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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10876 | CPA inhibitor | Carboxypeptidase inhibitor | Carboxypeptidase |
CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM. | |||
T1804 | HPGDS inhibitor 1 | HPGDS-inhibitor-1 | PGE Synthase |
HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM. | |||
T5451 | Eph inhibitor 2 | Ehp-inhibitor-1 | Ephrin Receptor |
Eph inhibitor 2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. | |||
T2074 | Raf inhibitor 1 | B-Raf inhibitor 1 | Raf |
B-Raf inhibitor 1 (B-Raf inhibitor 1) is a potent and selective B-Raf inhibitor. | |||
T8766 | GOT1 inhibitor-1 | GOT1 inhibitor 2c | Others |
GOT1 inhibitor-1 (GOT1 inhibitor 2c) is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM. | |||
T38683 | SCD1 inhibitor-3 | SCD1-IN-3,SCD1 inhibitor-3,SCD1 inhibitor 17a | Dehydrogenase |
SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety. SCD1 inhibitor-3 demonstrates strong potential for research in metabolic diseases, including obesit... | |||
T4338 | USP7/USP47 inhibitor | USP7/47 inhibitor-1 | DUB |
USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM, respectively. | |||
T3042 | JAK2 Inhibitor V | JAK2 Inhibitor V Z3,Z3 | JAK |
JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner. | |||
T6335 | Tie2 kinase inhibitor 1 | Tie2 kinase inhibitor | Tie-2 |
Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38. | |||
T3593 | Src Inhibitor 1 | Src Kinase Inhibitor 1,Src-l1 | Src |
Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor. | |||
T5524 | Aurora kinase inhibitor-3 | Aurora Kinase Inhibitor III | Aurora Kinase |
Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR. | |||
T5817 | PKC-theta inhibitor hcl | PKC-theta inhibitor | PKC |
PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM). | |||
T67767 | HIF-1 inhibitor-4 | HIF-1 inhibitor-4 | HIF |
HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM. HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level. | |||
T3189 | B7/CD28 interaction inhibitor 1 | CTLA-4 inhibitor | Others |
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor. | |||
T4391 | Syk Inhibitor II dihydrochloride | Syk Inhibitor II (hydrochloride) | Others , Tyrosine Kinases , Syk , PKC , BTK |
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chains and mediates downstream signaling related to platelet fun... | |||
T2350 | MALT1 inhibitor MI-2 | MALT1 inhibitor,MI 2,MI 2 (MALT1 inhibitor) | MALT |
MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor. | |||
T7541 | PTP inhibitor 1 | PTP Inhibitor II | Phosphatase |
PTP inhibitor 1 is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)),with Ki of128 μM. | |||
T24141 | HIV-1 Inhibitor 18A | HIV-1 Inhibitor-18A | HIV Protease |
HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) specifically inhibits the entry of multiple HIV-1 isolates. | |||
T4167 | Raf inhibitor 1 dihydrochloride | B-Raf inhibitor 1 dihydrochloride | Raf |
Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) is a potent and selective B-Raf inhibitor. | |||
T4191 | Multi-kinase inhibitor 1 | Multi-kinase inhibitor I | Others , Bcr-Abl , PDGFR , c-Kit |
Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor. | |||
T10678 | Carboxypeptidase G2 (CPG2) Inhibitor | CPG2 Inhibitor,Carboxypeptidase G2 Inhibitor | Carboxypeptidase |
Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity. | |||
T2457 | IRAK-1-4 Inhibitor I | IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor | IRAK |
IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1. | |||
T17157 | TRAF-STOP inhibitor 6877002 | CD40-TRAF6 inhibitor | NF-κB |
TRAF-STOP inhibitor 6877002 (CD40-TRAF6 inhibitor), is a selective inhibitor of CD40-TRAF6 interaction. TRAF-STOP 6877002 reduces leukocyte recruitment, and reduces macrophage activation; reduces macrophage proliferation... | |||
T9178 | (E/Z)-GSK-3β inhibitor 1 | GSK-3β inhibitor 1 | GSK-3 |
(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy. | |||
T9040 | Aurora kinase inhibitor-2 | IUN-70219,Aurora Kinase Inhibitor II | Aurora Kinase |
Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M). | |||
T21954 | EGFR/ErbB-2/ErbB-4 inhibitor-2 | EGFR/ErbB2 Inhibitor | EGFR |
EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively) | |||
T36933 | Cdk2 Inhibitor II | Cdk2 Inhibitor II,CDK2-IN-3 | CDK |
Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM. | |||
T35827L | PKCε Inhibitor Peptide acetate | PKCε Inhibitor Peptide acetate(182683-50-7 Free base) | PKC |
PKCε Inhibitor Peptide acetate is a selective PKCε inhibitor containing the site for its specific receptor for activated C kinase (RACK). PKCε Inhibitor Peptide acetate inhibits the translocation of PKCε, but not α-, β-,... | |||
TP2008L | Lyn peptide inhibitor acetate | Lyn peptide inhibitor acetate(222018-18-0 free base) | IL Receptor |
Lyn peptide inhibitor acetate is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the bind... | |||
T22081 | FBPase-1 inhibitor-1 | Fructose 1,6-bisphosphatase-1 Inhibitor | Others |
FBPase-1 inhibitor-1 (Fructose 1,6-bisphosphatase-1 Inhibitor) is a fructose 1,6-bisphosphatase-1 inhibitor. | |||
T22136 | PRL-3 Inhibitor I | PRL-3 Inhibitor,BR-1 | Phosphatase , Others |
PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells. | |||
T10865L | Cot inhibitor-1 hydrochloride | Cot inhibitor-1 hydrochloride(915365-57-0 Free base) | TNF , MAPK |
Cot inhibitor-1 hydrochloride is an inhibitor of tumor progression loci-2 kinase (IC50 = 28 nM) and inhibits the production of TNF-α in human whole blood (IC50 = 5.7 nM). | |||
T4491 | LMPTP INHIBITOR 1 hydrochloride | LMPTP INHIBITOR 1 hydrochloride (1908414-82-3(free base)) | Phosphatase |
LMPTP INHIBITOR 1 hydrochloride is a selective inhibitor of low molecular weight protein tyrosine phosphatase ( LMPTP ), with an IC 50 of 0.8 μM for LMPTP-A. | |||
T2159 | CaMKP Inhibitor | CaMK | |
CaMKP Inhibitor can inhibit CaMKP. | |||
T10599 | BRAF inhibitor | Raf | |
BRAF inhibitor is an inhibitor of B-Raf. | |||
TP1015 | NFAT Inhibitor | VIVIT peptide | Others |
NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT. | |||
T10927 | Cyt-PTPε Inhibitor-1 | Cyt-PTP|A Inhibitor-1 | Phosphatase , Src |
Cyt-PTPε Inhibitor-1 (A Inhibitor-1) is an inhibitor of cytosolic protein tyrosine phosphatase ε. Cyt-PTPε Inhibitor-1 blocks the dephosphorylation of c-Src and exhibits anti-osteoclastic activity. | |||
TP1890L1 | MLCK inhibitor peptide 18 acetate | MLCK inhibitor peptide 18 acetate(224579-74-2 free base) | Serine/threonin kinase |
MLCK inhibitor peptide 18 acetate is a selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM). Displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. Cell permeable. | |||
TP1523 | PKG inhibitor peptide TFA (82801-73-8 free base) | PKG inhibitor peptide TFA | PKA |
PKG inhibitor peptide TFA (82801-73-8 free base) is an inhibitor of ATP-competitive cGMP-dependent protein kinase (PKG). | |||
T11184 | EML4-ALK kinase inhibitor 1 | EML4 ALK kinase inhibitor 1,EML4-ALK kinase inhibitor 1 | ALK |
EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM. | |||
T2649 | Menin-MLL inhibitor MI-2 | Menin-MLL Inhibitor,MI2,MI-2,Menin-MLL inhibitor 2,MI 2 | Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase |
Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM. | |||
T12502 | PLpro inhibitor | SARS-CoV | |
PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM) | |||
T21521L | Papain Inhibitor acetate | GGYR,Gly-Gly-Tyr-Arg,Papain Inhibitor acetate (70195-20-9 free base) | Others |
Papain Inhibitor acetate (Gly-Gly-Tyr-Arg) is an affinity Ligand for Papain. | |||
T60119 | SOD1-Derlin-1 inhibitor-1 | SOD1-Derlin-1 Inhibitor 56-20 | Others |
SOD1-Derlin-1 inhibitor-1 (SOD1-Derlin-1 Inhibitor 56-20) (compound 56-20) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-1 inhibits SOD1 G93A -Derlin-1 complex with an IC 50 value of 7.11 μM. SOD1... | |||
T10276L | AKT Kinase Inhibitor HCl | AKT Kinase Inhibitor HCl(842148-40-7 Free base) | Akt |
AKT Kinase Inhibitor HCl is an Akt inhibitor with antitumor activity. | |||
T22135 | PPIase-Parvulin Inhibitor | Others | |
PPIase-Parvulin Inhibitor is a cell-pemeable inhibitor of the Pin1 and Pin4. | |||
