dmt-2'fluoro-da(bz) amidite

Dmt-2'fluoro-da(bz) amidite is a 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotide with high affinity and specificity for RNA targets and serves as an intermediate in the synthesis of 5'-DMT-3'-phosphoramidite, an antisense compound resistant to nuclease.

4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagonist with Ki = 1.0 nM for human CRF-R1.

(Z)-2-fluoro-1,3-bis(4-methoxyphenyl)prop-2-en-1-one is a screening compound and can be used in new drug development related research.

1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a fluoro-modified nucleoside, specifically an Arabino-nucleoside.

2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxylic acid is commonly used to synthesize compounds with anticancer and antitumor properties.

2’-Deoxy-2’-fluoro-β-D-arabinocytidine hydrochloride is a cytosine nucleoside analog with inhibitory effects on DNA methyltransferase , with potential antimetabolic and antitumor activity.

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite, an adenine nucleoside analog, has potential vasodilator and anticancer activities relevant to cancer research.

2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis. The anticancer mechanism of 2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine is dependent on the inhibition of DNA synthesis.

5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine 2',3'-diacetate is an intermediate in the synthesis of capecitabine.

DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.

2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors expressing E. coli PNP. 2'-Fluoro-2'-Deoxyadenosine can be used to synthesize 2'-deoxy-2'-fluoromodified oligonucleotides that can hybridize to RNA.

(S)-Ethyl 2-amino-4-fluoro-4-methylpentanoate sulfate, catalog number T67199 and CAS number 848949-85-9, is a valuable compound for life sciences research.

Nucleoside Derivatives - 2’-Modified nucleosides, 8-Modified purine nucleosides, Halo-nucleosides, Fluoro-modified nucleosides

Nucleoside Derivatives - 6-Modified purine nucleosides; Halo-nucleosides; Fluoro-modified nucleosides

Nucleoside, halo-nucleoside, 2’-O-Methyl nucleoside

N6-Bz-5'-O-DMTr-3'-O-methyladenosine-2'-O-CED-phosphoramidite is a Nucleoside Phosphoramidite.

Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-D-arabinopentofuranoside (catalog number: TNU1339, CAS number: 221552-92-7) is a valuable organic compound for life sciences research.

2'-Deoxy-2'-fluoro-b-D-arabino-6-azauridine is a Nucleoside Derivative - 6-Aza-uridine; Fluoro-modified nucleoside; Arabino nucleoside.

Nucleoside Derivatives –2’-Modified nucleosides; Thio-nucleosides

5'-DMT-3'-TBDMS-Bz-rA is a nucleoside possessing protective and modification effects.

2-Fluoro-4-iodo benzonitrile is a building block.1,2It has been used in the synthesis ofL. infantumtrypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors.12-Fluoro-4-iodo benzonitrile has also been used in the synthesis of transient receptor potential ankyrin 1 (TRPA1) antagonists.2 1.Revuelto, A., Ruiz-Santaquiteria, M., de Lucio, H., et al.Pyrrolopyrimidine vs imidazole-phenyl-thiazole scaffolds in nonpeptidic dimerization inhibitors of Leishmania infantum trypanothione reductaseACS Infect. Dis.5(6)873-891(2019) 2.Vallin, K.S., Sterky, K.J., Nyman, E., et al.N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptorBioorg. Med. Chem. Lett.22(17)5485-5492(2012)

2'-Deoxy-2'-fluoro-5-iodouridine is a nucleoside, specifically a fluoro-modified and halo-nucleoside.

3'-dC(Bz)-2'-phosphoramidite is a Nucleoside Phosphoramidite.

5'-O-DMT-2'-O-TBDMS-Bz-rC, a modified nucleoside, is used in DNA or RNA synthesis.

DMT-2'-OMe-Bz-C is a 2'-O-Methyl nucleoside.

5’-O-TBDMS-Bz-dA is a nucleoside known for its protective and modification effects.

2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a nucleoside phosphoramidite.

Nucleoside Phosphoramidites;Arabino-nucleosides

5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies, stemming from the inhibition of DNA synthesis and the induction of apoptosis, among other mechanisms [1].

2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effective against indolent lymphoid malignancies, primarily by inhibiting DNA synthesis and inducing apoptosis among other mechanisms [1].

5’-DMTr-3’dA(Bz)-methylphosphonamidite, a purine nucleoside analog, exhibits significant antitumor activity against indolent lymphoid malignancies by inhibiting DNA synthesis and inducing apoptosis, among other mechanisms [1].

N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog that inhibits DNA methyltransferases (such as Zebularine).

2'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis, among other mechanisms [1].

DMT-dA(PAc) Phosphoramidite is a diPhosphoramidite suitable for DNA or RNA synthesis applications.

5-Fluoro-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a useful organic compound for research related to life sciences and the catalog number is T64799.

Fluoro-modified nucleoside; 2/6/8-Modified purine nucleoside; Arabino-nucleoside

2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is a fluoro-modified nucleoside, specifically a 5-modified pyrimidine nucleoside and 2'-modified nucleoside.

4-Chloro-5-fluoro-2-methoxypyrimidine is a useful organic compound for research related to life sciences. The catalog number is T66421 and the CAS number is 1801-06-5.

2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)uridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 2'-Modified nucleoside.

2-Acetamido-2,4-dideoxy-4-fluoro-α-D-glucopyranose (compound 13) is a potent inhibitor of hepatic glycosaminoglycan biosynthesis.

5-Fluoro-2-methoxypyrimidin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T65843 and the CAS number is 1993-63-1.

5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside used in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.

(R)-DMT-glycidol-A(Bz) is a Nucleoside Derivative - Acyclic nucleoside.

2-Amino-6-chloropurine -9-beta-D-(2'-deoxy-3',5'-di-O-benzoyl-2'-fluoro)arabinoriboside is a fluoro-modified nucleoside, halo-nucleoside, and arabino-nucleoside.

4-Chloro-7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a Nucleoside - 7-deazapurine nucleoside, fluoronucleoside, halo nucleoside; Arabino-nucleoside.

2'-F-Bz-dC Phosphoramidite is used in the synthesis of oligoribonucleotides.

Nucleoside Derivatives - Fluoro-modified nucleosides, 7-Deaza-purine nucleosides

N4-Benzoyl-2’-deoxy-2’-fluoro-b-D-arabinocytidine is a useful organic compound for research related to life sciences and the catalog number is TNU1174.