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Search Results for " dna��������������� "

1619

Compounds

282

Natural Products

542

Recombinant Proteins

15

Libraries

Cat No. Product Name Synonyms Targets
T80644 DNA polymerase-IN-1 Antiviral , DNA/RNA Synthesis
DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an I...
T31554 DNA-Spermidine DA-51,DA 51,DA51,DNA Spermidine
DNA-spermidine influences the activity of restricted endonuclease from several bacterial species.
T27194 DNA Primase Inhibitor-13
DNA Primase Inhibitor-13 is a novel inhibitor of DNA primase.
T4517 L189 DNA , DNA/RNA Synthesis
L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).
T1904 SGI-1027 DNA Methyltransferase Inhibitor II,SGI1027 Apoptosis , DNA Methyltransferase
SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027(SGI1027) against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively.
T3103 L67 DNA Ligase Inhibitor DNA , DNA/RNA Synthesis
L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
T8873 Bractoppin Others , DNA/RNA Synthesis
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi...
T12019 Methylproamine Others
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.
T2433 NU 7026 NU7026,DNA-PK Inhibitor II,LY293646 Apoptosis , ATM/ATR , DNA-PK , PI3K
NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition against both ATM and ATR.
T0164 Oxaliplatin L-OHP DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autop...
T11469 GSK-3484862 DNA Methyltransferase
GSK-3484862 is a non-covalent Dnmt1 inhibitor. It induces DNA hypomethylation to against cancer.
T15080 DC-05 DNA Methyltransferase , Histone Methyltransferase
DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).
T15789 LTURM34 DNA-PK , PI3K , PI4K
LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM. LTURM34 displays effective antiproliferative activity in a wide range of tumor cell lines. LTURM34 shows 170-fold selectivity for DNA-PK over PI3K .
T4339 YU238259 DNA-PK , Others
YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.
T36757 DMT-dU-CE Phosphoramidite DNA/RNA Synthesis
DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.
T16269 Nanaomycin A DNA Methyltransferase , Dehydrogenase , Parasite
Nanaomycin A, a quinone antibiotics, reactivates silenced tumor suppressor genes in human cancer cells. Nanaomycin A is a selective inhibitor of DNMT3B (IC50 = 500 nM).
T0707L Cyclophosphamide DNA Alkylator/Crosslinker , DNA , MRP
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
T2461 PIK-90 DNA-PK , PI3K
PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) .
T6100 Torin 2 Apoptosis , ATM/ATR , DNA-PK , mTOR , Autophagy
Torin 2(IC50=0.25 nM), a specific and effective mTOR inhibitor, is the 800-fold greater specific activity for mTOR than PI3K and improves pharmacokinetic properties. The EC50 of Torin 2 for ATM/ATR/DNA-PK inhibition is 2...
T8747 Levofloxacin hydrochloride DNA gyrase , Topoisomerase
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inh...
T2495 Lomeguatrib PaTrin-2 DNA Methyltransferase , DNA Alkylation
Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .
T5198 Bobcat339 Bobcat339 hydrochloride DNA Methyltransferase
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.
T8967 SW155246 DNA Methyltransferase
SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1; IC50 of 1.2 μM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.
T8354 Triazavirin Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.
T1767 BMH-21 BMH21 DNA/RNA Synthesis
BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.
T1564 Cisplatin cis-Diaminodichloroplatinum,CDDP DNA Alkylator/Crosslinker , Ferroptosis , DNA/RNA Synthesis , Autophagy
Cisplatin (CDDP) is a DNA cross-linking agent. Cisplatin has antitumor activity and inhibits DNA synthesis by forming DNA adducts in cancer cells. Cisplatin also activates iron death and induces autophagy.
T60034 TH1085 Others
TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).
T21463 Temozolomide Acid TMZA Others
Temozolomide Acid (TMZA) is a metabolite of temozolomide (TMZ). Temozolomide processes anticancer activity in vitro. Temozolomide (TMZ) is an oral alkylating agent used to treat glioblastoma multiforme (GBM) and astrocyt...
T79922 Taq DNA polymerase DNA/RNA Synthesis
Taq DNA polymerase is a thermostable enzyme utilized in polymerase chain reactions (PCR) to amplify DNA sequences [1].
T3986 SF2523 DNA-PK , Epigenetic Reader Domain , PI3K , mTOR
SF2523 is a highly selective and potent inhibitor.
T15793 Lurbinectedin PM01183 Others
Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.
T11120 Duocarmycin TM DNA Alkylation , Antibiotic
Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.
T3541 CC-115 CC 115 DNA-PK , PI3K , mTOR
CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).
T5017 Nimustine Hydrochloride Nidran hydrochloride Apoptosis , Others , DNA Alkylator/Crosslinker , DNA/RNA Synthesis
Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.
T1058 Carboplatin NSC 241240,CBDCA,JM-8 DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
Carboplatin (JM-8) is an organoplatinum compound that possesses antineoplastic activity.
T7718 5-Fluoro-2'-deoxycytidine FdCyd,2'-DEOXY-5-FLUOROCYTIDINE DNA Methyltransferase
5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .
T36756 DMT-dG(ib) Phosphoramidite DNA/RNA Synthesis
DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.
T9573 GSK3685032 DNA Methyltransferase
GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM). The inhibitory effect is time-independent and reversible. GSK3685032 induces loss of DNA methylation and transcriptional activation and inhibits c...
T8648 6-AZATHYMINE Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis , Antibacterial
6-azathymine is a potent inhibitors of D-3-aminoisobutyrate-pyruvate aminotransferase. 6-Azauracil acted as a competitive inhibitor with respect to beta-alanine, and was an uncompetitive inhibitor with respect to pyruvic...
T6801 CeMMEC13 Carboxypeptidase , DNA/RNA Synthesis
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
T9760 IC 86621 DNA-PK
IC 86621 is a selective and reversible ATP-competitive inhibitor of DNA-PK with an IC50 of 120 nM. IC 86621 increases DNA double-strand break(DSB)-induced antitumor activity with an EC50 of 68 µM for DNA-PK mediated cell...
T2169 Zebularine NSC309132,4-Deoxyuridine DNA Methyltransferase , Autophagy
Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor. Acts as a transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates. It also inhibits cytidine deaminase (Ki: 2...
T8380 Bendamustine SDX105 Apoptosis , Others , DNA Alkylator/Crosslinker
Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia
T6557 KU-0060648 KU0060648 DNA-PK , PI3K , mTOR
KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.
T38272 Thiacloprid AChR , Parasite
Thiacloprid is a neonicotinoid insecticide that acts as a selective agonist at insect nicotinic acetylcholine receptors (nAChRs) with IC50values of 2.7 and 860 nM forDrosophilanAChRs and M10 mouse fibroblast cells expres...
T15611 JH-RE-06 DNA/RNA Synthesis
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interact...
T2038 RG108 N-Phthalyl-L-tryptophan DNA Methyltransferase
RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).
T2667 PIK-75 Apoptosis , DNA-PK , PI3K
PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).
T15146 DNA2 inhibitor C5 Others
DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM)...
T1154 Rifaximin DNA/RNA Synthesis , Antibacterial , Antibiotic
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting...

