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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12721 | Rho-Kinase-IN-1 | ROCK | |
Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation dise... | |||
T2633 | GSK429286A | RHO-15 | ROCK |
GSK429286A (RHO-15) is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM). | |||
T80175 | Conopeptide rho-TIA | Adrenergic Receptor | |
Conopeptide rho-TIA, a peptide from Conus tulipa venom, acts as a selective, noncompetitive inhibitor at the human α1B-Adrenergic Receptor and as a competitive inhibitor at the α1A and α1D-Adrenergic Receptors. Binding t... | |||
T61497 | Rho-Kinase-IN-2 | ||
Rho-Kinase-IN-2 (Compound 23) is an orally active and selective inhibitor of Rho Kinase (ROCK), which can penetrate the central nervous system (CNS). It exhibits a high affinity for ROCK2 with an inhibition constant (IC5... | |||
T2155 | Thiazovivin | ROCK | |
Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC. | |||
T14960 | Chroman 1 | ROCK | |
Chroman 1 is an inhibitor of ROCK2 (IC50: 1 nM). | |||
TQ0187 | SR-3677 | ROCK , Autophagy | |
SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM). | |||
T12747 | ROCK2-IN-2 | ROCK | |
ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM). | |||
T1870 | Y-27632 | ROCK , Apoptosis | |
Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells. | |||
T7391 | SAR407899 | ROCK , Rho | |
SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries. | |||
T15798 | LX7101 | ROCK , LIM Kinase , PKA | |
LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM). | |||
T12746 | ROCK inhibitor-2 | ROCK | |
ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively). | |||
T7301 | BDP5290 | ROCK | |
BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.) | |||
T3513 | GSK180736A | GSK180736 | ROCK , GRK , PKA |
GSK180736A is an effective and selective GRK2 inhibitor (IC50: 0.77 μM) and >100-fold selectivity over other GRKs. It is a weak inhibitor of PKA (IC50: 30 μM), but highly effective against ROCK1 (IC50: 100 nM). | |||
T1898 | RKI-1447 | RKI1447 | ROCK |
RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities. | |||
T7764 | CCG-222740 | ROCK , Rho , Ras | |
CCG-222740 is an inhibitor of Rho/MRTF pathway | |||
T4095 | ZINC00881524 | ROCK inhibitor | ROCK |
ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor. | |||
T2011 | RKI1313 | RKI 1313,RKI-1313 | ROCK |
RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasion. | |||
T14989 | CMPD101 | ROCK , GRK , PKC | |
CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with I... | |||
T7885 | Afuresertib hydrochloride | ROCK , Akt , PKC | |
Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively) | |||
T4488 | GSK-25 | GSK25 | ROCK , S6 Kinase , mTOR |
GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested). | |||
T13384L | Y-33075 dihydrochloride | CaMK , ROCK , PKC | |
Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM). | |||
T7648 | HA-100 | Myosin , PKA , PKC | |
HA-100 is an inhibitor of protein kinase | |||
T4276L | Hydroxyfasudil | Hydroxy-Fasudil,HA-1100 | ROCK , PKA |
Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively). | |||
T2482 | AT13148 | ROCK , SGK , Akt , PKA , S6 Kinase | |
AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II. | |||
T1911 | Afuresertib | GSK2110183C,GSK2110183 | ROCK , Akt , PKC |
Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. | |||
T4276 | Hydroxyfasudil Hydrochloride | Hydroxyfasudil (HA-1100) HCl,HA 1100 hydrochloride | ROCK |
Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM). | |||
TQ0319 | Ripasudil | K-115,Ripasudil hydrochloride dihydrate | ROCK |
Ripasudil (Ripasudil hydrochloride dihydrate) (K-115) hydrochloride dihydrate is a specific ROCK inhibitor (IC50s: 51/19 nM for ROCK1/ROCK2). | |||
TQ0110 | ROCK-IN-2 | TC-S 7001,Azaindole 1 | ROCK |
ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2. | |||
T3518 | GSK269962A | GSK269962B,GSK 269962,GSK269962A HCl | ROCK , S6 Kinase |
GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively. | |||
T6867 | Belumosudil | KD025,Rezurock,ROCK inhibitor,SLx-2119 | ROCK |
Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM). | |||
T23308 | SAR407899 hydrochloride | ROCK | |
ATP-competitive ROCK inhibitor | |||
T14004 | 1A-116 | Rho | |
1A-116 is a specific inhibitor of Rac1 . | |||
T8473 | MLS000532223 | Rho , Ras | |
MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM). | |||
T1606 | Fasudil | HA-1077,AT877 | ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy |
Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK. | |||
T1725 | Y-27632 dihydrochloride | Y-27632 2HCl | ROCK , Apoptosis |
Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells. | |||
T4306 | CCG-203971 | CCG203971 | Rho , Ras |
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also inhibits PC-3 cell migration (IC50: 4.2 μM),... | |||
T7552 | H-1152 | ROCK | |
H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM). | |||
T3060 | Fasudil hydrochloride | Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877 | ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy |
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively. | |||
T36502 | DCP-Rho1 | DCP-Rho1 | |
DCP-Rho1 is a fluorescent probe for the detection of sulfenic acid-containing proteins.1,2 It displays excitation/emission maxima of 560/581 nm, respectively, and has been used to visualize protein oxidation sites in sit... | |||
T7492 | Ripasudil free base | K-115 (free base) | ROCK , Antibacterial |
Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent. | |||
T26078 | Rhodblock 6 | Rhodblock6,Rhodblock-6 | ROCK |
Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits the localization of phosphorylated MRLC (Myosin Regulatory Light Chain) and acts by specifically inhibiting Rho kinase activity. | |||
T16745 | Rhosin hydrochloride | Apoptosis , Rho , Ras | |
Rhosin hydrochloride is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin hydrochloride does not interact with Cdc42 o... | |||
T18977 | Dihydrorhodamine 123 | DHR 123 | Others |
Dihydrorhodamine 123 (DHR 123) is a fluorescent probe (λex=488 nm, λem=525 nm). | |||
T16743 | Rhodamine 123 | R-22420,RH-123 | Others |
Rhodamine 123 is a fluorescent dye (λex=503 nm, λem=527 nm). | |||
T19063 | Sulforhodamine B sodium salt | Acid Red 52,Kiton Red 620 | Others |
Sulforhodamine B sodium salt (Acid Red 52) is a fluorescent dye. It can be used from laser-induced fluorescence to the quantification of cellular proteins of cultured cells. | |||
T19054 | Rhodamine 800 | Others | |
Rhodamine 800 is a near-infrared fluorescent dye. | |||
T16742 | Rhodamine 110 | Rhodamine 110 chloride,RH110 | Others |
Rhodamine 110 (RH110) is a xanthene dye similar to fluorescein and eosin. | |||
T19981 | Rhoduline Acid | Di-J acid,I Acid Imide,NSC 1698 | |
Rhoduline Acid (Di-J acid) is an intermediate in the synthesis of diazo dyes and tetranitazole dyes. | |||
T16744 | Rhodamine 6G | Basic Red 1 | Others |
Rhodamine 6G (Basic Red 1) is a rhodamine analog useful in Pgp efflux assays. It can be widely used in characterizing the kinetics of MRP1- mediated efflux as a laser dye and potential mitochondrial probe. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TQ0183 | Narciclasine | Lycoricidinol | ROCK |
Narciclasine (Lycoricidinol), a natural product, modulates the Rho/Rho-kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity. | |||
T19924 | Rhododendrol | Betuligenol,Frambinol | Others |
Rhododendrol (Frambinol) is a melanin synthesis and acts by preventing high-fat diet-induced elevation in body weight and increasing lipolysis in white adipocytes in male mice. Rhododendrol can be used as the lightening/... | |||
T5S0526 | Rhodojaponin II | Others | |
1. Rhodojaponin II correlates pretty well with cardiotoxicity. | |||
T2755 | Rhoifolin | Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside | Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy |
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves. | |||
T4S0528 | Rhodojaponin V | Others , Antibacterial | |
Antibacterial; anti-inflammatory | |||
T5S0527 | Rhodojaponin III | Others | |
1. Rhodojaponin III has antifeedant and oviposition deterrence effects against many kinds of insects, BdorCSP2 of B. dorsalis could be involved in chemoreception of Rhodojaponin III and played a critical role. 2. Rhodoja... | |||
T7975 | Rhodamine B | Rhodamine B,Tetraethylrhodamine,Brilliant Pink B,Basic Violet 1,Rhodamine O | Others |
Rhodamine B (Brilliant Pink B) is used as a tracer dye in water to determine the rate and direction of flow and transport. | |||
TN2156 | Rhombifoline | Antioxidant | |
Rhombifoline is a family of alkaloids isolated from the leaf stems of Anagyrus foetida and Genista tenera. | |||
T3852 | Rhodiosin | Antioxidant , AChE | |
Rhodiosin is a compound with antioxidant activity. | |||
T2S2043 | Dracorhodin perchlorate | Dracorhodin perochlorate,Dracohodin perochlorate | Apoptosis , Others |
Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts in a dose-and time-dependent manner, arresting cell cycle at G1 phase, may as a candidate for anti-breast cancer. Dracorhodin perchlorate... | |||
TN1011 | Rhodionin | P450 , AChE | |
Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administered drugs; they can significantly suppress the elevation of ... | |||
TN4909 | (+)-Rhododendrol | Others | |
(+)-Rhododendrol shows anti-inflammatory effects, it can suppress the NO production by activated macrophages in vivo. | |||
TN2823 | 24-Norhopa-4(23),22(29)-diene-3β,6β-diol | Others | |
24-Norhopa-4(23),22(29)-diene-3β,6β-diol is a natural product for research related to life sciences. The catalog number is TN2823 and the CAS number is 194613-74-6. | |||
TN1797 | Isorhoifolin | Adrenergic Receptor | |
Isorhoifolin and vicenin II are main compounds of ethyl acetate fraction (EAcF) obtained from Erythrina velutina leaves, EAcF increases the cardiac contractile force by increasing the l-type calcium current and activatin... | |||
T40741 | Dracorhodin | ||
Dracorhodin, the primary constituent found in the sanguis draconis extract, is a flavylium compound classified within the anthocyanin family. Notably, dracorhodin possesses the ability to elicit vasodilation. | |||
TN6173 | Rhodomyrtosone I | ||
Rhodomyrtosone I is a natural product for research related to life sciences. The catalog number is TN6173 and the CAS number is 1402725-98-7. | |||
TN2155 | Rhodiocyanoside A | Histamine Receptor | |
Rhodiocyanoside A has antiallergic activity, it exhibits inhibitory activity on the histamine release from rat peritoneal exudate cells sensitized with anti-DNP IgE and inhibits the PCA reaction in rats. | |||
TN6133 | Rhodomyrtone | Rhodomyrtone A | |
Rhodomyrtone is a natural product for research related to life sciences. The catalog number is TN6133 and the CAS number is 468757-69-9. | |||
T13868 | Rhodiolin | Others | |
Rhodiolin is a natural product(flavonoid) isolated from Rhodiola fastigita. | |||
TN1350 | 9-Methoxymyrrhone | 9-Methymyrrhone | Others |
9-Methymyrrhone is a natural product | |||
T80004 | Tetrahydrorhombifoline | ||
Tetrahydrorhombifoline, a quinolizidine alkaloid found in the aerial parts of Genista vuralii A. Duran & H. Dural (Fabaceae), exhibits antibacterial and antifungal activities as evidenced by the extract from G. vuralii [... | |||
TN1963 | Myrrhone | Others | |
Myrrhone is a natural product | |||
TN4910 | Rhoeadine | Others | |
Rhoeadine is a natural product for research related to life sciences. The catalog number is TN4910 and the CAS number is 2718-25-4. | |||
T5S1261 | Methylophiopogonanone B | Ras | |
1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation. | |||
T4969 | Guanosine 5'-triphosphate trisodium salt | GTP Trisodium salt,5'-GTP trisodium salt | Endogenous Metabolite |
Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of se... | |||
T5S0053 | Coptisine | Coptisin | Indoleamine 2,3-Dioxygenase (IDO) |
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ... | |||
T4958 | (-)-Alkannin | Alkannin,Shikonin | Apoptosis , PI3K |
(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics, a... | |||
T37690 | Phenylpyropene A | ||
Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM).... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02040 | Rho GDI 1 Protein, Human, Recombinant (GST) | Human | E. coli |
