Search Result

Search Results for " tnf-α "

Targets

253

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T77494	TNF-α-IN-9		TNF
	TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.		TNF
T19584L	TNF-α (31-45), human acetate	TNF-α (31-45), human acetate(144796-71-4 free base)	Others
	TNF-α (31-45), human acetate is a peptide of tumor necrosis factor-α.		Others
T36127	TNF-α Antagonist
	TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact sit...
T40321	TNF-α-IN-6
	TNF-α-IN-6 is an orally efficacious allosteric inhibitor of TNFα ( K D = 6.8 nM).
T36097	TNF-α-IN-2
	TNF-α-IN-2 is a highly potent and orally bioavailable inhibitor of tumor necrosis factor alpha (TNFα), exhibiting an IC50 of 25 nM in the HTRF assay. It exerts its inhibitory effects by inducing conformational changes in...
T13175	TNF-α-IN-1		TNF
	TNF-α-IN-1 is a TNF-α inhibitor.		TNF
TP1626	TNF-α (46-65), human
	Human TNF alpha (46-65) peptide.
T19584	TNF-α (31-45), human		Others
	TNF-α (31-45), human is a peptide of tumor necrosis factor-α.		Others
TP1537	TNF-α (10-36), human
	TNF-α (10-36), human is a potent pro-inflammatory cytokine involved in the acute phase stress response.
T4637	R-7050	TNF-α Antagonist III	TNF
	R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.		TNF
TP1479	TNF-α (10-36), human (TFA) (144796-70-3 free base)	TNF-α (10-36), human (TFA)
	TNF-α (10-36), human (TFA) is a peptide of human TNF-α.
TP1636	TNF-α (31-45), human TFA (144796-71-4 free base)	TNF-α (31-45), human TFA
	TNF-α (31-45), human (TFA) is a peptide of tumor necrosis factor-α.
TP1669	TNF-α (46-65), human TFA (144796-72-5 free base)	TNF-α (46-65), human TFA
	TNF-α (46-65), human (TFA) is a peptide of human TNF-α.
T79025	TNF-α-IN-10
	TNF-α-IN-10 (compound 8a) acts as an inhibitor of IL-6 and TNF-α, demonstrating anti-inflammatory activity [1].
T78730	TNF-α-IN-11
	TNF-α-IN-11 (Compound 10) is a TNF-α inhibitor exhibiting a dissociation constant (K D) of 12.06 μM. By binding to TNF-α, it impedes TNF-α-induced caspase activation and the NF-κB signaling pathway. Additionally, it supp...
T80973	TNF-α-IN-8
	TNF-α-IN-8 (compound I-42) is an isoindole-imide-based inhibitor of tumor necrosis factor-alpha (TNF-α) with applications in researching various diseases including cancer, heart disease, osteoporosis, and autoimmune diso...
T8692	(Rac)-Benpyrine		TNF
	(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.		TNF
T8477	IQ-3		JNK
	IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α an...		JNK
T7495	Hexa-D-arginine		Others
	Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.		Others
T40423	L48H37
	L48H37 is a chemically stable analog of Curcumin. It exhibits potent inhibitory properties against myeloid differentiation protein 2 (MD2), acting as a specific inhibitor. Its mechanism involves inhibiting the interactio...
T2343	AS601245		JNK
	AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.		JNK
T8727	TH1020		TLR , Antibacterial
	TH1020 is a novel Inhibitor of Toll-Like Receptor 5 (TLR5)/Flagellin Complex with promising activity (IC50 =0.85±0.12 μm) and specificity.		TLR , Antibacterial
T76026	TNF-α (31-45), human TFA
	TNF-α (31-45), human (TFA) is a peptide of tumor necrosis factor-α. Tumour necrosis factor alpha (TNF alpha) is an inflammatory cytokine that induces necrosis or apoptosis [1] .
T76029	TNF-α (46-65), human TFA
	TNF-α (46-65), human (TFA) is a peptide of human TNF-α.
T13018	SU3327	halicin	JNK
	SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).		JNK
T8798	MSA-2		STING
	MSA-2 is a potent and orally available non-nucleotide STING agonist.		STING
T22115	SM-7368		NF-κB
	The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.		NF-κB
T4328	OSS_128167	SIRT6-IN-1	HBV , Sirtuin
	OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 μM), SIRT1(IC50=1578 μM) and SIRT2(IC50=751 μM).		HBV , Sirtuin
T6150	TAK-715		p38 MAPK , Casein Kinase , JNK
	TAK-715 is a p38 MAPK inhibitor for p38α.		p38 MAPK , Casein Kinase , JNK
T13324	VUF11207 fumarate		CXCR , Arrestin
	VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).		CXCR , Arrestin
T3185	R112	(E)-Elafibranor	Syk
	R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.		Syk
T22698	TLR3-IN-1	CU CPT 4a	TLR
	TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cell...		TLR
T1781	GW9508	GW 9508	GPR , Potassium Channel
	GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.		GPR , Potassium Channel
T6950	PNU-120596	NSC 216666	AChR
	PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.		AChR
T77778	KP-457	TNF‐α‐converting enzyme
	KP-457 (TNF-α-converting enzyme) is a selective inhibitor of ADAM17, with an IC50 value of 11.1 nM/L in cell-free assays. The compound can also cleave a variety of molecules, including GPIbα, GPV and TNF-α.
T6927	Pamapimod	R1503,Ro4402257	p38 MAPK , Autophagy
	Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectiv...		p38 MAPK , Autophagy
T4403	AX-024 hydrochloride	AX-024 HCl	IL Receptor , TNF , COX , IFNAR , Interleukin
	AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.		IL Receptor , TNF , COX , IFNAR , Interleukin
T8505	SC-236	Sc 236	Apoptosis , COX , PPAR
	SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).		Apoptosis , COX , PPAR
T2036	6-OAU	GTPL5846	GPR
	6-OAU (GTPL5846)(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.		GPR
T27695	JTE-607	JTE-607 dihydrochloride,JTE-607 HCl	Cysteine Protease
	JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.		Cysteine Protease
T3147	Pyrrolidinedithiocarbamate ammonium	PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate	NF-κB
	Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction.		NF-κB
T6823	E3330		HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
	E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.		HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
T4543	Telithromycin	HMR3647,Ketek,RU66647	Antibacterial , Antibiotic
	Telithromycin (HMR3647) is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity. Antibacterial Telithromycin prevents bacteria from growing, by interfering with their protein synthesis...		Antibacterial , Antibiotic
T14848	C 87		Others , TNF
	C 87 is a small-molecule TNF-α inhibitor. C 87 directly binds to TNFα, potently inhibits TNF-α-induced cytotoxicity (IC50 = 8.73 μM), and effectively blocks TNF-α-triggered signaling activities.		Others , TNF
T6204	QNZ	CAY10470,EVP4593	TNF , NF-κB
	QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.		TNF , NF-κB
T12985	SPD304 dihydrochloride		TNF
	SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.		TNF
T10730	CDC801	CDC-801	TNF , PDE
	CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 μM, respectively.		TNF , PDE
T4319	Hispidol	(Z)-Hispidol	TNF
	Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 μM.		TNF
T2384	Pomalidomide	CC-4047	Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
	Pomalidomide (CC-4047) inhibits TNF-α release in LPS stimulated human PBMCs (IC50: 13 nM). It is an anti-angiogenic agent and an immunomodulator.		Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
T2367	SKF-86002	SKF86002	p38 MAPK , TNF
	SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).		p38 MAPK , TNF

Compounds

TNF-α (31-45), human acetate

T19584L

Synonym: TNF-α (31-45), human acetate(144796-71-4 free base)

TNF-α (46-65), human

TP1626

Synonym:

Target:

TNF-α (31-45), human

T19584

Synonym:

Target: Others

TNF-α (10-36), human

Synonym: TNF-α Antagonist III

Target: TNF

TNF-α (10-36), human (TFA) (144796-70-3 free base)

TP1479

Synonym: TNF-α (10-36), human (TFA)

Target:

TNF-α (31-45), human TFA (144796-71-4 free base)

TP1636

Synonym: TNF-α (31-45), human TFA

Target:

TNF-α (46-65), human TFA (144796-72-5 free base)

TP1669

Synonym: TNF-α (46-65), human TFA

Target: TLR, Antibacterial

TNF-α (31-45), human TFA

T76026

Synonym:

Target:

TNF-α (46-65), human TFA

Target: p38 MAPK, Casein Kinase, JNK

VUF11207 fumarate

T13324

Synonym:

Target: CXCR, Arrestin

R112

T3185

Synonym: (E)-Elafibranor

Target: GPR, Potassium Channel

Synonym: TNF‐α‐converting enzyme

Target:

Pamapimod

T6927

Synonym: R1503,Ro4402257

Target: p38 MAPK, Autophagy

AX-024 hydrochloride

T4403

Synonym: AX-024 HCl

Target: IL Receptor, TNF, COX, IFNAR, Interleukin

SC-236

T8505

Synonym: Sc 236

Target: Apoptosis, COX, PPAR

Synonym: JTE-607 dihydrochloride,JTE-607 HCl

Target: Cysteine Protease

Pyrrolidinedithiocarbamate ammonium

T3147

Synonym: PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate

Target: HIF/HIF Prolyl-Hydroxylase, DNA/RNA Synthesis

Telithromycin

T4543

Synonym: HMR3647,Ketek,RU66647

Target: Antibacterial, Antibiotic

C 87

T14848

Synonym:

Target: Others, TNF

QNZ

T6204

Synonym: CAY10470,EVP4593

Target: TNF, NF-κB

SPD304 dihydrochloride

Synonym: (Z)-Hispidol

Target: Apoptosis, TNF, Ligand for E3 Ligase, Molecular Glues

SKF-86002

T2367

Synonym: SKF86002

Target: p38 MAPK, TNF

Cat No.	Product Name	Synonyms	Targets
T6S1572	Sauchinone		ERK , p38 MAPK , NF-κB
	1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...		ERK , p38 MAPK , NF-κB
T2893	Muscone	3-Methylcyclopentadecanone,Methylexaltone	MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin
	Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
T15686	L-741626	3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole	Dopamine Receptor
	L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively).		Dopamine Receptor
T2A2481	Taurochenodeoxycholic Acid	Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine	Apoptosis , TNF , Caspase , Endogenous Metabolite
	Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.		Apoptosis , TNF , Caspase , Endogenous Metabolite
T2P2870	Damascenone	trans-damascenone,Beta-Damascenone	Others , NF-κB , Endogenous Metabolite
	Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.		Others , NF-κB , Endogenous Metabolite
TN2130	Manghaslin	Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside	AChE , Glucosidase
	Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also shows inhibito...		AChE , Glucosidase
TN2215	Taurochenodeoxycholic acid sodium	Sodium taurochenodeoxycholate	Apoptosis , Endogenous Metabolite
	Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...		Apoptosis , Endogenous Metabolite
T13808	P-Coumaric Acid Ethyl Ester	Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate	Others , Drug Metabolite
	p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate) is the ethyl ester of p-Coumaric acid. p-Coumaric Acid is a common dietary polyphenol and also a potent immunosuppressive agent in treating autoimmune inflammato...		Others , Drug Metabolite
TCS2170	2,5-Dihydroxyacetophenone	Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP	ERK , NF-κB , Tyrosinase
	1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...		ERK , NF-κB , Tyrosinase
T5779	MOSLOFLAVONE		IL Receptor , Virus Protease , TNF , Antibacterial
	MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.		IL Receptor , Virus Protease , TNF , Antibacterial
TQ0218	Deoxyandrographolide	14-deoxyandrographolide	IL Receptor , TNF
	Deoxyandrographolide (14-deoxyandrographolide) potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory mediators TNF-α and IL-6.		IL Receptor , TNF
TN2539	1beta-Hydroxyalantolactone		IL Receptor , TNF
	1beta-Hydroxyalantolactone is a small molecular compound isolated from the flower head of the medicinal plant giant British flower, which can inhibit the expression of TNF-α, IL-17 and IFN-γ in cells, promote the secreti...		IL Receptor , TNF
T3889	Platycodin D		Prostaglandin Receptor , AMPK
	Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 1...		Prostaglandin Receptor , AMPK
TC0036	Compound Lup-20(29)-en-3-yl acetate		IL Receptor , VEGFR , Others , TNF , COX
	Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.		IL Receptor , VEGFR , Others , TNF , COX
T8288	14-Deoxyandrographolide		Apoptosis , Others
	14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.		Apoptosis , Others
T2720	Ginsenoside Rc	Panaxoside Rc	Others , TNF , GABA Receptor , Interleukin
	Ginsenoside Rc (Panaxoside Rc) is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.		Others , TNF , GABA Receptor , Interleukin
TN1520	Isoforskolin	Coleonol B	IL Receptor , TNF
	Isoforskolin is derived from Coleus forskohlii and reduces the secretion of TNF-α, IL-1β, IL-6 and IL-8 in human mononuclear leukocytes. Isoforskolin can be used in studies about the treatment of Lyme arthritis.		IL Receptor , TNF
T3887	Rosarin		Others
	Rosarin has anti-inflammatory and neuroprotective effects. Rosarin supresses the expression of the proinflammatory factors iNOS, IL-1 β, and TNF- α in the kidney and prefrontal cortex of brain in mice .		Others
T0131	Cepharanthine	NSC-623442	Apoptosis , TNF , HIV Protease , Autophagy
	Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production.		Apoptosis , TNF , HIV Protease , Autophagy
TN1507	Clematichinenoside AR		TNF , Autophagy
	Clematichinenoside AR exerts anti-inflammatory and immunosuppressive properties, it has anti-arthritic effects on PI3K/Akt signaling pathway and TNF-α± associated with collagen-induced arthritis.		TNF , Autophagy
TN1511	Cleomiscosin A		LDL , Antioxidant , TNF
	Cleomiscosin A is derived from Acer okamotoanum leaf and twig and shows inhibitory activity to TNF-α secretion of the mouse peritoneal macrophages. Cleomiscosin A can be used in studies about the prevention of LDL oxidat...		LDL , Antioxidant , TNF
T13864	Resolvin D1	RvD1	Apoptosis
	Resolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances macroph...		Apoptosis
