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Search Results for "nf-kb��"

Libraries

NF-κB Signaling Compound Library Cytokine Inhibitor Library Immunology/Inflammation Compound Library

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Compounds

Cat No.	Product Name
TP1615L	IKKγ NBD Inhibitory Peptide acetate	IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base)	NF-κB
	IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO ami...		NF-κB
T3S1692	Octahydrocurcumin		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
	Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-indu...		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
TN6730	Epoxyazadiradione		NF-κB
	Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibiti...		NF-κB
TP1615	IKKγ NBD Inhibitory Peptide
	A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal al...
T60703	HOIPIN-1
	HOIPIN-1 (JTP-0819958) is a selective inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC 50 = 2.8 μM) that...
T39077	Aeruginosin 865
	Aeruginosin 865, isolated from terrestrial cyanobacterium Nostoc sp . Luke ová 30/93, is the first aeruginosin-type pept...
TN3219	7,8-Didehydrocimigenol		NF-κB , TNF , ERK , IκB/IKK , Akt , PPAR
	7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates...		NF-κB , TNF , ERK , IκB/IKK , Akt , PPAR
T11240	Ethacrynic acid D5		Others
	Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airw...		Others
T37449	SR 12460
	SR 12460 is a mimetic of the IκB kinase β (IKKβ) NEMO/IKKγ-binding domain (NBD) that inhibits the protein-protein intera...
T68729	Coumaperine
	Coumaperine is an NF-kB inhibitor.
T28065	ML263	ML-263 , ML 263
	ML263 inhibits NF-kB activation induced by B-cell specific antigen receptor.
T29013	HE 3286	Triolex , HE-3286 , HE3286
	Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.
T62359	TLR4/NF-κB/MAPK-IN-1
	TLR4/NF-κB/MAPK-IN-1 is a novel anti-neuroinflammatory agent with inhibitory effects on the TLR4/NF-kB/MAPK pathway.
T4361	CBL0137 hydrochloride	CBLC137 , CBL0137 , Curaxin-137 hydrochloride , CBL-C137 hydrochloride , Curaxin 137	Others , NF-κB , p53
	CBL0137 activates p53 and inhibits NF-kB (EC50: 0.37/0.47 μM) in the cell-based p53 and NF-kB reporter assays, respectiv...		Others , NF-κB , p53
T21480	Diethylmaleate	DIETHYL MALEATE , Maleic acid, diethyl ester	NF-κB
	Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.		NF-κB
T8981	WAY-169916	WAY169916 , WAY 169916	NF-κB
	WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER). It acts by inhibiting NF-kB transcriptional activ...		NF-κB
T8951	JTP 0819958 - HOIPIN-1		IκB/IKK
	JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM[1]. JTP-0819...		IκB/IKK
T63107	Anti-inflammatory agent 6
	Anti-inflammatory agent 6 exhibits anti-inflammatory potential by blocking the phosphorylation of Iκb kinase α/β (IKKα/β...
T0335	Sodium salicylate	Salicylic acid sodium salt , 2-Hydroxybenzoic acid sodium salt	Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
	Sodium salicylate, a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.		Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
TN1874	Liriodendrin		Potassium Channel , ATPase , Prostaglandin Receptor
	Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial ...		Potassium Channel , ATPase , Prostaglandin Receptor