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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T78835 | Phosphatase-IN-1 | Antifungal | |
Phosphatase-IN-1 is a Propranolol derivative, a phosphatidic acid phosphatase (Pah) inhibitor with antifungal activity.Phosphatase-IN-1 is effective in inhibiting the growth of plant pathogens at a concentration of 60 μM... | |||
T4671 | BN82002 | CDC25 Phosphatase Inhibitor I | Phosphatase |
BN82002 (CDC25 Phosphatase Inhibitor I) is a synthetic inhibitor of CDC25 phophatases | |||
T67036 | Acid phosphatase | ||
Acid phosphatase is a useful organic compound for research related to life sciences. The catalog number is T67036 and the CAS number is 9001-77-8. | |||
T10877 | CPDA | Phosphatase | |
CPDA is a new potent inhibitor of SH2 domain-containing inositol phosphatase 2 (SHIP2). | |||
T7150 | BTdCPU | Apoptosis , Phosphatase , PERK | |
BTdCPU is a potent activator of heme-regulated eIF2α kinase (HRI) . BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell. | |||
T81550 | PAP 248–286 | Prostatic Acid Phosphatase(248-286) | |
Prostatic Acid Phosphatase (248-286), or PAP (248-286), is a biologically active peptide and a semen-derived enhancer of viral infection (SEVI) factor present in semen. It significantly amplifies HIV infection by promoti... | |||
T10486 | BCI | (E)-BCI | Phosphatase |
BCI ((E)-BCI) is an allosteric inhibitor of dual-specificity phosphatase (DUSP; EC50s: 13.3 and 8.0 μM for DUSP6 and DUSP1 in cells) and does not inhibit DUSP5. | |||
T7820 | Raphin1 | Phosphatase | |
Raphin1 is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). | |||
T3045 | Salubrinal | Apoptosis , Phosphatase , PERK , Autophagy , HSV | |
Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α). | |||
T2417 | Sal003 | Apoptosis , Phosphatase , PERK | |
Sal003, an effective cell-permeable analog, inhibitis the eIF2α phosphatase. | |||
T2747 | Endothall | Others | |
Endothall is an effective protein phosphatase 2A (PP2A) inhibitor, exerting inhibitory effects on both PP2A and PP1, with IC50 values of 90 nM and 5 µM, respectively. It exhibits anticancer activity, making it suitable f... | |||
T4308 | F1063-0967 | Phosphatase | |
F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC50 of 11.62 μM. | |||
T16859 | SBI-425 | Others | |
SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP). SBI-425 effectively inhibits TNAP in the vasculature and improves cardiovascular parameters and survival withou... | |||
T16762 | RMC-4550 | Phosphatase | |
RMC-4550 is an effective and allosteric inhibitor of SHP2 (IC50: 0.583 nM). | |||
T7078 | NSC 95397 | Apoptosis , Phosphatase | |
NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively). | |||
T7381 | TCS 401 | Phosphatase | |
TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B; Ki = 0.29 µM) | |||
T12901 | SHIP2-IN-1 | Phosphatase | |
SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 µM),and used in the research of Alzheimer’s disease. | |||
T6521 | GSK 2830371 | GSK2830371 | Phosphatase |
GSK 2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM. | |||
T4256 | PTP1B-IN-2 | Phosphatase | |
PTP1B-IN-2 is an effective protein tyrosine phosphatase 1B (PTP1B) inhibitor(IC50=50 nM). | |||
T1927 | CCT007093 | Apoptosis , Phosphatase , Autophagy | |
CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM). | |||
T9156 | CDC25B-IN-2 | Phosphatase , mTOR | |
BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression. | |||
T8519 | Raphin1 acetate | Phosphatase | |
Raphin1 acetate is a selective and orally bioavailable regulatory phosphatase PPP1R15B (R15B) inhibitor. | |||
T6667 | SF1670 | PTP CD45 Inhibitor,PTPase CD45 Inhibitor | Phosphatase , PTEN , Autophagy |
SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM. | |||
T14841 | BVT948 | Phosphatase , P450 , Histone Methyltransferase | |
BVT948 is a protein tyrosine phosphatase (PTP) inhibitor. It can also inhibit several CYP450 isoforms and lysine methyltransferase SETD8 (KMT5A). | |||
T14177 | Alexidine dihydrochloride | Apoptosis , Others , Antifungal | |
Alexidine dihydrochloride has antifungal and antibiofilm activity against a diverse range of fungal pathogens. Alexidine dihydrochloride is an anticancer agent that targets a mitochondrial tyrosine phosphatase, PTPMT1, i... | |||
T3962 | TPI-1 | TPI 1,TPI1 | Phosphatase , Glucocorticoid Receptor |
TPI-1 is a SHP-1 inhibitor. | |||
T7323 | BCI-215 | Phosphatase | |
BCI-215 causes selective cancer cell cytotoxicity in part through non-redox-mediated activation of MAPK signaling | |||
T7411 | Rbin-1 | Ribozinoindole-1 | ATPase , Phosphatase |
Rbin-1 (Ribozinoindole-1) is a potent,specific inhibitor of eukaryotic ribosome biogenesis. | |||
T0827 | Cefsulodin sodium | Cefsulodine sodium,Sulcephalosporin | Antibacterial , Antibiotic |
Cefsulodin sodium (Sulcephalosporin) hydrate is a β lactam antibiotic. | |||
T16350 | NSC-87877 | Apoptosis , Phosphatase | |
NSC-87877 is an effective inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (IC50=0.318 μM, 0.355 μM of shp2 and shp1, respectively).It also inhibits dual-specificity phosphatase 26 (DUSP26). | |||
T3544 | SHP099 hydrochloride | Phosphatase , Others | |
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor. | |||
T41298 | LMPTP INHIBITOR 1 dihydrochloride | Phosphatase | |
LMPTP Inhibitor 1 Dihydrochloride is a compound selectively targeting low molecular weight protein tyrosine phosphatase (LMPTP), exhibiting potent inhibitory activity with an IC50 value of 0.8 μM for LMPTP-A. | |||
T4340 | SPI-112 | Phosphatase | |
SPI-112, the SPI-112 methyl ester analog, can inhibit cellular Shp2 PTP activity. SPI-112 bound to Shp2 by surface plasmon resonance (SPR) and displayed competitive inhibitor kinetics to Shp2. | |||
TQ0032 | Rosiptor | AQX-1125 | Phosphatase |
Rosiptor (AQX-1125) (AQX-1125) is an orally-active and specific phosphatase SHIP1 activator with anti-inflammatory effects. | |||
T7953 | BpV(HOpic) | bpV (HOpic) | PTEN |
BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM). | |||
T7012 | VO-Ohpic trihydrate | VO-Ohpic | PTEN , Autophagy |
VO-Ohpic trihydrate (VO-Ohpic) is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM. | |||
T22215 | 1-Naphthyl phosphate potassium salt | Phosphatase | |
1-Naphthyl phosphate potassium salt inhibits non-specific phosphatase. | |||
T16724 | Razuprotafib | AKB-9778 | Phosphatase , Others |
Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury. | |||
T13013 | Sodium stibogluconate | Stibogluconate trisodium nonahydrate | Phosphatase |
Sodium stibogluconate (Stibogluconate trisodium nonahydrate) is a potent protein tyrosine phosphatase inhibitor. | |||
T39658 | RMC-4630 | SHP2-IN-7,RMC-4630 | Phosphatase |
RMC-4630 is an inhibitor of SHP2. | |||
T23133 | Pentamidine | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal | |
Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication. | |||
T9744 | MP07-66 | Phosphatase | |
MP07-66 is a novel FTY720-analog devoid of immunosuppressive effects leads to the reactivation of PP2A, which in turn triggers apoptosis of CLL cells. | |||
T8985 | NSC45586 | Others | |
NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2. | |||
T7704 | KY-226 | Phosphatase | |
KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,) | |||
T13176 | TNO155 | Batoprotafib | Phosphatase |
TNO155 is a protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11) inhibitor(IC50 : 0.011 µM),with potential antineoplastic activity. | |||
T3564 | SHP099 | SHP099 free base,SHP 099,SHP-099 | Phosphatase , PERK |
SHP099 (SHP099 free base) free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhib... | |||
T6911 | NSC-87877 disodium | NSC87877 | Apoptosis , Phosphatase |
NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduce... | |||
T14327 | AS1949490 | Phosphatase | |
AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM. | |||
T9196 | IACS-13909 | BBP-398 | Phosphatase |
IACS-13909 (BBP-398), a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway. | |||
