Search Result

Search Results for " pkb "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T8427	Borussertib		Akt
	Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt(IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt)		Akt
T14034	3CAI		Akt
	3CAI is a potent and specific AKT1 and AKT2 inhibitor which showed significant inhibition of AKT in an in vitro kinase assay and suppressed expression of AKT direct downstream targets such as mTOR and GSK3β as well as in...		Akt
T8969	API-1	NSC177223	Akt
	API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .		Akt
T7315	BAY1125976		Akt
	BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)		Akt
T14072	A-443654		ERK , VEGFR , GSK-3 , FLT , Casein Kinase , MAPK , Akt , PKA , Chk , CDK , Src , PKC , S6 Kinase
	A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).
T6139	A-674563	A674563	ERK , GSK-3 , Akt , PKA , CDK
	A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.		ERK , GSK-3 , Akt , PKA , CDK
T3132	SC66		Apoptosis , Akt
	SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 μg/ml, at 72 h).		Apoptosis , Akt
T3346	AKT inhibitor VIII	AKTi-1/2	Apoptosis , Akt
	AKT inhibitor VIII (AKTi-1/2) is a highly specific Akt1/2 inhibitor (IC50: 58/210 nM). The selectivity for Akt1 is higher about 36-fold than Akt3.		Apoptosis , Akt
T1920	Capivasertib	AZD5363	Akt , PKA , mTOR , Autophagy
	Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity. Capivasertib has antitumor activity for the treatment of breast cancer.		Akt , PKA , mTOR , Autophagy
T2042	CTX-0294885		Others
	CTX-0294885, a novel bisanilino pyrimidine, exhibits inhibitory activity against a broad range of kinases in vitro and is further developed into a Sepharose-supported kinase capture reagent.		Others
T13862	Recilisib	Ex-RAD,ON 01210	Akt , PI3K
	Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.		Akt , PI3K
T0033	Miltefosine	HePC,Hexadecyl phosphocholine	Akt , HIV Protease , PKC
	Miltefosine (HePC) is the treatment of visceral and cutaneous leishmaniasis drug , and is proceeding clinical trials for this in several countries. Several medical agents produce some potency against visceral or cutaneou...		Akt , HIV Protease , PKC
T6285	GSK-690693	GSK690693	Serine Protease , Akt , PKC , AMPK , Autophagy
	GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.		Serine Protease , Akt , PKC , AMPK , Autophagy
T13376	YS-49		RAAS , Akt , PI3K , Adrenergic Receptor
	YS-49 is an activator of PI3K/Akt (a downstream target of RhoA).		RAAS , Akt , PI3K , Adrenergic Receptor
T7879	TASP0415914		Akt , PI3K
	TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T		Akt , PI3K
T14327	AS1949490		Phosphatase
	AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM.		Phosphatase
T6997	SU6656		FAK , Akt , Src
	SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.		FAK , Akt , Src
T6304	AT7867		Akt , PKA , S6 Kinase
	AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.		Akt , PKA , S6 Kinase
T6849	Uprosertib	GSK2141795,GSK795	Akt
	Uprosertib (GSK2141795) (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.		Akt
T2420	PHT-427	PHT 427,CS-0223	Apoptosis , Akt , PDK
	PHT-427 (CS-0223) is a dual Akt (Ki: 2.7 μM) and PDPK1 (Ki: 5.2 μM) inhibitor (high-affinity binding for the PH domains of Akt and PDPK1).		Apoptosis , Akt , PDK
T7506	Yoda 1		Piezo Channel
	Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively)		Piezo Channel
T7885	Afuresertib hydrochloride		ROCK , Akt , PKC
	Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)		ROCK , Akt , PKC
T6303	CCT128930		Akt , PKA , S6 Kinase , Autophagy
	CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.		Akt , PKA , S6 Kinase , Autophagy
T4496	LM22B-10	LM22B10	ERK , Trk receptor , Akt
	LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor and can induce TrkB, TrkC, ERK and AKT activation in vitro and in vivo.		ERK , Trk receptor , Akt
T2667	PIK-75		Apoptosis , DNA-PK , PI3K
	PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).		Apoptosis , DNA-PK , PI3K
T9393	(E)-Akt inhibitor-IV	(E)-AKTIV,CS-1992	Akt
	(E)-Akt inhibitor-IV ((E)-AKTIV) ((E)-AKTIV) is an inhibitor of PI3K-Akt.		Akt
T6252	Ipatasertib	GDC-0068,RG7440	Akt
	Ipatasertib (GDC-0068) (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively.		Akt
T2482	AT13148		ROCK , SGK , Akt , PKA , S6 Kinase
	AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.		ROCK , SGK , Akt , PKA , S6 Kinase
T1911	Afuresertib	GSK2110183C,GSK2110183	ROCK , Akt , PKC
	Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity.		ROCK , Akt , PKC
T2274	SC79	SC 79	Akt
	SC79 is an AKT agonist with specificity and blood-brain barrier permeability. SC79 specifically binds to the PH domain of AKT, activates cytoplasmic AKT, and inhibits AKT membrane translocation. SC79 has neuroprotective ...		Akt
T3198L	PRE-084 hydrochloride		Sigma receptor
	PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).		Sigma receptor
T0708	Oxaprozin	Oxaprozinum,Wy21743	NF-κB , COX
	Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classification of oxaprozin is Nonsteroidal Anti-inflammatory Compound...		NF-κB , COX
T3467	Miransertib	ARQ-092,AKT inhibitor 2	Akt , Parasite
	Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor.		Akt , Parasite
T9831	MKC-1	Ro-31-7453	Apoptosis , Akt , Microtubule Associated , mTOR
	MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the format...		Apoptosis , Akt , Microtubule Associated , mTOR
T2171	SEW2871	SEW2871	S1P Receptor , LPL Receptor
	SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, an...		S1P Receptor , LPL Receptor
T4489	AKT-IN-1	AZD26,AZD-26,AZD 26	Akt
	AKT-IN-1 (AZD-26) is an allosteric AKT inhibitor (IC50: 1.04 μM).		Akt
T0223	Tetrahydroxyquinone	4-benzoquinone,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone	Apoptosis , Antioxidant , Reactive Oxygen Species
	Tetrahydroxyquinone (Tetroquinone) is a molecule best known as a primitive anticataract drug, is also a highly redox active molecule that can take part in a redox cycle with semiquinone radicals, leading to the formation...		Apoptosis , Antioxidant , Reactive Oxygen Species
T2492	Perifosine	NSC 639966,D21266,KRX-0401	Apoptosis , Akt , Autophagy
	Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.		Apoptosis , Akt , Autophagy
T1952	MK-2206 dihydrochloride	MK-2206 2HCl	Apoptosis , Akt , Autophagy
	MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor a...		Apoptosis , Akt , Autophagy
T6303L	CCT128930 hydrochloride	CCT128930 hydrochloride(885499-61-6 Free base)	Apoptosis , Akt , PKA , mTOR , Autophagy
	CCT128930 hydrochloride (CCT128930 hydrochloride) is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28...		Apoptosis , Akt , PKA , mTOR , Autophagy
T15374	Ipatasertib dihydrochloride	GDC-0068 dihydrochloride,RG-7440 dihydrochloride	Akt , PKA
	Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively).		Akt , PKA
TP1197	Sincalide	SQ19844,CCK-8,Cholecystokinin octapeptide	Others
	Sincalide (CCK-8) is a cholecystokinetic drug administered by injection to aid in diagnosing disorders of the gallbladder and pancreas. It is the 8-amino acid C-terminal fragment of cholecystokinin.		Others
T6065	Triciribine	VD-0002,Tricyclic nucleoside,NSC 154020,API-2,TCN	Akt , HIV Protease , DNA/RNA Synthesis
	Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.		Akt , HIV Protease , DNA/RNA Synthesis
T8656	CAY10404	3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T	Apoptosis , Akt , COX
	CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cel...		Apoptosis , Akt , COX
T5508	PF-AKT400	AKT protein kinase inhibitor	Akt
	PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt.		Akt
T1637	Deferoxamine Mesylate	desferrioxamine B,Desferrioxamine B mesylate,DFO,DFOM	Mitophagy , Beta Amyloid , Others , Ferroptosis , HIF/HIF Prolyl-Hydroxylase , Autophagy
	Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor. Deferoxamine Mesylate binds free iron into a stable complex and reduces iron accumulation. Deferoxamine Mesylate up-regulates HIF-1α levels and i...
T21312	Afatinib	Afatinib free base,BIBW 2992	EGFR , Autophagy
	Afatinib (BIBW 2992) is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively).		EGFR , Autophagy
T2287	PIK-75 hydrochloride	PIK-75 HCl,PIK-75	Apoptosis , DNA-PK , PI3K
	PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.		Apoptosis , DNA-PK , PI3K
T1773	Afatinib Dimaleate	BIBW2992,Afatinib,BIBW 2992MA2,Afatinib (BIBW2992) Dimaleate	EGFR , HER , Autophagy
	Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic act...		EGFR , HER , Autophagy
T35528	TD52		Apoptosis , Phosphatase , Akt
	TD52 is an orally active inhibitor of cancerous inhibitor of PP2A (CIP2A). TD52 is an Erlotinib derivative and indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter.		Apoptosis , Phosphatase , Akt