Compounds

DNA polymerase-IN-1
T80644
Synonym:
Target: Antiviral, DNA/RNA Synthesis
DNA-Spermidine
T31554
Synonym: DA-51,DA 51,DA51,DNA Spermidine
Target:
DNA Primase Inhibitor-13
T27194
Synonym:
Target:
L189
T4517
Synonym:
Target: DNA, DNA/RNA Synthesis
SGI-1027
T1904
Synonym: DNA Methyltransferase Inhibitor II,SGI1027
Target: Apoptosis, DNA Methyltransferase
L67
T3103
Synonym: DNA Ligase Inhibitor
Target: DNA, DNA/RNA Synthesis
Bractoppin
T8873
Synonym:
Target: Others, DNA/RNA Synthesis
Methylproamine
T12019
Synonym:
Target: Others
NU 7026
T2433
Synonym: NU7026,DNA-PK Inhibitor II,LY293646
Target: Apoptosis, ATM/ATR, DNA-PK, PI3K
Oxaliplatin
T0164
Synonym: L-OHP
Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis, Autophagy
GSK-3484862
T11469
Synonym:
Target: DNA Methyltransferase
DC-05
T15080
Synonym:
Target: DNA Methyltransferase, Histone Methyltransferase
LTURM34
T15789
Synonym:
Target: DNA-PK, PI3K, PI4K
YU238259
T4339
Synonym:
Target: DNA-PK, Others
DMT-dU-CE Phosphoramidite
T36757
Synonym:
Target: DNA/RNA Synthesis
Nanaomycin A
T16269
Synonym:
Target: DNA Methyltransferase, Dehydrogenase, Parasite
Cyclophosphamide
T0707L
Synonym:
Target: DNA Alkylator/Crosslinker, DNA, MRP
PIK-90
T2461
Synonym:
Target: DNA-PK, PI3K
Torin 2
T6100
Synonym:
Target: Apoptosis, ATM/ATR, DNA-PK, mTOR, Autophagy
Levofloxacin hydrochloride
T8747
Synonym:
Target: DNA gyrase, Topoisomerase
Lomeguatrib
T2495
Synonym: PaTrin-2
Target: DNA Methyltransferase, DNA Alkylation
Bobcat339
T5198
Synonym: Bobcat339 hydrochloride
Target: DNA Methyltransferase
SW155246
T8967
Synonym:
Target: DNA Methyltransferase
Triazavirin
T8354
Synonym:
Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis
BMH-21
T1767
Synonym: BMH21
Target: DNA/RNA Synthesis
Cisplatin
T1564
Synonym: cis-Diaminodichloroplatinum,CDDP
Target: DNA Alkylator/Crosslinker, Ferroptosis, DNA/RNA Synthesis, Autophagy
TH1085
T60034
Synonym:
Target: Others
Temozolomide Acid
T21463
Synonym: TMZA
Target: Others
Taq DNA polymerase
T79922
Synonym:
Target: DNA/RNA Synthesis
SF2523
T3986
Synonym:
Target: DNA-PK, Epigenetic Reader Domain, PI3K, mTOR
Lurbinectedin
T15793
Synonym: PM01183
Target: Others
Duocarmycin TM
T11120
Synonym:
Target: DNA Alkylation, Antibiotic
CC-115
T3541
Synonym: CC 115
Target: DNA-PK, PI3K, mTOR
Nimustine Hydrochloride
T5017
Synonym: Nidran hydrochloride
Target: Apoptosis, Others, DNA Alkylator/Crosslinker, DNA/RNA Synthesis
Carboplatin
T1058
Synonym: NSC 241240,CBDCA,JM-8
Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis, Autophagy
5-Fluoro-2'-deoxycytidine
T7718
Synonym: FdCyd,2'-DEOXY-5-FLUOROCYTIDINE
Target: DNA Methyltransferase
DMT-dG(ib) Phosphoramidite
T36756
Synonym:
Target: DNA/RNA Synthesis
GSK3685032
T9573
Synonym:
Target: DNA Methyltransferase
6-AZATHYMINE
T8648
Synonym:
Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis, Antibacterial
CeMMEC13
T6801
Synonym:
Target: Carboxypeptidase, DNA/RNA Synthesis
IC 86621
T9760
Synonym:
Target: DNA-PK
Zebularine
T2169
Synonym: NSC309132,4-Deoxyuridine
Target: DNA Methyltransferase, Autophagy
Bendamustine
T8380
Synonym: SDX105
Target: Apoptosis, Others, DNA Alkylator/Crosslinker
KU-0060648
T6557
Synonym: KU0060648
Target: DNA-PK, PI3K, mTOR
Thiacloprid
T38272
Synonym:
Target: AChR, Parasite
JH-RE-06
T15611
Synonym:
Target: DNA/RNA Synthesis
RG108
T2038
Synonym: N-Phthalyl-L-tryptophan
Target: DNA Methyltransferase
PIK-75
T2667
Synonym:
Target: Apoptosis, DNA-PK, PI3K
DNA2 inhibitor C5
T15146
Synonym:
Target: Others
Rifaximin
T1154
Synonym:
Target: DNA/RNA Synthesis, Antibacterial, Antibiotic
1 ... 4 5 6 ... 33
Cat No. Product Name Synonyms Targets
T13592 Calf thymus DNA DNA from calf thymus, Thymonucleic acid DNA/RNA Synthesis
Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) is a high-quality double-stranded template DNA extracted from the bovine thymus gland, which can be widely used in the study of DNA binding anticancer agents and ...
T21498 Phleomycin DNA/RNA Synthesis , Antibacterial , Antibiotic
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.
T37101 1-Hydroxyanthraquinone DNA/RNA Synthesis
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
T1068 Dithranol 1,8,9-trihydroxyanthracene,cignoline,Anthralin Others , DNA/RNA Synthesis
Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.
T7520 Deoxycytidine triphosphate Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
T13969 Xanthopterin (hydrate) Others , DNA/RNA Synthesis
Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species.
T6S0139 Neobavaisoflavone Apoptosis , DNA/RNA Synthesis
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...
TN2132 Quinizarin 1,4-Dihydroxyanthraquinone Others , DNA/RNA Synthesis , Antifungal
Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product
T40179 Sodium Camptothecin DNA/RNA Synthesis
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin i...
T12651 Rabdosiin (+)-Rabdosiin Others
Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase.
T0064 Adenine Vitamin B4,6-Aminopurine DNA/RNA Synthesis , Endogenous Metabolite , AChR
Adenine (6-Aminopurine), a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NAD and FAD, and protein synthesis, as a chemic...
T2S1635 3-Isomangostin MTH1
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac...
TWP2911 Thymidine 5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin Others , DNA/RNA Synthesis , Endogenous Metabolite
1. Thymidine (DThyd) overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues.
T5270 5-Methylcytosine Others , DNA/RNA Synthesis , Endogenous Metabolite
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated...
T5901 3-Hydroxy-2-methylpyridine Others
3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.
TN1134 Euscaphic acid Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor
Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of...
