Search Result

Search Results for " pi3k/akt/mtor�� "

Libraries

PI3K-AKT-mTOR Compound Library Anti-Prostate Cancer Compound Library Anti-Liver Cancer Compound Library

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Compounds

Cat No.	Product Name
T60564	PI3K/Akt/mTOR-IN-2		PI3K , mTOR , Akt , Apoptosis
	PI3K/Akt/mTOR-IN-2 is a potent PI3K/AKT/mTOR inhibitor.PI3K/Akt/mTOR-IN-2 has anticancer effects and is selective for MD...		PI3K , mTOR , Akt , Apoptosis
T63455	PI3K/Akt/mTOR-IN-3
	PI3K/Akt/mTOR-IN-3 is a potent inhibitor of PI3K/Akt/mTOR. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 cells (IC5...
TN1891	Lupiwighteone		Apoptosis , BCL , PARP , Caspase
	Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.		Apoptosis , BCL , PARP , Caspase
TN4761	Phellamurin		P-gp
	Phellamurin inhibits intestinal P-glycoprotein in a dose-dependent manner, there is a serious interaction occurred betwe...		P-gp
TN1405	Arnicolide D		Caspase , PI3K , STAT , Akt , mTOR
	Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cy...		Caspase , PI3K , STAT , Akt , mTOR
T0365	Thioridazine hydrochloride	Mellaril,Aldazine	Adrenergic Receptor , 5-HT Receptor , Dopamine Receptor , Autophagy , Apoptosis , Potassium Channel , Antibacterial
	Thioridazine, an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonis...
T5740	25(R,S)-Ruscogenin	(25RS)-Ruscogenin	Others , HIF
	(25RS)-Ruscogenin is a natual product.		Others , HIF
T1967	AZD-3463	ALK/IGF1R inhibitor	IGF-1R , Apoptosis , Autophagy , ALK
	AZD3463, an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.		IGF-1R , Apoptosis , Autophagy , ALK
T2P2806	Hederacolchiside A1	Raddeanoside R13	mTOR , PI3K , ERK , Apoptosis , Parasite , MEK , Akt
	Hederacolchiside A1 shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of de...		mTOR , PI3K , ERK , Apoptosis , Parasite , MEK , Akt
T1826	PI3K-IN-1	XL765,SAR245409,Voxtalisib (SAR245409, XL765) Analogue,Voxtalisib Analogue	PI3K , DNA-PK
	Voxtalisib (SAR245409, XL765)Analogue is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR...		PI3K , DNA-PK
T2S2382	3'-Hydroxypterostilbene	3'-HPT	Apoptosis , Autophagy
	3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells w...		Apoptosis , Autophagy
T4672	Brevilin A		JAK , Autophagy , Anti-infection , Apoptosis , STAT
	Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 si...		JAK , Autophagy , Anti-infection , Apoptosis , STAT
T2078	Fimepinostat	CUDC-907,CUDC 907,PI3K/HDAC Inhibitor	PI3K , Apoptosis , HDAC
	CUDC-907 is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylas...		PI3K , Apoptosis , HDAC
T6334	Ridaforolimus	MK-8669,Deforolimus,AP23573	Autophagy , mTOR
	Ridaforolimus is a small molecule and non-prodrug analogue of the lipophilic macrolide antibiotic rapamycin with potenti...		Autophagy , mTOR
T5497	AMAROGENTIN		Apoptosis , AMPK
	Amarogentin is mainly extracted from Swertia and Gentiana roots. It plays cemopreventive/therapeutic role during liver c...		Apoptosis , AMPK
T4325	COTI-2	COTI 2,COTI2	Apoptosis , p53
	COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the p53 protein with potential antineo...		Apoptosis , p53
T2S0410	Euphorbia factor L1	Euphorbiasteroid	P-gp , Apoptosis
	1. Euphorbia factor L1 can enhance the ATP hydrolysis activity of ABCB1 stimulated by verapamil. 2. Euphorbia factor L1 ...		P-gp , Apoptosis
T64219	PI3K/mTOR Inhibitor-6
	PI3K/mTOR Inhibitor-6 (Compound 19c) is a potent dual PI3K/mTOR inhibitor that is more stable than gedatolisib in artifi...
T29165	XC-302 free base	XC-302,Puquitinib,XC 302,XC302
	XC-302 is a multi-targeted inhibitor, it induces autophagy of nasopharyngeal cancer cells via inhibiting the PI3K/AKT/mT...
T64041	PI3K/mTOR Inhibitor-7
	PI3K/mTOR Inhibitor-7 is a potent dual PI3K/mTOR inhibitor. PI3K/mTOR Inhibitor-7 is 4.7-fold more potent than gedatolis...