ACH-000143 have been identified as a novel agonist of the melatonin receptors MT1 and MT2.

Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.

ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.

ACH-702 is an agent of anti-tubercular. ACH-702 is an effective, bactericidal compound with activity against many antibiotic-resistant pathogens.

Acetylcholine Chloride is the chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride (Pilofrin) mimics the parasympathomimetic effect of the endogenous compound acetylcholine. Administered as an ophthalmic solution, this drug stimulates the cholinoceptors in the sphincter muscle of the iris, causing the pupil to constrict.

Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus.

Sulfachloropyridazine (Sulfachlorpyridazine) is a sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

Stachyose tetrahydrate (D-Stachyose tetrahydrate) is a tetrasaccharide consisting of two α-D-galactose units, one α-D-glucose unit, and one β-D-fructose unit sequentially.

Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma.

AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1 μM, respectively. 1 had a neuroprotective effect and was not significantly cytotoxic.

Trachelanthine is a natural product from Eupatorium fortunei.

Urechistachykinin II acetate (Uru-TK II acetate) is an invertebrate rapid kinin-related peptide (TRPs) isolated from carotenoid worms, shows antimicrobial activities without a hemolytic effect

Dipotassium tetrachloroplatinate (Potassium tetrachloroplatinate) exhibits antitumor activity in solid tumor lines and can be used in the treatment of oncological diseases. Dipotassium tetrachloroplatinate also acts as a radiosensitizer and enhances the killing effect of thermotherapy.

2-(Chloromethyl)-4-(4-nitrophenyl)thiazole is a natural product derived from Astragalus propinquus.2-(Chloromethyl)-4-(4-nitrophenyl)thiazole exhibits anticancer activity. 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole possesses anticancer activity and has been shown to be active in hepatocellular carcinoma (HCC) by inhibiting the M2 polarization of tumor-associated macrophages (TAM).

Metolachlor is an organic compound. Metolachlor is also widely used as an herbicide.

Urechistachykinin I acetate(149097-03-0 free base) (Uru-TK I acetate) is an invertebrate kalinin-related peptide (TRPs) isolated from thylakoid nematodes.

Torachrysone tetraglucoside is a phenolic glycoside isolated from the leguminous plant cassia with antioxidant and antimicrobial activities.

Torachrysone Triglucoside is a glucoside isolated from cassia seeds with potential antitumor activity.

ACHE-IN-38 is a potent Acetylcholinesterase inhibitor that can be used for the synthesis of compounds with anti-inflammatory, anti-tumor, and antibacterial activities.

ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.

gamma-preprotachykinin amide (72-92) acetate is a 21 amino acid peptide belonging to the tachykinin (TK) family and including neurokinin A (NKA) in its C-terminal sequence. gamma-preprotachykinin amide (72-92) acetate possesses higher affinity than NKA for central NK-2 receptors; it shows lower affinity for NK-1 receptors, however, it potently stimulates salivary secretion, which is mediated by NK-1 receptor activation.

Torachrysone gentiobioside is a phenolic glycoside isolated from cassia seeds.

Locustatachykinin I acetate is a substrate for a deamidase in Lacanobia. Locustatachykinin I acetate is an insect tachykinin-related peptide isolated from Locusta migratoria.

ACHN-975 TFA is a selective LpxC inhibitor with a subnanomolar inhibitory. It is against a wide range of gram-negative bacterias with low MIC values (≤1 μg/mL).

ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.

Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the complement replacement pathway (APC) and may block the complement replacement pathway in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).

Vemircopan is a complement factor D inhibitor.

Elvucitabine, a reverse transcriptase inhibitor, is used potentially for the treatment of HBV infection and HIV infection.

Arachidonic acid (Immunocytophyte) is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.

Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and elevates levels of acetylcholine (ACh) in the hippocampus and frontal cortex, PA also significantly ameliorates neuroinflammation and oxidative stress in mice; suggest that PA might exert a significant neuroprotective effect on cognitive impairment, driven in part by the modulation of cholinergic activity and neuroinflammation. Polygalacic acid shows significant postingestive effects on Spodoptera littoralis larvae.

Epinortrachelogenin is a natural product of Cephalotaxus, Cephalotaxaceae. The catalog number is TN3974 and the CAS number is 125072-69-7. Epinortrachelogenin can be used as a reference standard.

Stachybotrolide is a natural product from Stachybotrys alternans.

Achyranthoside C is a natural product for research related to life sciences. The catalog number is TN3345 and the CAS number is 168009-90-3.

Cassiachromone has antiplasmodial activity

Torachrysone-8-O-b-D-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes.

Nortrachelogenin 4'-O-β-gentiobioside (compound 20) is a lignan extracted from the aerial components of Trachelospermum [1].

Lachnone A, a chromone derivative, has been isolated from the filamentous fungus Lachnum sp. BCC 2424 [1].

Omega-3 Arachidonic Acid ethyl ester, a rare polyunsaturated fatty acid with limited presence in dietary sources, is crucial for infant growth and development and offers protection against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune disorders. In human platelet membranes, it impedes arachidonyl-CoA synthetase, exhibiting a Ki of 14 μM, and shows similar inhibitory effects on arachidonoyl-CoA synthetase in calf brain extract with an IC50 of roughly 5 μM. The ethyl arachidonate derivative offers enhanced lipophilicity compared to its free acid counterpart.

Locustatachykinin II (Lom-TK II), an insect neuropeptide analogous to the vertebrate tachykinin family, serves as a research tool for investigating insect endocrine systems [1].

AChE-IN-43 is a potent, selective AChE inhibitor with a K i of 0.41 μM, applicable in the study of neurological diseases [1].

Compound AChE-IN-42, also known as Compound 28, is an acetylcholinesterase (AChE) inhibitor with an inhibition constant (K i) of 0.44 μM [1].

5-Methoxytracheloside, a lignan lactone, is isolated from the stems and leaves of Trachelospermum jasminoides [1].

2,3,4,5-Tetrachlorophenol is a metabolite of the insecticide γ-lindane.1It is toxic to fathead minnows and rainbow trout (LC50s = 0.496 and 0.304 mg/L, respectively, in tank water).2 1.Chadwick, R.W., and Freal, J.J.The identification of five unreported lindane metabolites recovered from rat urineBull. Environ. Contam. Toxicol.7(2)137-146(1972) 2.Holcombe, G.W., Phipps, G.L., Knuth, L., et al.The acute toxicity of selected substituted phenols, benzenes and benzoic acid esters to fathead minnows Pimephales promelasEnviron. Pollut.35(4)367-381(1984)

Homocysteinylpropachlor is a bioactive chemical.

Azadirachtin B, a limonoid derived from the seed kernels of Azadirachta indica, exhibits a broad spectrum of biochemical activities, including insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral, and osteogenic effects. It is effective against the Epstein-Barr virus early antigen (EBV-EA), enhances alkaline phosphatase (ALP) activity, and promotes osteoblast differentiation[1][2][3].

1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol . 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM. It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS. It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol is an intrinsic metabolite and a component of the cell membrane [1].

AChE-IN-3 had inhibitory effect on AChE and stronger inhibitory effect on NO, with EC50 of 0.57 μM.

Tetrachloroglycoluril is a biochemical substance.

Torachrysone shows promising antioxidant activity. Torachrysone, toralactone , aloe-emodin, rhein and emodin show noticeable antibacterial effects on four strains of methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration of 2-