Home Tools
Log in
Cart

Search Result

Search Results for " sting "

Targets

114

Compounds

5

Natural Products

6

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T11035 DiABZI STING agonist-1 (Tautomerism) diABZI STING agonist (Compound 3) STING
diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.
T13015 STING agonist-4 STING
STING agonist-4 is an agonist of stimulator of Interferon Genes (STING) receptor(IC50 of 20 nM).
T9853 STING activator Compound 53 STING
STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint cons...
T8328 STING agonist-1 G10 Virus Protease , STING
STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
T9028 STING-IN-2 C-170 STING
STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research.
T9029 STING-IN-3 C-171 STING
STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
T5516 DiABZI STING agonist-1 trihydrochloride STING
diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.
T60000 STING (WT/R232) activity regulator 126 STING
STING (WT/R232) activity regulator 126 is a STING modulator with antibacterial and antiviral effects.
T38161 STING Agonist C11 STING Agonist C11
STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphory...
T74809 STING agonist-30 STING
STING agonist-30 is a potent activator of the STING-dependent immune response, demonstrating significant inhibitory effects on a range of viruses such as herpes simplex virus (HSV), rotavirus, and severe acute respirator...
T5154 C-176 C176,STING inhibitor 1 STING
C-176 (STING inhibitor 1) is a strong, covalent mouse STING inhibitor
T13014L STING agonist-3 trihydrochloride STING agonist-3 trihydrochloride (2138299-29-1 free base) Others
STING agonist-3 trihydrochloride is a selective and non-nucleotide agonist of small-molecule STING(pEC50 and pEC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatme...
T38159 STING Agonist 12b
STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 ...
T38160 STING Agonist 1a
STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expres...
T13906 STING ligand-1 Others
STING ligand-1 is a lead STING ligand(IC50 of 68 nM for HAQ STING).
T13014 STING agonist-3 Others
STING agonist-3 is a selective and non-nucleotide small-molecule STING agonist(pEC50 and pIC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatment of cancer.
T75161 STING agonist-31
STING agonist-31 is a STING agonist, with EC 50 values of 0.24 and 39.51 μM for h-STING and m-STING. STING agonist-31 has antitumor efficiency [1] .
T74621 STING agonist-9
STING agonist-9 (Compound 45) is a potent STING agonist with an EC 50 of 1.2 nM and 32.82 μM against h-STING and m-STING, respectively. STING agonist-9 shows antitumor activity [1] .
T63458 STING agonist-11
STING agonist-11 is a potent activator of the small molecule cyclic urea class of STING (EC50: 18 nM).STING activation is a highly promising immunotherapy.
T72688 STING agonist-20
STING agonist-20 is a potent STING agonist used in the synthesis of XMT-2056. STING agonist-20 can be used as a vaccine adjuvant in the study of cancer and other inflammatory, immune diseases .
T81084 STING agonist-18
STING Agonist-18 (Compound 1a) is a precursor for the synthesis of antibody-drug conjugates (ADCs), including Trastuzumab conjugates [1].
T75097 STING agonist-29
STING agonist-29 (CF511) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING , exhibits activity against SARS-CoV series strains [1] .
T75095 STING agonist-27
STING agonist-27 (CF509) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING , exhibits activity against SARS-CoV series strains [1] .
T75091 STING agonist-23
STING agonist-23 (CF502) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING , increases phosphorylation of STING , TBK1 and IRF3 . STING agonist-23 promotes the levels of IFN-β , IL-6 , CX...
T75093 STING agonist-25
STING agonist-25 (CF505) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING , increases phosphorylation of STING , TBK1 and IRF3 . STING agonist-23 promotes the levels of IFN-β , IL-6 , CX...
T75096 STING agonist-28
STING agonist-28 (CF510) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING , increases phosphorylation of STING , TBK1 and IRF3 . STING agonist-23 promotes the levels of IFN-β , IL-6 , CX...
T75092 STING agonist-24
STING agonist-24 (CF504) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING , increases phosphorylation of STING , TBK1 and IRF3 . STING agonist-23 promotes the levels of IFN-β , IL-6 , CX...
T63457 STING agonist-10
STING agonist-10 is a potent activator of the STING small molecule cyclic urea class (EC50: 2600 nM).STING activation is a highly promising immunotherapy.
