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Search Results for " erk "

221

Compounds

72

Natural Products

71

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T9141 ERK-IN-3 ASN007 free base ERK
ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.
T36675 ERK Inhibitor
ERK inhibitor is a cell-permeable inhibitor that binds ERK2 near its docking domain (KD = 5 μM). This prevents its interaction with protein substrates without inhibiting catalytic activity. ERK inhibitor blocks ERK-speci...
T11224 Rineterkib ERK-IN-1 ERK , Raf
Rineterkib (ERK-IN-1) is an inhibitor of RAF and ERK1/2 activating mutations in the MAPK pathway.
T11225 ERK-IN-2 ERK
ERK-IN-2 is a ERK2 inhibitor with an IC 50 value of 1.8 nM. ERK-IN-2 might cause off-target toxicity and/or off-target activity at dose >10 μM [1].
T39453 ERK-IN-3 benzenesulfonate
ERK-IN-3 benzenesulfonate is a potent and orally active inhibitor of ERK . ERK-IN-3 benzenesulfonate inhibits ERK1/2 with low single-digit nM IC 50 values. ERK-IN-3 benzenesulfonate can be used for the research of cancer...
T3166 VX-11e Vertex-11e,VTX-11e,TCS ERK 11e ERK , GSK-3 , FLT , CDK , Aurora Kinase
VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.
T74997 ERK-IN-6
ERK-IN-6 (compound 6g) is an potent anti-proliferation agent against esophageal squamous cell carcinoma ( ESCC ). ERK-IN-6 induces cell apoptosis via ERK pathway. ERK-IN-6 can be used for the research of ESCC [1] .
T82443 ERK-CLIPTAC PROTACs
ERK-CLIPTAC is a PROTAC (PROteolysis TArgeting Chimera) molecule designed to induce the degradation of Extracellular signal-Regulated Kinase (ERK) [1].
T71316 ERK Inhibitor II (Negative control)
ERK Inhibitor II (Negative control) is an effective inhibitor of extracellular signal-regulated kinase ( ERK ). ERK Inhibitor II (Negative control) inhibits the activation of insulin receptor , which can be used in the s...
T72517 ERK-IN-2 free base
ERK-IN-2 free base is a ERK2 inhibitor with an IC 50 value of 1.8 nM. ERK-IN-2 free base might lead to off-target toxicity and/or off-target activity at dose >10 μM .
T5184 ERK5-IN-1 ERK
ERK5-IN-1 is a potent ERK5 inhibitor (IC50: 87 nM). It also inhibits LRRK2[G2019S] (IC50: 26 nM).
T5535 ERK5-IN-2 ERK
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively.
T80543 STE-MEK1(13) ERK Activation Inhibitor Peptide,Ste-MPKKKPTPIQLNP-NH₂ ERK
STE-MEK1(13), a cell-permeable ERK1/2 inhibitor with IC50 values ranging from 13 to 30 μM, impedes the phosphorylation of ERK1/2, as demonstrated in studies [1] [2].
T8472 ERK1/2 inhibitor 2 ASTX-029,ASTX029 ERK
ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable extracellular signal-regulated kinases 1 and 2 (ERK 1/2) inhibitor, with potential antineoplastic activity.
T11226 ERK1/2 inhibitor 1 ERK
ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.
T5358 Longdaysin ERK , Casein Kinase , CDK
Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 µM). It also can inhibit ERK2 (IC50: 52 µM).
T4091 Temuterkib LY3214996 ERK
Temuterkib (LY3214996) is a potent and selective, orally available inhibitor of the extracellular signal-regulated kinase (ERK) 1 and 2, with potential antineoplastic activity.
T14894 CC-90003 ERK
CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.
T6066 SCH772984 ERK , MEK
SCH 772984 is a potent inhibitor of ERK1/ERK2 (IC50: 4/1 nM) and has only weak inhibitory for other 300 tested kinases.
TQ0005 KO-947 ERK
KO-947 is a potent and specific inhibitor of ERK1/2 kinases.
T14360 AX-15836 ERK
AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).
T10479 BAY885 ERK
BAY885 is a new ERK5 inhibitor.
T10429 Tizaterkib AZD-0364 ERK
Tizaterkib (AZD-0364) is a potent and selective ERK2 inhibitor.
T1956 FR 180204 FR180204 Apoptosis , ERK
FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.
T6818 DEL-22379 DEL22379 Apoptosis , ERK
DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ~0.5 μM.
T6511 Ravoxertinib GDC-0994 ERK
Ravoxertinib (GDC-0994) is an effective and orally available ERK1/2 inhibitor (IC50: 1.1/0.3 nM).
T8418 DCLK1-IN-1 Others
DCLK1-IN-1 is a selective and in vivo-compatible chemical probe of the DCLK1 kinase domain .
T4985 Neticonazole Hydrochloride Antifungal
Neticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes.
T36674 DMU-212 Apoptosis , ERK
DMU-212 is a methylated derivative of Resveratrol , with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2...
T16143 MRTX-1257 Ras
MRTX-1257 is a selective, irreversible, and covalent inhibitor of KRAS G12C. It has an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells. MRTX1257 demonstrated 31% bioavailability in the mouse, with fre...
T7953 BpV(HOpic) bpV (HOpic) PTEN
BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM).
T7425 RU-301 TAM Receptor
RU-301 is a novel pan-tam inhibitor
T6948 Pluripotin SC1 ERK , Raf , S6 Kinase
Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP.
T9303 MRTX1133 Ras
MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.
T1843 XMD8-92 ERK , BMI-1 , Epigenetic Reader Domain
XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).
T8973 HS-1793 Others
HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model
T21295 BIX02189 BIX 02189 ERK , MEK
BIX02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and 59 nM).
T21302 UNC569 UNC 569 TAM Receptor
UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amoun...
T12069 MK-8353 SCH900353 ERK
MK-8353 (SCH900353) is a potent, selective and orally available inhibitor of ERK1/2 (IC50s of 23.0 nM and 8.8 nM, respectively)
T2029 Bohemine ERK , CDK
Bohemine is a cyclin-dependent kinase inhibitor.
T1842 XMD17-109 XMD17 109,ERK5-IN-1 ERK
XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).
T4496 LM22B-10 LM22B10 ERK , Trk receptor , Akt
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor and can induce TrkB, TrkC, ERK and AKT activation in vitro and in vivo.
T14042 4-P-PDOT 4-phenyl-2- propionamidotetralin Melatonin Receptor , MT Receptor
4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
T5364 TBHQ tert-Butylhydroquinone Apoptosis , ERK , Others , Ferroptosis , Nrf2 , Autophagy
TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.
T2623 PD98059 PD 98059 ERK , Aryl Hydrocarbon Receptor , MEK , Autophagy
PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive. PD98059 is also antagonistic as a ligand for AHR. PD98059 inhibits autophagy.
T7506 Yoda 1 Piezo Channel
Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 μM for murine and human Piezo1-transfected HEK293T cells, respectively)
T21980 PD 198306 MEK
PD 198306 is a selective inhibitor of MAPK/ERK-kinase (MEK) with antihyperalgesic effects. PD 198306 reduces the Streptozocin-induced increase in the level of active ERK1.
T7005 Ulixertinib BVD-523,VRT752271 ERK
Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.
T7322 Theliatinib EGFR
Theliatinib, a potent and highly selective EGFR inhibitor, with anti-tumor activity. Ki of 0.05 nM for wild type EGFR, and IC50s of 3 and 22 nM for EGFR and EGFR T790M/L858R mutant, respectively.
T8719 SC99 Apoptosis , JAK , STAT
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti...

Compounds

ERK-IN-3
T9141
Synonym: ASN007 free base
Target: ERK
ERK Inhibitor
T36675
Synonym:
Target:
Rineterkib
T11224
Synonym: ERK-IN-1
Target: ERK, Raf
ERK-IN-2
T11225
Synonym:
Target: ERK
ERK-IN-3 benzenesulfonate
T39453
Synonym:
Target:
VX-11e
T3166
Synonym: Vertex-11e,VTX-11e,TCS ERK 11e
Target: ERK, GSK-3, FLT, CDK, Aurora Kinase
ERK-IN-6
T74997
Synonym:
Target:
ERK-CLIPTAC
T82443
Synonym:
Target: PROTACs
ERK Inhibitor II (Negative control)
T71316
Synonym:
Target:
ERK-IN-2 free base
T72517
Synonym:
Target:
ERK5-IN-1
T5184
Synonym:
Target: ERK
ERK5-IN-2
T5535
Synonym:
Target: ERK
STE-MEK1(13)
T80543
Synonym: ERK Activation Inhibitor Peptide,Ste-MPKKKPTPIQLNP-NH₂
Target: ERK
ERK1/2 inhibitor 2
T8472
Synonym: ASTX-029,ASTX029
Target: ERK
ERK1/2 inhibitor 1
T11226
Synonym:
Target: ERK
Longdaysin
T5358
Synonym:
Target: ERK, Casein Kinase, CDK
Temuterkib
T4091
Synonym: LY3214996
Target: ERK
CC-90003
T14894
Synonym:
Target: ERK
SCH772984
T6066
Synonym:
Target: ERK, MEK
KO-947
TQ0005
Synonym:
Target: ERK
AX-15836
T14360
Synonym:
Target: ERK
BAY885
T10479
Synonym:
Target: ERK
Tizaterkib
T10429
Synonym: AZD-0364
Target: ERK
FR 180204
T1956
Synonym: FR180204
Target: Apoptosis, ERK
DEL-22379
T6818
Synonym: DEL22379
Target: Apoptosis, ERK
Ravoxertinib
T6511
Synonym: GDC-0994
Target: ERK
DCLK1-IN-1
T8418
Synonym:
Target: Others
Neticonazole Hydrochloride
T4985
Synonym:
Target: Antifungal
DMU-212
T36674
Synonym:
Target: Apoptosis, ERK
MRTX-1257
T16143
Synonym:
Target: Ras
BpV(HOpic)
T7953
Synonym: bpV (HOpic)
Target: PTEN
RU-301
T7425
Synonym:
Target: TAM Receptor
Pluripotin
T6948
Synonym: SC1
Target: ERK, Raf, S6 Kinase
MRTX1133
T9303
Synonym:
Target: Ras
XMD8-92
T1843
Synonym:
Target: ERK, BMI-1, Epigenetic Reader Domain
HS-1793
T8973
Synonym:
Target: Others
BIX02189
T21295
Synonym: BIX 02189
Target: ERK, MEK
UNC569
T21302
Synonym: UNC 569
Target: TAM Receptor
MK-8353
T12069
Synonym: SCH900353
Target: ERK
Bohemine
T2029
Synonym:
Target: ERK, CDK
XMD17-109
T1842
Synonym: XMD17 109,ERK5-IN-1
Target: ERK
LM22B-10
T4496
Synonym: LM22B10
Target: ERK, Trk receptor, Akt
4-P-PDOT
T14042
Synonym: 4-phenyl-2- propionamidotetralin
Target: Melatonin Receptor, MT Receptor
TBHQ
T5364
Synonym: tert-Butylhydroquinone
Target: Apoptosis, ERK, Others, Ferroptosis, Nrf2, Autophagy
PD98059
T2623
Synonym: PD 98059
Target: ERK, Aryl Hydrocarbon Receptor, MEK, Autophagy
Yoda 1
T7506
Synonym:
Target: Piezo Channel
PD 198306
T21980
Synonym:
Target: MEK
Ulixertinib
T7005
Synonym: BVD-523,VRT752271
Target: ERK
Theliatinib
T7322
Synonym:
Target: EGFR
SC99
T8719
Synonym:
Target: Apoptosis, JAK, STAT
1 2 3 4 5
Cat No. Product Name Synonyms Targets
T6S0655 Corynoxeine ERK
1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.
TN2346 Mogrol ERK , AMPK , STAT
Mogrol is a biometabolite of mogrosides. Mogrol acts via inhibition of the ERK1/2 and STAT3 pathways, or reducing CREB activation and activating AMPK signaling.
T3856 Tenuifoliside A ERK , Others
Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which is mediated by the inhibition of the NF-κB and MAPK pathways.
T3857 Magnolin (+)-Magnolin ERK
Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.
T3844 Deltonin 山药 ERK , Others , Akt , Endogenous Metabolite
Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).
T5S1982 Periplocin Periplocoside Apoptosis , Others
1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato...
TN3967 Epieriocalyxin A ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.
T6947 Piperlongumine PPLGM,Piplartine Apoptosis , ERK , Ferroptosis , Reactive Oxygen Species , ROS , Antibacterial , Autophagy
Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
TL0016 Sulforaphene 油菜 Apoptosis , ERK , EGFR , NF-κB
Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EG...
TN1410 Asperulosidic acid ASPA ERK , NF-κB
Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-a...
T3876 Loureirin B PAI-1 , ERK , Potassium Channel , JNK
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathw...
TN1721 Gypenoside L ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a...
T6S0619 Pachymic acid 3-O-Acetyltumulosic acid ERK , Akt
Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.
T5727 CAFESTOL ERK , NF-κB , COX , PGE Synthase
CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production...
TMS2181 Trans-Zeatin (E)-Zeatin ERK , MEK , Endogenous Metabolite
trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient processing.
T3001 Honokiol NSC 293100 ERK , HCV Protease , MEK , Akt , Autophagy
Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.
T5S0761 Nitidine chloride Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T2973 Astragaloside IV AST-IV,AS-IV MMP , ERK , Estrogen/progestogen Receptor , JNK
Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cel...
