Search Result

Search Results for " nf-��b "

Libraries

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Compounds

Cat No.	Product Name
T39924	NF-κΒ activator 2		NF-κB
	NF-κΒ activator 2 is a potent and orally active NF-κB activator, with an EC 50 of 1.58 μM. NF-κΒ activator 2 induces SOD...		NF-κB
T3893	Forsythoside B		NF-κB , TNF
	Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythosid...		NF-κB , TNF
T6S0781	Phellodendrine	Phallodendrin	NF-κB , Akt , Others
	1. Phellodendrine has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration o...		NF-κB , Akt , Others
T8705	BOT-64		IκB/IKK
	BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-...		IκB/IKK
T7030	Anemarsaponin B		MEK , NF-κB , NO Synthase , p38 MAPK , COX
	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhi...		MEK , NF-κB , NO Synthase , p38 MAPK , COX
T9105	NF-κB-IN-1	1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-	IκB/IKK , NF-κB
	NF-κB-IN-1 is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 directly inh...		IκB/IKK , NF-κB
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pome...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T0708	Oxaprozin	Oxaprozinum,Wy21743	COX , NF-κB
	Oxaprozin is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibito...		COX , NF-κB
TD0099	Malachite green oxalate		Others , NF-κB , IκB/IKK , Apoptosis
	Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reac...		Others , NF-κB , IκB/IKK , Apoptosis
T2872	Ginsenoside Re	Sanchinoside Re,Ginsenoside B2,Chikusetsusaponin Ivc,Panaxoside Re	NF-κB , Beta Amyloid , Endogenous Metabolite , JNK
	Ginsenoside Re may have properties that inhibit or prevent the growth of tumors.		NF-κB , Beta Amyloid , Endogenous Metabolite , JNK
T3826	Polygalasaponin F		TLR , NF-κB , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO in...		TLR , NF-κB , Akt , PI3K
T4S21320	ISOGINKGETIN	4',4'''-Dimethylamentoflavone	Others , MMP
	1. Isoginkgetin, a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency ...		Others , MMP
T2279	Tizoxanide	Desacetyl-nitazoxanide,TIZ	HIV Protease , Autophagy , Antiviral , Antibacterial
	Desacetyl-nitazoxanide is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) i...		HIV Protease , Autophagy , Antiviral , Antibacterial
T3417	Amentoflavone	3',8''-Biapigenin,Amenthoflavone,Didemethyl-ginkgetin	Apoptosis , COX , Opioid Receptor , Reactive Oxygen Species , RSV , Phospholipase , Antifungal , P450 , Antibacterial
	Amentoflavone, as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 a...
T25465	GS143	GS 143,GS-143	NF-κB , E1/E2/E3 Enzyme , IκB/IKK
	GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. G...		NF-κB , E1/E2/E3 Enzyme , IκB/IKK
TP1313L	Cecropin B acetate	Cecropin B acetate(80451-05-4 Free base)	P450 , Parasite , Retinoid Receptor
	Cecropin B acetate induces NF-κB activation and suppresses CYP3A29 by disrupting the association of the PXR/retinoid X r...		P450 , Parasite , Retinoid Receptor
T6823	E3330		HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
	E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.		HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
T3772	Maslinic acid	Crategolic acid,2α-Hydroxyoleanoic Acid,2α-Hydroxyoleanolic acid	HIV Protease , NF-κB , DNA/RNA Synthesis , Antibacterial
	Maslinic acid is a DNA polymerase B inhibitor.		HIV Protease , NF-κB , DNA/RNA Synthesis , Antibacterial
T11096	DRI-C21045		NF-κB
	Dri-c21045 showed concentration-dependent inhibition of NF- B activation and all CD40L induced by B cell proliferation. ...		NF-κB
T7302	CU-CPT9b	TLR8-specific antagonist 1,CU-CPT-9b	TLR
	CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF- B induced by the TLR...		TLR