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Search Results for " bcl "

205

Compounds

66

Natural Products

44

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T38622 Bcl-xL antagonist 2 BCL
Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer cells and can be used in studies about chronic lymphocytic l...
T77571 Bcl-B inhibitor 1 Apoptosis , BCL
Bcl-B inhibitor 1 is a Bcl-B inhibitor with antitumor activity that binds to and inactivates pro-apoptotic proteins in the BH3 structural domain.
T10483 Lisaftoclax Bcl-2/Bcl-xl inhibitor 1,APG-2575 BCL
Lisaftoclax (Bcl-2/Bcl-xl inhibitor 1) is an oral dual inhibitor of Bcl-2 and Bcl-xl, with IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively. Lisaftoclax is used to treat chronic lymphocytic leukemia (CLL...
T39961 Bcl-2-IN-2
Bcl-2-IN-2 is a highly potent and selective inhibitor targeting Bcl-2 and Bcl-xL. It displays an IC50 value of 0.034 nM, suggesting its strong inhibitory activity specifically against Bcl-2. Additionally, Bcl-2-IN-2 exhi...
T11969 MCL-1/BCL-2-IN-2 Others
MCL-1/BCL-2-IN-2 is a potent and selective Bcl-2 and Mcl-1 dual inhibitor.
T11970 MCL-1/BCL-2-IN-3 Others
MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.
T11971 MCL-1/BCL-2-IN-4 Others
MCL-1/BCL-2-IN-4 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor.
T11968 MCL-1/BCL-2-IN-1 BCL
MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective dual inhibitor of Mcl-1 and Bcl-2 with IC 50 s of 4.45 and 3.18 μM, respectively [1].
T79171 Bcl-2-IN-11
Bcl-2-IN-11 (compound 6) is a potent and selective inhibitor of Bcl-2 activity, exhibiting an IC50 of 0.9 nM, and demonstrates minimal inhibition against Bcl-xl (IC50 > 1000 nM). This compound is utilized in researching ...
T74297 Bcl-2-IN-4
Bcl-2-IN-4 is a potent, orally active and selective Bcl-2 inhibitor with an IC 50 of 1.5 nM. Bcl-2-IN-4 displays >200-fold selectivity over Bcl-xL (IC 50 of 411 nM). Bcl-2-IN-4 inhibits RS4; 11 cell proliferation with an...
T82912 Bcl-2-IN-14
Bcl-2-IN-14 (Compound 13c), a BCL-2 inhibitor, exhibits an inhibitory concentration (IC 50) of 0.471 μM, and is applicable in cancer research [1].
T63676 Bcl-2-IN-6
Bcl-2-IN-6 is a potent inhibitor of Bcl-2 (b-cell lymphoma-2) that downregulates Bcl-2 expression and increases the expression of p53, Bax, and caspase-7 mRNA. bcl-2-IN-7 induces cell cycle arrest and apoptosis in breast...
T82910 Bcl-2-IN-16
Bcl-2-IN-16 is a Bcl-2 (B-cell lymphoma 2) inhibitor [1].
T64053 Bcl-2-IN-8
Bcl-2-IN-8 is a potent anti-cancer agent. bcl-2-IN-8 exhibits anti-proliferative effects on both drug-sensitive and drug-resistant cancer cells. bcl-2-IN-8 inhibits cell migration in a dose-dependent manner. bcl-2-IN-8 b...
T80221 TAT-BH4 (Bcl-xL) Apoptosis
TAT-BH4 (Bcl-xL), primarily localized at the mitochondria, inhibits apoptotic cell death. This compound comprises an N-terminal eosin-labeled cysteine and the protein transduction domain of the HIV TAT protein (amino aci...
T74138 PROTAC Bcl-xL degrader-2
PROTAC Bcl-xL degrader-2 is a potent Bcl-xL ( Bcl-2 family member) degrader based on von Hippel-Lindau ligand, with an IC 50 of 0.6 nM.
T73999 PROTAC Bcl-xL degrader-3
PROTAC Bcl-xL degrader-3 is a potent ROTAC Bcl-xL degrader.
T80222 TAT-BH4 (Bcl-xL) (TFA) Apoptosis
"TAT-BH4 (Bcl-xL) TFA, primarily localized at the mitochondria, inhibits apoptotic cell death. This compound comprises an eosin-labeled cysteine at the N-terminal and the protein transduction domain from the HIV TAT prot...
T74298 Bcl-2-IN-5
Bcl-2-IN-5 is a BCL-2 inhibitor with IC 50 s of 0.12 nM, 0.14 nM and 0.22 nM for Bcl-2 wild type, Bcl-2 D103Y and Bcl-2 G101V , respectively. Bcl-2-IN-5 inhibits the cell growth with IC 50 values of 0.2 nM and 0.44 nM fo...
T63757 Bcl-2-IN-9
Bcl-2-IN-9 is a novel, pro-apoptotic, low cytotoxic Bcl-2 inhibitor (IC50: 2.9 μM). Bcl-2-IN-9 downregulates Bcl-2 expression, induces apoptosis in cancer cells, and exhibits high selectivity for leukemia cells.
T82914 Bcl-2-IN-12
Bcl-2-IN-12 (Compound 1) is a potent Bcl-2 inhibitor with an IC50 value of 6 nM, utilized in cancer research [1].
T82913 Bcl-2-IN-13
Bcl-2-IN-13 is a potent inhibitor of Bcl-2, exhibiting an IC50 of 17 nM, and holds potential for use in cancer research [1].
T82911 Bcl-2-IN-15
Bcl-2-IN-15 (Compound 13d) is a Bcl-2 inhibitor with an IC50 of 363 nM, which impedes the proliferation of the NCI leukemia cancer cell line [1].
T63521 Bcl-2-IN-7
Bcl-2-IN-7 is a potent inhibitor of Bcl-2 (b-cell lymphoma-2), which can downregulate the expression of Bcl-2, increase the expression of p53, Bax, caspase-7 mRNA, and induce cell cycle arrest and apoptosis in MCF-7 cell...
T73957 PROTAC Bcl-xL degrader-1
PROTAC Bcl-xL degrader-1 is a PROTAC that comprises a Bcl-xL ( Bcl-2 family member) ligand binding group, a linker and an IAP E3 ligases binding group. PROTAC Bcl-xL degrader-1 is a potent Bcl-xL degrader, and shows toxi...
T74137 PROTAC Bcl-xL ligand-1
PROTAC Bcl-xL ligand-1 is a ligand for Bcl-xL that can be used in the synthesis of PROTACs [1] .
T62941 Bcl-2/Mcl-1-IN-3
Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.
T82902 Beclin1-Bcl-2 interaction inhibitor 1
Beclin1-Bcl-2 Interaction Inhibitor 1 effectively disrupts the binding of Beclin 1 to Bcl-2, and is utilized in cancer and neurodegeneration research [1].
T12824L S55746 BLC201 BCL
S55746 (BLC201) is an effective and selective BCL-2 inhibitor (Ki: 1.3 nM and a Kd of 3.9 nM).
T33467 MOMIPP PI3K
MOMIPP is a PIKfyve inhibitor and a macropinocytosis inducer. MOMIPP readily penetrates the blood-brain barrier and is moderately effective in suppressing progression of intracerebral glioblastoma xenografts[1][2].
T62249 Bcl-2/Mcl-1-IN-1
Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.
T62443 Bcl-2/Mcl-1-IN-2
Bcl-2/Mcl-1-IN-2 is a Bcl-2 (Ki: 4.70 μM) and Mcl-1 (Ki: 0.88 μM) inhibitor.Bcl-2/Mcl-1-IN-2 can be used in cancer research.
T17018 TCPOBOP BCL
TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly. TCPOBOP decreases Fas-induced murine liver injury by altering Bcl-2 proteins.
T10487 BCL6-IN-3 BCL , Others , DNA
BCL6-IN-3 is a potent BCL6 inhibitor with GI50 of 70 nM in SU-DHL4 cells. BCL6-in-3 regulates cell activation, differentiation, DNA damage and apoptosis, and has antitumor activity.
T18363 Monoethyl pimelate Others , PROTAC Linker
Monoethyl pimelate is a <b >PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S,R,S)-AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader[1].
T2099 ABT-737 Mitophagy , BCL , Autophagy
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w (EC50s: 78.7/30.3/197.8 nM).
T11944 Maritoclax Marinopyrrole A BCL
Maritoclax (Marinopyrrole A) (Marinopyrrole A) is a novel and specific Mcl-1 inhibitor, shows >8 fold selectivity than BCL-xl (IC50 > 80 μM),with an IC50 value of 10.1 μM.
T14376 AZD4320 BCL
AZD4320 is an inhibitor of BH3-mimicking dual BCL2/BCLxL. For KPUM-MS3, KPUM-UH1, and STR-428 cells, the IC50s values are 26 nM, 17 nM, and 170 nM , respectively.
T5346 S63845 BCL
S63845 is a selective MCL-1 inhibitor(Kd: 0.19 nM)
T14071 A-385358 BCL
A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.
T6650 Sabutoclax BI-97C1 BCL
Sabutoclax (BI-97C1)(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.
T1980 HA14-1 BCL
HA14-1, a Bcl-2/Bcl-XL antagonist, is a non-peptidic ligand of a Bcl-2 surface pocket (IC50: ~9 μM).
T14561 BI-3812 BCL
BI-3812 is an inhibitor of BCL6. Which inhibiting the BTB domain of BCL6 (IC50: 3 nM). BI-3812 also has antitumor activity.
T6749 A-1331852 BCL
A-1331852 is a potent and selectiveBCL-XL inhibitor and may be useful in the treatment of cancer, immune and autoimmune diseases.
T5108 ML311 BCL
ML311 is a selective inhibitor of the Mcl-1/Bim interaction.
T5408 BI-3802 BCL
BI-3802 is a highly potent BCL6 degrader and inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 value of ≤3 nM. BI-3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. ...
T2453 BAM7 BCL
BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).
T2632 A-1210477 Apoptosis , BCL
A-1210477 is an effective and specific MCL-1 and Bcl-2 inhibitor (Ki/IC50: 0.454/26.2 nM).
T6281 TW-37 TW 37 BCL
TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).
T4089 FX1 Apoptosis , BCL
FX1 is an effective and selective BCL6 inhibitor (IC50: 35 μM).

Compounds

Bcl-xL antagonist 2
T38622
Synonym:
Target: BCL
Bcl-B inhibitor 1
T77571
Synonym:
Target: Apoptosis, BCL
Lisaftoclax
T10483
Synonym: Bcl-2/Bcl-xl inhibitor 1,APG-2575
Target: BCL
Bcl-2-IN-2
T39961
Synonym:
Target:
MCL-1/BCL-2-IN-2
T11969
Synonym:
Target: Others
MCL-1/BCL-2-IN-3
T11970
Synonym:
Target: Others
MCL-1/BCL-2-IN-4
T11971
Synonym:
Target: Others
MCL-1/BCL-2-IN-1
T11968
Synonym:
Target: BCL
Bcl-2-IN-11
T79171
Synonym:
Target:
Bcl-2-IN-4
T74297
Synonym:
Target:
Bcl-2-IN-14
T82912
Synonym:
Target:
Bcl-2-IN-6
T63676
Synonym:
Target:
Bcl-2-IN-16
T82910
Synonym:
Target:
Bcl-2-IN-8
T64053
Synonym:
Target:
TAT-BH4 (Bcl-xL)
T80221
Synonym:
Target: Apoptosis
PROTAC Bcl-xL degrader-2
T74138
Synonym:
Target:
PROTAC Bcl-xL degrader-3
T73999
Synonym:
Target:
TAT-BH4 (Bcl-xL) (TFA)
T80222
Synonym:
Target: Apoptosis
Bcl-2-IN-5
T74298
Synonym:
Target:
Bcl-2-IN-9
T63757
Synonym:
Target:
Bcl-2-IN-12
T82914
Synonym:
Target:
Bcl-2-IN-13
T82913
Synonym:
Target:
Bcl-2-IN-15
T82911
Synonym:
Target:
Bcl-2-IN-7
T63521
Synonym:
Target:
PROTAC Bcl-xL degrader-1
T73957
Synonym:
Target:
PROTAC Bcl-xL ligand-1
T74137
Synonym:
Target:
Bcl-2/Mcl-1-IN-3
T62941
Synonym:
Target:
Beclin1-Bcl-2 interaction inhibitor 1
T82902
Synonym:
Target:
S55746
T12824L
Synonym: BLC201
Target: BCL
MOMIPP
T33467
Synonym:
Target: PI3K
Bcl-2/Mcl-1-IN-1
T62249
Synonym:
Target:
Bcl-2/Mcl-1-IN-2
T62443
Synonym:
Target:
TCPOBOP
T17018
Synonym:
Target: BCL
BCL6-IN-3
T10487
Synonym:
Target: BCL, Others, DNA
Monoethyl pimelate
T18363
Synonym:
Target: Others, PROTAC Linker
ABT-737
T2099
Synonym:
Target: Mitophagy, BCL, Autophagy
Maritoclax
T11944
Synonym: Marinopyrrole A
Target: BCL
AZD4320
T14376
Synonym:
Target: BCL
S63845
T5346
Synonym:
Target: BCL
A-385358
T14071
Synonym:
Target: BCL
Sabutoclax
T6650
Synonym: BI-97C1
Target: BCL
HA14-1
T1980
Synonym:
Target: BCL
BI-3812
T14561
Synonym:
Target: BCL
A-1331852
T6749
Synonym:
Target: BCL
ML311
T5108
Synonym:
Target: BCL
BI-3802
T5408
Synonym:
Target: BCL
BAM7
T2453
Synonym:
Target: BCL
A-1210477
T2632
Synonym:
Target: Apoptosis, BCL
TW-37
T6281
Synonym: TW 37
Target: BCL
FX1
T4089
Synonym:
Target: Apoptosis, BCL
1 2 3 4 5
Cat No. Product Name Synonyms Targets
T3824 Jaceosidin Apoptosis , BCL , COX , UGT
Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...
T8213 Isolinderalactone NOS , STAT
Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
TN1406 Dihydrokaempferol Aromadendrin Apoptosis , BCL
Dihydrokaempferol (Aromadendrin) is a natural product. It induces apoptosis and inhibits Bcl-2 and Bcl-xL expression, possesses anti-inflammatory, antioxidant, and anti-diabetic properties, it exhibits anti-inflammatory ...
TN3967 Epieriocalyxin A ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.
T6518 Gossypol Pogosin,BL 193,NSC 56817 BCL , Dehydrogenase
Gossypol (BL 193) Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
T6S1653 Albiflorin Alibiflorin Reactive Oxygen Species
1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced ...
T6S0052 Chelerythrine Toddalin,Broussonpapyrine,Cheleritrine Apoptosis , BCL , PKC , Autophagy
1. Chelerythrine (Broussonpapyrine) may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiprolifera...
T3419 Chelerythrine chloride Apoptosis , BCL , PKC , Autophagy
Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to ATP.
T2S0500 Ilexsaponin A Ilexsaponin A1 Others
1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.
T5S2358 Dehydrocorydaline Dehydrocorydalin,13-Methylpalmatine BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...
T7979 2-Hydroxychalcone 2-(2-Hydroxybenzal)Acetophenone Apoptosis , BCL , Others , NF-κB
2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated.It can inhibit invasion of triple negative breast cancer cells.
T2S2362 Dehydrocorydaline nitrate BCL , Others , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a...
T10990 Dehydrocorydaline chloride 13-Methylpalmatine chloride BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.
T6185 Gambogic Acid Beta-Guttiferrin,Guttatic Acid,Guttic Acid BCL , Autophagy
Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases. Gambogic Acid competitively suppresses Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1. The IC50s of Gambogic Acid for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 ...
T3322 Trans-Chalcone Chalcone,Cinnamophenone,Chalkone Apoptosis , Others , Antifungal , Fatty Acid Synthase
trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.
T5679 (E)-Ferulic acid trans-Ferulic acid,(E)-Coniferic acid BCL , Ferroptosis , Wnt/beta-catenin , Endogenous Metabolite
(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pr...
T2764 (S)-10-Hydroxycamptothecin 10-Hydroxycamptothecin,10-HCPT Apoptosis , Topoisomerase
(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
T2730 Gossypol (acetic acid) (±)-Gossypol-acetic acid,Pogosin,AT101,Gossypol acetic acid BCL
Gossypol acetic acid (AT101), a polyphenolic compound isolated from cottonseeds, binds with Bcl-2, Bcl-xL, Mcl-1, and does not inhibit BIR3 domain and BID.
T2163 Dihydrocapsaicin CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide Others , TRP/TRPV Channel
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...
T2851 Daphnetin 7,8-Dihydroxycoumarin,Daphnetol EGFR , PKA , PKC , Parasite , Autophagy
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...
T4085 Paris saponin VII Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
T7060 Amantadine 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine Others
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.
T6S1917 Schisandrol B Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B P450 , Reactive Oxygen Species , Autophagy
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...
T3344 Ciwujianoside B yemuoside YM,acanthopanax senticosides B,Ciwujianoside-B BCL , Others
Ciwujianoside B (acanthopanax senticosides B) is the main component of Acanthopanax, can relieve fatigue, enhance memory, and improve human cognition.
T1034 Docetaxel NSC 628503,RP-56976 Apoptosis , Microtubule Associated , Endogenous Metabolite
Docetaxel (RP-56976) is a semi-synthetic analog of paclitaxel, a microtubule depolymerization inhibitor (IC50=0.2 μM). Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression and exhibits apoptosis-inducing,...
T3857 Magnolin (+)-Magnolin ERK
Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.
T6S1529 Cynarin Cyclohexanecarboxyli​c acid, 1,​3-​bis[[3-​(3,​4-​dihydroxyphenyl)​-​1-​oxo-​2-​propen-​1-​yl]​oxy]​-​4,​5-​dihydroxy-​, (1R,​3R,​4S,​5R)​-,Cynarine,1,5-Dicaffeoylquinic acid Antioxidant , Antiviral , Influenza Virus , Reactive Oxygen Species
Cynarin (1,5-Dicaffeoylquinic acid) has neuroprotective, and antioxidant effects, it can inhibition of GSK3β as well as the modulation of Bcl-2/Bax.
T3867 Alpinetin (-)-alpinetin BCL , PPAR
Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to the chemotherapeutic agent CDDP. Alpinetin has strong anti-he...
T7027 EURYCOMANONE Pasakbumin A Others
Eurycomanone (Pasakbumin A) is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibits A549 lung cancer cell p...
T5S2083 Puerarin 6''-O-Xyloside Apoptosis , Caspase
Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 an...
T2795 Amygdalin Laetrile Others
Amygdalin (Laetrile) has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from intervertebral discs of rats induce...
T6S1418 Praeruptorin C Antioxidant , Calcium Channel
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ...
TN2103 PROCYANIDIN C1 Apoptosis
Procyanidin C1 is a natural product, with anti-inflammatory effects, and induces apoptosis.
TN2254 Taccalonolide A Apoptosis , Microtubule Associated
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these ...
T2860 Vanillyl Alcohol 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol Apoptosis , Others
Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant, neuroprotective, and anti-nociceptive activities. Vanillyl alcohol can effectively inhibit ...
T2823 Crocin Gardenia Yellow,Alpha-Crocin Others
Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne...
T3895 Polyphyllin I Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...
T3864 Erianin BCL , Antibacterial
Erianin is a nature product extracted from Dendrobium chrysotoxum, has notable antitumour activity , can cause extensive tumour necrosis, growth delay. Erianin has antiangiogenic action by inhibiting endothelial metaboli...
T6S0653 Linarin Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine TNF , AChE
1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediat...
T3S2344 β,β-Dimethylacrylshikonin Dimethylacrylshikonin,β, β-Dimethylacrylshikonin ERK , HIF/HIF Prolyl-Hydroxylase
1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...
T3923 Calycosin Cyclosin,3'-Hydroxyformononetin Apoptosis , Tyrosinase
Calycosin (Cyclosin) acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Calycosin suppresses breast cancer c...
T2966 Beta-Sitosterol Cupreol,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,22,23-Dihydrostigmasterol,Betaprost Apoptosis , Lipase , Endogenous Metabolite
Beta-Sitosterol (SKF 14463) has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Beta-Sitosterol (SKF 14463) , a main dietary phytosterol foun...
T6S0735 Flavokawain B Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone Apoptosis , Others
1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, in...
T0186 Docetaxel trihydrate RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate Apoptosis , BCL , Microtubule Associated
Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the therapy of many solid tumor i...
T3729 Ethyl gallate Nipagallin A,Phyllemblin,gallic acid ethyl ester MMP , NF-κB , Akt , Antibacterial
Ethyl gallate (gallic acid ethyl ester) obviously decreases cell proliferation in MDA-MB-231 and MCF-7 cells in a dose- and time-dependent manner, exhibits cytotoxicity in a dose-dependent manner. Ethyl gallate can inhib...
T2698 Asperosaponin VI Akebia saponin D,Asperosaponin Ⅵ Apoptosis , Others , Caspase
Asperosaponin VI (Akebia saponin D) , the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.
T2S0410 Euphorbia factor L1 Euphorbiasteroid Apoptosis , P-gp
1. Euphorbia factor L1 (Euphorbiasteroid) can enhance the ATP hydrolysis activity of ABCB1 stimulated by verapamil. 2. Euphorbia factor L1 (Euphorbiasteroid) inhibits the efflux of ABCB1 in KBv200 and MCF-7/adr cells, do...
T5S0661 Koumine Others
1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic effect in rodent behavioral models of infla...
T5526 Glycoborinine BCL , PARP , ROS , Caspase
Glycoborinine is a potential molecule against cancer cells, it can induce HepG2 apoptosis through the mitochondrial-dependent pathway. Glycoborinine has photo-activated antimicrobial activity, it shows moderate inhibitio...
T81229 Safflor yellow B
Safflor Yellow B mitigates angiotensin II-induced injury in human umbilical vein cells by modulating Bcl-2/p22(phox) expression and demonstrates neuroprotective effects [1].
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Natural Products

Jaceosidin
T3824
Synonym:
Target: Apoptosis, BCL, COX, UGT
Isolinderalactone
T8213
Synonym:
Target: NOS, STAT
Dihydrokaempferol
TN1406
Synonym: Aromadendrin
Target: Apoptosis, BCL
Epieriocalyxin A
TN3967
Synonym:
Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK
Gossypol
T6518
Synonym: Pogosin,BL 193,NSC 56817
Target: BCL, Dehydrogenase
Albiflorin
T6S1653
Synonym: Alibiflorin
Target: Reactive Oxygen Species
Chelerythrine
T6S0052
Synonym: Toddalin,Broussonpapyrine,Cheleritrine
Target: Apoptosis, BCL, PKC, Autophagy
Chelerythrine chloride
T3419
Synonym:
Target: Apoptosis, BCL, PKC, Autophagy
Ilexsaponin A
T2S0500
Synonym: Ilexsaponin A1
Target: Others
Dehydrocorydaline
T5S2358
Synonym: Dehydrocorydalin,13-Methylpalmatine
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
2-Hydroxychalcone
T7979
Synonym: 2-(2-Hydroxybenzal)Acetophenone
Target: Apoptosis, BCL, Others, NF-κB
Dehydrocorydaline nitrate
T2S2362
Synonym:
Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Dehydrocorydaline chloride
T10990
Synonym: 13-Methylpalmatine chloride
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Gambogic Acid
T6185
Synonym: Beta-Guttiferrin,Guttatic Acid,Guttic Acid
Target: BCL, Autophagy
trans-Chalcone
T3322
Synonym: Chalcone,Cinnamophenone,Chalkone
Target: Apoptosis, Others, Antifungal, Fatty Acid Synthase
(E)-Ferulic acid
T5679
Synonym: trans-Ferulic acid,(E)-Coniferic acid
Target: BCL, Ferroptosis, Wnt/beta-catenin, Endogenous Metabolite
(S)-10-Hydroxycamptothecin
T2764
Synonym: 10-Hydroxycamptothecin,10-HCPT
Target: Apoptosis, Topoisomerase
Gossypol (acetic acid)
T2730
Synonym: (±)-Gossypol-acetic acid,Pogosin,AT101,Gossypol acetic acid
Target: BCL
Dihydrocapsaicin
T2163
Synonym: CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide
Target: Others, TRP/TRPV Channel
Daphnetin
T2851
Synonym: 7,8-Dihydroxycoumarin,Daphnetol
Target: EGFR, PKA, PKC, Parasite, Autophagy
Paris saponin VII
T4085
Synonym: Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII
Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy
Amantadine
T7060
Synonym: 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine
Target: Others
Schisandrol B
T6S1917
Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B
Target: P450, Reactive Oxygen Species, Autophagy
Ciwujianoside B
T3344
Synonym: yemuoside YM,acanthopanax senticosides B,Ciwujianoside-B
Target: BCL, Others
Docetaxel
T1034
Synonym: NSC 628503,RP-56976
Target: Apoptosis, Microtubule Associated, Endogenous Metabolite
magnolin
T3857
Synonym: (+)-Magnolin
Target: ERK
Cynarin
T6S1529
Synonym: Cyclohexanecarboxyli​c acid, 1,​3-​bis[[3-​(3,​4-​dihydroxyphenyl)​-​1-​oxo-​2-​propen-​1-​yl]​oxy]​-​4,​5-​dihydroxy-​, (1R,​3R,​4S,​5R)​-,Cynarine,1,5-Dicaffeoylquinic acid
Target: Antioxidant, Antiviral, Influenza Virus, Reactive Oxygen Species
Alpinetin
T3867
Synonym: (-)-alpinetin
Target: BCL, PPAR
EURYCOMANONE
T7027
Synonym: Pasakbumin A
Target: Others
Puerarin 6''-O-Xyloside
T5S2083
Synonym:
Target: Apoptosis, Caspase
Amygdalin
T2795
Synonym: Laetrile
Target: Others
Praeruptorin C
T6S1418
Synonym:
Target: Antioxidant, Calcium Channel
PROCYANIDIN C1
TN2103
Synonym:
Target: Apoptosis
Taccalonolide A
TN2254
Synonym:
Target: Apoptosis, Microtubule Associated
Vanillyl Alcohol
T2860
Synonym: 4-Hydroxy-3-methoxybenzenemethanol,3-Methoxy-4-hydroxybenzyl alcohol,4-Hydroxy-3-methoxybenzyl alcohol,Vanillin alcohol,Vanillic alcohol
Target: Apoptosis, Others
Crocin
T2823
Synonym: Gardenia Yellow,Alpha-Crocin
Target: Others
Polyphyllin I
T3895
Synonym:
Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy
Erianin
T3864
Synonym:
Target: BCL, Antibacterial
Linarin
T6S0653
Synonym: Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine
Target: TNF, AChE
β,β-Dimethylacrylshikonin
T3S2344
Synonym: Dimethylacrylshikonin,β, β-Dimethylacrylshikonin
Target: ERK, HIF/HIF Prolyl-Hydroxylase
Calycosin
T3923
Synonym: Cyclosin,3'-Hydroxyformononetin
Target: Apoptosis, Tyrosinase
Beta-Sitosterol
T2966
Synonym: Cupreol,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,22,23-Dihydrostigmasterol,Betaprost
Target: Apoptosis, Lipase, Endogenous Metabolite
Flavokawain B
T6S0735
Synonym: Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone
Target: Apoptosis, Others
Docetaxel trihydrate
T0186
Synonym: RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate
Target: Apoptosis, BCL, Microtubule Associated
Ethyl gallate
T3729
Synonym: Nipagallin A,Phyllemblin,gallic acid ethyl ester
Target: MMP, NF-κB, Akt, Antibacterial
Asperosaponin VI
T2698
Synonym: Akebia saponin D,Asperosaponin Ⅵ
Target: Apoptosis, Others, Caspase
Euphorbia factor L1
T2S0410
Synonym: Euphorbiasteroid
Target: Apoptosis, P-gp
Koumine
T5S0661
Synonym:
Target: Others
Glycoborinine
T5526
Synonym:
Target: BCL, PARP, ROS, Caspase
Safflor yellow B
T81229
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02431 BCL-XL Protein, Human, Recombinant (His) Human E. coli
B-cell lymphoma-extra large (Bcl-xl) is a transmembrane molecule in the mitochondria. Bcl-xL (BCL2L1), belongs to the Bcl-2 family. Members of the bcl-2 family encode proteins that function either to promote or to inhibi...
TMPY-02564 BCL-XL Protein, Mouse, Recombinant (aa 1-212, His) Mouse E. coli
B-cell lymphoma-extra large (Bcl-xl) is a transmembrane molecule in the mitochondria. Bcl-xL (BCL2L1), belongs to the Bcl-2 family. Members of the bcl-2 family encode proteins that function either to promote or to inhibi...
TMPY-02004 BCL-W Protein, Human, Recombinant (His) Human E. coli
Beta1,4-Galactosyltransferase-I (B4GALT1), one of seven beta1,4-galactosyltransferases, is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. They have an N-terminal hydrophobic ...
TMPY-02700 BCL2 Protein, Human, Recombinant (His) Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPJ-00584 Bc1-w Protein, Human, Recombinant (His) Human E. coli
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing thre...
TMPJ-00717 BAG2 Protein, Human, Recombinant (His) Human E. coli
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is...
TMPH-03509 Simian immunodeficiency virus (SIV) (isolate PBj14/BCL-3) Vpx Protein (His & SUMO) SIV E. coli
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by...
TMPY-02430 BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx) Human E. coli
The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexe...
TMPY-04936 BCL2A1 Protein, Human, Recombinant (His) Human E. coli
B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in...
TMPY-03748 BCL2L12 Protein, Human, Recombinant (GST) Human E. coli
BCL2-like 12 (BCL2L12 ) is a new member of the apoptosis-related BCL2 gene family, members of which are implicated in various malignancies. The mRNA expression of BCL2L12 may constitute a novel biomarker for the predicti...
TMPH-01001 BCL10 Protein, Human, Recombinant (His & SUMO) Human E. coli
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essenti...
TMPH-00999 BCL6 Protein, Human, Recombinant (His) Human E. coli
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor pro...
TMPH-03245 BCL2 Protein, Rat, Recombinant (His) Rat in vitro E. coli expression system
A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertio...
TMPH-01000 BCL6 Protein, Human, Recombinant Human E. coli
Probably involved in neuronal development.
TMPH-02520 BCL2 Protein, Mouse, Recombinant (His) Mouse E. coli
Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B. Functions also as a transcriptional coactivator, stimulating transcription mediated by the transc...
TMPY-06842 BMP-4 Protein, Human, Recombinant (E399D) Human E. coli
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-04052 IL-17RB Protein, Human, Recombinant (His) Human HEK293
IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGF...
TMPY-02603 STAT6 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6...
TMPY-04632 IL-15 Protein, Human, Recombinant Human E. coli
The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common h...
TMPJ-00038 IL-7 Protein, Mouse, Recombinant (His) Mouse Human Cells
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 a...
TMPY-03974 Bim Protein, Human, Recombinant (His) Human E. coli
BCL2L11, also known as Bim, belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. ...
TMPK-00636 BID Protein, Mouse, Recombinant (His) Mouse E. coli
Bid, BH3-interacting domain death agonist, was initially cloned based in its ability to interact with both Bcl-2 and Bax. Bid contains only the BH3 domain, which is required for its interaction with the Bcl-2 family prot...
TMPH-00049 Pectate lyase 5 Protein, Ambrosia artemisiifolia, Recombinant (His) Ambrosia artemisiifolia Yeast
apoptosis-inducing factor(AIF) was expressed in luminal alveolar cells and in concert with a change in bax protein to bcl-2 protein ratio might contribute to signalling of a change in the dynamic balance of the cell popu...
TMPH-00495 Lutropin subunit beta Protein, Canine, Recombinant (His) Canine E. coli
Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic pro...
TMPY-04768 PRPS2 Protein, Human, Recombinant (His) Human E. coli
PRPS2, a subset of PRS, is reported to be a potential protein associated with Sertoli-cell only syndrome. PRPS2 expression correlates with Sertoli-cell only syndrome and inhibits the apoptosis of TM4 Sertoli cells via th...
TMPY-02065 BID Protein, Mouse, Recombinant (His & GST) Mouse E. coli
The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro...
TMPY-02027 BID Protein, Human, Recombinant Human E. coli
The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro...
TMPY-02001 RTN4 Protein, Human, Recombinant (GST) Human E. coli
Reticulon-4, also known as Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5 and RTN4, is a multi-pass membrane protein that...
TMPY-00431 BMP-4 Protein, Mouse, Recombinant (rFc) Mouse HEK293
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPJ-01066 CYCS Protein, Human, Recombinant (His) Human E. coli
Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as...
TMPY-00352 IL-17RB Protein, Rhesus, Recombinant (His) Rhesus HEK293
IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGF...
TMPY-03850 IL-17RB Protein, Human, Recombinant (hFc) Human HEK293
IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGF...
TMPY-03471 IL-17RB Protein, Mouse, Recombinant (His) Mouse HEK293
IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGF...
TMPY-04162 IL-17RB Protein, Mouse, Recombinant (hFc) Mouse HEK293
IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGF...
TMPY-04706 IL-17RB Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGF...
TMPJ-00455 SLAMF5 Protein, Mouse, Recombinant (His) Mouse Human Cells
CD84, also called SLAMF5, is a member of the CD2 subgroup of the immunoglobulin receptor superfamily. Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based ...
TMPY-04049 IL-15 Protein, Human, Recombinant (His) Human E. coli
The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common h...
TMPJ-00681 EDIL3 Protein, Human, Recombinant (His) Human Human Cells
EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 (EDIL3) is a 52 kDa extracellular matrix protein that is expressed by endothelial tissues during embryonic vascular development. EDIL3 becomes quiescent at...
TMPY-01824 Caspase-14 Protein, Human, Recombinant (His) Human E. coli
Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses...
TMPY-04417 DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST) Human Baculovirus-Insect Cells
Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK...
TMPY-03795 EIF5A2 Protein, Human, Recombinant (His) Human E. coli
Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted i...
TMPY-04084 ANGPTL1 Protein, Canine, Recombinant (hFc) Canine HEK293
Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an im...
TMPH-02315 XRCC5 Protein, Human, Recombinant (His & Myc) Human E. coli
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negativel...
TMPH-01140 Human coronavirus 229E Spike glycoprotein (His & Myc) HCoV-229E E. coli
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondri...
BCL-XL Protein, Human, Recombinant (His)
TMPY-02431
Species: Human
Expression System: E. coli
BCL-XL Protein, Mouse, Recombinant (aa 1-212, His)
TMPY-02564
Species: Mouse
Expression System: E. coli
BCL-W Protein, Human, Recombinant (His)
TMPY-02004
Species: Human
Expression System: E. coli
BCL2 Protein, Human, Recombinant (His)
TMPY-02700
Species: Human
Expression System: E. coli
Bc1-w Protein, Human, Recombinant (His)
TMPJ-00584
Species: Human
Expression System: E. coli
BAG2 Protein, Human, Recombinant (His)
TMPJ-00717
Species: Human
Expression System: E. coli
Simian immunodeficiency virus (SIV) (isolate PBj14/BCL-3) Vpx Protein (His & SUMO)
TMPH-03509
Species: SIV
Expression System: E. coli
BCL6 Protein, Human, Recombinant (aa 1-150, His & Trx)
TMPY-02430
Species: Human
Expression System: E. coli
BCL2A1 Protein, Human, Recombinant (His)
TMPY-04936
Species: Human
Expression System: E. coli
BCL2L12 Protein, Human, Recombinant (GST)
TMPY-03748
Species: Human
Expression System: E. coli
BCL10 Protein, Human, Recombinant (His & SUMO)
TMPH-01001
Species: Human
Expression System: E. coli
BCL6 Protein, Human, Recombinant (His)
TMPH-00999
Species: Human
Expression System: E. coli
BCL2 Protein, Rat, Recombinant (His)
TMPH-03245
Species: Rat
Expression System: in vitro E. coli expression system
BCL6 Protein, Human, Recombinant
TMPH-01000
Species: Human
Expression System: E. coli
BCL2 Protein, Mouse, Recombinant (His)
TMPH-02520
Species: Mouse
Expression System: E. coli
BMP-4 Protein, Human, Recombinant (E399D)
TMPY-06842
Species: Human
Expression System: E. coli
IL-17RB Protein, Human, Recombinant (His)
TMPY-04052
Species: Human
Expression System: HEK293
STAT6 Protein, Human, Recombinant (His)
TMPY-02603
Species: Human
Expression System: Baculovirus-Insect Cells
IL-15 Protein, Human, Recombinant
TMPY-04632
Species: Human
Expression System: E. coli
IL-7 Protein, Mouse, Recombinant (His)
TMPJ-00038
Species: Mouse
Expression System: Human Cells
Bim Protein, Human, Recombinant (His)
TMPY-03974
Species: Human
Expression System: E. coli
BID Protein, Mouse, Recombinant (His)
TMPK-00636
Species: Mouse
Expression System: E. coli
Pectate lyase 5 Protein, Ambrosia artemisiifolia, Recombinant (His)
TMPH-00049
Species: Ambrosia artemisiifolia
Expression System: Yeast
Lutropin subunit beta Protein, Canine, Recombinant (His)
TMPH-00495
Species: Canine
Expression System: E. coli
PRPS2 Protein, Human, Recombinant (His)
TMPY-04768
Species: Human
Expression System: E. coli
BID Protein, Mouse, Recombinant (His & GST)
TMPY-02065
Species: Mouse
Expression System: E. coli
BID Protein, Human, Recombinant
TMPY-02027
Species: Human
Expression System: E. coli
RTN4 Protein, Human, Recombinant (GST)
TMPY-02001
Species: Human
Expression System: E. coli
BMP-4 Protein, Mouse, Recombinant (rFc)
TMPY-00431
Species: Mouse
Expression System: HEK293
CYCS Protein, Human, Recombinant (His)
TMPJ-01066
Species: Human
Expression System: E. coli
IL-17RB Protein, Rhesus, Recombinant (His)
TMPY-00352
Species: Rhesus
Expression System: HEK293
IL-17RB Protein, Human, Recombinant (hFc)
TMPY-03850
Species: Human
Expression System: HEK293
IL-17RB Protein, Mouse, Recombinant (His)
TMPY-03471
Species: Mouse
Expression System: HEK293
IL-17RB Protein, Mouse, Recombinant (hFc)
TMPY-04162
Species: Mouse
Expression System: HEK293
IL-17RB Protein, Rhesus, Recombinant (hFc)
TMPY-04706
Species: Rhesus
Expression System: HEK293
SLAMF5 Protein, Mouse, Recombinant (His)
TMPJ-00455
Species: Mouse
Expression System: Human Cells
IL-15 Protein, Human, Recombinant (His)
TMPY-04049
Species: Human
Expression System: E. coli
EDIL3 Protein, Human, Recombinant (His)
TMPJ-00681
Species: Human
Expression System: Human Cells
Caspase-14 Protein, Human, Recombinant (His)
TMPY-01824
Species: Human
Expression System: E. coli
DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)
TMPY-04417
Species: Human
Expression System: Baculovirus-Insect Cells
EIF5A2 Protein, Human, Recombinant (His)
TMPY-03795
Species: Human
Expression System: E. coli
ANGPTL1 Protein, Canine, Recombinant (hFc)
TMPY-04084
Species: Canine
Expression System: HEK293
XRCC5 Protein, Human, Recombinant (His & Myc)
TMPH-02315
Species: Human
Expression System: E. coli
Human coronavirus 229E Spike glycoprotein (His & Myc)
TMPH-01140
Species: HCoV-229E
Expression System: E. coli
Cat No. Product Name
L9000 Apoptosis Compound Library

1796 compounds
A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;
TargetMol