Compounds

Target: ERK, VEGFR, GSK-3, FLT, Casein Kinase, MAPK, Akt, PKA, Chk, CDK, Src, PKC, S6 Kinase

A-674563

T6139

Synonym: A674563

Target: ERK, GSK-3, Akt, PKA, CDK

SC66

T3132

Synonym:

Target: Apoptosis, Akt

AKT inhibitor VIII

T3346

Synonym: AKTi-1/2

Target: Apoptosis, Akt

Capivasertib

T1920

Synonym: AZD5363

Target: Akt, PKA, mTOR, Autophagy

Synonym: Ex-RAD,ON 01210

Target: Akt, PI3K

Miltefosine

T0033

Synonym: HePC,Hexadecyl phosphocholine

Target: Akt, HIV Protease, PKC

GSK-690693

T6285

Synonym: GSK690693

Target: Serine Protease, Akt, PKC, AMPK, Autophagy

YS-49

T13376

Synonym:

Target: RAAS, Akt, PI3K, Adrenergic Receptor

Target: FAK, Akt, Src

AT7867

T6304

Synonym:

Target: Akt, PKA, S6 Kinase

Uprosertib

T6849

Synonym: GSK2141795,GSK795

Target: Akt

PHT-427

T2420

Synonym: PHT 427,CS-0223

Target: Apoptosis, Akt, PDK

Yoda 1

T7506

Synonym:

Target: Piezo Channel

Afuresertib hydrochloride

T7885

Synonym:

Target: ROCK, Akt, PKC

CCT128930

T6303

Synonym:

Target: Akt, PKA, S6 Kinase, Autophagy

LM22B-10

T4496

Synonym: LM22B10

Target: ERK, Trk receptor, Akt

PIK-75

T2667

Synonym:

Target: Apoptosis, DNA-PK, PI3K

(E)-Akt inhibitor-IV

T9393

Synonym: (E)-AKTIV,CS-1992

Target: Akt

Ipatasertib

T6252

Synonym: GDC-0068,RG7440

Target: ROCK, SGK, Akt, PKA, S6 Kinase

Afuresertib

T1911

Synonym: GSK2110183C,GSK2110183

Target: ROCK, Akt, PKC

PRE-084 hydrochloride

T3198L

Synonym:

Target: Sigma receptor

Oxaprozin

T0708

Synonym: Oxaprozinum,Wy21743

Target: NF-κB, COX

Miransertib

T3467

Synonym: ARQ-092,AKT inhibitor 2

Target: Akt, Parasite

MKC-1

T9831

Synonym: Ro-31-7453

Target: Apoptosis, Akt, Microtubule Associated, mTOR

SEW2871

T2171

Synonym: SEW2871

Target: S1P Receptor, LPL Receptor

AKT-IN-1

T4489

Synonym: AZD26,AZD-26,AZD 26

Target: Akt

Tetrahydroxyquinone

T0223

Synonym: 4-benzoquinone,Tetrahydroxybenzoquinone,Tetrahydroxy-1,Tetrahydroxy-1,4-benzoquinone,Tetroquinone

Target: Apoptosis, Antioxidant, Reactive Oxygen Species

Perifosine

T2492

Synonym: NSC 639966,D21266,KRX-0401

Target: Apoptosis, Akt, Autophagy

MK-2206 dihydrochloride

T1952

Synonym: MK-2206 2HCl

Target: Apoptosis, Akt, Autophagy

CCT128930 hydrochloride

T6303L

Synonym: CCT128930 hydrochloride(885499-61-6 Free base)

Target: Apoptosis, Akt, PKA, mTOR, Autophagy

Ipatasertib dihydrochloride

T15374

Synonym: GDC-0068 dihydrochloride,RG-7440 dihydrochloride

Target: Akt, PKA

Sincalide

TP1197

Synonym: SQ19844,CCK-8,Cholecystokinin octapeptide

Target: Others

Triciribine

T6065

Synonym: VD-0002,Tricyclic nucleoside,NSC 154020,API-2,TCN

Target: Akt, HIV Protease, DNA/RNA Synthesis

CAY10404

T8656

Synonym: 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T

Target: Apoptosis, Akt, COX

PF-AKT400

T5508

Synonym: AKT protein kinase inhibitor

Target: Akt

Deferoxamine Mesylate

T1637

Synonym: desferrioxamine B,Desferrioxamine B mesylate,DFO,DFOM

Target: Mitophagy, Beta Amyloid, Others, Ferroptosis, HIF/HIF Prolyl-Hydroxylase, Autophagy

Afatinib

T21312

Synonym: Afatinib free base,BIBW 2992

Target: EGFR, Autophagy

PIK-75 hydrochloride

T2287

Synonym: PIK-75 HCl,PIK-75

Target: Apoptosis, DNA-PK, PI3K

Afatinib Dimaleate

T1773

Synonym: BIBW2992,Afatinib,BIBW 2992MA2,Afatinib (BIBW2992) Dimaleate

Target: EGFR, HER, Autophagy

TD52

T35528

Synonym:

Target: Apoptosis, Phosphatase, Akt

Cat No.	Product Name	Synonyms	Targets
T2S2215	Crebanine		Apoptosis , Others , Akt
	1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rat...		Apoptosis , Others , Akt
T7190	Actein		Apoptosis , Akt , JNK , Autophagy
	Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in...		Apoptosis , Akt , JNK , Autophagy
T6677	Sophocarpine		ERK , p38 MAPK , NF-κB , TLR , COX , HER , JNK , STAT
	Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.		ERK , p38 MAPK , NF-κB , TLR , COX , HER , JNK , STAT
T17280	(Z)-Guggulsterone		Apoptosis , VEGFR , Akt
	(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.		Apoptosis , VEGFR , Akt
T5S0896	Loureirin A		Akt , PI3K
	Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related pept...		Akt , PI3K
TN1433	Batatasin III		FAK , Others , Akt
	Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT signals and possesses anti-cancer activities. Batatasin III has a long-term inhibitory effect on whole-...		FAK , Others , Akt
T6S0781	Phellodendrine	Phallodendrin	Others , NF-κB , Akt
	1. Phellodendrine (Phallodendrin) has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.		Others , NF-κB , Akt
T3844	Deltonin		ERK , Others , Akt , Endogenous Metabolite
	Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).		ERK , Others , Akt , Endogenous Metabolite
T13803	N-Oleoyl glycine		Cannabinoid Receptor , Akt , Endogenous Metabolite , PPAR
	N-Oleoyl Glycine, a Lipoamino Acid, Stimulates Adipogenesis Associated With Activation of CB1 Receptor and Akt Signaling Pathway in 3T3-L1 Adipocyte		Cannabinoid Receptor , Akt , Endogenous Metabolite , PPAR
T3861	Isobavachalcone	Corylifolinin,Isobacachalcone	Apoptosis , Others , Reactive Oxygen Species , Akt , Autophagy
	Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in brain diseases associated with inflammation.
T6817	Deguelin	(-)-Deguelin,(-)-cis-Deguelin	Apoptosis , Akt , PI3K , Autophagy
	Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.		Apoptosis , Akt , PI3K , Autophagy
T5654	Musk ketone		Others
	Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.		Others
T5S0506	Rotundic acid	Rutundic acid	Apoptosis , Others , p38 MAPK , Akt , mTOR
	Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) c...		Apoptosis , Others , p38 MAPK , Akt , mTOR
T3895	Polyphyllin I		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
	Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
T2746	Sophocarpine monohydrate	Sophocarpine	Apoptosis , Influenza Virus , Akt , PI3K , AMPK , Autophagy
	Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.		Apoptosis , Influenza Virus , Akt , PI3K , AMPK , Autophagy
TN1968	N-Feruloyloctopamine	N-Feruloyloctopamine	p38 MAPK , Akt
	N-Feruloyloctopamine is a natural product.		p38 MAPK , Akt
T6S0619	Pachymic acid	3-O-Acetyltumulosic acid	ERK , Akt
	Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.		ERK , Akt
T2798	Esculetin	Aesculetin,Cichorigenin	Lipoxygenase , Akt , PI3K
	Esculetin (Cichorigenin) is a coumarin derivative from various natural plant products with various biological and pharmaceutical properties including anti-edema, anti-inflammatory and anti-tumour effects. It inhibits lip...		Lipoxygenase , Akt , PI3K
T7912	(−)-Myrtenal	(1R)-(−)-Myrtenal	Others
	(−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.		Others
T5574	Guggulsterone	Guggulsterone E&Z	Apoptosis , FXR , Akt , Caspase , JNK , Autophagy
	Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.		Apoptosis , FXR , Akt , Caspase , JNK , Autophagy
TN1405	Arnicolide D		Akt , Caspase , PI3K , STAT , mTOR
	Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling path...		Akt , Caspase , PI3K , STAT , mTOR
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
T3001	Honokiol	NSC 293100	ERK , HCV Protease , MEK , Akt , Autophagy
	Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.		ERK , HCV Protease , MEK , Akt , Autophagy
T6427	Butein	2’,3,4,4’-tetrahydroxy Chalcone	Apoptosis , EGFR , Others , PDE , Autophagy
	Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.		Apoptosis , EGFR , Others , PDE , Autophagy
T2790	Oridonin	NSC-250682,Rubescenin,Isodonol,Rubescensin A	Akt , Antibacterial
	Oridonin (NSC-250682) is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2.		Akt , Antibacterial
T2789	Scutellarin	Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide	Akt , HIV Protease , STAT
	Scutellarin (Scutellarein-7-glucuronide), an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regulate the STAT3/Girdin/Akt signal...		Akt , HIV Protease , STAT
T5740	25(R,S)-Ruscogenin	(25RS)-Ruscogenin	Others , HIF
	25(R,S)-Ruscogenin is a natual product.		Others , HIF
T4S21320	ISOGINKGETIN	4',4'''-Dimethylamentoflavone	MMP , Others
	1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti...		MMP , Others
T2974	Cyclovirobuxine D	CVB-D,Bebuxine,Cyclovirobuxin D	Apoptosis , Others , Akt , mTOR , Autophagy
	Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.		Apoptosis , Others , Akt , mTOR , Autophagy
T0392	Artemisinin	Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,Artemisinine	HCV Protease , Ferroptosis , Akt , Parasite
	Artemisinin (Qinghaosu) is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of malarial organisms, including chloroquine-resistant Plasmodium ...		HCV Protease , Ferroptosis , Akt , Parasite
T2P2806	Hederacolchiside A1	Raddeanoside R13	Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
	Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...		Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T3P2904	α-Linolenic acid	Alpha-Linolenic Acid,Linolenic acid	Akt , PI3K
	α-Linolenic acid (Alpha-Linolenic Acid) is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostagland...		Akt , PI3K
T1205	Chloramphenicol	Chlornitromycin,Levomycetin,Chloromycetin	ribosome , HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Chloramphenicol (Chloromycetin), a broad-spectrum antibiotic, blocks bacterial protein synthesis.
TN1033	Sennidin A		HCV Protease , transporter , Akt , PI3K
	Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 μM.		HCV Protease , transporter , Akt , PI3K
T2163	Dihydrocapsaicin	CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide	Others , TRP/TRPV Channel
	Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...		Others , TRP/TRPV Channel
TN1034	Sennidin B		HCV Protease , transporter , Akt , PI3K
	Sennidin B stimulates glucose incorporation in rat adipocytes.		HCV Protease , transporter , Akt , PI3K
T2851	Daphnetin	7,8-Dihydroxycoumarin,Daphnetol	EGFR , PKA , PKC , Parasite , Autophagy
	Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...		EGFR , PKA , PKC , Parasite , Autophagy
T4085	Paris saponin VII	Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII	Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
	Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
T5736	1,3-Dicaffeoylquinic acid	CYNARIN,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid	Reactive Oxygen Species , Akt , PI3K
	1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.		Reactive Oxygen Species , Akt , PI3K
TN4179	Haginin A		ERK , Tyrosinase , Akt
	Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt/PKB activation, MITF, and also by the subsequent downregulation of t...		ERK , Tyrosinase , Akt