T9205 | NCGC00378430 | Phosphatase , Others | |
NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor that disrupts the SIX1/EYA2 complex, EMT, and Metastasis. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35951 | Alkaline Phosphatase | Others | |
Alkaline Phosphatase is an ubiquitous membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at basic pH values. | |||
TN1859 | Licoflavone A | Phosphatase | |
Licoflavone A is a natural product isolated from the roots of Glycyrrhiza uralensis. | |||
TN1305 | Ethoxysanguinarine | 6-Ethoxydihydrosanguinarine | Apoptosis , AChR |
Ethoxysanguinarine (6-Ethoxydihydrosanguinarine) shows human blood acetylcholinesterase (HuAChE) and human plasma butyrylcholinesterase (HuBuChE) inhibitory activity, with IC50 values of 0.83 +/- 0.04 microM and 4.20 +/-... | |||
T6S2116 | Ginkgolic acid C17:1 | Phosphatase , PTEN | |
1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes. | |||
T3880 | Silydianin | Silidianin | Phosphatase |
Silydianin (Silidianin) exerts inhibition of UGT in human liver. Silydianin exerts inhibition of OATP1B1, OATP1B3 (unknown origin) expressed in HEK293 cells. Silydianin exerts inhibition of OATP2B1 (unknown origin) expre... | |||
TN1124 | Neoeriocitrin | AChE | |
Neoeriocitrin is a natural product isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor. | |||
T4915 | β-Glycerophosphate disodium salt hydrate | Phosphatase , Endogenous Metabolite | |
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It func... | |||
T3780 | Oroxin B | Hypocretin-2 | Apoptosis , PTEN , Antioxidant , PI3K , Autophagy |
Oroxin B (Hypocretin-2) has antioxidant activity. | |||
TN1362 | Afzelin | Kaempferol-3-O-rhamnoside | PTEN , p38 MAPK , TNF , Mitochondrial Metabolism , Antibacterial , Prostaglandin Receptor , Autophagy |
Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protect human skin from UVB-induced d... | |||
T0945 | Cyclosporin A | Cyclosporine A,Ciclosporin,Cyclosporine | Phosphatase , Antibiotic , Complement System |
Cyclosporin A is a naturally occurring cyclic polypeptide that is the active metabolite of a fungus. Cyclosporin A is an immunosuppressant that binds to procyclins and inhibits calcineurin (IC50=7 nM). | |||
TN2111 | Prunin | Naringenin 7-0-glucoside | Phosphatase , Anti-infection , Virus Protease |
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can... | |||
T2144 | Tacrolimus | Fujimycin,FK506,FR900506 | Phosphatase , Others , Antibacterial , Antibiotic , mTOR , Autophagy |
Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein phosphatase. | |||
T5891 | D-ERYTHRO-SPHINGOSINE | trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine | Phosphatase , Endogenous Metabolite , PKC |
D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator | |||
T4852 | Trimyristin | Trimyristoylglycerol,Tritetradecanoin,Glyceryl trimyristate,1,2,3-Tritetradecanoylglycerol | Phosphatase , Endogenous Metabolite , AChE |
Trimyristin (Tritetradecanoin) is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging from yeast to humans. In humans, glyceryl trimyristate is i... | |||
TN1053 | Aloe-emodin-8-O-β-D-glucopyranoside | Aloe-emodin-8-O-beta-D-glucopyranoside | Phosphatase |
Aloe-emodin-8-O-β-D-glucopyranoside (Aloe-emodin-8-O-beta-D-glucopyranoside) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro. | |||
T20879 | Tacrolimus monohydrate | FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506 | Phosphatase , Others , Antibacterial , Antibiotic , Autophagy |
Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi... | |||
T2185 | L-Ascorbic acid 2-phosphate trisodium | L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate | Reactive Oxygen Species , c-Met/HGFR , Endogenous Metabolite |
L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays. | |||
T3827 | Rhein-8-glucoside calcium | Rhein-8-O-β-D-glucopyranoside,Rhein-8-glucoside calcium salt | Phosphatase , Antibacterial |
