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Search Results for " caspase-3/7 "

Targets

28

Compounds

5

Natural Products

73

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T21871 MMPSI Caspase-3/7 Inhibitor I Apoptosis , Caspase
MMPSI (Caspase-3/7 Inhibitor I) is a novel, non-peptide small molecule caspase 3 and caspase 7 inhibitor that reduces ischemic injury in isolated rabbit heart or cardiomyocytes and inhibits apoptosis of H16c2 cells in a ...
T1724 SCR7 pyrazine SCR7 Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).
T10384 Farudodstat ASLAN003 Apoptosis , Dehydrogenase , DNA/RNA Synthesis
Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML.
T5104 BTSA1 Apoptosis , BCL
BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.
T72316 Caspase-3/7 activator 3
Caspase-3/7 Activator 3 is a potent and tumor-selective compound that effectively activates Caspase-3/7, demonstrating significant anti-proliferative activity and a high capacity to induce apoptosis.
T72315 Caspase-3/7 activator 2
Caspase-3/7 Activator 2 is a potent compound that selectively activates Caspase-3/7, demonstrating tumor specificity, anti-proliferative properties, and a high capacity for inducing apoptosis.
T3340 SCR7 Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).
T6085 PF-543 Sphingosine Kinase 1 Inhibitor II,PF 543 Apoptosis , S1P Receptor , Autophagy , LPL Receptor
PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
T8840 PF-543 hydrochloride PF-543 Apoptosis , S1P Receptor , Autophagy , LPL Receptor
PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
T6005 Z-DEVD-FMK Caspase-3 Inhibitor Caspase
Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7, caspase-8, and caspase-10.
T18909 Ac-DEVD-AMC AC-ASP-MET-GLN-ASP-AMC,AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN Caspase
Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .
T8468 CIL62 Caspase
CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].
T22012 7BIO FLT , DYRK , Aurora Kinase
7-bromoindirubin-3'-oxime (7BIO) is a caspase independent nonapoptotic cell death inducer. 7BIO is an inhibitor of FLT3, DYRK1A, DYRK2, Aurora B and Aurora C kinases.
TQ0146 Ac-DEVD-CHO Apoptosis , Caspase
Ac-DEVD-CHO is a specific Caspase-3 inhibitor (Ki: 230 pM).Ac-DEVD-CHO has an inhibitory effect in SLNT-induced apoptosis.
T21293 MX1013 MX 1013,MX-1013
MX1013, a dipeptide pan-caspase inhibitor, inhibits caspase-1, -3, -6, -7, -8, and -9.
T80076 Ac-ESMD-CHO Casein Kinase
Ac-ESMD-CHO functions as an inhibitor of both caspase-3 and caspase-7, specifically obstructing the proteolytic cleavage of the caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site [1] [2].
T36341 Ac-DNLD-AMC
Ac-DNLD-AMC is a fluorogenic caspase-3 substrate. Upon enzymatic cleavage by caspase-3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-3 activity. AMC displays excitation/...
T83205 Ac-DNLD-CHO Ac-Asp-Asn-Leu-Asp-CHO Caspase
Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is an inhibitor of Caspase-3/7, exhibiting IC50 values of 9.89 nM and 245 nM, and approximate Ki values of 0.68 nM and 55.7 nM, respectively. This compound is utilized in the study of...
T36189 CAY10406
CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7. The non-trifluoromethyl compound exhibits Ki values of 1.2 nM and 6 nM for caspases 3 and 7, respectively...
T73683 AC-VEID-CHO TFA
AC-VEID-CHO (TFA) is a peptide-derived inhibitor targeting Caspases-6, -3, and -7, exhibiting IC50 values of 16.2 nM, 13.6 nM, and 162.1 nM, respectively. This compound demonstrates significant inhibitory potency and is ...
T61823 Anticancer agent 63
Anticancer agent 63 (compound 3h) exhibits significant cytotoxic activity against multiple cancer cell lines, including SW480, HeLa, A549, and MCF-7, with IC 50 values of 4.9, 11.5, 9.4, and 3.4 μM, respectively, after 2...
T63522 Anticancer agent 64
Anticancer agent 64 (compound 5m) demonstrates effective cytotoxic activity against CCRF-CEM cells, exhibiting an IC50 value of 2.4 μM. It effectively induces apoptosis in cancer cells by activating caspase 3 and 7 and c...
T79482 Anticancer agent 137 PI3K
Anticancer agent 137 (8q), a potent PI3k inhibitor, exhibits broad-spectrum anticancer activity by inducing G2/M cell cycle arrest and apoptosis. It increases levels of cleaved PARP, and caspases 3 and 7, making it usefu...
T28275 OUP-186 OUP186
OUP-186 is a high affinity and human/rat species-selective antagonist of histamine H3 receptor. OUP-186 suppressed the proliferation of breast cancer cells. The IC50 values at 48 hours for OUP-186 was approximately 50 μM...
T79713 JMJD3/HDAC-IN-1 HDAC
Compound A5b, also known as JMJD3/HDAC-IN-1, is a dual inhibitor that targets both JMJD3 (Jumonji domain-containing protein demethylase 3) and HADC1 (histone deacetylase, IC50 = 16 nM). It induces hypermethylation of his...
T79714 HDAC3-IN-2 HDAC
HDAC3-IN-2 (compound 4i), a pyrazinyl hydrazide-based HDAC3 inhibitor with an IC50 of 14 nM, effectively targets triple-negative breast cancer cells. Demonstrating cytotoxic activity, HDAC3-IN-2 exhibits an IC50 of 0.55 ...
T74783 HDAC-IN-53 HDAC
HDAC-IN-53 is an orally active, selective inhibitor of HDAC1-3, demonstrating IC50 values of 47 nM, 125 nM, and 450 nM, respectively. It exhibits no inhibitory effects on class II HDACs (HDAC4, 5, 6, 7, 9; IC50 >10 μM). ...
T75010 TD1092
TD1092, a pan-IAP degrader, effectively degrades cIAP1, cIAP2, and XIAP, catalyzing the activation of Caspase 3/7 and fostering apoptosis in cancer cells through IAP degradation. It also obstructs the TNFα-mediated NF-κB...