Rho GDI 1 Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPH-00741 | Rho Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase wh... | |||
TMPH-02041 | ARHGEF12 Protein, Human, Recombinant (His) | Human | E. coli |
ARHGEF12 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPY-02439 | Rac2 Protein, Human, Recombinant (His) | Human | E. coli |
Ras-related C3 botulinum toxin substrate 2 (Rac2) is a small G-protein belonging to the Ras subfamily of the GTPase family. Rac2 acts as an "on / off" switch for signal transduction cascades and motilities. When GDP is a... | |||
TMPY-01187 | Rac1 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal re... | |||
TMPY-01958 | RhoA Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Transforming protein RhoA, also known as Rho cDNA clone 12, Ras homolog gene family member A, RHOA and ARH12, is a cell membrane and cytoplasm protein that belongs to the small GTPase superfamily and Rho family. The Rho ... | |||
TMPH-00299 | Rhodopsin Protein, Bovine, Recombinant (His) | Bovine | in vitro E. coli expression system |
Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change t... | |||
TMPH-00322 | Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His) | Calloselasma rhodostoma | Yeast |
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ... | |||
TMPH-03409 | 4CL Protein, Rhodobacter capsulatus, Recombinant (His) | Rhodobacter capsulatus | E. coli |
Converts p-coumaric acid into p-coumaryl CoA. This is necessary for the activation of the photoactive yellow protein (PYP) chromophore. | |||
TMPH-02044 | RHOG Protein, Human, Recombinant (His & Myc) | Human | E. coli |
RHOG Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00321 | Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO) | Calloselasma rhodostoma | E. coli |
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ... | |||
TMPH-03123 | Rhodopsin Protein, Pig, Recombinant (GST & His) | Sus scrofa (Pig) | E. coli |
Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change t... | |||
TMPH-00320 | Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His) | Calloselasma rhodostoma | Yeast |
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ... | |||
TMPH-03124 | Rhodopsin Protein, Pig, Recombinant (GST) | Sus scrofa (Pig) | E. coli |
Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change t... | |||
TMPH-00323 | Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc) | Calloselasma rhodostoma | E. coli |
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ... | |||
TMPH-02043 | RHOD Protein, Human, Recombinant (His & Myc) | Human | E. coli |
RHOD Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00324 | SVTLE Protein, Calloselasma rhodostoma, Recombinant (His) | Calloselasma rhodostoma | Yeast |
Thrombin-like snake venom serine protease that acts as an anticoagulant. It cleaves fibrinogen (FGA) to split off the A-fibrinopeptides (A, AY and AP), but not the B-fibrinopeptide. The resulting fibrin polymers are impe... | |||
TMPH-00785 | Bacteriorhodopsin Protein, Halobacterium halobium, Recombinant (His & Myc & SUMO) | Halobacterium halobium | E. coli |
Light-driven proton pump. | |||
TMPH-00300 | Rhodopsin Protein, Bovine, Recombinant (His & KSI) | Bovine | E. coli |
Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change t... | |||
TMPH-00396 | TrhO Protein, Chlamydophila felis, Recombinant (His) | Chlamydia felis | E. coli |
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs. | |||
TMPY-04018 | LRG1 Protein, Human, Recombinant | Human | HEK293 |
LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell... | |||
TMPH-02697 | GNA12 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF12/LARG). G... | |||
TMPH-01755 | NRL Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B. Functions also as a transcriptional coactivator, stimulating transcription mediated by the transc... | |||
TMPH-02804 | NRL Protein, Mouse, Recombinant (His & Myc & SUMO) | Mouse | E. coli |
Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B. Functions also as a transcriptional coactivator, stimulating transcription mediated by the transc... | |||
TMPY-03986 | PIST Protein, Human, Recombinant (His) | Human | E. coli |