T3606 γ-Oryzanol Gamma-Oryzanol,Oliver,Gammariza DNA Methyltransferase
γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in the skin. It has recently b...
T3717 Hinokitiol 4-Isopropyltropolone,β-thujaplicin DNA Methyltransferase , Virus Protease , Estrogen/progestogen Receptor , Nrf2
Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent...
T7457 5-Methyl-2'-deoxycytidine 5-Methyldeoxycytidine,5MedCyd DNA Methyltransferase , Endogenous Metabolite
5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.
T6567 Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin Topoisomerase , Antibacterial , Antibiotic
Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.
TN3110 5-Geranoxy-7-methoxycoumarin Anti-infection , Antibacterial , Antifungal
5-Geranoxy-7-methoxycoumarin shows antifungal activity.
T35455 N-Nitrosodiethylamine Diethylnitrosamine,NDEA DNA/RNA Synthesis
N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitroso...
TQ0184 Chebulinic acid ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
T6S0232 Eriodictyol Huazhongilexone Influenza Virus , DNA/RNA Synthesis , Nrf2 , Endogenous Metabolite
1. Eriodictyol (Huazhongilexone) is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance. 3....
T1508 Decitabine Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine Apoptosis , Nucleoside Antimetabolite/Analog , DNA Methyltransferase
Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis...
T6225 Adenine hydrochloride Adenine HCl,6-Aminopurine hydrochloride DNA/RNA Synthesis , Endogenous Metabolite
Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.
T0974 Novobiocin Sodium Albamycinsodium,Cathomycin,Albamycin Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim...
T1507 Streptozocin STZ,Streptozotocin,NSC-85998,U 9889 DNA Alkylator/Crosslinker , DNA Alkylation , DNA/RNA Synthesis , Antibacterial , Antibiotic , Autophagy
Streptozocin (NSC-85998) is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
T6369 Adenine hemisulfate Diadenine sulphate,Adenine sulfate,Adeninsulfat DNA/RNA Synthesis , Endogenous Metabolite
Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.
T13229 Tunicamycin Influenza Virus , Antibacterial , Antibiotic , Antifungal
Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT). Tunicamycin has antitumor activity, as well as anti-bacterial, anti-fungal, and anti-viral activity...
T1339 5-Azacytidine Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-AzaC Nucleoside Antimetabolite/Analog , DNA Methyltransferase , Antibacterial , Antibiotic , Autophagy
5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity. 5-Azacytidine regulates gene expression by decreasing the level of DNA methylation. 5-Azacytidine induces autopha...
T16674 Pseudouridine Endogenous Metabolite
Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.
T3332 Isosteviol (-)-Isosteviol IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio...
TN1637 Eurycomalactone Anti-infection , NF-κB
Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-in...
T4593 ISOPIMPINELLIN 5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen Antiviral , DNA/RNA Synthesis , Parasite
Isopimpinellin (4,9-Dimethoxypsoralen) is a natural product isolated from the roots of Pimpinella saxifrage with antiviral and antileishmanial activity.
T9715 Aplidine SARS-CoV , DNA/RNA Synthesis
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM).
T2998 Dihydromyricetin Ampelopsin,Ampeloptin Influenza Virus , GABA Receptor , DNA/RNA Synthesis , mTOR , Autophagy
Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of 48 μM. Dihydromyricetin can activate autophagy...
TWS1977 Kamebakaurin Kamebakaurine NF-κB
1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...
T4558 Trioxsalen Trimethylpsoralen,Trioxysalen,Trisoralen DNA Alkylator/Crosslinker , DHFR
Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, wh...
T6995 Ochromycinone STA 21,STA21,STA-21 Antibacterial , STAT
Ochromycinone (STA 21) is a selective STAT3 inhibitor.
T13791 N2-methylguanine N2-methylguanine DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial
N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside.
T7004 Tubercidin Sparsomycin A,7-Deazaadenosine Influenza Virus , DNA/RNA Synthesis , Antibacterial , Antibiotic
Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhib...
T5368 Eicosapentaenoic Acid Histone Demethylase , Others , Endogenous Metabolite
Eicosapentaenoic Acid (EPA) is a ω-3 fatty acid abundantly available in marine organisms.
T40426 Cytidine 5'-diphosphate trisodium salt CDP Others
Cytidine 5'-diphosphate trisodium salt (CDP) can produce Cytidine triphosphate for synthesis of DNA and RNA through the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosp...
T6758 Anisomycin Flagecidin,NSC 76712,Wuningmeisu C Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK
Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
T6116 Bleomycin Sulfate Blenoxane,NSC125066 DNA/RNA Synthesis , Antibiotic
Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity.
TN1097 β-Boswellic acid Beta-boswellic acid Lipoxygenase , DNA/RNA Synthesis
β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities.
T0909 Nalidixic acid NSC-82174 Topoisomerase , Antibacterial , Antibiotic
Nalidixic acid (NSC-82174) is a synthetic 1, 8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
T8130 Ciprofloxacin hydrochloride monohydrate Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,Ceprimax,Ciloxan Antibacterial , Antibiotic
Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic,is an antibiotic used to treat a number of bacterial infections
T7174 Urolithin A Apoptosis , Reactive Oxygen Species , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , Drug Metabolite
Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties.
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Natural Products

