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Search Result

Search Results for "parp"

Targets

PARP

Libraries

Clinical Compound Library Anti-Breast Cancer Compound Library
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Compounds

Cat No. Product Name
T10896L CSRM617 hydrochloride CSRM617 hydrochloride(787504-88-5 Free base) Others , Apoptosis , Androgen Receptor
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regula...
T22094 JGB1741 ILS-JGB-1741 Sirtuin
JGB1741 is a potent and selective inhibitor of SIRT1 with an IC50 of 15 μM. JGB1741 modulates Bax/Bcl2 ratio, cytochrome...
T16761 RK-287107 PARP , Others
RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, ...
T8184 Fucosterol PARP , Endogenous Metabolite , PPAR
Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates ...
T9891 PARP1-IN-8  N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide PARP
PARP1-IN-8 is an effective inhibito of PARP1 (IC50 = 97 nM).
T60019 VPC-70063 Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)- PARP , Apoptosis , c-Myc
VPC-70063 is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with an I...
T40310 PARP/EZH2-IN-1
PARP/EZH2-IN-1 is a first-in-class dual PARP ( IC 50 6.87 nM) and EZH2 ( IC 50 36.51 nM) inhibitor for triple-negative b...
T61798 PARP-1-IN-1
PARP-1-IN-1 is a high selective and orally active PARP-1 inhibitor ( IC 50 =0.96 nM). PARP-1-IN-1 has well tolerance and...
T61962 PARP-1/HDAC-IN-1
PARP-1/HDAC-IN-1 is an effective dual inhibitor of PARP-1/HDAC6, with IC50 of 68.90 nM and 510 nM respectively. PARP-1/H...
T39139 PARP1-IN-6
PARP1-IN-6 is a dual tubulin/PARP-1 inhibitor with IC 50 values of 0.94 and 0.48 μM, respectively.
T35763 PARP1-IN-5 dihydrochloride
PARP1-IN-5 dihydrochloride is a low toxicity, orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). PARP...
T24597 PARPi-FL Olaparib-bodipy FL , Olaparib bodipy FL
PARPi-FL is an agent of fluorescent PARP imaging. In vitro, it is capable of detecting the target engagement of a PARP i...
T60039 KSQ-4279
USP1-IN-1 (Formula I) is a USP1 and PARP inhibitor (extracted from patent WO2021163530).
T36251 DP-C-4
DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1]. DP-C-4 (1-50 μM; 24 hours) has ...
T61335 Rucaparib hydrochloride
Rucaparib (AG014699) hydrochloride is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) wi...
T61657 Rucaparib acetate
Rucaparib (AG014699) acetate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K...
T36304 Fluorescein-NAD+
Fluoroscein NAD+ is a substrate for ADP-ribosylation, providing a convenient non-isotopic alternative to radiolabelled N...
T41176 PARPYnD
PARPYnD is a potent photoaffinity probe for poly(ADP-ribose) polymerase (PARP) (IC50 values for PARP2, PARP1 and PARP6 a...
T62044 Anticancer agent 71
Anticancer agent 71 (Compound 4b) is a potent anticancer agent. Anticancer agent 71 arrests cell cycle at G2/M phase. An...
CSRM617 hydrochloride
T10896L
synonym: CSRM617 hydrochloride(787504-88-5 Free base)
Target:
JGB1741
T22094
synonym: ILS-JGB-1741
Target:
RK-287107
T16761
synonym:
Target:
Fucosterol
T8184
synonym:
Target:
PARP1-IN-8 
T9891
synonym: N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide
Target:
VPC-70063
T60019
synonym: Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-
Target:
PARP/EZH2-IN-1
T40310
synonym:
Target:
PARP-1-IN-1
T61798
synonym:
Target:
PARP-1/HDAC-IN-1
T61962
synonym:
Target:
PARP1-IN-6
T39139
synonym:
Target:
PARP1-IN-5 dihydrochloride
T35763
synonym:
Target:
PARPi-FL
T24597
synonym: Olaparib-bodipy FL , Olaparib bodipy FL
Target:
KSQ-4279
T60039
synonym:
Target:
DP-C-4
T36251
synonym:
Target:
Rucaparib hydrochloride
T61335
synonym:
Target:
Rucaparib acetate
T61657
synonym:
Target:
Fluorescein-NAD+
T36304
synonym:
Target:
PARPYnD
T41176
synonym:
Target:
Anticancer agent 71
T62044
synonym:
Target:
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