Rhein-8-O-beta-D-glucopyranoside(Rhein-8-glucoside calcium (Rhein-8-glucoside calcium salt) salt) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro. | |||
T3938 | H-HomoArg-OH.HCl | NSC 145416,L-Homoarginine hydrochloride,L(+)-Homoarginine hydrochloride | Endogenous Metabolite , Phosphorylase |
H-HomoArg-OH.HCl (L-Homoarginine hydrochloride) is a specific inhibitor of liver-type alkaline phosphatase. | |||
T8103 | H-HoArg-OH | Endogenous Metabolite , Phosphorylase | |
H-HoArg-OH, a homologue arginine, is a strong inhibitor of human liver and bone alkaline phosphatase. | |||
T3855 | Tracheloside | Estrogen Receptor/ERR , Phosphorylase | |
Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml). | |||
T3804 | Neomangiferin | Mangiferin 7-glucoside | Phosphatase |
Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical mar... | |||
TN1470 | Cassiaside B2 | Phosphatase , MAO , 5-HT Receptor | |
Cassiaside B2 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A).Cassiaside B2 is an agonist of the 5-HT2C receptor with anti-allergic activity.Cassiaside B2 is one of the a... | |||
T65128 | Tartaric acid disodium dihydrate | Disodium L-(+)-Tartrate Dihydrate | Phosphatase , Endogenous Metabolite |
Tartaric acid disodium dihydrate (Disodium L-(+)-Tartrate Dihydrate) is commonly used as a buffer in molecular biology and cell culture.Tartaric acid disodium dihydrate is an acid phosphatase inhibitor that increases the... | |||
T10109 | 3-Carene | Delta-3-Carene | COX , Antifungal |
3-Carene(Delta-3-Carene) is a bicyclic monoterpene extracted from western larch and Douglas-fir that acts as a phytofungicide.3-Carene inhibits inflammatory infiltrates and COX-2 overexpression induced by nociceptive sti... | |||
T2133 | Adenosine monophosphate | 5'-Adenylic acid,AMP,Adenosine 5'-monophosphate | Endogenous Metabolite , AMPK |
Adenosine monophosphate (AMP) is a purine ribonucleoside 5'-monophosphates and a key cellular metabolite in signal transduction and regulation of energy homeostasis.It has a role as an EC 3.1.3.11 (fructose-bisphosphatas... | |||
T2481 | Ascomycin | FK520,Immunomycin,FR-900520 | Phosphatase , Others , Antibiotic , Parasite , Antifungal |
Ascomycin (Immunomycin)(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties. | |||
T2P2923 | Stearic acid | Isostearic acid,Octadecanoic acid,Cetylacetic acid | Phosphatase , Endogenous Metabolite |
1. Stearic acid (Cetylacetic acid) can reduce metastatic tumor burden. 2. Stearic acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes. 3. Stearic acid and its derivatives have... | |||
TN6926 | Paeonoside | Others | |
Paeonoside is a bioactive compound found in P. suffruticosa that promotes wound healing and migration during osteoblast differentiation.Paeonoside has some antidiabetic activity and prevents sepsis and sepsis-induced dea... | |||
T4839 | Ac-Ala-OH | N-Acetylalanine,N-Acetyl-L-alanine | Others , Endogenous Metabolite |
Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro... | |||
T3S1612 | Kuwanon G | Moracenin B,Kuwanone G | Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase |
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a... | |||
T0256 | Citric acid trilithium salt tetrahydrate | Lithium citrate tribasic tetrahydrate,Trilithium citrate tetrahydrate | Dehydrogenase , GSK-3 , HIF/HIF Prolyl-Hydroxylase , Antibacterial , GluR |
Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways... | |||
T23421 | Tautomycetin | Others | |
protein phosphatase (PP)1 inhibitor | |||
TN5400 | Aerugidiol | ||
Aerugidiol inhibits protein tyrosine phosphatase 1B (PTP1B). | |||
T19885 | Methyllucidone | ||
Methyllucidone is an inhibitor of STAT3 that acts by regulating the expression of the protein tyrosine phosphatase MEG2. | |||
T70725 | Motuporin | ||
Motuporin is an inhibitor of type-1 and type-2A protein phosphatase catalytic subunits (PP-1c and PP-2Ac). | |||
T11203 | Enocyanin | Others | |
Enocyanin, an anthocyanin extracted from grapes, exhibits inhibitory effects on leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase, and esterase activity. | |||
T39219 | Ficusonolide | ||
Ficusonolide exhibits significant antidiabetic activity through its interactions with dipeptidyl peptidase-IV (DPP-IV), protein tyrosine phosphatase 1B (PTP-1B), α-glucosidase, and α-amylase. | |||
TN3335 | Abyssinone V | Phosphatase | |
Abyssinone V is a natural compound isolated from the stem bark of Erythrina melanacantha and an inhibitor of protein tyrosine phosphatase-1B (PTP1B). | |||
T70221 | Dibefurin | ||
Dibefurin is a metabolite that inhibits the activity of calcineurin, a calcium/calmodulin-dependent protein phosphatase involved in the activation of T lymphocytes. | |||
TN5207 | Ursolic aldehyde | Others | |
Ursolic aldehyde can inhibit phosphatase of regenerating liver-3, with the IC(50) value of 50 +/- 0.3 mu M. | |||
T73073 | PTP1B-IN-21 | ||
PTP1B-IN-21 is a compound that functions as a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B; IC50=1.56 μM), demonstrating a marked preference over the structurally similar T-cell protein tyrosine phosphat... | |||
T13740 | Isotanshinone IIA | Others | |
Isotanshinone IIA, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. is an abietane-type diterpene metabolite. | |||
T73072 | PTP1B-IN-20 | ||
PTP1B-IN-20 is a selective PTP1B (protein tyrosine phosphatase 1B) inhibitor, exhibiting an IC50 of 1.05 μM, and demonstrates selectivity over TCPTP (T-cell protein tyrosine phosphatase), which has an IC50 of 78.0 μM. Th... | |||
T14368 | Azadirachtin B | Others | |
Azadirachtin B, a limonoid derived from the seed kernels of Azadirachta indica, exhibits a broad spectrum of biochemical activities, including insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral, and oste... | |||
TN2887 | 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid | Phosphatase | |
(24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM. | |||
T37055 | Cytostatin | ||
Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix. Cytostatin selectively inhibits protein Phosphatase 2A. | |||
TN3215 | 7,4'-Dihydroxy-8-methylflavan | Others | |
7,4'-Dihydroxy-8-methylflavan can significantly promote mesenchymal stem cells (MSCs) osteogenic differentiation by increasing the levels of alkaline phosphatase (ALP) activity. 7,4'-Dihydroxy-8-methylflavan also has fre... | |||
TN2913 | 3-Acetoxy-11-ursen-28,13-olide | Phosphatase | |
3β-Acetoxy-urs-11-en-28,13-olide exhibits significant protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, it is a mixed-type PTP1B inhibitor. It exhibits weak-moderate antiproliferative activity against the A278... | |||
TN3505 | Beta-Peltoboykinolic acid | Phosphatase | |
Beta-Peltoboykinolic acid has in vitro protein tyrosine phosphatase 1B (PTP1B) inhibitory, it inhibits PTP1B with IC50 values of 5.2+/-0.5 microM. It also has cytotoxic activity. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02650 | Alkaline phosphatase Protein, Human, Recombinant (His) | Human | HEK293 |
ALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activit... | |||
TMPK-00639 | Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) | Rat | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPY-00570 | Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) | Human | Yeast |
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyro... | |||
TMPY-00663 | Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) | Human | HEK293 |
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal... | |||
TMPY-02713 | Alkaline phosphatase Protein, Human, Recombinant (hFc) | Human | HEK293 |
ALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activit... | |||
TMPY-02131 | Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST) | Human | E. coli |
The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of im... | |||
TMPK-00855 | Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPJ-00784 | Alkaline Phosphatase Protein, Human, Recombinant (aa 23-506, His) | Human | Human Cells |
ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a rol... | |||