Calf thymus DNA
T13592
Synonym: DNA from calf thymus, Thymonucleic acid
Target: DNA/RNA Synthesis
Phleomycin
T21498
Synonym:
Target: DNA/RNA Synthesis, Antibacterial, Antibiotic
1-Hydroxyanthraquinone
T37101
Synonym:
Target: DNA/RNA Synthesis
Dithranol
T1068
Synonym: 1,8,9-trihydroxyanthracene,cignoline,Anthralin
Target: Others, DNA/RNA Synthesis
Deoxycytidine triphosphate
T7520
Synonym:
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite
Xanthopterin (hydrate)
T13969
Synonym:
Target: Others, DNA/RNA Synthesis
Neobavaisoflavone
T6S0139
Synonym:
Target: Apoptosis, DNA/RNA Synthesis
Quinizarin
TN2132
Synonym: 1,4-Dihydroxyanthraquinone
Target: Others, DNA/RNA Synthesis, Antifungal
Sodium Camptothecin
T40179
Synonym:
Target: DNA/RNA Synthesis
Rabdosiin
T12651
Synonym: (+)-Rabdosiin
Target: Others
Adenine
T0064
Synonym: Vitamin B4,6-Aminopurine
Target: DNA/RNA Synthesis, Endogenous Metabolite, AChR
3-Isomangostin
T2S1635
Synonym:
Target: MTH1
Thymidine
TWP2911
Synonym: 5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin
Target: Others, DNA/RNA Synthesis, Endogenous Metabolite
5-Methylcytosine
T5270
Synonym:
Target: Others, DNA/RNA Synthesis, Endogenous Metabolite
3-Hydroxy-2-methylpyridine
T5901
Synonym:
Target: Others
Euscaphic acid
TN1134
Synonym:
Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor
γ-Oryzanol
T3606
Synonym: Gamma-Oryzanol,Oliver,Gammariza
Target: DNA Methyltransferase
Hinokitiol
T3717
Synonym: 4-Isopropyltropolone,β-thujaplicin
Target: DNA Methyltransferase, Virus Protease, Estrogen/progestogen Receptor, Nrf2
5-Methyl-2'-deoxycytidine
T7457
Synonym: 5-Methyldeoxycytidine,5MedCyd
Target: DNA Methyltransferase, Endogenous Metabolite
Levofloxacin
T6567
Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin
Target: Topoisomerase, Antibacterial, Antibiotic
5-Geranoxy-7-methoxycoumarin
TN3110
Synonym:
Target: Anti-infection, Antibacterial, Antifungal
N-Nitrosodiethylamine
T35455
Synonym: Diethylnitrosamine,NDEA
Target: DNA/RNA Synthesis
Chebulinic acid
TQ0184
Synonym:
Target: ATPase, Proton pump, DNA/RNA Synthesis, Antibacterial, TGF-beta/Smad
Eriodictyol
T6S0232
Synonym: Huazhongilexone
Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite
Decitabine
T1508
Synonym: Dacogen,NSC 127716,Deoxycytidine,5-Aza-2'-deoxycytidine
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA Methyltransferase
Adenine hydrochloride
T6225
Synonym: Adenine HCl,6-Aminopurine hydrochloride
Target: DNA/RNA Synthesis, Endogenous Metabolite
Novobiocin Sodium
T0974
Synonym: Albamycinsodium,Cathomycin,Albamycin
Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy
Streptozocin
T1507
Synonym: STZ,Streptozotocin,NSC-85998,U 9889
Target: DNA Alkylator/Crosslinker, DNA Alkylation, DNA/RNA Synthesis, Antibacterial, Antibiotic, Autophagy
Adenine hemisulfate
T6369
Synonym: Diadenine sulphate,Adenine sulfate,Adeninsulfat
Target: DNA/RNA Synthesis, Endogenous Metabolite
Tunicamycin
T13229
Synonym:
Target: Influenza Virus, Antibacterial, Antibiotic, Antifungal
5-Azacytidine
T1339
Synonym: Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-AzaC
Target: Nucleoside Antimetabolite/Analog, DNA Methyltransferase, Antibacterial, Antibiotic, Autophagy
Pseudouridine
T16674
Synonym:
Target: Endogenous Metabolite
Isosteviol
T3332
Synonym: (-)-Isosteviol
Target: IL Receptor, Potassium Channel, TNF, NF-κB, Reactive Oxygen Species, COX, Topoisomerase
Eurycomalactone
TN1637
Synonym:
Target: Anti-infection, NF-κB
ISOPIMPINELLIN
T4593
Synonym: 5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen
Target: Antiviral, DNA/RNA Synthesis, Parasite
Aplidine
T9715
Synonym:
Target: SARS-CoV, DNA/RNA Synthesis
Dihydromyricetin
T2998
Synonym: Ampelopsin,Ampeloptin
Target: Influenza Virus, GABA Receptor, DNA/RNA Synthesis, mTOR, Autophagy
Kamebakaurin
TWS1977
Synonym: Kamebakaurine
Target: NF-κB
Trioxsalen
T4558
Synonym: Trimethylpsoralen,Trioxysalen,Trisoralen
Target: DNA Alkylator/Crosslinker, DHFR
Ochromycinone
T6995
Synonym: STA 21,STA21,STA-21
Target: Antibacterial, STAT
N2-methylguanine
T13791
Synonym: N2-methylguanine
Target: DNA/RNA Synthesis, Endogenous Metabolite, Antibacterial
Tubercidin
T7004
Synonym: Sparsomycin A,7-Deazaadenosine
Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic
Eicosapentaenoic Acid
T5368
Synonym:
Target: Histone Demethylase, Others, Endogenous Metabolite
Cytidine 5'-diphosphate trisodium salt
T40426
Synonym: CDP
Target: Others
Anisomycin
T6758
Synonym: Flagecidin,NSC 76712,Wuningmeisu C
Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, JNK
Bleomycin Sulfate
T6116
Synonym: Blenoxane,NSC125066
Target: DNA/RNA Synthesis, Antibiotic
β-Boswellic acid
TN1097
Synonym: Beta-boswellic acid
Target: Lipoxygenase, DNA/RNA Synthesis
Nalidixic acid
T0909
Synonym: NSC-82174
Target: Topoisomerase, Antibacterial, Antibiotic
Ciprofloxacin hydrochloride monohydrate
T8130
Synonym: Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,Ceprimax,Ciloxan
Target: Antibacterial, Antibiotic
Urolithin A
T7174
Synonym:
Target: Apoptosis, Reactive Oxygen Species, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, Drug Metabolite

