T28072 |
MLN-3897
|
AVE-9897 , CCR1 antagonist 10 |
CCR
|
|
MLN-3897 is an orally active antagonist of CCR1 with a Ki of 2.3 nM for 125I-MIP-1α binding to THP-1 cell membranes. MLN... |
T9552 |
BAZ1A-IN-1
|
|
Epigenetic Reader Domain
|
|
BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good ant... |
T11492 |
GSK2983559 free acid
|
|
Others
,
RIP kinase
|
|
GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free a... |
T60012 |
HS-243
|
|
MAPK
,
IRAK
,
CDK
|
|
HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer ac... |
T17089 |
THP-SS-PEG1-Tos
|
|
Others
|
|
THP-SS-PEG1-Tos is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
T17088 |
THP-SS-PEG1-Boc
|
|
Others
|
|
THP-SS-PEG1-Boc is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
T17083 |
THP-PEG5-OH
|
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Others
|
|
THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
T38328 |
CU-32
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|
|
|
CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, ... |
T17085 |
THP-PEG8-OH
|
|
Others
|
|
THP-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
T18845 |
THP-PEG11-OH
|
|
Others
|
|
THP-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
T18847 |
THP-PEG4-Pyrrolidine(N-Me)-CH2OH
|
|
Others
|
|
THP-PEG4-Pyrrolidine(N-Me)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1[1]... |
T17084 |
THP-PEG6-OH
|
|
Others
|
|
THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. THP-PEG6-OH is also a non-clea... |
T17087 |
THP-SS-alcohol
|
|
Others
|
|
THP-SS-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
T17086 |
THP-PEG8-Tos
|
|
Others
|
|
THP-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
T17081 |
THP-PEG3-OH
|
|
Others
|
|
THP-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
T18846 |
THP-PEG4-Pyrrolidine(N-Boc)-CH2OH
|
|
Others
|
|
THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1[1... |
T9655 |
NBC 6
|
|
|
|
NLRP3-IN-NBC6 is a potent, selective NLRP3 inflammasome inhibitor ( IC 50 = 574 nM) that acts independently of Ca 2+. NL... |
TN5238 |
Viscidulin II
|
|
TNF
,
IL Receptor
|
|
Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppr... |
T35701 |
FSL-1 TFA
|
|
|
|
FSL-1 TFA, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infect... |
T38705 |
MS-PEG1-THP
|
|
|
|
MS-PEG1-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |