567,AI3-05733,Emcol-IP,HSDB 2647 | |
Isopropyl palmitate is the isopropyl alcohol and palmitic acid ester. It is a moisturizer, emollient, anti-static agent, and thickening agent. | |||
T83450 | 14-Benzoylmesaconine-8-palmitate | ||
Compound 4, 14-Benzoylmesaconine-8-palmitate, is a lipo-alkaloid that can be isolated from A. toxicum [1]. | |||
TN3510 | Betulin palmitate | Others | |
Betulin palmitate is a natural product for research related to life sciences. The catalog number is TN3510 and the CAS number is 582315-55-7. | |||
T40424 | 9-cis-Vitamin A palmitate | 9-cis-Vitamin A palmitate,9-cis-Retinyl palmitate | |
9-cis-Vitamin A palmitate (9-cis-Retinyl palmitate) is a 9-cis isomer resulting from the interaction of vitamin A palmitate in corn flakes. It exhibits a biological activity of 26% compared to all-trans-vitamin A palmita... | |||
TN5987 | Betulinic acid palmitate | ||
Betulinic acid palmitate is a natural product for research related to life sciences. The catalog number is TN5987 and the CAS number is 19833-15-9. | |||
TN3383 | α-Amyrin palmitate | alpha-Amyrin palmitate | PKA |
alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats. alpha-Amyrin palmitate is a potent non-competitive inhibitor of chymotrypsin (Ki=6 microM), it also shows weak cytotoxicity against the ... | |||
T75679 | 13-cis-Vitamin A palmitate | ||
13-cis-Vitamin A palmitate (13-cis-Retinyl palmitate), a derivative of vitamin A palmitate found in corn flakes, is the 13-cis isomer exhibiting 75% of the biological activity of all-trans-vitamin A palmitate, which is t... | |||
TN4011 | Erythrodiol 3-palmitate | Others | |
Erythrodiol 3-palmitate has antitumor activity, it inhibited the proliferation of K562 cells with the inhibition rate of 47% at 100 ug/mL. | |||
TN4253 | Ingenol 3-palmitate | Others | |
Ingenol-3-palmitate shows irritant and cocarcinogenic activity on mouse ear and on mice back skin. | |||
T81395 | Progenin III palmitate | ||
Progenin III palmitate, a steroid glycoside ester, is isolated from the rhizomes of Dioscorea cayenensis [1]. | |||
T75425 | Synephrine hemitartrate | ||
Synephrine hemitartrate (Oxedrine), an alkaloid extracted from Citrus aurantium, functions as both an α-adrenergic and β-adrenergic agonist. As a sympathomimetic compound, it has applications in weight loss [1] [2]. | |||
TN4773 | Zeaxanthin dipalmitate | Physalien | Others |
Zeaxanthin dipalmitate is a natural product for research related to life sciences. The catalog number is TN4773 and the CAS number is 144-67-2. | |||
TN4252 | Ingenol 20-palmitate | Others | |
Ingenol 20-palmitate is a natural product from Euphorbia sieboldiana. | |||
TN2590 | 11alpha,12alpha-Oxidotaraxerol palmitate | Others | |
11alpha,12alpha-Oxidotaraxerol palmitate shows selective cytotoxicity against HCT-8, Bel-7402, BGC-823, A549 and A2780. | |||
TN5032 | Sitosteryl palmitate | Others | |
Sitosteryl palmitate is a natural product of Astilbe, Saxifragaceae. The catalog number is TN5032 and the CAS number is 2308-85-2. Sitosteryl palmitate can be used as a reference standard. |
Cat No. | Product Name | Species | Expression System |
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TMPH-00037 | Leukotoxin Protein, Aggregatibacter actinomycetemcomitans, Recombinant (His) | Aggregatibacter actinomycetemcomitans | Yeast |
Virulence factor that plays an important role in immune evasion. Lyses human lymphocytes and monocytes. Binds to the LFA-1 integrin on the surface of the host cell and to cholesterol-containing membranes, which probably ... |