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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20571 | Cis-PDA | cis PDA | GluR , NMDAR , iGluR |
cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses. | |||
T31792 | Filaminast | UNII-CDD69JC61J,Way-pda-641,WAY-PDA 641,CDD69JC61J | PDE |
Filaminast (UNII-CDD69JC61J) is an analog of a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and roliplam, which is used as an anti-asthma drug. | |||
T33808 | 12-Oxo phytodienoic acid | 12-Oxo-Phytodienoic acid,12-OPDA,12-oxo PDA,OPDA | Others |
12-Oxo phytodienoic acid (12-oxo PDA) is an endogenous signal converter that increases alkaloid biosynthesis in E. californica cell cultures, increases b. dioica tendril curls, And inhibited jasmonic acid-induced program... | |||
T4367 | Mycro 3 | Mycro-3 | c-Myc , Autophagy |
Mycro 3 is potent and selective for c-Myc in whole cell assays. | |||
T18997 | GPDA | Glycylproline p-nitroanilide tosylate,GPN | Others |
GPDA (Glycylproline p-nitroanilide tosylate) is a substrate of X-Prolyl dipeptidyl-aminopeptidase in the enzyme assay. | |||
T77661 | H-NTPDase-IN-4 | Phosphatase | |
h-NTPDase-IN-4 is a pan-inhibitor of NTPDase, which can inhibit h-NTPDase1, 1h-NTPDase2, h-NTPDase3, h-NTPDase8. The IC50 values were 3.58 μM, 10.21 μM, 0.13 μM and 13.57 μM, respectively. | |||
T79622 | H-NTPDase-IN-3 | Phosphatase | |
h-NTPDase-IN-3 is an h-NTPDase inhibitor that inhibits h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NTPDase8. | |||
T10877 | CPDA | Phosphatase | |
CPDA is a new potent inhibitor of SH2 domain-containing inositol phosphatase 2 (SHIP2). | |||
T79492 | H-NTPDase8-IN-1 | Phosphatase | |
h-NTPDase8-IN-1 is a specific aminosulfonylbenzamide inhibitor of h-NTPDases8 (IC 50 = 0.28 ± 0.07 μM). h-NTPDase8-IN-1 can be used to study diseases brought about by aberrant h -NTPDase expression. | |||
T79607 | H-NTPDase-IN-2 | hNTPDase-IN-2 | Phosphatase |
h-NTPDase-IN-2 is a broad-spectrum NTPDase inhibitor that inhibits multiple h-NTPDas isoforms. | |||
T79491 | H-NTPDase-IN-1 | Phosphatase | |
h-NTPDase-IN-1 (Compound 3i) is an inhibitor of human NTPDase (h-NTPDase) with IC50 values of 2.88 μM for h-NTPDase1 and 0.72 μM for h-NTPDase3, indicating its potential utility for thrombosis, inflammation, diabetes, an... | |||
T61377 | NTPDase-IN-1 | ||
NTPDase-IN-1 (compound 5a) is a selective inhibitor of NTPDase enzymes. It shows inhibitory activity against h-NTPDase-1, h-NTPDase-2, and h-NTPDase-8 with IC50 values of 0.05 μM, 0.23 μM, and 0.54 μM, respectively. NTPD... | |||
TQ0114 | CMPDA | GluR | |
CMPDA is a positive allosteric modulator of AMPA receptors (EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor). | |||
T73552 | BPDA2 | ||
BPDA2 is a highly selective and competitive SHP2 inhibitor, exhibiting IC50 values of 92.0 nM for SHP2, and 33.39 μM and 40.71 μM for SHP1 and SHP1B, respectively. This compound effectively downregulates mitogenic and ce... | |||
T62703 | NTPDase-IN-2 | ||
NTPDase-IN-2 (compound 5g) selectively inhibits NTPDase-2 and NTPDase-8 with IC50 values of 0.04 µM and 2.27 µM, respectively, and exhibits non-competitive inhibition towards h-NTPDase-1 and h-NTPDase-2, with a Km of 74 ... | |||
T24604 | PDAT | Propyl Dimethyl Amino Tryptamine | |
PDAT is a noncompetitive Indolethylamine N-methyltransferase inhibitor. | |||
T23179 | PPDA | Others | |
Subtype-selective NMDA receptor antagonist | |||
T79623 | H-NTPDase-IN-5 | Phosphatase | |
h-NTPDase-IN-5 (compound 3b) serves as a pan-inhibitor of NTPDase, exhibiting inhibitory concentration 50 (IC50) values of 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), and 0.32 μM (h-NTPDase8). | |||
T62633 | NTPDase-IN-3 | ||
NTPDase-IN-3 (Compound 5e), an inhibitor of NTPDase, exhibits IC50 values of 0.38 μM (NTPDase3), 0.05 μM (NTPDase8), 0.21 μM (NTPDase1), and 1.07 μM (NTPDase2). It is utilized in cancer and thrombosis research [1]. | |||
T37396 | 13-epi-12-oxo Phytodienoic Acid | ||
13-epi-12-oxo Phytodienoic acid (13-epi-12-oxo PDA) is a lipoxygenase metabolite of α-linolenic acid in the leaves of green plants such as corn. ω-3 and ω-6 polyunsaturated fatty acids in plants are substrates for plant ... | |||
T68713 | RX-RA 69 | ||
RX-RA 69 is a pyrimido-pyrimidine derivative and PDA-inhibitor which inhibits tumor cell induced platelet aggregation in vitro. | |||
TQ0095 | Brincidofovir | CMX001,HDP-CDV | Others , Antiviral , HSV |
Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses. |