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Cat No. | Product Name | Synonyms | Targets |
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T73617 | Urate oxidase | ||
Urate oxidase (Uox), also known as uricase, is a peroxisomal enzyme widely utilized in biochemical research. It catalyzes the conversion of uric acid to allantoin in the majority of mammals [1]. | |||
T15160 | Dotinurad | (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone | OAT |
Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid). | |||
T3994 | Verinurad | RDEA3170 | OAT |
Verinurad (RDEA3170) (RDEA3170) is an organic anion transporter URAT1 (SLC22A12) inhibitor for the treatment of gout and hyperuricemia. | |||
T20545 | Benzarone | Benzarona,Vasoc,Venagil,Benzaronum | OAT |
Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum. | |||
T6875 | Lesinurad | RDEA594 | OAT |
Lesinurad (RDEA594) is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited clinical use but has not been associated with seru... | |||
T22443 | Triglycidyl isocyanurate | Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI | Apoptosis |
Triglycidyl isocyanurate (Teroxirone) is a triazene triepoxide with antineoplastic and antiangiogenic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl isocyanurate alk... | |||
T8365 | Methenamine Hippurate | Antibacterial | |
Methenamine Hippurate is a component of Hiprex, with antibacterial activity. | |||
T1145 | Diminazene Aceturate | Others , Serine Protease , Parasite | |
Diminazene is a trypanocidal agent. | |||
T1526 | Nifuratel | NF 113,SAP 113,Methylmercadone | Antibacterial , Antibiotic , Parasite |
Nifuratel (SAP 113) is a local antiprotozoal and antifungal agent that may also be given orally. | |||
T5039 | Aminohippurate sodium | Sodium 4-aminohippurate Hydrate,Sodium p-aminohippurate,p-Aminohippuric acid sodium salt | Others |
Aminohippurate sodium (Sodium p-aminohippurate) is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. | |||
T38612 | Linaprazan glurate | Others | |
Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate can be used in studies about gastrointestinal inflammatory diseases and peptic ulcer diseases. | |||
T34813 | Testosterone ketolaurate | Testosterone 3-oxododecanoate,Testosteroni ketolauras | |
Testosterone ketolaurate is an androgen and anabolic steroid and a testosterone ester. | |||
T20215 | Acetaminophen mercapturate | ||
Paracetamol Mercapturate is a metabolite of Acetaminophen. It can also be used in the biological study of urinary antihypertensive drugs. | |||
T17286 | Zaurategrast | CT7758 | Others |
Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin. | |||
T25931 | Pentachlorophenyl laurate | NSC-77542,Mystox LPL,NSC 77542,NSC77542 | |
Pentachlorophenyl laurate is used as a pesticide. | |||
T33907 | PEG-9 Laurate | NSC 1249,Lipal 4L,NSC-1249,Lipal 4ML,NGML | |
PEG-9 Laurate is a bioactive chemical. | |||
T30976 | Clofibrate mercapturate | ||
Clofibrate mercapturate is a urinary metabolite of clofibrate. | |||
T32080 | Histidine oxoglurate | Histidine alpha-ketoglutarate | |
Histidine oxoglurate is a bioactive chemical. | |||
T31683 | Estrofurate | AY-11,483,AY-11483,AY 11483-16 | |
Estrofurate is a biochemical. | |||
T33785 | O-Iodohippurate sodium | Hippodin,NSC-63351,Sodium iodohippurate NSC 63351,NSC63351 | |
o-Iodohippurate sodium is an analogue of p-aminohippuric acid used to determine effective renal plasma flow. Labelled OIH has a higher clearance than other radiopharmaceutical yet developed and is extremely suitable for ... | |||
T30003 | Ammonium acryloyldimethyltaurate | ||
Ammonium acryloyldimethyltaurate is a bioactive chemical. | |||
T13388L | Zaurategrast ethyl ester | UCB1184197,CDP323 | Others |
Zaurategrast ethyl ester is the ethyl ester prodrug of CT7758 and is an α4β1/α4β7 integrin antagonist. It is used for the treatment of inflammatory and autoimmune disorders. | |||
T13388 | Zaurategrast ethyl ester sulfate | UCB1184197 sulfate,CDP323 sulfate | Others |
Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders. | |||
T33881 | Paracetamol mercapturate | ||
Paracetamol mercapturate is a deuterated metabolite of acetaminophen. | |||
T40438 | PEG-8 laurate | ||
PEG-8 laurate is a monofunctional surfactant and skin penetration enhancer. It disrupts the skin barrier and facilitates the formation of elastic vesicles when synthesized. | |||
T36469 | Atrazine Mercapturate | ||
Atrazine mercapturate is a major, glutathione-derived metabolite of atrazine , an herbicide that is effective in controlling a broad range of weeds. Atrazine has been reported to cause cancer in certain laboratory animal... | |||
T20598 | Sorbitan monolaurate | Emasol L 10,Emasol L-10,Arlacel20,Arlacel-20,Arlacel 20,Emasol L10 | |
Sorbitan monolaurate, a non-ionic surfactant, is widely used as a stabilizer and emulsifier in pharmaceutical formulations, food, and cosmetic industries. | |||
T61048 | Puliginurad | YL-90148 | OAT |
Puliginurad (YL-90148) is a potent and selective inhibitor of urate transporter protein (URAT) with inhibitory effects on uric acid reabsorption.Puliginurad can be used for the prevention and treatment of hyperuricemia a... | |||
T0435 | Sulfinpyrazone | (+/-)-Sulfinpyrazone,G-28315,NSC 75925 | COX |
Sulfinpyrazone (NSC-75925) is a uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties. | |||
T68298 | Oteracil | ||
Oteracil is an antagonist of urate oxidase. | |||
T62593 | Xininurad | ||
Xininurad (XNW3009) is a urate transporter (URAT) inhibitor. | |||
T72632 | URAT1 inhibitor 4 | ||
URAT1 Inhibitor 4, derived from Lesinurad, is a potent, orally active inhibitor of URAT1 with an IC50 value of 7.56 μM, demonstrating greater in vivo urate-lowering efficacy than Lesinurad [1]. | |||
T60724 | URAT1 inhibitor 3 | ||
URAT1 inhibitor 3 is a potent, orally active, selective inhibitor of URAT1(IC 50 = 0.8 nM). URAT1 inhibitor 3 shows urate-lowering efficacy that can be used in gout and hyperuricemi research [1]. | |||
T27275 | Epaminurad | ||
Epaminurad (UR-1102) is an orally active, potent and selective URAT1 (urate transporter 1) inhibitor, with a Ki of 0.057 μM. Epaminurad inhibits OAT1 and OAT3 (organic anion transporter) quite modestly. Epaminurad is a u... | |||
T79177 | URAT1&XO inhibitor 2 | Xanthine Oxidase | |
Compound BDEO (URAT1&XO inhibitor 2) serves as a dual-action inhibitor targeting both xanthine oxidase (XO) and URAT1, demonstrating an IC50 value of 3.3 μM for XO inhibition. It effectively impedes uric acid uptake in H... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0626 | Uric Acid | 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate | Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase |
Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ... | |||
T41242 | Uric acid sodium | Reactive Oxygen Species | |
Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric acid sodium, which removes reactive oxygen species (ROS) suc... | |||
TN6895 | Methyl Laurate | methyl dodecanoate | Others |
Methyl Laurate (methyl dodecanoate) is a 12-carbon saturated fatty acid and an esterified version of lauric acid[1]. | |||
T30004 | Ammonium laurate | AI3 00287,AI3-00287,AI300287 | |
Ammonium laurate is a surfactant. |
Cat No. | Product Name | Species | Expression System |
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TMPH-02123 | SLC2A9 Protein, Human, Recombinant (His) | Human | in vitro E. coli expression system |
Urate transporter, which may play a role in the urate reabsorption by proximal tubules. Does not transport glucose, fructose or galactose. | |||
TMPH-01364 | Galectin-9/LGALS9 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Binds galactosides. Has high affinity for the Forssman pentasaccharide. Ligand for HAVCR2/TIM3. Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death. Also stimulates bactericidal activity in infected macropha... | |||
TMPH-01739 | NLRP3 Protein, Human, Recombinant (His) | Human | E. coli |
As the sensor component of the NLRP3 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, initiates the formation of the inflammasome polym... |