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Search Results for " taspine "

2

Compounds

1

Natural Products

Cat No. Product Name Synonyms Targets
T28960 Thaspine HCl Thaspine,Thaspine HCl, NSC 135784,NSC-135784,NSC135784
Thaspine is a potent topoisomerase IB inhibitor. Taspine downregulates VEGF expression and inhibits proliferation of vascular endothelial cells through PI3 kinase and MAP kinase signaling pathways.
T20656 Verapamil NSC 135784,NSC-135784,CP-16533-1,(±)-Verapamil P450 , Calcium Channel , P-gp
Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies about the treatment of high blood pressure, heart arrhythmias...
Cat No. Product Name Synonyms Targets
TN5100 Taspine ERK , EGFR , BCL , VEGFR , MAPK , Akt
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful an...
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