T11950 | MAT2A inhibitor 2 | Others , Methionine Adenosyltransferase (MAT) | |
MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A). | |||
T14124 | ADAMTS-5 Inhibitor | Others | |
ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 with an IC50 of 1.1 µM and can be used in studies about cartilage destruction in arthritis. | |||
T14913 | CD38 inhibitor 1 | CD38 | |
CD38 inhibitor 1 is an inhibitor of CD38. For hCD38 and mouse CD38, the IC50s are 7.3 nM and 1.9 nM. | |||
T4192 | Hnps-PLA Inhibitor | Phospholipase , LTR | |
Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3384 | Wedelolactone | IKK Inhibitor II | Apoptosis , NF-κB , Lipoxygenase , Caspase |
Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα. | |||
TJS0851 | Plantagoside | Others | |
Plantagoside is a specific non-competitive inhibitor for jack bean alpha-mannosidase (IC50: 5 μM). It also is a potent inhibitor of the Maillard reaction. | |||
TN1829 | Kakkalide | Dehydrogenase | |
Kakkalide is a potent lactate dehydrogenase (LDH) inhibitor, it has anti-inflammatory effects. | |||
TN3548 | Bulleyanin | Others | |
Bulleyanin shows strong inhibition of mouse ehrlich ascites carcinoma (ECA), mouse sarcoma S-180, and mouse liver ascites. | |||
T7032 | Eupatorin | Others , P450 | |
Eupatorin has antiproliferative and antiangiogenic effects. Eupatorin has antiproliferative and cytostatic effects on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism. Eupatorin-induced cell death is ... | |||
T13693 | Fibrin | Others | |
Fibrin, the primary constituent of blood clots, is an insoluble protein essential for coagulation. Isolated from bovine blood, this protein is notably synthesized in response to bleeding. | |||
TN1640 | Fabiatrin | Others | |
Fabiatrin is a natural product isolated and identified from n-butanol extract of Przewalskia tangutica. | |||
TWS1563 | Incensole | Others | |
1. Incensole has a protective or stimulating effect on β-cells of the rat pancreas, it also can increase the insulin secretion, which evidenced by a significant increase both in body weight and in liver glycogen. | |||
T8208 | Androsin | Others | |
Androsin, isolated from Picrorhiza Kurroa Royle ex Benth, has anti-asthmatic effects. | |||
T8169 | Decursinol | Others | |
Decursinol is isolated from the roots of Angelica Gigas with an antinociceptive effect. It also has anti-tumor and anti-metastasis activity. | |||
T3A2414 | Manninotriose | Others | |
Manninotriose has the pharmacological activities, such as promoting the proliferation of hematopoietic cells, improving immunity, lowering blood glucose and anti-tumor. | |||
T3928 | Neoliquiritin | Others | |
Neoliquiritin may possess ytotoxiciy and Tumor-specificity. | |||
T3817 | Darutigenol | Others | |
Darutigenol has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion. | |||
TN1028 | Militarine | Others | |
Militarine has plant inhibitory effect against the growth of Italian ryegrass, timothy, and B. striata. | |||
TN1453 | Bruceantinol | Anti-infection | |
Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng/mL. | |||
TQ0096 | Scabertopin | Others | |
Scabertopin is a sesquiterpene lactone isolated from Gentiana scabra with anticancer and bacteriostatic activities. | |||
T8203 | Gentianose | Others | |
Gentianose is a carbohydrate reserve derived from perennial yellow gentian storage roots. | |||
T7033 | Rosmanol | Antioxidant , COX | |
Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and a... | |||
T6S1049 | Wilforine | ATPase | |
Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be medi... | |||
T14291 | Anisindione | Others | |
Anisindione is a synthetic anticoagulant and an indanedione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibi... | |||
TN1982 | Neoglycyrol | Others | |
Neoglycyrol shows some cardioprotective effects . | |||
T3931 | Isobavachin | Others | |
Isobavachin can facilitate mouse ES cells differentiating into neuronal cells. | |||
T13350 | Wushanicaritin | Others | |
Wushanicaritin is a natural product isolated from the traditional Chinese medicine Epimedium plants, with antitumor effects and anti-inflammatory property. | |||
TN1002 | Blumeatin | ROS | |