GOPC, also known as PIST, interacts specifically with TC1 (a Rho-family small GTPase)] as a binding partner for Rhotekin. Rhotekin associates with PIST in vitro and both polarized and non-polarized MDCK (Madin-Darby cani... | |||
TMPH-01724 | MRTFA Protein, Human, Recombinant (His & KSI) | Human | E. coli |
Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF... | |||
TMPH-03149 | Porcine circovirus 2 (PCV2) Capsid Protein (E. coli, His) | PCV2 | E. coli |
Self-assembles to form the virion icosahedral capsid with a T=1 symmetry. This very small capsid (17 - 22 nm in diameter) allows the virus to be very stable in the environment and resistant to some disinfectants, includi... | |||
TMPH-02103 | SRF Protein, Human, Recombinant (His) | Human | Yeast |
SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with ... | |||
TMPH-01071 | CD44 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellu... | |||
TMPH-01072 | CD44 Protein, Human, Recombinant (Avi & mFc), Biotinylated | Human | HEK293 |
Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellu... | |||
TMPY-03500 | ARL2BP Protein, Human, Recombinant (His) | Human | E. coli |
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. ARL2BP binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activ... | |||
TMPY-03965 | LRG1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell... | |||
TMPH-01801 | NME2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Negativ... | |||
TMPY-03966 | LRG1 Protein, Human, Recombinant (His) | Human | HEK293 |
LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell... | |||
TMPY-02714 | PRC1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
PRC1 (protein regulator of cytokinesis 1) is a key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. It is essential for controlling the spatiotemporal formation of the... | |||
TMPH-01863 | PIEZO1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Pore-forming subunit of a mechanosensitive non-specific cation channel. Generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium. Plays a key role in ep... | |||
TMPH-01086 | CSPG4 Protein, Human, Recombinant (His & Myc) | Human | HEK293 |
Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon rege... | |||
TMPY-04397 | PAK-3 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
PAK3 is a member of PAK proteins, a family of serine/threonine p21-activating kinases, serve as effectors of small Rho GTPases Cdc42 and RAC and have been implicated in a wide range of biological activities. There are si... | |||
TMPH-01718 | MUSK Protein, Human, Recombinant (His) | Human | Yeast |
Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to ... | |||
TMPH-00561 | 30S ribosomal protein S4 Protein, E. coli, Recombinant (His) | E. coli | E. coli |
One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; With S5 and S12 plays an important role in translational accuracy; ma... | |||
TMPY-04130 | ARF1 Protein, Human, Recombinant (His) | Human | E. coli |
Invasion of tumor cells is a key step in metastasis that depends largely on the ability of these cells to degrade the extracellular matrix. The ARF1+ARF4 and ARF1+ARF3 pairs are both required for integrity of recycling e... | |||
TMPY-06746 | ARF1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | E. coli |
Invasion of tumor cells is a key step in metastasis that depends largely on the ability of these cells to degrade the extracellular matrix. The ARF1+ARF4 and ARF1+ARF3 pairs are both required for integrity of recycling e... | |||
TMPY-06637 | ARF1 Protein, Human, Recombinant (GST) | Human | E. coli |
Invasion of tumor cells is a key step in metastasis that depends largely on the ability of these cells to degrade the extracellular matrix. The ARF1+ARF4 and ARF1+ARF3 pairs are both required for integrity of recycling e... | |||
TMPH-03764 | YAP1 Protein, Human, Recombinant (His) | Human | Yeast |
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor su... |
Cat No. | Product Name | ||
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L7700 | Neural Regeneration Compound Library | 529 compounds | |
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening; |