TMPY-02155 | Prostatic Acid Phosphatase Protein, Human, Recombinant (His) | Human | HEK293 |
Prostatic acid phosphatase (PAP, or ACPP), also known as prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. As a non-specific phosphomonoesterase, Prostatic acid phosphatase is synthesized... | |||
TMPK-00802 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00804 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00803 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-01326 | Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPY-00594 | Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal... | |||
TMPY-00446 | Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal... | |||
TMPY-02672 | Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Prostatic acid phosphatase (PAP, or ACPP), also known as prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. As a non-specific phosphomonoesterase, Prostatic acid phosphatase is synthesized... | |||
TMPK-00801 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPY-04125 | PTP1B Protein, Human, Recombinant (His) | Human | E. coli |
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c... | |||
TMPY-03484 | TCPTP Protein, Human, Recombinant | Human | Baculovirus-Insect Cells |
Tyrosine-protein phosphatase non-receptor type 2, also known as T-cell protein-tyrosine phosphatase, PTPN2 and PTPT, is a cytoplasm protein that belongs to the protein-tyrosine phosphatase family and Non-receptor class 1... | |||
TMPY-05308 | CD45 Protein, Human, Recombinant (aa 1-529, His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05748 | CD45 Protein, Human, Recombinant (aa 26-577, His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02576 | PHOSPHO1 Protein, Human, Recombinant (His) | Human | E. coli |
TMPH-03236 | Alkaline phosphatase/ALPL Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). It can also u... | |||
TMPY-02766 | PSPH Protein, Human, Recombinant | Human | E. coli |
Phosphoserine phosphatase (PSPH) belongs to a subfamily of the phosphotransferases. PSPH is the rate-limiting enzyme in l-serine biosynthesis. It has previously been found that Phosphoserine phosphatase (PSPH) plays a ro... | |||
TMPJ-00996 | VHR Protein, Human, Recombinant (His) | Human | E. coli |
Human DUSP3 belongs to the dual specificity protein phosphatase subfamily. DUSPs are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues... | |||
TMPJ-01390 | MINPP1 Protein, Human, Recombinant (His) | Human | Human Cells |
Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synth... | |||
TMPJ-00908 | LMW-PTP Protein, Human, Recombinant (His) | Human | E. coli |
Low Molecular Weight Phosphotyrosine Protein Phosphatase (LMW-PTP) is a member of the low molecular weight phosphotyrosine protein phosphatase family. LMW-PTP serves as an acid phosphatase and a protein tyrosine phosphat... | |||
TMPJ-01057 | PSP Protein, Human, Recombinant (His) | Human | E. coli |
Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphose... | |||
TMPY-02127 | DUSP3 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Vaccinia H1-related phosphatase (VHR) is classified as a dual-specificity phosphatase (DUSP), and the other name is dual-specificity phosphatase 3 (DUSP3). DUSPs are a heterogeneous group of protein phosphatases that can... | |||
TMPY-03482 | DUSP3 Protein, Human, Recombinant | Human | Baculovirus-Insect Cells |
Vaccinia H1-related phosphatase (VHR) is classified as a dual-specificity phosphatase (DUSP), and the other name is dual-specificity phosphatase 3 (DUSP3). DUSPs are a heterogeneous group of protein phosphatases that can... | |||
TMPH-03161 | Alkaline Phosphatase Protein, Prevotella intermedia, Recombinant (GST & His & Myc) | Prevotella intermedia | E. coli |
Major acute phase reactant. Apolipoprotein of the HDL complex. | |||
TMPK-00684 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPJ-00465 | PTP1C Protein, Human, Recombinant (His) | Human | E. coli |
Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mi... | |||