T72614 STING modulator-3
STING modulator-3 is a STING inhibitor. STING modulator-3 inhibits R232 STING with an K i value of 43.1 nM in scintillation proximity assay. STING modulator-3 has no effect on IRF-3 activation or TNF-β induction in THP-1...
T81082 STING-IN-7 STING
STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of 11.5 nM. It effectively hampers the phosphorylation of both...
T74267 STING agonist-17
STING agonist-17 (compound 4a) is a potent STING agonist with an IC 50 value of 0.062 nM. STING agonist-17 has anti-cancer activity for tumor immunization [1] .
T75090 STING agonist-22
STING agonist-22 (CF501) is a potent non-nucleotide STING agonist. STING agonist-22 is a adjuvant by activating STING to induce the type I interferon (IFN-I) response and proinflammatory cytokine production. STING agonis...
T83775 STING Agonist 12L Stimulator of Interferon Genes Agonist 12L
STING agonist 12L is a stimulator of interferon genes (STING) agonist that exhibits binding affinity for both wild-type STING and its variants R232, AQ, and Q with half-maximal inhibitory concentrations (IC50s) of 1.15 µ...
T74896 PROTAC STING Degrader-1
PROTAC STING Degrader-1 (Compound SP23) is a STING PROTAC degrader with a DC 50 of 3.2 μM. PROTAC STING Degrader-1 shwos anti-inflammatory activity [1] .
T61043 STING agonist-7
STING agonist-7 is an agonist of non-nucleotide STING that binds selectively to mouse STING but not human STING [1].
T75094 STING agonist-26
STING agonist-26 (CF508) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING , increases phosphorylation of STING , TBK1 and IRF3 . STING agonist-23 promotes the levels of IFN-β , IL-6 , CX...
T74719 STING-IN-6
STING-IN-6 (compound 50) is a potent STING inhibitor with a pIC 50 of 8.9. STING-IN-6 has the potential for immunity research [1] .
T74268 STING agonist-13
STING agonist-13 is a stimulator of interferon genes ( STING ) agonist, for cancer immunity via STING-mediated immune activation. STING agonist-13 can stimulate STING downstream signaling and promoting type I interferon ...
T72615 STING modulator-4
STING modulator-4 is a competitive STING modulator with a K i of 0.0933 μM for R232H STING . STING modulator-4 has an EC 50 of >10 μM for p-IRF3 in THP-1 cell .
T74718 STING modulator-5
STING modulator-5 (compound 38) is a STING modulator with a pIC 50 value of 9.5. STING modulator-5 antagonizes peripheral blood mononuclear cells (PBMC) with a pIC 50 value of 8.1. STING modulator-5 is a antagonist of TH...
T75011 STING-IN-5 STING
STING-IN-5, a potent inhibitor of the Stimulator of Interferon Genes (STING) pathway, significantly suppresses lipopolysaccharide (LPS)-induced nitric oxide (NO) synthesis in macrophages, exhibiting an IC50 of 1.15 μM. T...
T81083 STING agonist-19
STING agonist-19 serves as a precursor for the synthesis of immune-stimulating antibody conjugates (ISACs).
T83841 STING Agonist D61 D61,Stimulator of Interferon Genes Agonist D61
STING agonist D61 is a compound that activates the stimulator of interferon genes (STING), leading to the induction of IFN3-inducible secreted alkaline phosphatase (SEAP) and IFN-β-inducible reporter genes in cellular as...
T74328 STING agonist-8 dihydrochloride
STING agonist-8 dihydrochloride (compound 5-AB) is a potent STING agonist with an EC 50 of 27 nM in THP1-Dual KI-hSTING-R232 cells [1] .
T73746 DiABZI STING agonist-1
diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist, with EC 50 s of 130, 186 nM for human and mouse, respectively.
T74676 STING agonist-20-Ala-amide-PEG2-C2-NH2
STING agonist-20-Ala-amide-PEG2-C2-NH2 is an active scaffold comprising a stimulator of interferon genes (STING). STING agonist-20-Ala-amide-PEG2-C2-NH2 can be used to synthesize immune-stimulating antibody conjugate (IS...
T74677 STING agonist-20-Ala-amide-PEG2-C2-NH2 TFA
STING agonist-20-Ala-amide-PEG2-C2-NH2 (Compound 30b) TFA is an active scaffold comprising a stimulator of interferon genes ( STING ). STING agonist-20-Ala-amide-PEG2-C2-NH2 TFA can be used to synthesize immune-stimulati...
T9119 SU0268 Others
SU0268 is a potent and specific 8-Oxoguanine DNA glycosylase 1 (OGG1) inhibitor. SU0268 regulates inflammatory responses during Pseudomonas aeruginosa infection.
T7329 C-178 STING
C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells.
T13613 ChX710 STING
ChX710 could prime the type I interferon response to cytosolic DNA, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequence, and the phosphorylation of Interferon Regulatory Factor ...