Compounds

MMPSI
T21871
Synonym: Caspase-3/7 Inhibitor I
Target: Apoptosis, Caspase
SCR7 pyrazine
T1724
Synonym: SCR7
Target: Apoptosis, DNA/RNA Synthesis, CRISPR/Cas9
Farudodstat
T10384
Synonym: ASLAN003
Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis
BTSA1
T5104
Synonym:
Target: Apoptosis, BCL
Caspase-3/7 activator 3
T72316
Synonym:
Target:
Caspase-3/7 activator 2
T72315
Synonym:
Target:
SCR7
T3340
Synonym:
Target: Apoptosis, DNA/RNA Synthesis, CRISPR/Cas9
PF-543
T6085
Synonym: Sphingosine Kinase 1 Inhibitor II,PF 543
Target: Apoptosis, S1P Receptor, Autophagy, LPL Receptor
PF-543 hydrochloride
T8840
Synonym: PF-543
Target: Apoptosis, S1P Receptor, Autophagy, LPL Receptor
Z-DEVD-FMK
T6005
Synonym: Caspase-3 Inhibitor
Target: Caspase
Ac-DEVD-AMC
T18909
Synonym: AC-ASP-MET-GLN-ASP-AMC,AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN
Target: Caspase
CIL62
T8468
Synonym:
Target: Caspase
7BIO
T22012
Synonym:
Target: FLT, DYRK, Aurora Kinase
Ac-DEVD-CHO
TQ0146
Synonym:
Target: Apoptosis, Caspase
MX1013
T21293
Synonym: MX 1013,MX-1013
Target:
Ac-ESMD-CHO
T80076
Synonym:
Target: Casein Kinase
Ac-DNLD-AMC
T36341
Synonym:
Target:
Ac-DNLD-CHO
T83205
Synonym: Ac-Asp-Asn-Leu-Asp-CHO
Target: Caspase
CAY10406
T36189
Synonym:
Target:
AC-VEID-CHO TFA
T73683
Synonym:
Target:
Anticancer agent 63
T61823
Synonym:
Target:
Anticancer agent 64
T63522
Synonym:
Target:
Anticancer agent 137
T79482
Synonym:
Target: PI3K
OUP-186
T28275
Synonym: OUP186
Target:
JMJD3/HDAC-IN-1
T79713
Synonym:
Target: HDAC
HDAC3-IN-2
T79714
Synonym:
Target: HDAC
HDAC-IN-53
T74783
Synonym:
Target: HDAC
TD1092
T75010
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T5S2083 Puerarin 6''-O-Xyloside Apoptosis , Caspase
Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 an...
T5S2358 Dehydrocorydaline Dehydrocorydalin,13-Methylpalmatine BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...
T2S2362 Dehydrocorydaline nitrate BCL , Others , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a...
T3S2344 β,β-Dimethylacrylshikonin Dimethylacrylshikonin,β, β-Dimethylacrylshikonin ERK , HIF/HIF Prolyl-Hydroxylase
1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...
TN4903 Regiolone Caspase
Regiolone demonstrates phytotoxicity. Regiolone also has anti-proliferative and apoptotic activities, it can induce apoptosis in MCF-7 cells through the caspase-3 independent pathway.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02831 Caspase-7 Protein, Human, Recombinant (His) Human E. coli
Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family. Caspases play a role in the signal transduction pathways of apoptosis, necrosis and inflammation. There are tw...
TMPJ-01256 Caspase-10 Protein, Human, Recombinant (His) Human E. coli
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granz...
TMPY-01824 Caspase-14 Protein, Human, Recombinant (His) Human E. coli
Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses...
TMPY-02922 XIAP Protein, Human, Recombinant (His) Human E. coli
E3 ubiquitin-protein ligase XIAP / BIRC4, also known as an inhibitor of apoptosis protein 3, X-linked inhibitor of apoptosis protein, and IAP-like protein, is a protein that belongs to a family of apoptotic suppressor pr...
TMPY-01216 XIAP Protein, Human, Recombinant (Avi) Human E. coli
E3 ubiquitin-protein ligase XIAP / BIRC4, also known as an inhibitor of apoptosis protein 3, X-linked inhibitor of apoptosis protein, and IAP-like protein, is a protein that belongs to a family of apoptotic suppressor pr...
TMPJ-00770 Granzyme B/GZMB Protein, Mouse, Recombinant (His) Mouse Human Cells
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an...
TMPY-06036 FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc) Human HEK293
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-00132 Mesothelin Protein, Human, Recombinant Human HEK293
The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glyc...
TMPY-00357 HNT/NTM Protein, Human, Recombinant (His) Human HEK293
NTM (Neurotrimin) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylph...
TMPY-06986 FGF-8b Protein, Human, Recombinant Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-04683 CD47 Protein, Human, Recombinant Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-01020 Periostin/OSF-2 Protein, Human, Recombinant (His) Human HEK293
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-01897 PRSS3 Protein, Human, Recombinant (His) Human HEK293
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-03763 Neuropilin-2 Protein, Human, Recombinant (hFc) Human HEK293
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-00892 Neuropilin-2 Protein, Human, Recombinant (His) Human HEK293
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-04935 CD47 Protein, Human, Recombinant (aa 1-139, His) Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-00072 GITR/TNFRSF18 Protein, Human, Recombinant (His) Human HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)...
TMPY-04298 CDCP1 Protein, Human, Recombinant (His) Human HEK293
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-00480 NCAM1 Protein, Human, Recombinant (His) Human HEK293
NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobuli...
TMPY-01180 CD86 Protein, Human, Recombinant (His) Human HEK293
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPJ-01099 IL-15RA Protein, Human, Recombinant (hFc)(Human Cells) Human Human Cells
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bi...
TMPK-01371 IGFBP-7 Protein, Human, Recombinant (hFc) Human HEK293
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 ...
TMPK-00828 Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc) Human HEK293
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire...
TMPK-00394 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in num...
TMPK-00395 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differen...
TMPY-06035 FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPK-00392 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in num...
TMPK-00393 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293
Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differen...
TMPK-00447 CD45 Protein, Human, Recombinant (aa 26-577, hFc) Human HEK293
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPY-03883 CD47 Protein, Human, Recombinant (hFc) Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-04273 FGFR2 Protein, Human, Recombinant (aa 1-378, His) Human HEK293
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-03969 SUSD4 Protein, Human, Recombinant (mFc) Human HEK293
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ...
TMPK-00399 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated Human HEK293
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPJ-00899 HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) Human Human Cells
Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belon...
TMPY-01268 SMYD3 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger...
TMPY-05590 NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobuli...
TMPY-04157 RANK/TNFRSF11A Protein, Human, Recombinant (His) Human HEK293
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-01656 VEGF183 Protein, Human, Recombinant Human Baculovirus-Insect Cells
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-05383 NKp30/NCR3 Protein, Human, Recombinant (hFc) Human HEK293
Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and...
TMPY-06411 GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)...
TMPJ-00390 FGFR2IIIb Protein, Human, Recombinant (hFc) Human Human Cells
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-05246 CD86 Protein, Human, Recombinant (His), Biotinylated Human HEK293
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPY-03621 EphB2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5...
TMPY-02691 IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) Human HEK293
IL17RC (Interleukin 17 Receptor C) is a Protein Coding gene. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). IL17RC is widely expressed in the pr...
TMPJ-00391 FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) Human Human Cells
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPJ-00054 PLGF-2 Protein, Human, Recombinant (His) Human Human Cells
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. Alternate splicing results in at least three human mature PlGF f...
TMPY-03435 NCKIPSD Protein, Human, Recombinant (GST) Human E. coli
NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an importa...
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Caspase-7 Protein, Human, Recombinant (His)
TMPY-02831
Species: Human
Expression System: E. coli
Caspase-10 Protein, Human, Recombinant (His)
TMPJ-01256
Species: Human
Expression System: E. coli
Caspase-14 Protein, Human, Recombinant (His)
TMPY-01824
Species: Human
Expression System: E. coli
XIAP Protein, Human, Recombinant (His)
TMPY-02922
Species: Human
Expression System: E. coli
XIAP Protein, Human, Recombinant (Avi)
