T7030 |
Anemarsaponin B
|
|
p38 MAPK
,
NF-κB
,
MEK
,
COX
,
NO Synthase
|
|
Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhi... |
TP1313L |
Cecropin B acetate
|
Cecropin B acetate(80451-05-4 Free base) |
P450
,
Retinoid Receptor
,
Parasite
|
|
Cecropin B acetate induces NF-κB activation and suppresses CYP3A29 by disrupting the association of the PXR/retinoid X r... |
T6429 |
Caffeic Acid Phenethyl Ester
|
CAPE , Phenylethyl Caffeate |
NF-κB
,
Apoptosis
|
|
Caffeic Acid Phenethyl Ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress ... |
T0798 |
Triamcinolone
|
Fluoxyprednisolone , Rodinolone , Aristocort |
Glucocorticoid Receptor
,
COX
|
|
Triamcinolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, tr... |
T39924 |
NF-κΒ activator 2
|
|
NF-κB
|
|
NF-κΒ activator 2 is a potent and orally active NF-κB activator, with an EC 50 of 1.58 μM. NF-κΒ activator 2 induces SOD... |
T23872 |
Cellocidin
|
NSC#65381 , NSC65381 , NSC-65381 , NSC# 65381 , NSC 65381 |
|
|
Cellocidin is a potent gammaherpesvirus-associated B-lymphomas growth inhibitor. It acts through the activation of both ... |
T24548 |
NSC10010
|
NSC 10010 , NSC#10010 , NSC# 10010 , NSC-10010 , NSC#-10010 |
|
|
NSC10010 is an effective growth inhibitor for gammaherpesvirus-associated B-lymphomas. It acts through activation of bot... |
TN4490 |
Manassantin B
|
|
BCL
,
ERK
,
NF-κB
,
TNF
,
p38 MAPK
,
Antifection
,
STAT
,
JNK
|
|
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subun... |
T25050 |
Alloferon 3
|
|
|
|
Alloferon 3 is a natural peptide that mediates signaling by the NF-kappa B pathway to enhance the recognition of viral a... |
TN4652 |
Niazimicin
|
|
NF-κB
,
PI3K
,
AChR
,
Antifection
|
|
Niazimicin are NF-B and PI3K inhibitors, which shows antimicrobial, hypotensive and spasmolytic activities. Niazimicin h... |
T61885 |
Sulconazole
|
|
|
|
Sulconazole is an imidazole compound with effective antifungal effect. Sulconazole vs. NF- κ B/IL-8 signal pathway has b... |
T36169 |
15-LOX-1 inhibitor 1
|
|
|
|
9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1; IC50 = 0.19 μM).1 It decreases LPS- and IFN-γ-induced NF- B acti... |
T37644 |
Bengamide B
|
|
|
|
Potent inhibitor of NF-κB activation (IC50 = 85 nM); decreases IκBα phosphorylation. Attenuates LPS-induced nitric oxide... |
T28065 |
ML263
|
ML-263 , ML 263 |
|
|
ML263 inhibits NF-kB activation induced by B-cell specific antigen receptor. |
T3893 |
Forsythoside B
|
|
TNF
,
NF-κB
|
|
Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythosid... |
T27033 |
CKD-712
|
CKD 712 , CKD712 |
|
|
CKD-712 is a nuclear factor NF-kappa B inhibitor. CKD-712 suppressed MMP-9, but not MMP-2 and other NF-κB-regulated prot... |
T13265 |
Urolithin B
|
|
NF-κB
,
ERK
,
Akt
,
Endogenous Metabolite
,
JNK
,
AMPK
|
|
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pome... |
T6823 |
E3330
|
|
DNA/RNA Synthesis
,
HIF/HIF Prolyl-Hydroxylase
|
|
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity. |
T70595 |
Artemisinin B
|
|
|
|
Artemisinin B is a drug which may improve spatial memory in dementia patients and alter the levels of inflammatory cytok... |
T71925 |
Isonanangenine B
|
|
|
|
Isonanangenine B is a drimane sesquiterpene lactone that has been found in Aspergillus. It decreases survivin mRNA expre... |