TMPK-00796 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPY-00960 | ACP5 Protein, Human, Recombinant (His) | Human | HEK293 |
Tartrate-resistant acid phosphatase (TRACP) or acid phosphatase 5, tartrate resistant (ACP5 or TRAP) is a glycosylated monomeric metalloenzyme expressed in mammals. TRACP is associated with osteoblast migration to bone r... | |||
TMPJ-00528 | PPP1R1A Protein, Human, Recombinant (His) | Human | E. coli |
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein pla... | |||
TMPY-02595 | DUSP14 Protein, Human, Recombinant (His & MBP) | Human | E. coli |
Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosph... | |||
TMPJ-00984 | INPP1 Protein, Human, Recombinant (His) | Human | Human Cells |
Inositol Polyphosphate 1-Phosphatase (INPP1) is a member of the inositol monophosphatase family. INPP1 is widely expressed in tissues, with highest expression levels observed in the pancreas and kidney. INPP1 is inhibite... | |||
TMPJ-00944 | PPP1CC Protein, Human, Recombinant (His) | Human | E. coli |
Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractil... | |||
TMPY-01414 | ACP5 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tartrate-resistant acid phosphatase (TRACP) or acid phosphatase 5, tartrate resistant (ACP5 or TRAP) is a glycosylated monomeric metalloenzyme expressed in mammals. TRACP is associated with osteoblast migration to bone r... | |||
TMPJ-00053 | PRL-2 Protein, Human, Recombinant (His) | Human | E. coli |
PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational ... | |||
TMPJ-01205 | MDP1 Protein, Human, Recombinant (His) | Human | Human Cells |
MDP1, which is short for nesium-dependent phosphatase 1, is a 176 aa. protein. It has 3 forms by different alternative splicing. This protein belongs to the HAD-like hydrolase superfamily, and usually takes its function ... | |||
TMPJ-01117 | INPP5A Protein, Human, Recombinant (His) | Human | Human Cells |
Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme ... | |||
TMPY-02964 | Calcineurin B/PPP3R1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
PPP3R1 belongs to the calcineurin regulatory subunit family. It is a regulatory subunit of calcineurin. Calcineurin is composed of two subunits: calcineurin A (CnA) and calcineurin B (CnB). Dephosphorylation of the nucle... | |||
TMPJ-00794 | CD45 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a var... | |||
TMPY-02197 | PPM1G Protein, Human, Recombinant (aa 317-546, His) | Human | E. coli |
Protein phosphatase 1G, also known as Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, Protein phosphatase magnesium-dependent 1 gamma, PP2C-gamma, PPM1G and PPM1C, is a cytoplasm protein that belongs to the... | |||
TMPK-01079 | PLD4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. fu... | |||
TMPY-00487 | PTPN9 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Protein tyrosine phosphatase non-receptor type 9 (PTPN9), also named PTP-MEG2, is an important member of the protein tyrosine phosphatase family that is involved in variety of human diseases.PTPN9 plays an important role... | |||
TMPY-02002 | PHPT1 Protein, Human, Recombinant (His) | Human | E. coli |
PHPT1, also known as 14 kDa phosphohistidine phosphatase, phosphohistidine phosphatase 1, protein janus-A homolog, PHP14, is a cytoplasm protein which belongs to the janus family. PHPT1 / PHP14 is expressed abundantly in... | |||
TMPY-02369 | TCPTP Protein, Mouse, Recombinant (aa 2-314, His) | Mouse | Baculovirus-Insect Cells |
Tyrosine-protein phosphatase non-receptor type 2, also known as T-cell protein-tyrosine phosphatase, PTPN2 and PTPT, is a cytoplasm protein that belongs to the protein-tyrosine phosphatase family and Non-receptor class 1... | |||
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Cat No. | Product Name | ||
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L9100 | Phosphatase Inhibitor Library | 80 compounds | |
A collection of 80 phosphatase inhibitors with known activity; |