Search Result

Search Results for "caspase"

Compounds

Cat No.	Product Name
T3701	MCC950	CP-456773	NOD
	MCC950 是NLRP3的选择性抑制剂，能够作用于BMDMs(IC50:7.5 nM) 和 HMDMs(IC50:8.1 nM)。		NOD
TN2191	Scutebarbatine A		Caspase , BCL
	Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apopto...		Caspase , BCL
T60348	N1,N11-Diethylnorspermine
	N1,N11-Diethylnorspermine (DENSPM) 是一种有效的抗癌剂。N1,N11-Diethylnorspermine 是一种精胺类似物,可激活多胺分解代谢。N1,N11-Diethylnorspermine 诱导细胞...
T68536	WP-1034
	WP-1034 is a novel Jak-Stat inhibitor, which is active against AML blasts. WP-1034 effectively inhibited proliferation o...
T21978	P-nitro-Pifithrin-α
	p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor. It suppresses p53-mediated TGF-β1...
T36534	SDZ 224-015
	SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1. SDZ 224-015...
TMPY-02078	HtrA2/Omi Protein, Human, Recombinant (His Tag)
	Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine ...
TN4604	Myricanone		BCL , Caspase , NF-κB , ROS , HSP , STAT
	Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activati...		BCL , Caspase , NF-κB , ROS , HSP , STAT
T76007	RGD peptide (GRGDNP) (TFA)
	RGD peptide (GRGDNP) TFA 是整合素-配体相互作用的抑制剂。RGD peptide (GRGDNP) TFA 竞争性抑制α5β1与细胞外基质 (ECM) 的结合。RGD peptide (GRGDNP) TFA 通过激...
T21547	PAF (C16)
	C16-PAF (PAF (C16)) 是一种磷脂介质，是一种血小板活化因子和 PAF G 蛋白偶联受体 (PAFR) 的配体。C16-PAF 具有抗细胞凋亡作用，并通过激活 PAFR 来抑制 caspase 依赖性死亡。C16-PAF 是...
T61823	Anticancer agent 63
	Anticancer agent 63 (compound 3h) exhibits significant cytotoxic activity against multiple cancer cell lines, including ...
TN2945	3-Hydroxybakuchiol		ATPase , Caspase
	3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line ...		ATPase , Caspase
TMPY-01720	DR4/TRAIL R1 Protein, Human, Recombinant (His Tag)
	Tumor necrosis factor receptor superfamily, member 10a (TRAIL R1), also known as TRAIL receptor 1 (TRAIL R1) or CD261 an...
T61327	BRD4 Inhibitor-15
	BRD4 Inhibitor-15 (compound 13) is a highly potent and specific inhibitor of BRD4, effectively inhibiting it with an IC5...
TMPY-01719	DR4/TRAIL R1 Protein, Human, Recombinant (hFc Tag)
	Tumor necrosis factor receptor superfamily, member 10a (TRAIL R1), also known as TRAIL receptor 1 (TRAIL R1) or CD261 an...
T61433	HDAC1-IN-5
	HDAC1-IN-5, a potent inhibitor of HDAC1 with an IC50 value of 15 nM, also exhibits inhibitory activity towards HDAC6 wit...
T62072	HDAC-IN-47
	HDAC-IN-47 是一种口服具有活力的组蛋白去乙酰化酶 (HDAC) 的抑制剂，对 HDAC1、HDAC2、HDAC3、HDAC6、HDAC8 的 IC50 值分别为 19.75 nM、57.8 nM、40.27 nM、5.63 nM、...
T6085	PF-543	PF 543,Sphingosine Kinase 1 Inhibitor II	Apoptosis , S1P Receptor , Autophagy , LPL Receptor
	PF543是一种选择性可逆和鞘氨醇竞争性 SPHK1抑制剂，可诱导细胞凋亡、坏死和自噬。它对 SPHK1的选择性是 SPHK2 的 100 倍以上。它还抑制全血中 1-磷酸鞘氨醇形成，IC50为 26.7 nM。		Apoptosis , S1P Receptor , Autophagy , LPL Receptor
TMPY-01927	ANP32A Protein, Human, Recombinant (His & GST Tag)
	acidic leucine-rich nuclear phosphoprotein 32 family member A, also known as acidic nuclear phosphoprotein pp32, Leuci...
TMPY-04906	RGMB Protein, Human, Recombinant (His Tag)
	RGMB was knocked down in breast cancer cells by way of an anti-RGMB ribozyme transgene. Knockdown of RGMB resulted in en...