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00792 DNA PolymeraseBeta Protein, Human, Recombinant (His) Human E. coli
Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-p...
TMPH-00523 DNA-directed DNA polymerase Protein, Enterobacteria phage RB69, Recombinant (His & Myc) Escherichia phage RB69 E. coli
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
TMPH-00427 DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant Colwellia psychrerythraea E. coli
TMPH-00611 DNA helicase II Protein, E. coli, Recombinant E. coli E. coli
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
TMPH-00475 DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His) Desulfotalea psychrophila E. coli
Releases the N-terminal proline from various substrates. Cleaves specifically Pro-betaNA and small peptides containing proline at the amino terminal. No activity against hydroxyproline-betaNA.
TMPH-00425 DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His) Colwellia psychrerythraea E. coli
TMPH-00426 DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His) Colwellia psychrerythraea E. coli
TMPH-00476 DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc) Dictyostelium discoideum E. coli
Cleaves asparagine-linked oligomannose and hybrid, but not complex, oligosaccharides from glycoproteins.
TMPH-00898 Human adenovirus C serotype 5 DNA-binding protein (His) HAdV-5 Baculovirus
TMPH-03614 DNA photolyase Protein, Synechococcus sp., Recombinant (His & Myc & SUMO) Synechococcus sp. E. coli
TMPH-00360 DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant Cenarchaeum symbiosum E. coli
TMPH-00613 DNA polymerase II Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
TMPH-03487 DNA-binding protein H-NS Protein, SerRatia marcescens, Recombinant (His) Serratia marcescens E. coli
A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction. Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensi...
TMPH-00616 DNA-binding protein H-NS Protein, E. coli, Recombinant (His) E. coli E. coli
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosph...
TMPH-00896 Human adenovirus C serotype 2 DNA-binding protein (His) HAdV-2 E. coli
TMPJ-00457 OGG1 Protein, Human, Recombinant Human E. coli
Human N-Glycosylase/DNA Lyase(OOG1) is a DNA repair enzyme, which belongs to the type-1 OGG1 family. OOG1 incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamido...
TMPH-00039 Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc) Agrobacterium fabrum E. coli
TMPJ-00872 MGMT Protein, Human, Recombinant (His) Human E. coli
MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs al...
TMPH-00524 ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His) Enterobacteria phage T4 E. coli
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocy...
TMPY-03601 PDRG1 Protein, Human, Recombinant (His) Human E. coli
PDRG1, also known as C2orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chapero...
TMPH-00668 DNA-binding protein HU-alpha Protein, E. coli O157:H7, Recombinant (His & SUMO) E. coli E. coli
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.
TMPY-02150 GADD45A Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
GADD45A is a member of the GADD45 Family, and has been found to associate with several cytoplasmic and nuclear factors and has been implicated in several cellular functions, including MAPK signaling, cell cycle regulatio...
TMPJ-00483 DFF45 Protein, Human, Recombinant (His) Human E. coli
DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF...
TMPJ-00907 GADD45A Protein, Human, Recombinant (His) Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 α (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some ...
TMPJ-00711 GADD45G Protein, Human, Recombinant (His) Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript...
TMPY-03655 GADD45G Protein, Human, Recombinant Human E. coli
GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G re...
TMPJ-00765 TDT Protein, Human, Recombinant (His) Human E. coli
Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5'-triphosphates onto the 3'-hydroxyl group of a si...
TMPH-01450 Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) DNA polymerase processivity factor (His) HHV-6A Yeast
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of ...
TMPJ-01061 Nucleobindin-2 Protein, Human, Recombinant Human E. coli
Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulat...
TMPY-02000 UNG Protein, Human, Recombinant (GST) Human E. coli
Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. Uracil-DNA glycosylase exists in t...
TMPJ-01328 ZBP1 Protein, Human, Recombinant (His) Human E. coli
Z-DNA Binding Protein 1 (ZBP1) is a protein with 2 DRADA repeats. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow, and spleen. ZBP1 participates in the detection of vir...
TMPY-02420 HEMK2 Protein, Human, Recombinant (His) Human E. coli
N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes an N(6)-adenine-specific DNA methyltransferase. It belongs to t...
TMPJ-00887 NFKB1 Protein, Human, Recombinant (His) Human E. coli
The 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radica...
TMPJ-00903 NFYA Protein, Human, Recombinant Human E. coli
Nuclear Transcription Factor Y Subunit α (NFYA) is a member of the NFYA/HAP2 subunit family. NFYA founctions as a heterotrimeric transcription factor , which is composed of three components, NF-YA, NF-YB and NF-YC, binds...
TMPJ-01241 DTD1 Protein, Human, Recombinant (His) Human Human Cells
D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is...
TMPY-02433 APE1/APEX1 Protein, Human, Recombinant (His) Human E. coli
The enzyme is known to be a redox factor (Ref-1) stimulating DNA binding activity of AP-1 binding proteins such as Fos and Jun as well as a multifunctional DNA repair enzyme having 5' AP endonuclease, DNA 3' repair diest...
TMPJ-00904 NFYA Protein, Human, Recombinant (GST) Human E. coli
Nuclear Transcription Factor Y Subunit α (NFYA) is a member of the NFYA/HAP2 subunit family. NFYA founctions as a heterotrimeric transcription factor , which is composed of three components, NF-YA, NF-YB and NF-YC, binds...
TMPJ-00700 GADD45B Protein, Human, Recombinant (His) Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of g...
TMPJ-00705 BCAS2 Protein, Human, Recombinant (His, T7) Human E. coli
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell li...
TMPJ-00464 APE Protein, Human, Recombinant Human E. coli
Apurinic-Apyrimidinic Endonuclease 1 (APE1) is required for efficient DNA base excision repair. When the DNA glycosylase remove the damaged bases, APE1 cleaves the AP site to allow resynthesis and ligation to complete re...
TMPY-02287 Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
X-ray repair cross-complementing protein 5, also known as 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 8 kDa subunit, CTC box-binding factor 85 kDa subunit, DNA repa...
TMPY-01188 PARP Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Poly (ADP-ribose) polymerase 1(PRAP1), also known as NAD(+) ADP-ribosyltransferase 1(ADPRT), is a chromatin-associated enzyme that modifies various nuclear proteins by poly(ADP-ribosyl)ation. The ADP-D-ribosyl group of N...
TMPY-03195 Serum Amyloid P Protein, Human, Recombinant (His) Human HEK293
Serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a highly preserved plasma protein named for its ubiquitous presence in amyloid deposits. As a normal plasma protein first identifie...
TMPY-02953 TEM8/ANTXR1 Protein, Human, Recombinant (hFc) Human HEK293
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are ser...
TMPY-03855 DNase I Protein, Human, Recombinant (His) Human HEK293
DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phos...
TMPY-02521 HIST3H2A Protein, Human, Recombinant Human E. coli
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident ...
TMPH-00007 HMGCR Protein, Human, Recombinant (His) Human E. coli
The production of this recombinant Human HMGCR protein is just like all recombinant proteins. The process involved transfecting E.coli cells with DNA vector containing the template of recombinant DNA. The E.coli cells co...
TMPY-04356 GSK3B Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ...
TMPY-04376 PLK1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Serine / threonine-protein kinase PLK1 / PLK-1, also known as polo-like kinase 1 (PLK-1) or serine / threonine-protein kinase 13 (STPK13), Polo-like kinases (PLKs), is a family of four serine / threonine protein kinases ...
TMPY-00541 LON PROTEASE Protein, E. coli, Recombinant (His) E. coli E. coli
Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and natura...
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DNA PolymeraseBeta Protein, Human, Recombinant (His)
TMPJ-00792
Species: Human
Expression System: E. coli
DNA-directed DNA polymerase Protein, Enterobacteria phage RB69, Recombinant (His & Myc)
TMPH-00523
Species: Escherichia phage RB69
Expression System: E. coli
DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant
TMPH-00427
Species: Colwellia psychrerythraea
Expression System: E. coli
DNA helicase II Protein, E. coli, Recombinant
TMPH-00611
Species: E. coli
Expression System: E. coli
DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His)
TMPH-00475
Species: Desulfotalea psychrophila
Expression System: E. coli
DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His)
TMPH-00425
Species: Colwellia psychrerythraea
Expression System: E. coli
DNA polymerase IV Protein, Colwellia psychrerythraea, Recombinant (His)
TMPH-00426
Species: Colwellia psychrerythraea
Expression System: E. coli
DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc)
TMPH-00476
Species: Dictyostelium discoideum
Expression System: E. coli
Human adenovirus C serotype 5 DNA-binding protein (His)
TMPH-00898
Species: HAdV-5
Expression System: Baculovirus
DNA photolyase Protein, Synechococcus sp., Recombinant (His & Myc & SUMO)
TMPH-03614
Species: Synechococcus sp.
Expression System: E. coli
DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant
TMPH-00360
Species: Cenarchaeum symbiosum
Expression System: E. coli
DNA polymerase II Protein, E. coli, Recombinant (His & Myc)
TMPH-00613
Species: E. coli
Expression System: E. coli
DNA-binding protein H-NS Protein, SerRatia marcescens, Recombinant (His)
TMPH-03487
Species: Serratia marcescens
Expression System: E. coli
DNA-binding protein H-NS Protein, E. coli, Recombinant (His)
TMPH-00616
Species: E. coli
Expression System: E. coli
Human adenovirus C serotype 2 DNA-binding protein (His)
TMPH-00896
Species: HAdV-2
Expression System: E. coli
OGG1 Protein, Human, Recombinant
TMPJ-00457
Species: Human
Expression System: E. coli
Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc)
TMPH-00039
Species: Agrobacterium fabrum
Expression System: E. coli
MGMT Protein, Human, Recombinant (His)
TMPJ-00872
Species: Human
Expression System: E. coli
ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His)
TMPH-00524
Species: Enterobacteria phage T4
Expression System: E. coli
PDRG1 Protein, Human, Recombinant (His)
TMPY-03601
Species: Human
Expression System: E. coli
DNA-binding protein HU-alpha Protein, E. coli O157:H7, Recombinant (His & SUMO)
TMPH-00668
Species: E. coli
Expression System: E. coli
GADD45A Protein, Human, Recombinant (His & GST)
TMPY-02150
Species: Human
Expression System: Baculovirus-Insect Cells
DFF45 Protein, Human, Recombinant (His)
TMPJ-00483
Species: Human
Expression System: E. coli
GADD45A Protein, Human, Recombinant (His)
TMPJ-00907
Species: Human
Expression System: E. coli
GADD45G Protein, Human, Recombinant (His)
TMPJ-00711
Species: Human
Expression System: E. coli
GADD45G Protein, Human, Recombinant
TMPY-03655
Species: Human
Expression System: E. coli
TDT Protein, Human, Recombinant (His)
TMPJ-00765
Species: Human
Expression System: E. coli
Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) DNA polymerase processivity factor (His)
TMPH-01450
Species: HHV-6A
Expression System: Yeast
Nucleobindin-2 Protein, Human, Recombinant
TMPJ-01061
Species: Human
Expression System: E. coli
UNG Protein, Human, Recombinant (GST)
TMPY-02000
Species: Human
Expression System: E. coli
ZBP1 Protein, Human, Recombinant (His)
TMPJ-01328
Species: Human
Expression System: E. coli
HEMK2 Protein, Human, Recombinant (His)
TMPY-02420
Species: Human
Expression System: E. coli
NFKB1 Protein, Human, Recombinant (His)
TMPJ-00887
Species: Human
Expression System: E. coli
NFYA Protein, Human, Recombinant
TMPJ-00903
Species: Human
Expression System: E. coli
DTD1 Protein, Human, Recombinant (His)
TMPJ-01241
Species: Human
Expression System: Human Cells
APE1/APEX1 Protein, Human, Recombinant (His)
TMPY-02433
Species: Human
Expression System: E. coli
NFYA Protein, Human, Recombinant (GST)
TMPJ-00904
Species: Human
Expression System: E. coli
GADD45B Protein, Human, Recombinant (His)
TMPJ-00700
Species: Human
Expression System: E. coli
BCAS2 Protein, Human, Recombinant (His, T7)
TMPJ-00705
Species: Human
Expression System: E. coli
APE Protein, Human, Recombinant
TMPJ-00464
Species: Human
Expression System: E. coli
Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His)
TMPY-02287
Species: Human
Expression System: Baculovirus-Insect Cells
PARP Protein, Human, Recombinant (His)
TMPY-01188
Species: Human
Expression System: Baculovirus-Insect Cells
Serum Amyloid P Protein, Human, Recombinant (His)
TMPY-03195
Species: Human
Expression System: HEK293
TEM8/ANTXR1 Protein, Human, Recombinant (hFc)
TMPY-02953
Species: Human
Expression System: HEK293
DNase I Protein, Human, Recombinant (His)
TMPY-03855
Species: Human
Expression System: HEK293
HIST3H2A Protein, Human, Recombinant
TMPY-02521
Species: Human
Expression System: E. coli
HMGCR Protein, Human, Recombinant (His)
TMPH-00007
Species: Human
Expression System: E. coli
GSK3B Protein, Human, Recombinant (His)
TMPY-04356
Species: Human
Expression System: Baculovirus-Insect Cells
PLK1 Protein, Human, Recombinant (His)
TMPY-04376
Species: Human
Expression System: Baculovirus-Insect Cells
LON PROTEASE Protein, E. coli, Recombinant (His)
TMPY-00541
Species: E. coli
Expression System: E. coli
Cat No. Product Name
L3900 DNA Damage & Repair Compound Library

