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Search Results for " nf-kb信号通路 "

Targets

3

Compounds

3

Natural Products

1

Libraries

Cat No. Product Name Synonyms Targets
T5209 INH14 IκB/IKK
INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).
T11886 LTβR-IN-1 Others , NF-κB , LTR
LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor. LTβR-IN-1 has a selective inhibitory effect on the nuclear translocation of p52 of TNF12A, and has no obvious effect on the nuclear translocation o...
T71827 AG-205
(rac)-AG-205 serves as a robust inhibitor of the progesterone receptor membrane component 1 (Pgrmc1), crucial for inducing genes linked to sterol synthesis, notably the INSIG1 protein, which interacts with PGRMC1. Additi...
Cat No. Product Name Synonyms Targets
T4S1540 Myrislignan Apoptosis , NF-κB
Myrislignan has anti-inflammatory, and anti-cancer activities, it inhibited NF-κB signalling pathway activation, inhibited the proliferation of A549 cells in a dose- and time-dependent manner, it also significantly induc...
T5S0761 Nitidine chloride Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T3826 Polygalasaponin F NF-κB , TLR , Akt , PI3K
Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...
Cat No. Product Name
L3800 NF-κB Signaling Compound Library

740 compounds
A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
TargetMol