T5785	MALTOTETRAOSE	Fujioligo 450,Amylotetraose,α-1,4-Tetraglucose	TNF , Endogenous Metabolite
	Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development.		TNF , Endogenous Metabolite
T3000	Magnolol	NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol	NF-κB , Retinoid Receptor , Antibacterial , PPAR , p53 , Autophagy
	Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
T2S0843	Negletein	7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor , TNF , NOS , Interleukin
	1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...		IL Receptor , TNF , NOS , Interleukin
TN6967	(R)-Isomucronulatol	(-)-Isomucronulatol,2H-1-Benzopyran-7-ol	Apoptosis
	(R)-Isomucronulatol (2H-1-Benzopyran-7-ol), a flavonoid that can be extracted from the leaves of Astragalus membranaceus, Sophora japonica, Sclerotium tigrinum, and Glycyrrhiza glabra, inhibits the proliferation and apop...		Apoptosis
T5754	Kavain		NF-κB , GABA Receptor
	Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors such as NF-kB and LITAF.		NF-κB , GABA Receptor
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
T2759	Loganin	Loganoside	Apoptosis , NF-κB , BACE , AChR , AChE
	Loganin (Loganoside), an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has displayed potent free-radical-scavenging activity and inhibitor...		Apoptosis , NF-κB , BACE , AChR , AChE
T3662	Eleutheroside E		NF-κB
	Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the ...		NF-κB
T3816	Velutin		NF-κB , HIF/HIF Prolyl-Hydroxylase
	Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK ...		NF-κB , HIF/HIF Prolyl-Hydroxylase
TN1410	Asperulosidic acid	ASPA	ERK , NF-κB
	Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-a...		ERK , NF-κB
T6S2099	Geraniin		Antioxidant , TNF
	1. Geraniin has a protective effect against OVX-induced rat osteoporosis. 2. Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo. 3. Geraniin exerts inhibitory effects on osteoclast differentiation ...		Antioxidant , TNF
T6S1579	Monotropein	Monotropeine	Others
	1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inf...		Others
TN6694	5,6-Benzoflavone	β-Naphthoflavone,beta-NF	Antioxidant
	5,6-Benzoflavone (β-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, which disrupts zinc homeostasis in human hepatocellular carcinoma HepG2 cells. 5,6-Benzoflavone (β-Naphthoflavone) possesses a...		Antioxidant
T5S0167	Atractylenolide I		IL Receptor , TNF , TLR , JAK , STAT
	1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide...		IL Receptor , TNF , TLR , JAK , STAT
T3763	Fumaric acid	Lichenic acid,Fumarate,2-Butenedioic acid,Trans-Butenedioic acid,Donitic acid,Allomaleic acid	Endogenous Metabolite
	Fumaric acid (2-Butenedioic acid) attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or a...		Endogenous Metabolite
T2768	Saikosaponin A		NF-κB , Antibacterial , Liver X Receptor
	Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropath...		NF-κB , Antibacterial , Liver X Receptor
T4973	Paraxanthine	1,7-DIMETHYLXANTHINE	Endogenous Metabolite
	Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is struc...		Endogenous Metabolite
T2932	Ginsenoside Rh1	Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1	IL Receptor , TNF , Endogenous Metabolite , PPAR , Interleukin
	Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
T2758	Madecassic acid	6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose	Others , TNF , COX , NO Synthase , Interleukin
	Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.		Others , TNF , COX , NO Synthase , Interleukin
T4S2063	Tetrahydrocoptisine	STYLOPINE	ERK , p38 MAPK , NF-κB
	1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may invo...		ERK , p38 MAPK , NF-κB
T6S0653	Linarin	Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine	TNF , AChE
	1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediat...		TNF , AChE
T2794	Astilbin	Neoastilbin,Taxifolin 3-O-rhamnoside,Isoastilbin,Taxifolin 3-rhamnoside,Neoisoastilbin	TNF , NF-κB , Nrf2
	Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.		TNF , NF-κB , Nrf2
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
T3240	Citronellol	dihydrogeraniol,(±)-β-Citronellol	Reactive Oxygen Species
	Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.		Reactive Oxygen Species
T6S1495	Ginsenoside Rk3		Others , NF-κB
	1. Ginsenoside Rk3 and Rh4 could have a role in treating inflammatory diseases. 2. Ginsenoside Rk3 is often used as a major ingredient of the compound preparation for ischemic heart diseases.		Others , NF-κB
T6S1049	Wilforine		ATPase
	Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be medi...		ATPase
T2S2264	Linalool	Linalol,(±)-Linalool,Phantol	Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
	1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
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Natural Products

