par1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T38836L	Protease-Activated Receptor-1, PAR-1 Agonist acetate		Protease-activated Receptor
	Protease-Activated Receptor-1, PAR-1 Agonist acetate is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist acetate corresponds to PAR1 tethered ligand and whi...		Protease-activated Receptor
T12870	SCH79797 dihydrochloride		Apoptosis , Others , Protease-activated Receptor
	SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects.		Apoptosis , Others , Protease-activated Receptor
T1893	Parmodulin 2	ML 161	Protease-activated Receptor
	Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb...		Protease-activated Receptor
T38836	Protease-Activated Receptor-1, PAR-1 Agonist
	Protease-Activated Receptor-1 (PAR-1) Agonist, a selective peptide, activates the PAR-1 receptor by mimicking the specific actions of thrombin. It corresponds to the PAR1 tethered ligand, facilitating selective activatio...
T7625	TRAP-6	PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)	Protease-activated Receptor
	TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).		Protease-activated Receptor
T36288	Protease-Activated Receptor-1, PAR-1 Agonist TFA
	Protease-Activated Receptor-1 (PAR-1) Agonist TFA is a selective peptide that acts as an agonist for the proteinase-activated receptor-1 (PAR-1). Corresponding to the tethered ligand of PAR-1, this compound mimics the ac...
T7573L	TFLLR-NH2 2TFA(197794-83-5(free base))		Protease-activated Receptor
	TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).		Protease-activated Receptor
T7013	Vorapaxar	SCH 530348,MK-5348	Protease-activated Receptor
	Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).		Protease-activated Receptor
T3098	Vorapaxar sulfate	SCH 530348 sulfate,Zontivity,vorapaxar monosulfate	Protease-activated Receptor
	Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.		Protease-activated Receptor
T7573	TFLLR-NH2	TFLLR-NH2(2TFA)	Protease-activated Receptor
	TFLLR-NH2(2TFA) is an agonist of PAR1 (EC50 :1.9 μM).		Protease-activated Receptor
T23282	RWJ-56110		Others
	protease-activated receptor-1 (PAR1) antagonist		Others
T28734	SCH79797	SCH 79797,SCH-79797
	SCH-79797 is a potent and selective PAR1 antagonist.
T23208	Q94 hydrochloride		Others
	PAR1 negative allosteric modulator		Others
T28477	PZ-128	PZ 128
	PZ-128, a PAR1 antagonist, is used potentially for the treatment of thrombosis.
TP1334	TFLLR-NH2(TFA)
	TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM. EC50: 1.9 μM (PAR1)
T78545	FLLRN	TRAP-6 (2-6)
	FLLRN is a biologically active peptide serving as a PAR1-specific antagonist.
T71109	BAY-386
	BAY-386 is a PAR1 receptor inhibitor which suppresses activation of thrombin and platelet activity.
T35867	TRAP-6 Peptide (trifluoroacetate salt)
	TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1). It acts as an agonist of PAR1, inducing platelet aggregation in human platelet-rich plasma ex vivo (EC50 = 0.8 μM)....
T23237	RLLFT-NH2		Others
	TFLLR-NH2, reversed amino acid sequence control peptide, is a PAR1 selective agonist that significantly increases the nociceptive threshold.		Others
T26744	BAY-598 R-isomer	BAY598 R-isomer,BAY 598 R-isomer
	BAY-598 R-isomer is the R-isomer of BAY589, which is used as a reference compound. It is is an inhibitor of lysine N-methyltransferase (SMYD2) and is selective for SMYD2 over protease-activated receptor 1 (PAR1).
TP1965	Parstatin(human)	Parstatin (human)
	Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 3 μM), and induces cell cycle arrest. Promotes activation...
TP1966	Parstatin(mouse)	Parstatin (mouse)
	Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 20 μM), and induces cell cycle arrest. Promotes activatio...
T80111	TRAP-5 amide
	TRAP-5 amide is a peptide agonist for protease-activated receptor 1 (PAR 1) [1].
T36717	RWJ-56110 dihydrochloride
	RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits...