TN1211 |
2-Hydroxy-3-methylanthraquinone
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p38 MAPK
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ERK
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Caspase
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2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulat... |
TMPY-02027 |
BID Protein, Human, Recombinant
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The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains onl... |
T71651 |
GSK1370319A
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GSK1370319A is a potent P2X7 antagonist (IC50 = 3.2 nM). GSK1370319A inhibits ATP-induced increase in IL-1β release and ... |
TP2161 |
Z-WEHD-FMK
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Caspase
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Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on ca... |
T41189 |
AY 254
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AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation ve... |
T39586 |
Cantrixil
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TRX-E-002-1 |
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Cantrixil (TRX-E-002-1) is a second-generation super-benzopyran (SBP) compound, derived from TRX-E-002. It elicits an in... |
TMPY-02065 |
BID Protein, Mouse, Recombinant (His & GST Tag)
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The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains onl... |
T62640 |
FPR2 agonist 2
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FPR2 agonist 2 是一种具有血脑屏障通透性的、有效的 FPR2 激动剂 (EC50: 0.13 nM)。FPR2 agonist 2 对促炎细胞因子的产生和 caspase-3 的活性具有抑制作用,抵消线粒体功能的变化。 |
T69745 |
GDC-2394
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GDC-2394 是一种口服有效、选择性的 NLRP3抑制剂,同时也抑制 IL-1β,IC50为 0.4 μM (human IL-1β) 和 0.1 μM (mouse IL-1β)。GDC-2394 抑制 NLRP3诱导的 caspas... |
TMPY-00817 |
Granzyme B Protein, Human, Recombinant (His Tag), HPLC-verified
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Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine protea... |
TN2175 |
Salvianolic acid F
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丹酚酸F,丹酚酸 F |
Caspase
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The role of our hybrid molecules, an analogue of Salvianolic acid F, in compelling the glioma cells towards apoptosis by... |
T72802 |
Spongionellol A
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Spongionellol A 是一种 MDR1(p-糖蛋白) 抑制剂。Spongionellol A 通过诱导 caspase 依赖性的凋亡 (apoptosis) 而对前列腺癌细胞具有较强的细胞毒活性和选择性。Spongionellol... |
T76787 |
Conatumumab
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Conatumumab (AMG 655) 是一种针对人死亡受体 5 (DR5,TRAILR2) 的单克隆激动剂抗体 (Kd: 长型 DR5 为 1 nM, 短型 DR5 为 0.8 nM)。Conatumumab 通过激活 caspase... |
T38838 |
QS-21
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QS-21,Stimulon |
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QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediat... |
TMPY-04003 |
UNC5B Protein, Rat, Recombinant (hFc Tag)
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The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development... |
TMPY-00507 |
UNC5B Protein, Human, Recombinant (ECD, hFc Tag)
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The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development... |
TMPY-04133 |
UNC5B Protein, Human, Recombinant (ECD, His Tag)
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The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development... |
TN6198 |
Mahanine
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Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial m... |
T73792 |
(S)-(-)-Perillic acid
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(S)-(-)-Perillic acid 是一种萜类植物提取物,具有抗菌和抗癌活性。(S)-(-)-Perillic acid 诱导细胞凋亡和细胞周期阻滞,增加细胞内 Bax,Bcl2,p21和 caspase-3的蛋白水平。(S)-(-... |
TMPY-02922 |
XIAP Protein, Human, Recombinant (BIR3 domain, His Tag)
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E3 ubiquitin-protein ligase XIAP / BIRC4, also known as an inhibitor of apoptosis protein 3, X-linked inhibitor of apopt... |