T6427 Butein 2’,3,4,4’-tetrahydroxy Chalcone Apoptosis , EGFR , Others , PDE , Autophagy
Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.
T13265 Urolithin B ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...
TN2354 Methylnissolin 3-Hydroxy-9,10-dimethoxyptercarpan ERK , PDGFR
Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.
T5S1058 Triptonide PG 492,NSC 165677 Apoptosis , Wnt/beta-catenin , Autophagy
1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, an...
T2532 Tauroursodeoxycholate Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...
TCS2170 2,5-Dihydroxyacetophenone Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP ERK , NF-κB , Tyrosinase
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...
T6S0117 Avicularin Fenicularin ERK
1. Avicularin (Fenicularin) exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. 2. Avicularin inhibits the accumulation of the intracellular ...
T79951 Piperkadsin A Reactive Oxygen Species
Piperkadsin A effectively inhibits reactive oxygen species (ROS) production, specifically targeting PMA-induced ROS in human polymorphonuclear neutrophils, exhibiting an inhibition concentration (IC50) of 4.3 μM [1].
TN4114 Gardenin A ERK , LDL , MAPK , PKA , PKC
Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects.
T10383 Asatone NF-κB
Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.
TN1786 Isomerazin Isomeranzin ERK , NF-κB , AChE
Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.
T5S0168 Atractylenolide II 2-Atractylenolide,Asterolide Apoptosis , ERK , p38 MAPK , Akt , STAT
1. Atractylenolide II (2-Atractylenolide) has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation , ERK and Akt inactivation, p53 dependent.
T2845 Imperatorin Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen TRP/TRPV Channel , AChR , AChE , NOD
Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
T6S0923 Hypericin Hypericine,Cyclosan Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC
1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL...
T3908 10-Gingerol 10-姜酚,[10]-姜酚 Apoptosis
10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK).
T6S1740 Nardosinone Others
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed t...
T3123 Allicin ERK , IL Receptor , Others , IκB/IKK , p38 MAPK , TNF , ROS , Caspase , Antifection
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth mus...
TN2244 Sulfuretin NF-κB , Autophagy
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr...
TN1880 Lucidenic acid B Lucidenicacid B Apoptosis , Caspase
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito...
T5S0890 Oleandrin Neriostene,Folinerin,Foliandrin Apoptosis , ATPase , Potassium Channel , Sodium Channel
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, ...
T3822 Bellidifolin Bellidifoline,Bellidifolium Others , HIV Protease
Bellidifolin (Bellidifoline) has anti-oxidation, hepatoprotective, anti-inflammatory and antitumor actions, it may contribute to the protective effects associated with nerve injury initiated by hypoxia by mechanisms rela...
TN5888 Toddaculin Others
Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-κB, ERK 1/2, and p38 MAPK signaling pathways, but can in...
TN1557 Decursinol angelate ERK , VEGFR , PKC , JNK
Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion an...
T4518 Licochalcone D ERK , NF-κB
Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect...
T7472 7-Hydroxyflavone P450
7-Hydroxyflavone is a potent inhibitor of CYP1A1 with a Ki value of 0.015 μM and exhibits 6-fold greater selectivity for CYP1A1 over CYP1A2.with anti-inflammatory activity
T3S2344 β,β-Dimethylacrylshikonin Dimethylacrylshikonin,β, β-Dimethylacrylshikonin ERK , HIF/HIF Prolyl-Hydroxylase
1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...
T3824 Jaceosidin Apoptosis , BCL , COX , UGT
Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...
T4S0878 Prunetin Prunusetin ERK , Dehydrogenase , NF-κB
1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...
T6S0525 Farrerol ERK , p38 MAPK , Akt
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3....
TN1222 26-Deoxyactein 27-Deoxyactein,23-epi-26-Deoxyactein NOS , CDK , NO Synthase
23-epi-26-Deoxyactein (27-Deoxyactein) has anti-inflammatory activity, it inhibits nitric oxide production by reducing iNOS expression without affecting activity of the enzyme. It also has anti-cancer activity, it can in...
TN1088 3,​5,​6,​7,​8,​3',​4'-​Heptemthoxyflavone 3,3',4',5,6,7,8-heptamethoxyflavone Others
3,5,6,7,8,3',4'-Heptemthoxyflavone has neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging and photoprotective effects; it inhibits collagenase activity and induces type I pro...
T2940 6-Hydroxyflavone 6-HF GABA Receptor
6-Hydroxyflavone (6-HF) is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It is reported in leaves of Barleria prionitis Linn. (a common Acanthaceae from India). 6-Hydro...
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Natural Products

Corynoxeine
T6S0655
Synonym:
Target: ERK
Mogrol
TN2346
Synonym:
Target: ERK, AMPK, STAT
Tenuifoliside A
T3856
Synonym:
Target: ERK, Others
magnolin
T3857
Synonym: (+)-Magnolin
Target: ERK
Deltonin
T3844
Synonym: 山药
Target: ERK, Others, Akt, Endogenous Metabolite
Periplocin
T5S1982
Synonym: Periplocoside
Target: Apoptosis, Others
Epieriocalyxin A
TN3967
Synonym:
Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK
Piperlongumine
T6947
Synonym: PPLGM,Piplartine
Target: Apoptosis, ERK, Ferroptosis, Reactive Oxygen Species, ROS, Antibacterial, Autophagy
Sulforaphene
TL0016
Synonym: 油菜
Target: Apoptosis, ERK, EGFR, NF-κB
Asperulosidic acid
TN1410
Synonym: ASPA
Target: ERK, NF-κB
Loureirin B
T3876
Synonym:
Target: PAI-1, ERK, Potassium Channel, JNK
Gypenoside L
TN1721
Synonym:
Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS
Pachymic acid
T6S0619
Synonym: 3-O-Acetyltumulosic acid
Target: ERK, Akt
CAFESTOL
T5727
Synonym:
Target: ERK, NF-κB, COX, PGE Synthase
trans-Zeatin
TMS2181
Synonym: (E)-Zeatin
Target: ERK, MEK, Endogenous Metabolite
Honokiol
T3001
Synonym: NSC 293100
Target: ERK, HCV Protease, MEK, Akt, Autophagy
Nitidine chloride
T5S0761
Synonym:
Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite
Astragaloside IV
T2973
Synonym: AST-IV,AS-IV
Target: MMP, ERK, Estrogen/progestogen Receptor, JNK
Butein
T6427
Synonym: 2’,3,4,4’-tetrahydroxy Chalcone
Target: Apoptosis, EGFR, Others, PDE, Autophagy
Urolithin B
T13265
Synonym:
Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK
Methylnissolin
TN2354
Synonym: 3-Hydroxy-9,10-dimethoxyptercarpan
Target: ERK, PDGFR
Triptonide
T5S1058
Synonym: PG 492,NSC 165677
Target: Apoptosis, Wnt/beta-catenin, Autophagy
Tauroursodeoxycholate
T2532
Synonym: Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA
Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite
2,5-Dihydroxyacetophenone
TCS2170
Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP
Target: ERK, NF-κB, Tyrosinase
Avicularin
T6S0117
Synonym: Fenicularin
Target: ERK
Piperkadsin A
T79951
Synonym:
Target: Reactive Oxygen Species
Gardenin A
TN4114
Synonym:
Target: ERK, LDL, MAPK, PKA, PKC
Asatone
T10383
Synonym:
Target: NF-κB
Isomerazin
TN1786
Synonym: Isomeranzin
Target: ERK, NF-κB, AChE
Atractylenolide II
T5S0168
Synonym: 2-Atractylenolide,Asterolide
Target: Apoptosis, ERK, p38 MAPK, Akt, STAT
Imperatorin
T2845
Synonym: Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen
Target: TRP/TRPV Channel, AChR, AChE, NOD
Hypericin
T6S0923
Synonym: Hypericine,Cyclosan
Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC
10-Gingerol
T3908
Synonym: 10-姜酚,[10]-姜酚
Target: Apoptosis
Nardosinone
T6S1740
Synonym:
Target: Others
Allicin
T3123
Synonym:
Target: ERK, IL Receptor, Others, IκB/IKK, p38 MAPK, TNF, ROS, Caspase, Antifection
Sulfuretin
TN2244
Synonym:
Target: NF-κB, Autophagy
Lucidenic acid B
TN1880
Synonym: Lucidenicacid B
Target: Apoptosis, Caspase
Oleandrin
T5S0890
Synonym: Neriostene,Folinerin,Foliandrin
Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel
Bellidifolin
T3822
Synonym: Bellidifoline,Bellidifolium
Target: Others, HIV Protease
Toddaculin
TN5888
Synonym:
Target: Others
Decursinol angelate
TN1557
Synonym:
Target: ERK, VEGFR, PKC, JNK
Licochalcone D
T4518
Synonym:
Target: ERK, NF-κB
7-Hydroxyflavone
T7472
Synonym:
Target: P450
β,β-Dimethylacrylshikonin
T3S2344
Synonym: Dimethylacrylshikonin,β, β-Dimethylacrylshikonin
Target: ERK, HIF/HIF Prolyl-Hydroxylase
Jaceosidin
T3824
Synonym:
Target: Apoptosis, BCL, COX, UGT
Prunetin
T4S0878
Synonym: Prunusetin
Target: ERK, Dehydrogenase, NF-κB
Farrerol
T6S0525
Synonym:
Target: ERK, p38 MAPK, Akt
26-Deoxyactein
TN1222
Synonym: 27-Deoxyactein,23-epi-26-Deoxyactein
Target: NOS, CDK, NO Synthase
3,​5,​6,​7,​8,​3',​4'-​Heptemthoxyflavone
TN1088
Synonym: 3,3',4',5,6,7,8-heptamethoxyflavone
Target: Others
6-Hydroxyflavone
T2940
Synonym: 6-HF
Target: GABA Receptor

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04539 ERK2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, diffe...