937 compounds
A unique collection of 937 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);
L3980 DNA Damage and Repair Compound Library Plus

667 compounds
Well-chosen 667 compounds with unique structures targeting DNA damage & repair;
L3510 Methylation Compound Library

131 compounds
131 methylation-related compounds that can be used for high-throughput and high-content screening.
L1200 Epigenetics Compound Library

960 compounds
Well-chosen 960 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L1380 Transcription Factor-Targeted Compound Library

704 compounds
Well-chosen 704 compounds with unique structures targeting transcription factor;
L5500 Toxic Compound Library

277 compounds
A unique collection of 277 toxic substances for high throughput screening (HTS) and high content screening (HCS);
L3800 NF-κB Signaling Compound Library

740 compounds
A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L8100 Cell Cycle Compound Library

695 compounds
A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
L8300 Chromatin Modification Compound Library

256 compounds
A unique collection of 256 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS);
L1510 Nuclear Receptor Compound Library

546 compounds
A unique collection of 546 nuclear receptor signaling targeted compounds for high throughput and high content screening;
L3500 Histone Modification Compound Library

480 compounds
A unique collection of 480 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
L8600 Ubiquitination Compound Library

214 compounds
A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening;
L5300 Mitochondria-Targeted Compound Library

830 compounds
A unique collection of 830 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
L2910 Antioxidant Compound Library

1330 compounds
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ...
L6120 Flavonoid Natural Product Library

477 compounds
A unique collection of 477 flavonoids can be used for high throughput and high content screening;
TargetMol