Sauchinone

T6S1572

Synonym:

Target: ERK, p38 MAPK, NF-κB

Muscone

T2893

Synonym: 3-Methylcyclopentadecanone,Methylexaltone

Target: MMP, TNF, NF-κB, NOD-like Receptor (NLR), P-gp, Interleukin

L-741626

T15686

Synonym: 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole

Target: Dopamine Receptor

Taurochenodeoxycholic Acid

T2A2481

Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine

Target: Apoptosis, TNF, Caspase, Endogenous Metabolite

Damascenone

T2P2870

Synonym: trans-damascenone,Beta-Damascenone

Target: Others, NF-κB, Endogenous Metabolite

Manghaslin

TN2130

Synonym: Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside

Target: AChE, Glucosidase

Taurochenodeoxycholic acid sodium

TN2215

Synonym: Sodium taurochenodeoxycholate

Target: Apoptosis, Endogenous Metabolite

p-Coumaric Acid Ethyl Ester

T13808

Synonym: Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate

Target: Others, Drug Metabolite

2,5-Dihydroxyacetophenone

TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP

Target: ERK, NF-κB, Tyrosinase

MOSLOFLAVONE

T5779

Synonym:

Target: IL Receptor, Virus Protease, TNF, Antibacterial

Deoxyandrographolide

TQ0218

Synonym: 14-deoxyandrographolide

Target: IL Receptor, TNF

1beta-Hydroxyalantolactone

TN2539

Synonym:

Target: IL Receptor, TNF

Platycodin D

T3889

Synonym:

Target: Prostaglandin Receptor, AMPK

Compound Lup-20(29)-en-3-yl acetate

TC0036

Synonym:

Target: IL Receptor, VEGFR, Others, TNF, COX

14-Deoxyandrographolide

T8288

Synonym:

Target: Apoptosis, Others

Ginsenoside Rc

T2720

Synonym: Panaxoside Rc

Target: Others, TNF, GABA Receptor, Interleukin

Isoforskolin

TN1520

Synonym: Coleonol B

Target: IL Receptor, TNF

Target: Apoptosis, TNF, HIV Protease, Autophagy

Clematichinenoside AR

TN1507

Synonym:

Target: TNF, Autophagy

Cleomiscosin A

TN1511

Synonym:

Target: LDL, Antioxidant, TNF

Synonym: Fujioligo 450,Amylotetraose,α-1,4-Tetraglucose

Target: TNF, Endogenous Metabolite

Magnolol

T3000

Synonym: NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol

Target: NF-κB, Retinoid Receptor, Antibacterial, PPAR, p53, Autophagy

Negletein

T2S0843

Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

(R)-Isomucronulatol

TN6967

Synonym: (-)-Isomucronulatol,2H-1-Benzopyran-7-ol

Target: NF-κB, GABA Receptor

Mulberroside A

T6S1597

Synonym:

Target: TNF, Tyrosinase, Interleukin

Loganin

T2759

Synonym: Loganoside

Target: Apoptosis, NF-κB, BACE, AChR, AChE

Target: NF-κB, HIF/HIF Prolyl-Hydroxylase

Target: Antioxidant, TNF

Monotropein

T6S1579

Synonym: Monotropeine

Target: Others

5,6-Benzoflavone

TN6694

Synonym: β-Naphthoflavone,beta-NF

Target: IL Receptor, TNF, TLR, JAK, STAT

Fumaric acid

T3763

Synonym: Lichenic acid,Fumarate,2-Butenedioic acid,Trans-Butenedioic acid,Donitic acid,Allomaleic acid

Target: Endogenous Metabolite

Saikosaponin A

T2768

Synonym:

Target: NF-κB, Antibacterial, Liver X Receptor

Paraxanthine

T4973

Synonym: 1,7-DIMETHYLXANTHINE

Target: Endogenous Metabolite

Ginsenoside Rh1

T2932

Synonym: Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1

Target: IL Receptor, TNF, Endogenous Metabolite, PPAR, Interleukin

Madecassic acid

T2758

Synonym: 6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose

Target: Others, TNF, COX, NO Synthase, Interleukin

Tetrahydrocoptisine

T4S2063

Synonym: STYLOPINE

Target: ERK, p38 MAPK, NF-κB

Linarin

T6S0653

Synonym: Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine

Target: TNF, AChE

Astilbin

T2794

Synonym: Neoastilbin,Taxifolin 3-O-rhamnoside,Isoastilbin,Taxifolin 3-rhamnoside,Neoisoastilbin

Target: TNF, NF-κB, Nrf2

Polygalasaponin F

T3826

Synonym:

Target: NF-κB, TLR, Akt, PI3K

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

Citronellol

T3240

Synonym: dihydrogeraniol,(±)-β-Citronellol

Target: Reactive Oxygen Species

Ginsenoside Rk3

T6S1495

Synonym:

Target: Others, NF-κB

Synonym: Linalol,(±)-Linalool,Phantol

Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00779	TNF alpha Protein, Rabbit, Recombinant	Rabbit	E. coli
	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor ty...
TMPY-04146	TNF alpha Protein, Human, Recombinant (hFc)	Human	HEK293
	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-01294	TNF alpha Protein, Mouse, Recombinant	Mouse	E. coli
	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-00936	TNF alpha Protein, Human, Recombinant	Human	E. coli
	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-02202	TNF alpha Protein, Rat, Recombinant	Rat	E. coli
	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-02153	TNF beta Protein, Human, Recombinant	Human	E. coli
	Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho...
TMPK-00583	TNF alpha Protein, Ferret, Recombinant (His)	Ferret	E. coli
	Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system developm...
TMPK-00119	TNF alpha Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system developm...
TMPK-00121	TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system developm...
TMPK-00120	TNF alpha Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system developm...
TMPJ-00125	TNF alpha Protein, Human, Recombinant (aa 57-233, His)	Human	E. coli
	Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete li...
TMPJ-00124	TNF alpha Protein, Human, Recombinant (aa 77-233, His)	Human	E. coli
	Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete li...
TMPJ-00288	TNF RII Protein, Human, Recombinant (mFc)	Human	Human Cells
	Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58% and 56% amino a...
TMPY-05187	TNF alpha Protein, Mouse, Recombinant, Biotinylated	Mouse	E. coli
	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPJ-00287	TNF RII Protein, Human, Recombinant (hFc)	Human	Human Cells
	Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosis factor receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58% and 56% amino a...
TMPY-05237	TNF alpha Protein, Human, Recombinant, Biotinylated	Human	E. coli
	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-02069	TNF alpha Protein, Cynomolgus, Rhesus, Recombinant	Cynomolgus,Rhesus	E. coli
	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-05516	TNF alpha Protein, Cynomolgus, Recombinant, Biotinylated	Cynomolgus	E. coli
	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-02226	TNF alpha Protein, Ferret, Recombinant	Ferret	E. coli
	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-01594	TNF alpha Protein, Canine, Recombinant	Canine	E. coli
	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPJ-00546	EFNA1 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can ...
TMPY-01750	HVEM Protein, Human, Recombinant (His)	Human	HEK293
	Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPY-01774	TREM-1 Protein, Human, Recombinant (His)	Human	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-01928	IL-18 Protein, Rhesus, Recombinant (His)	Rhesus	E. coli
	Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g...
TMPY-03273	IL-18 Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g...
TMPY-00277	IL-18 Protein, Human, Recombinant	Human	E. coli
	Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g...
TMPY-05053	ANGPTL2 Protein, Human, Recombinant (His)	Human	HEK293
	The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPJ-00618	TNF RII Protein, Rhesus macaque, Recombinant (hFc)	Rhesus Macaque	Human Cells
	Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains:...
TMPJ-00619	TNF RII Protein, Rhesus macaque, Recombinant (His)	Rhesus Macaque	Human Cells
	Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains:...
TMPJ-00296	TNF RII Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	Human Cells
	Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains:...
TMPK-00564	TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of...
TMPJ-00968	NAMPT Protein, Human, Recombinant (His)	Human	E. coli
	Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular e...
TMPK-01216	SEMA7A Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic ra...
TMPY-05293	HVEM Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Baculovirus-Insect Cells
	Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPY-05515	HVEM Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPY-04253	HVEM Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPY-06941	HVEM Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPY-05417	HVEM Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPY-05380	HVEM Protein, Human, Recombinant (hFc)	Human	HEK293
	Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPK-00741	SEMA7A Protein, Human, Recombinant (His)	Human	HEK293
	Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic ra...
TMPY-02549	GBP1 Protein, Human, Recombinant (His)	Human	HEK293
	Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 ex...
TMPY-05512	HVEM Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPY-01425	HVEM Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293
	Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPJ-00177	BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated	Human	Human Cells
	B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), T...
TMPY-03308	ADAM17 Protein, Rat, Recombinant (His)	Rat	HEK293
	ADAM17 is a member of the ADAM protein family of disintegrins and metalloproteases. ADAM17 is ubiquitously expressed in the human colon, with increased activity in the colonic mucosa of patients with ulcerative coliti...
TMPJ-01105	MPF Protein, Human, Recombinant (His)	Human	Human Cells
	Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Me...
TMPJ-01104	MPF Protein, Human, Recombinant (hFc)	Human	Human Cells
	Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Me...
TMPJ-00680	ANGPTL7 Protein, Human, Recombinant (His)	Human	Human Cells
	Angiopoietin-like 7 (ANGPTL7) is a secreted glycoprotein that is structurally related to the angiopoietins. Members of this protein family contain an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain....
TMPY-03861	Amelotin Protein, Human, Recombinant (mFc)	Human	HEK293
	Amelotin (AMTN) is a tooth enamel protein which is expressed in maturation-stage ameloblasts and also in the internal basal lamina of junctional epithelium, a unique epithelial structure attached to the tooth surface whi...
TMPJ-01370	EDAR Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Ectodysplasin A receptor (EDAR) is a type I transmembrane protein of the TNF-α receptor superfamily which plays a key role in ectodermal differentiation. EDAR was encoded by the mouse downless gene and defective in human...
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TNF alpha Protein, Rabbit, Recombinant

TMPJ-00779

Species: Rabbit

Expression System: E. coli

TNF alpha Protein, Human, Recombinant (hFc)

TMPY-04146

Species: Human

Expression System: HEK293

TNF alpha Protein, Mouse, Recombinant

TMPY-01294

Species: Mouse

Expression System: E. coli

TNF alpha Protein, Human, Recombinant

TMPY-00936

Species: Human

Expression System: E. coli

TNF alpha Protein, Rat, Recombinant

TMPY-02202

Species: Rat

Expression System: E. coli

TNF beta Protein, Human, Recombinant

TMPY-02153

Species: Human

Expression System: E. coli

TNF alpha Protein, Ferret, Recombinant (His)

TMPK-00583

Species: Ferret

Expression System: E. coli

TNF alpha Protein, Cynomolgus, Recombinant (His)

TMPK-00119

Species: Cynomolgus

Expression System: HEK293

TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00121

Species: Human

Expression System: HEK293

TNF alpha Protein, Human, Recombinant (His & Avi)

TMPK-00120

Species: Human

Expression System: HEK293

TNF alpha Protein, Human, Recombinant (aa 57-233, His)

TMPJ-00125

Species: Human

Expression System: E. coli

TNF alpha Protein, Human, Recombinant (aa 77-233, His)

TMPJ-00124

Species: Human

Expression System: E. coli

TNF RII Protein, Human, Recombinant (mFc)

TMPJ-00288

Species: Human

Expression System: Human Cells

TNF alpha Protein, Mouse, Recombinant, Biotinylated

TMPY-05187

Species: Mouse

Expression System: E. coli

TNF RII Protein, Human, Recombinant (hFc)

TMPJ-00287

Species: Human

Expression System: Human Cells

TNF alpha Protein, Human, Recombinant, Biotinylated

TMPY-05237

Species: Human

Expression System: E. coli

TNF alpha Protein, Cynomolgus, Rhesus, Recombinant

TMPY-02069

Species: Cynomolgus,Rhesus

Expression System: E. coli

TNF alpha Protein, Cynomolgus, Recombinant, Biotinylated

TMPY-05516

Species: Cynomolgus

Expression System: E. coli

TNF alpha Protein, Ferret, Recombinant

TMPY-02226

Species: Ferret

Expression System: E. coli

TNF alpha Protein, Canine, Recombinant

TMPY-01594

Species: Canine

Expression System: E. coli

EFNA1 Protein, Human, Recombinant (hFc)

TMPJ-00546

Species: Human

Expression System: Human Cells

HVEM Protein, Human, Recombinant (His)

TMPY-01750

Species: Human

Expression System: HEK293

TREM-1 Protein, Human, Recombinant (His)

TMPY-01774

Species: Human

Expression System: HEK293

IL-18 Protein, Rhesus, Recombinant (His)

TMPY-01928

Species: Rhesus

Expression System: E. coli

IL-18 Protein, Mouse, Recombinant

TMPY-03273

Species: Mouse

Expression System: E. coli

IL-18 Protein, Human, Recombinant

TMPY-00277

Species: Human

Expression System: E. coli

ANGPTL2 Protein, Human, Recombinant (His)

TMPY-05053

Species: Human

Expression System: HEK293

TNF RII Protein, Rhesus macaque, Recombinant (hFc)

TMPJ-00618

Species: Rhesus Macaque

Expression System: Human Cells

TNF RII Protein, Rhesus macaque, Recombinant (His)

TMPJ-00619

Species: Rhesus Macaque

Expression System: Human Cells

TNF RII Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPJ-00296

Species: Mouse

Expression System: Human Cells

TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)

TMPK-00564

Species: Cynomolgus

Expression System: HEK293

NAMPT Protein, Human, Recombinant (His)

TMPJ-00968

Species: Human

Expression System: E. coli

SEMA7A Protein, Mouse, Recombinant (His)

TMPK-01216

Species: Mouse

Expression System: HEK293

HVEM Protein, Cynomolgus, Recombinant (His)

TMPY-05293

Species: Cynomolgus

Expression System: Baculovirus-Insect Cells

HVEM Protein, Human, Recombinant (His), Biotinylated

TMPY-05515

Species: Human

Expression System: HEK293

HVEM Protein, Cynomolgus, Recombinant (hFc)

TMPY-04253

Species: Cynomolgus

Expression System: HEK293

HVEM Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06941

Species: Human

Expression System: HEK293

HVEM Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPY-05417

Species: Human

Expression System: HEK293

HVEM Protein, Human, Recombinant (hFc)

TMPY-05380

Species: Human

Expression System: HEK293

SEMA7A Protein, Human, Recombinant (His)

TMPK-00741

Species: Human

Expression System: HEK293

GBP1 Protein, Human, Recombinant (His)

TMPY-02549

Species: Human

Expression System: HEK293

HVEM Protein, Mouse, Recombinant (His)

TMPY-05512

Species: Mouse

Expression System: HEK293

HVEM Protein, Mouse, Recombinant (His & hFc)

TMPY-01425

Species: Mouse

Expression System: HEK293

BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated

TMPJ-00177

Species: Human

Expression System: Human Cells

ADAM17 Protein, Rat, Recombinant (His)

TMPY-03308

Species: Rat

Expression System: HEK293

MPF Protein, Human, Recombinant (His)

TMPJ-01105

Species: Human

Expression System: Human Cells

MPF Protein, Human, Recombinant (hFc)

TMPJ-01104

Species: Human

Expression System: Human Cells

ANGPTL7 Protein, Human, Recombinant (His)

TMPJ-00680

Species: Human

Expression System: Human Cells

Amelotin Protein, Human, Recombinant (mFc)

TMPY-03861

Species: Human

Expression System: HEK293

EDAR Protein, Mouse, Recombinant (hFc)

TMPJ-01370

Species: Mouse

Expression System: Human Cells

--------- More ---------

Cat No.	Product Name
L4700	Immunology/Inflammation Compound Library	4720 compounds
	A unique collection of 4720 anti-inflammation compounds effective for high throughput screening and high content screening.
L3800	NF-κB Signaling Compound Library	740 compounds
	A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L9840	Anti-Alzheimer's Disease Compound Library	1040 compounds
	A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.

Libraries

Immunology/Inflammation Compound Library

L4700

Compounds: 4720

NF-κB Signaling Compound Library

L3800

Compounds: 740

Anti-Alzheimer's Disease Compound Library

L9840

Compounds: 1040