Natural Products

Crebanine

T2S2215

Synonym:

Target: Apoptosis, Others, Akt

Actein

T7190

Synonym:

Target: Apoptosis, Akt, JNK, Autophagy

Sophocarpine

T6677

Synonym:

Target: ERK, p38 MAPK, NF-κB, TLR, COX, HER, JNK, STAT

(Z)-Guggulsterone

T17280

Synonym:

Target: Apoptosis, VEGFR, Akt

Target: FAK, Others, Akt

Phellodendrine

T6S0781

Synonym: Phallodendrin

Target: Others, NF-κB, Akt

Deltonin

T3844

Synonym:

Target: ERK, Others, Akt, Endogenous Metabolite

N-Oleoyl glycine

T13803

Synonym:

Target: Cannabinoid Receptor, Akt, Endogenous Metabolite, PPAR

Isobavachalcone

T3861

Synonym: Corylifolinin,Isobacachalcone

Target: Apoptosis, Others, Reactive Oxygen Species, Akt, Autophagy

Deguelin

T6817

Synonym: (-)-Deguelin,(-)-cis-Deguelin

Target: Apoptosis, Akt, PI3K, Autophagy

Synonym: Rutundic acid

Target: Apoptosis, Others, p38 MAPK, Akt, mTOR

Polyphyllin I

T3895

Synonym:

Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy

Sophocarpine monohydrate

T2746

Synonym: Sophocarpine

Target: Apoptosis, Influenza Virus, Akt, PI3K, AMPK, Autophagy

N-Feruloyloctopamine

TN1968

Synonym: N-Feruloyloctopamine

Target: p38 MAPK, Akt

Pachymic acid

T6S0619

Synonym: 3-O-Acetyltumulosic acid

Target: ERK, Akt

Esculetin

T2798

Synonym: Aesculetin,Cichorigenin

Target: Lipoxygenase, Akt, PI3K

(−)-Myrtenal

T7912

Synonym: (1R)-(−)-Myrtenal

Target: Others

Guggulsterone

T5574

Synonym: Guggulsterone E&Z

Target: Apoptosis, FXR, Akt, Caspase, JNK, Autophagy

Arnicolide D

TN1405

Synonym:

Target: Akt, Caspase, PI3K, STAT, mTOR

Glaucocalyxin A

T4S0498

Synonym: Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Polygalasaponin F

T3826

Synonym:

Target: NF-κB, TLR, Akt, PI3K

Honokiol

T3001

Synonym: NSC 293100

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Butein

T6427

Synonym: 2’,3,4,4’-tetrahydroxy Chalcone

Target: Apoptosis, EGFR, Others, PDE, Autophagy

Oridonin

T2790

Synonym: NSC-250682,Rubescenin,Isodonol,Rubescensin A

Target: Akt, Antibacterial

Scutellarin

T2789

Synonym: Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide

Target: Akt, HIV Protease, STAT

25(R,S)-Ruscogenin

T5740

Synonym: (25RS)-Ruscogenin

Target: Others, HIF

ISOGINKGETIN

T4S21320

Synonym: 4',4'''-Dimethylamentoflavone

Target: MMP, Others

Cyclovirobuxine D

T2974

Synonym: CVB-D,Bebuxine,Cyclovirobuxin D

Target: Apoptosis, Others, Akt, mTOR, Autophagy

Artemisinin

T0392

Synonym: Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,Artemisinine

Target: HCV Protease, Ferroptosis, Akt, Parasite

Hederacolchiside A1

T2P2806

Synonym: Raddeanoside R13

Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

α-Linolenic acid

T3P2904

Synonym: Alpha-Linolenic Acid,Linolenic acid

Target: Akt, PI3K

Chloramphenicol

T1205

Synonym: Chlornitromycin,Levomycetin,Chloromycetin

Target: ribosome, HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic

Sennidin A

TN1033

Synonym:

Target: HCV Protease, transporter, Akt, PI3K

Dihydrocapsaicin

T2163

Synonym: CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide

Target: Others, TRP/TRPV Channel

Sennidin B

TN1034

Synonym:

Target: HCV Protease, transporter, Akt, PI3K

Daphnetin

T2851

Synonym: 7,8-Dihydroxycoumarin,Daphnetol

Target: EGFR, PKA, PKC, Parasite, Autophagy

Paris saponin VII

T4085

Synonym: Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy

1,3-Dicaffeoylquinic acid

T5736

Synonym: CYNARIN,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid

Target: Reactive Oxygen Species, Akt, PI3K

Haginin A

TN4179

Synonym:

Target: ERK, Tyrosinase, Akt

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04552	AKT1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ...
TMPY-04553	AKT3 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	v-akt murine thymoma viral oncogene homolog 3 (AKT3), also known as PKB-GAMMA, with AKT1/PKBalpha, AKT2/PKBbeta, are the memerbers of Akt kinase family, share extensive structural similarity and perform common as well as...
TMPH-01534	ITPKB Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	ITPKB Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-02676	EGFR Protein, Mouse, Recombinant (His)	Mouse	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-04818	EGFR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-00742	EGFR Protein, Human, Recombinant (His)	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-04529	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPK-00351	RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)	Human	HEK293
	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPK-00723	RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPY-03724	EGFR Protein, Canine, Recombinant (His)	Canine	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-02675	EGFR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06524	EGFR Protein, Feline, Recombinant (His)	Feline	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05612	EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05637	EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05211	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-02958	EGFR Protein, Rat, Recombinant (His)	Rat	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-00128	EGFR Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05258	EGFR Protein, Human, Recombinant (Isoform Viii, hFc)	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-01043	EGFR Protein, Human, Recombinant (hFc)	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06593	EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06549	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPJ-01094	CD161 Protein, Human, Recombinant (C-hFc)	Human	Human Cells
	Killer cell lectin-like receptor subfamily B, member 1(KLRB1) is a single-pass type II membrane protein which contains 1 C-type lectin domain. KLRB1 plays an inhibitory role on natural killer (NK) cells cytotoxicity. Act...
TMPJ-01095	CD161 Protein, Human, Recombinant (N-hFc)	Human	Human Cells
	Killer cell lectin-like receptor subfamily B, member 1(KLRB1) is a single-pass type II membrane protein which contains 1 C-type lectin domain. KLRB1 plays an inhibitory role on natural killer (NK) cells cytotoxicity. Act...
TMPJ-00674	RANK/TNFRSF11A Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member of tumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acid...
TMPY-04574	AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST)	Mouse	Baculovirus-Insect Cells
	v-akt murine thymoma viral oncogene homolog 3 (AKT3), also known as PKB-GAMMA, with AKT1/PKBalpha, AKT2/PKBbeta, are the memerbers of Akt kinase family, share extensive structural similarity and perform common as well as...
TMPY-04446	AKT3 Protein, Mouse, Recombinant (aa 106-479)	Mouse	Baculovirus-Insect Cells
	v-akt murine thymoma viral oncogene homolog 3 (AKT3), also known as PKB-GAMMA, with AKT1/PKBalpha, AKT2/PKBbeta, are the memerbers of Akt kinase family, share extensive structural similarity and perform common as well as...
TMPY-04484	ACK1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	ACK1 (also known as ACK, TNK2, or activated Cdc42 kinase) is a structurally unique non-receptor tyrosine kinase that is expressed in diverse cell types. This downstream effector of CDC42 mediates CDC42-dependent cell mig...
TMPH-00273	IGF1/IGF-I Protein, Bovine, Recombinant (hFc)	Bovine	Yeast
	The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose ...

AKT1 Protein, Human, Recombinant (His)

TMPY-04552

Species: Human

Expression System: Baculovirus-Insect Cells

AKT3 Protein, Human, Recombinant (GST)

TMPY-04553

Species: Human

Expression System: Baculovirus-Insect Cells

ITPKB Protein, Human, Recombinant (His & SUMO)

TMPH-01534

Species: Human

Expression System: E. coli

EGFR Protein, Mouse, Recombinant (His)

TMPY-02676

Species: Mouse

Expression System: HEK293

EGFR Protein, Cynomolgus, Recombinant (His)

TMPY-04818

Species: Cynomolgus

Expression System: HEK293

EGFR Protein, Human, Recombinant (His)

TMPY-00742

Species: Human

Expression System: HEK293

EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)

TMPY-04529

Species: Human

Expression System: Baculovirus-Insect Cells

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)

TMPK-00351

Species: Human

Expression System: HEK293

RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)

TMPK-00723

Species: Mouse

Expression System: HEK293

EGFR Protein, Canine, Recombinant (His)

TMPY-03724

Species: Canine

Expression System: Baculovirus-Insect Cells

EGFR Protein, Mouse, Recombinant (hFc)

TMPY-02675

Species: Mouse

Expression System: HEK293

EGFR Protein, Feline, Recombinant (His)

TMPY-06524

Species: Feline

Expression System: Baculovirus-Insect Cells

EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated

TMPY-05612

Species: Human

Expression System: HEK293

EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated

TMPY-05637

Species: Human

Expression System: Baculovirus-Insect Cells

EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)

TMPY-05211

Species: Human

Expression System: Baculovirus-Insect Cells

EGFR Protein, Rat, Recombinant (His)

TMPY-02958

Species: Rat

Expression System: HEK293

EGFR Protein, Rhesus, Recombinant (hFc)

TMPY-00128

Species: Rhesus

Expression System: HEK293

EGFR Protein, Human, Recombinant (Isoform Viii, hFc)

TMPY-05258

Species: Human

Expression System: Baculovirus-Insect Cells

EGFR Protein, Human, Recombinant (hFc)

TMPY-01043

Species: Human

Expression System: HEK293

EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated

TMPY-06593

Species: Human

Expression System: HEK293

EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)

TMPY-06549

Species: Human

Expression System: HEK293

CD161 Protein, Human, Recombinant (C-hFc)

TMPJ-01094

Species: Human

Expression System: Human Cells

CD161 Protein, Human, Recombinant (N-hFc)

TMPJ-01095

Species: Human

Expression System: Human Cells

RANK/TNFRSF11A Protein, Mouse, Recombinant (His)

TMPJ-00674

Species: Mouse

Expression System: Human Cells

AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST)

TMPY-04574

Species: Mouse

Expression System: Baculovirus-Insect Cells

AKT3 Protein, Mouse, Recombinant (aa 106-479)

TMPY-04446

Species: Mouse

Expression System: Baculovirus-Insect Cells

ACK1 Protein, Human, Recombinant (GST)

TMPY-04484

Species: Human

Expression System: Baculovirus-Insect Cells

IGF1/IGF-I Protein, Bovine, Recombinant (hFc)

TMPH-00273

Species: Bovine

Expression System: Yeast

Cat No.	Product Name
L1300	PI3K-AKT-mTOR Compound Library		425 compounds
	A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;

Libraries

PI3K-AKT-mTOR Compound Library

L1300

Compounds: 425