Compounds

diABZI STING agonist-1 (Tautomerism)
T11035
Synonym: diABZI STING agonist (Compound 3)
Target: STING
STING agonist-4
T13015
Synonym:
Target: STING
STING activator Compound 53
T9853
Synonym:
Target: STING
STING agonist-1
T8328
Synonym: G10
Target: Virus Protease, STING
STING-IN-2
T9028
Synonym: C-170
Target: STING
STING-IN-3
T9029
Synonym: C-171
Target: STING
diABZI STING agonist-1 trihydrochloride
T5516
Synonym:
Target: STING
STING (WT/R232) activity regulator 126
T60000
Synonym:
Target: STING
STING Agonist C11
T38161
Synonym: STING Agonist C11
Target:
STING agonist-30
T74809
Synonym:
Target: STING
C-176
T5154
Synonym: C176,STING inhibitor 1
Target: STING
STING agonist-3 trihydrochloride
T13014L
Synonym: STING agonist-3 trihydrochloride (2138299-29-1 free base)
Target: Others
STING Agonist 12b
T38159
Synonym:
Target:
STING Agonist 1a
T38160
Synonym:
Target:
STING ligand-1
T13906
Synonym:
Target: Others
STING agonist-3
T13014
Synonym:
Target: Others
STING agonist-31
T75161
Synonym:
Target:
STING agonist-9
T74621
Synonym:
Target:
STING agonist-11
T63458
Synonym:
Target:
STING agonist-20
T72688
Synonym:
Target:
STING agonist-18
T81084
Synonym:
Target:
STING agonist-29
T75097
Synonym:
Target:
STING agonist-27
T75095
Synonym:
Target:
STING agonist-23
T75091
Synonym:
Target:
STING agonist-25
T75093
Synonym:
Target:
STING agonist-28
T75096
Synonym:
Target:
STING agonist-24
T75092
Synonym:
Target:
STING agonist-10
T63457
Synonym:
Target:
STING modulator-3
T72614
Synonym:
Target:
STING-IN-7
T81082
Synonym:
Target: STING
STING agonist-17
T74267
Synonym:
Target:
STING agonist-22
T75090
Synonym:
Target:
STING Agonist 12L
T83775
Synonym: Stimulator of Interferon Genes Agonist 12L
Target:
PROTAC STING Degrader-1
T74896
Synonym:
Target:
STING agonist-7
T61043
Synonym:
Target:
STING agonist-26
T75094
Synonym:
Target:
STING-IN-6
T74719
Synonym:
Target:
STING agonist-13
T74268
Synonym:
Target:
STING modulator-4
T72615
Synonym:
Target:
STING modulator-5
T74718
Synonym:
Target:
STING-IN-5
T75011
Synonym:
Target: STING
STING agonist-19
T81083
Synonym:
Target:
STING Agonist D61
T83841
Synonym: D61,Stimulator of Interferon Genes Agonist D61
Target:
STING agonist-8 dihydrochloride
T74328
Synonym:
Target:
diABZI STING agonist-1
T73746
Synonym:
Target:
STING agonist-20-Ala-amide-PEG2-C2-NH2
T74676
Synonym:
Target:
STING agonist-20-Ala-amide-PEG2-C2-NH2 TFA
T74677
Synonym:
Target:
SU0268
T9119
Synonym:
Target: Others
C-178
T7329
Synonym:
Target: STING
ChX710
T13613
Synonym:
Target: STING
1 2 3
Cat No. Product Name Synonyms Targets
T10909 Cyclic-di-GMP c-di-GMP,cyclic diguanylate,5GP-5GP Others
Cyclic-di-GMP is a STING agonist and ubiquitous second messenger, which regulates the formation, motility and virulence of biofilms in various bacterial species.
T72243 Cyclic-di-GMP diammonium 5GP-5GP diammonium,c-di-GMP diammonium ; cyclic diguanylate diammonium ; 5GP-5GP diammonium,c-di-GMP diammonium,cyclic diguanylate diammonium
Cyclic di-GMP (c-di-GMP) diammonium is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species .
T64248 Cyclic-di-GMP sodium
Cyclic di-GMP sodium (c-di-GMP sodium) is a STING activator and a ubiquitous second messenger that regulates biofilm formation, motility and virulence of various bacteria.
T73717 CGAMP diammonium
cGAMP (Cyclic GMP-AMPP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STIN...
T13606L CGAMP disodium
cGAMP disodium is a cyclic dinucleotide (CDN) found in bacteria that acts as an endogenous second messenger affecting interferon production in response to cytoplasmic DNA. cGAMP disodium cascades signals from type I inte...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-01206 Sting Protein, Human, Recombinant (Sumo & His) Human E. coli
Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a ...
TMPH-01645 MGP Protein, Human, Recombinant (His) Human E. coli
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery t...
TMPH-01653 MLANA Protein, Human, Recombinant (His) Human Yeast
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery t...
TMPH-01652 MLANA Protein, Human, Recombinant (B2M & His) Human E. coli
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery t...
TMPH-02079 SPTLC2 Protein, Human, Recombinant (His & SUMO) Human E. coli
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a...
TMPH-02078 Semenogelin-1/SEMG1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a...
TargetMol