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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling
MAPK Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
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Stem Cells Tyrosine Kinase/Adaptors Ubiquitination
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Search Result

Search Results for "human fibroblasts"

Compounds

Cat No. Product Name
T1684 Nitisinone NTBC,Nitisone,SC0735,尼替西农 Others , Reactive Oxygen Species
Nitisinone 是一种 4-羟基苯丙酮酸双加氧酶抑制剂。
T1889 CP-640186 CP 640186 Acetyl-CoA Carboxylase
CP 640186 是一种有效的乙酰辅酶 A 羧化酶 (ACC)抑制剂，抑制大鼠肝脏 ACC1 和大鼠骨骼肌 ACC2 的 IC50分别为 53 nM 和 61 nM。
T2437 O4I2 OCT
O4I2 是一种 Oct3/4诱导剂，可增强多能干细胞相关基因 Lin28、Sox2和 Nanog 的表达，并抑制 Rex1。
T36442L (Hyp³)-Bradykinin acetate Bradykinin Receptor
(Hyp³)-Bradykinin acetate 是一种缓激肽 B2 受体激动剂，可刺激培养的人成纤维细胞中磷酸肌醇的产生。
T21653 1,4-DPCA HIF/HIF Prolyl-Hydroxylase
1,4-DPCA 是一种脯氨酰羟化酶抑制剂，对人源包皮成纤维细胞中胶原羟基化的 IC50 为 2.4 μM，对因子抑制 HIF (FIH) 的 IC50 为 60 μM。
T4004 Concanavalin A Apoptosis
Concanavalin A 是 Ca2+/Mn2+依赖性和甘露糖/葡萄糖结合植物凝集素。它能够促使程序性细胞死亡。
T24706 RBC10 RBC-10,RBC 10 GTPase
RBC10 抑制 Ral 与其效应物 RALBP1 的结合，以及抑制 Ral 介导的鼠胚胎成纤维细胞的细胞扩散和人类癌细胞系的非贴壁依赖性生长。
T3768 Epifriedelanol 表木栓醇,Epifriedelinol Others
Epifriedelanol 是一种分离自 Ulmus davidiana 根皮中的三萜类化合物，具有抗肿瘤作用，可以减缓人原始细胞的衰老。
TN7117 Regaloside I Others
Regaloside I 是百合中的单体成分,可能是保护人类皮肤成纤维细胞免受 UVA 诱导的形态变化的主要成分。
T5120 Rhamnose 6-Deoxy-L-mannose,6-Deoxyhexopyranose,alpha-L-Rhamnose,L-鼠李糖 Endogenous Metabolite , Calcium Channel
alpha-L-Rhamnose 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞，能够作为肠吸收的标志。
T4100 AS8351 NSC51355,AS-8351,AS 8351 Histone Demethylase
AS8351 是一种组蛋白去甲基化酶抑制剂，可以诱导人胎儿肺成纤维细胞重编程为功能性心肌细胞。
T3622 CP-640186 hydrochloride CP 640186 HCl,盐酸CP-640186 Acetyl-CoA Carboxylase
CP-640186 hydrochloride 是膜渗透性的乙酰辅酶A 羧化酶（ACC）抑制剂，抑制大鼠肝脏ACC1和大鼠骨骼肌ACC2的IC50为53 nM 和61 nM。
T5295 1-Hydroxyoctadecane Octadecanol,1-Octadecanol,Stearyl alcohol,硬脂醇 Endogenous Metabolite , Others
1-Octadecanol 是内源性代谢产物的一种。
T5279 Ethylmalonic acid 2-Ethylmalonic acid,alpha-Carboxybutyrate,乙基丙二酸 Others , Endogenous Metabolite
Ethylmalonic acid 是潜在有毒物质，非致癌性，与神经性厌食和甲氧基脱羧酶缺乏症有关。
T2S2043 Dracorhodin perchlorate Dracohodin perochlorate,Dracorhodin perochlorate,血竭素高氯酸盐 Apoptosis , Others
Dracorhodin perochlorate 是来源于中药血竭的一种天然产物。它抑制细胞生长，并以剂量和时间依赖性方式诱导成纤维细胞凋亡，将细胞周期阻滞在 G1 期，可作为抗乳腺癌的候选药物。
T38293 4-CPPC Others
4-CPPC 是一种巨噬细胞迁移抑制因子 2 (MIF-2; IC50= 27 μM) 的抑制剂。它对 MIF-2 的选择性高于 MIF-1 (IC50= 450 μM)。 当以 10 μM 浓度使用时，它在体外抑制 MIF-2，但不抑制 ...
TP2341 Hexapeptide-11 Peptamide 6,Fvapfp,Phe-val-ala-pro-phe-pro
Hexapeptide-11 is a novel proteostasis network modulator in human diploid fibroblasts.
T4430 Isosaponarin Others
Isosaponarin increases collagen synthesis in human fibroblasts, causes by up-regulated TbetaR-II and P4H production.
T69502 HSP47 inhibitor III
HSP47 inhibitor III suppressed collagen type I expression in human and mouse cells and suppressed the viability and migr...
T30111 AR 12465 AR-12465
AR 12465 is a trapidil derivative which may affect LDL receptor mediated uptake and degradation of 125 I-LDL by human sk...
Nitisinone
T1684
synonym: NTBC,Nitisone,SC0735,尼替西农
Target:
CP-640186
T1889
synonym: CP 640186
Target:
O4I2
T2437
synonym:
Target:
(Hyp³)-Bradykinin acetate
T36442L
synonym:
Target:
1,4-DPCA
T21653
synonym:
Target:
Concanavalin A
T4004
synonym:
Target:
RBC10
T24706
synonym: RBC-10,RBC 10
Target:
Epifriedelanol
T3768
synonym: 表木栓醇,Epifriedelinol
Target:
regaloside I
TN7117
synonym:
Target:
Rhamnose
T5120
synonym: 6-Deoxy-L-mannose,6-Deoxyhexopyranose,alpha-L-Rhamnose,L-鼠李糖
Target:
AS8351
T4100
synonym: NSC51355,AS-8351,AS 8351
Target:
CP-640186 hydrochloride
T3622
synonym: CP 640186 HCl,盐酸CP-640186
Target:
1-Hydroxyoctadecane
T5295
synonym: Octadecanol,1-Octadecanol,Stearyl alcohol,硬脂醇
Target:
Ethylmalonic acid
T5279
synonym: 2-Ethylmalonic acid,alpha-Carboxybutyrate,乙基丙二酸
Target:
Dracorhodin perchlorate
T2S2043
synonym: Dracohodin perochlorate,Dracorhodin perochlorate,血竭素高氯酸盐
Target:
4-CPPC
T38293
synonym:
Target:
Hexapeptide-11
TP2341
synonym: Peptamide 6,Fvapfp,Phe-val-ala-pro-phe-pro
Target:
Isosaponarin
T4430
synonym:
Target:
HSP47 inhibitor III
T69502
synonym:
Target:
AR 12465
T30111
synonym: AR-12465
Target:
1 2 3 4 5
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