TMPY-04386 EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) Human Baculovirus-Insect Cells
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5...
TMPY-00784 EphB2 Protein, Human, Recombinant (His & hFc) Human HEK293
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5...
TMPY-03621 EphB2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5...
TMPY-01067 EphB2 Protein, Human, Recombinant (His) Human HEK293
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5...
TMPY-04430 P38 gamma/MAPK12 Protein, Human, Recombinant Human Baculovirus-Insect Cells
ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/t...
TMPY-04429 P38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/t...
TMPY-04216 EphB2 Protein, Mouse, Recombinant (His) Mouse HEK293
Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5...
TMPY-04571 ERK2 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, diffe...
TMPK-00563 EPHB2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated p...
TMPJ-01464 IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F) Human Human Cells
Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m...
TMPY-03564 TSPAN8 Protein, Human, Recombinant (His) Human HEK293
Tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional regulators, which affect TSPAN8 expression during melanoma progression toward an invasive stage. p53 as a nega...
TMPY-04572 MKK4 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPY-05592 ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated Human HEK293
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPY-02333 ULBP-2 Protein, Human, Recombinant (His) Human HEK293
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPY-04340 Mucin-1/MUC1 Protein, Human, Recombinant Human HEK293
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPY-02005 Mucin-1/MUC1 Protein, Human, Recombinant (hFc) Human HEK293
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPJ-00376 IL-17RD Protein, Human, Recombinant (hFc) Human Human Cells
Interleukin-17 receptor D (IL-17 RD), also known as SEF (similar expression to FGFs), is a type I transmembrane protein that is found in both the cytoplasm and plasma membrane. IL-17RD functions as a feedback inhibitor o...
TMPH-01967 PADI3 Protein, Human, Recombinant (His) Human Yeast
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at...
TMPY-04425 PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated...
TMPY-04544 MEK2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/...
TMPH-01525 CMAHP Protein, Human, Recombinant (His & Myc) Human E. coli
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate...
TMPK-00136 ULBP-2 Protein, Human, Recombinant (His & Avi) Human HEK293
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, E...
TMPH-03037 Alpha-cobratoxin Protein, Naja kaouthia, Recombinant (GST & His & Myc) Naja kaouthia E. coli
Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes...
TMPK-00723 RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc) Mouse HEK293
TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPY-03675 TSPAN8 Protein, Human, Recombinant (mFc) Human HEK293
Tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional regulators, which affect TSPAN8 expression during melanoma progression toward an invasive stage. p53 as a nega...
TMPY-02127 DUSP3 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Vaccinia H1-related phosphatase (VHR) is classified as a dual-specificity phosphatase (DUSP), and the other name is dual-specificity phosphatase 3 (DUSP3). DUSPs are a heterogeneous group of protein phosphatases that can...
TMPY-03482 DUSP3 Protein, Human, Recombinant Human Baculovirus-Insect Cells
Vaccinia H1-related phosphatase (VHR) is classified as a dual-specificity phosphatase (DUSP), and the other name is dual-specificity phosphatase 3 (DUSP3). DUSPs are a heterogeneous group of protein phosphatases that can...
TMPK-00820 AREG Protein, Human, Recombinant (hFc) Human HEK293
Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic ca...
TMPK-00351 RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc) Human HEK293
TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPY-00338 IL-17RD Protein, Canine, Recombinant (hFc) Canine HEK293
Interleukin-17 receptor D (IL-17D) also known as Interleukin-17 receptor-like protein, is a member of the interleukine-17 receptor family. IL-17RD functions as a feedback inhibitor of fibroblast growth factor-mediated Ra...
TMPY-00625 IL-17RD Protein, Canine, Recombinant (His) Canine HEK293
Interleukin-17 receptor D (IL-17D) also known as Interleukin-17 receptor-like protein, is a member of the interleukine-17 receptor family. IL-17RD functions as a feedback inhibitor of fibroblast growth factor-mediated Ra...
TMPK-00926 Noggin/NOG Protein, Mouse, Recombinant (His & Flag) Mouse HEK293
Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer G...
TMPK-00925 Noggin/NOG Protein, Mouse, Recombinant Mouse HEK293
Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer G...
TMPH-01449 Human herpesvirus 2 (HHV-2) (strain HG52) Tegument protein VP22 (His) HHV-2 E. coli
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regula...
TMPY-00844 IL-17RD Protein, Human, Recombinant (His) Human HEK293
Interleukin-17 receptor D (IL-17D) also known as Interleukin-17 receptor-like protein, is a member of the interleukine-17 receptor family. IL-17RD functions as a feedback inhibitor of fibroblast growth factor-mediated Ra...
TMPY-04374 MST4 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
MST4, also known as mammalian STE2-like protein kinase 4, is a novel member of the germinal center kinase subfamily of human Ste2-like kinases and is closely related to MST3. The 416 amino acid full-length MST4 contains ...
TMPY-04378 MAPKAPK3 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
The MAPKAP kinases are a group of MAP kinase substrates that are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases ...
TMPK-01216 SEMA7A Protein, Mouse, Recombinant (His) Mouse HEK293
Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic ra...
TMPJ-01125 PEA15 Protein, Human, Recombinant Human E. coli
Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis...
TMPK-00741 SEMA7A Protein, Human, Recombinant (His) Human HEK293
Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic ra...
TMPY-02334 ULBP-2 Protein, Human, Recombinant (hFc) Human HEK293
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPH-00923 TTPA Protein, Human, Recombinant (His & SUMO) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis. Induces cartilage and bone formation. Initiates the canonical...
TMPJ-00796 Serpin E2 Protein, Human, Recombinant (His) Human Human Cells
Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal panc...
TMPH-02086 SRSF3 Protein, Human, Recombinant (GB1 & His) Human E. coli
Plays a pivotal role in manganese transport. Manganese is an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic p...
TMPY-02595 DUSP14 Protein, Human, Recombinant (His & MBP) Human E. coli
Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosph...
TMPY-04365 MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST) Human Baculovirus-Insect Cells
Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser ...
TMPY-04748 MKK6 Protein, Human, Recombinant Human Baculovirus-Insect Cells
Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser ...
TMPY-04466 STK40 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
STK40 is localized to both the cytoplasm and the nucleus. It is ubiquitously expressed. Mechanistically, Stk40 interacts with Rcn2, which also activates Erk1/2 to induce ExEn specification in mouse ESCs. Stk40 is able to...
TMPH-00926 MAOB Protein, Human, Recombinant (His) Human E. coli
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimu...
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ERK2 Protein, Human, Recombinant (GST)
TMPY-04539
Species: Human
Expression System: Baculovirus-Insect Cells
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
TMPY-04386
Species: Human
Expression System: Baculovirus-Insect Cells
EphB2 Protein, Human, Recombinant (His & hFc)
TMPY-00784
Species: Human
Expression System: HEK293
EphB2 Protein, Mouse, Recombinant (hFc)
TMPY-03621
Species: Mouse
Expression System: HEK293
EphB2 Protein, Human, Recombinant (His)
TMPY-01067
Species: Human
Expression System: HEK293
p38 gamma/MAPK12 Protein, Human, Recombinant
TMPY-04430
Species: Human
Expression System: Baculovirus-Insect Cells
p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)
TMPY-04429
Species: Human
Expression System: Baculovirus-Insect Cells
EphB2 Protein, Mouse, Recombinant (His)
TMPY-04216
Species: Mouse
Expression System: HEK293
ERK2 Protein, Mouse, Recombinant (His & GST)
TMPY-04571
Species: Mouse
Expression System: Baculovirus-Insect Cells
EPHB2 Protein, Cynomolgus, Recombinant (His)
TMPK-00563
Species: Cynomolgus
Expression System: HEK293
IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)
TMPJ-01464
Species: Human
Expression System: Human Cells
TSPAN8 Protein, Human, Recombinant (His)
TMPY-03564
Species: Human
Expression System: HEK293
MKK4 Protein, Mouse, Recombinant (His & GST)
TMPY-04572
Species: Mouse
Expression System: Baculovirus-Insect Cells
ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated
TMPY-05592
Species: Human
Expression System: HEK293
ULBP-2 Protein, Human, Recombinant (His)
TMPY-02333
Species: Human
Expression System: HEK293
Mucin-1/MUC1 Protein, Human, Recombinant
TMPY-04340
Species: Human
Expression System: HEK293
Mucin-1/MUC1 Protein, Human, Recombinant (hFc)
TMPY-02005
Species: Human
Expression System: HEK293
IL-17RD Protein, Human, Recombinant (hFc)
TMPJ-00376
Species: Human
Expression System: Human Cells
PADI3 Protein, Human, Recombinant (His)
TMPH-01967
Species: Human
Expression System: Yeast
PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)
TMPY-04425
Species: Human
Expression System: Baculovirus-Insect Cells
MEK2 Protein, Human, Recombinant (GST)
TMPY-04544
Species: Human
Expression System: Baculovirus-Insect Cells
CMAHP Protein, Human, Recombinant (His & Myc)
TMPH-01525
Species: Human
Expression System: E. coli
ULBP-2 Protein, Human, Recombinant (His & Avi)
TMPK-00136
Species: Human
Expression System: HEK293
Alpha-cobratoxin Protein, Naja kaouthia, Recombinant (GST & His & Myc)
TMPH-03037
Species: Naja kaouthia
Expression System: E. coli
RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)
TMPK-00723
Species: Mouse
Expression System: HEK293
TSPAN8 Protein, Human, Recombinant (mFc)
TMPY-03675
Species: Human
Expression System: HEK293
DUSP3 Protein, Human, Recombinant (His & GST)
TMPY-02127
Species: Human
Expression System: Baculovirus-Insect Cells
DUSP3 Protein, Human, Recombinant
TMPY-03482
Species: Human
Expression System: Baculovirus-Insect Cells
AREG Protein, Human, Recombinant (hFc)
TMPK-00820
Species: Human
Expression System: HEK293
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)
TMPK-00351
Species: Human
Expression System: HEK293
IL-17RD Protein, Canine, Recombinant (hFc)
TMPY-00338
Species: Canine
Expression System: HEK293
IL-17RD Protein, Canine, Recombinant (His)
TMPY-00625
Species: Canine
Expression System: HEK293
Noggin/NOG Protein, Mouse, Recombinant (His & Flag)
TMPK-00926
Species: Mouse
Expression System: HEK293
Noggin/NOG Protein, Mouse, Recombinant
TMPK-00925
Species: Mouse
Expression System: HEK293
Human herpesvirus 2 (HHV-2) (strain HG52) Tegument protein VP22 (His)
TMPH-01449
Species: HHV-2
Expression System: E. coli
IL-17RD Protein, Human, Recombinant (His)
TMPY-00844
Species: Human
Expression System: HEK293
MST4 Protein, Human, Recombinant (GST)
TMPY-04374
Species: Human
Expression System: Baculovirus-Insect Cells
MAPKAPK3 Protein, Human, Recombinant (GST)
TMPY-04378
Species: Human
Expression System: Baculovirus-Insect Cells
SEMA7A Protein, Mouse, Recombinant (His)
TMPK-01216
Species: Mouse
Expression System: HEK293
PEA15 Protein, Human, Recombinant
TMPJ-01125
Species: Human
Expression System: E. coli
SEMA7A Protein, Human, Recombinant (His)
TMPK-00741
Species: Human
Expression System: HEK293
ULBP-2 Protein, Human, Recombinant (hFc)
TMPY-02334
Species: Human
Expression System: HEK293
TTPA Protein, Human, Recombinant (His & SUMO)
TMPH-00923
Species: Human
Expression System: E. coli
Serpin E2 Protein, Human, Recombinant (His)
TMPJ-00796
Species: Human
Expression System: Human Cells
SRSF3 Protein, Human, Recombinant (GB1 & His)
TMPH-02086
Species: Human
Expression System: E. coli
DUSP14 Protein, Human, Recombinant (His & MBP)
TMPY-02595
Species: Human
Expression System: E. coli
MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)
TMPY-04365
Species: Human
Expression System: Baculovirus-Insect Cells
MKK6 Protein, Human, Recombinant
TMPY-04748
Species: Human
Expression System: Baculovirus-Insect Cells
STK40 Protein, Human, Recombinant (His & GST)
TMPY-04466
Species: Human
Expression System: Baculovirus-Insect Cells
MAOB Protein, Human, Recombinant (His)
TMPH-00926
Species: Human
Expression System: E. coli
Cat No. Product Name
L2192 Anti-Pancreatic Cancer Compound Library

2267 compounds
A unique collection of 2267 pancreatic cancer related compounds can be used in HTS and HCS;
TargetMol