TMPY-01216
Species: Human
Expression System: E. coli
Granzyme B/GZMB Protein, Mouse, Recombinant (His)
TMPJ-00770
Species: Mouse
Expression System: Human Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
TMPY-06036
Species: Human
Expression System: HEK293
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
TMPY-04142
Species: Human
Expression System: HEK293
Mesothelin Protein, Human, Recombinant
TMPY-00132
Species: Human
Expression System: HEK293
HNT/NTM Protein, Human, Recombinant (His)
TMPY-00357
Species: Human
Expression System: HEK293
FGF-8b Protein, Human, Recombinant
TMPY-06986
Species: Human
Expression System: E. coli
CD45 Protein, Human, Recombinant (aa 26-577, His)
TMPY-05748
Species: Human
Expression System: HEK293
CD47 Protein, Human, Recombinant
TMPY-04683
Species: Human
Expression System: HEK293
Periostin/OSF-2 Protein, Human, Recombinant (His)
TMPY-01020
Species: Human
Expression System: HEK293
PRSS3 Protein, Human, Recombinant (His)
TMPY-01897
Species: Human
Expression System: HEK293
CD47 Protein, Human, Recombinant, Biotinylated
TMPY-05191
Species: Human
Expression System: HEK293
Neuropilin-2 Protein, Human, Recombinant (hFc)
TMPY-03763
Species: Human
Expression System: HEK293
Neuropilin-2 Protein, Human, Recombinant (His)
TMPY-00892
Species: Human
Expression System: HEK293
CD47 Protein, Human, Recombinant (aa 1-139, His)
TMPY-04935
Species: Human
Expression System: HEK293
GITR/TNFRSF18 Protein, Human, Recombinant (His)
TMPY-00072
Species: Human
Expression System: HEK293
CDCP1 Protein, Human, Recombinant (His)
TMPY-04298
Species: Human
Expression System: HEK293
NCAM1 Protein, Human, Recombinant (His)
TMPY-00480
Species: Human
Expression System: HEK293
CD86 Protein, Human, Recombinant (His)
TMPY-01180
Species: Human
Expression System: HEK293
IL-15RA Protein, Human, Recombinant (hFc)(Human Cells)
TMPJ-01099
Species: Human
Expression System: Human Cells
IGFBP-7 Protein, Human, Recombinant (hFc)
TMPK-01371
Species: Human
Expression System: HEK293
Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)
TMPK-00828
Species: Human
Expression System: HEK293
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00394
Species: Human
Expression System: HEK293
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00395
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
TMPY-06035
Species: Human
Expression System: HEK293
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00392
Species: Human
Expression System: HEK293
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00393
Species: Human
Expression System: HEK293
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
TMPK-00447
Species: Human
Expression System: HEK293
CD47 Protein, Human, Recombinant (hFc)
TMPY-03883
Species: Human
Expression System: HEK293
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
TMPY-04273
Species: Human
Expression System: HEK293
SUSD4 Protein, Human, Recombinant (mFc)
TMPY-03969
Species: Human
Expression System: HEK293
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
TMPK-00399
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)
TMPJ-00899
Species: Human
Expression System: Human Cells
SMYD3 Protein, Human, Recombinant (GST)
TMPY-01268
Species: Human
Expression System: Baculovirus-Insect Cells
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05590
Species: Human
Expression System: HEK293
RANK/TNFRSF11A Protein, Human, Recombinant (His)
TMPY-04157
Species: Human
Expression System: HEK293
VEGF183 Protein, Human, Recombinant
TMPY-01656
Species: Human
Expression System: Baculovirus-Insect Cells
NKp30/NCR3 Protein, Human, Recombinant (hFc)
TMPY-05383
Species: Human
Expression System: HEK293
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06411
Species: Human
Expression System: HEK293
FGFR2IIIb Protein, Human, Recombinant (hFc)
TMPJ-00390
Species: Human
Expression System: Human Cells
CD86 Protein, Human, Recombinant (His), Biotinylated
TMPY-05246
Species: Human
Expression System: HEK293
EphB2 Protein, Mouse, Recombinant (hFc)
TMPY-03621
Species: Mouse
Expression System: HEK293
IL-17RC Protein, Human, Recombinant(aa 1-454, hFc)
TMPY-02691
Species: Human
Expression System: HEK293
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
TMPJ-00391
Species: Human
Expression System: Human Cells
PLGF-2 Protein, Human, Recombinant (His)
TMPJ-00054
Species: Human
Expression System: Human Cells
NCKIPSD Protein, Human, Recombinant (GST)
TMPY-03435
Species: Human
Expression System: E. coli
TargetMol