Blumeatin has antioxidant properties, free radical scavenging activity,and has xanthine oxidase (XO) inhibitory activity. | |||
T19231 | Cellulase | Others | |
Cellulase is an enzyme that catalyzes the hydrolysis of certain linkages in cellulose. | |||
T39049 | Yubeinine | Others | |
Yubeinine is an alkaloid natural product possessing tracheal relaxant effects. | |||
T8194 | Isoflavone | Antioxidant | |
Isoflavones possess antioxidant properties and antipromotional effects. | |||
TN2058 | Persicogenin | Anti-infection | |
Persicogenin has anticancer, antimutagenic, and antileishmanial activities, it can inhibit the proliferation of mouse tsFT210 cancer cells, it mainly inhibits cell cycle at the G2/M phase in a dose-dependent manner. | |||
T8077 | Dihydrojasmone | Others | |
Dihydrojasmone is a natural product from bergamot | |||
TN1923 | Mesaconine | IL Receptor , NF-κB | |
Mesaconine is an ingredient from Aconitum carmichaelii Debx.. Mesaconine has a cardiac effect and anti-NF-κB activity. Mesaconine may be part of the material basis of Mahuang Fuzi Xixin decoction on anti-inflammation and... | |||
TN1983 | Neoisoastilbin | IL Receptor , TNF , NO Synthase | |
Neoisoastilbin may have antioxidant and anti-inflammatory activities. | |||
TN1800 | Isosakuranin | Others | |
Isosakuranin is a product from Paliurus ramosissimus. | |||
T3S1850 | Bayogenin | Others | |
Bayogenin is an alfalfa saponin, Bayogenin shows moderate potency of glycogen phosphorylase inhibition. | |||
TN1785 | Isomagnolone | Others | |
Isomagnolone is a natural product isolated from Illicium burmanicum and has anti-inflammatory activity. | |||
T19431 | Moluccanin | Others | |
Moluccanin is a natural product isolated from Aleurites moluccana. | |||
TN1075 | Adynerin | Others | |
Adynerin is a steroid found in the herbs of Nerium oleander. | |||
T8195 | Lotusine | Others | |
Lotusine is a pure alkaloid extracted from the Nelumbo nucifera Gaertn. It shows effects on the action potentials in the myocardium and slow inward current in cardiac Purkinje fibers. | |||
T8212 | Dichotomitin | Others | |
Dichotomitin is an natural isoflavonoid isolated from the rhizomes of Belamcanda chinensis (L.) DC. | |||
T6S2252 | Sweroside | Others | |
1. Sweroside possesses strong hepatoprotective effect. 2. Sweroside is a promising osteoporosis therapeutic natural product, has anti-osteoporotic effect on the human MG-63 cells and rat osteoblasts. | |||
T3S2027 | Rubusoside | Others | |
1. Rubusoside is a natural sweetener . 2. Rubusoside is a solubilizing agent with antiangiogenic and antiallergic properties. | |||
T6S0234 | Toosendanin | Others | |
1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. 3. Toosendanin i... | |||
T3S2019 | Lathyrol | Others | |
1.Lathyrol diterpenes is a modulator of P-glycoprotein dependent multidrug resistance. | |||
T5777 | Phaseoloidin | Others | |
Phaseoloidin, a homogentisic acid glucoside from Nicotiana attenuata trichomes, contributes to the plant's resistance against lepidopteran herbivores. | |||
T5S1331 | Herbacetin | c-Met/HGFR , Akt | |
1. Herbacetin induces apoptosis in HepG2 cells, by ROS and PI3K/Akt pathway. 2. Herbacetin suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation. | |||
TN2197 | Secoisolariciresinol | TNF | |
Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation in 3T3-L1 adipocytes. | |||
T6S0525 | Farrerol | ERK , p38 MAPK , Akt | |
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3.... | |||
T16943 | Stigmastanol | Endogenous Metabolite | |
Stigmastanol is a phytosterol. | |||
Fr13711 | Tropinone | Others | |
Tropinone used as an intermediate in the synthesis of atropine sulfate, and is a decane alkaloid. | |||
TN1065 | Hirsutine | Apoptosis | |
Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive and anti-arrhythmic activities, it also has vasodilatation acti... | |||
T10619 | Bromelain | Apoptosis , Others | |
Bromelain is an anti-inflammatory drug derived from pineapple stem. It acts through down-regulation of plasma kininogen, degradation of advanced glycation end-product receptors, inhibition of Prostaglandin E2 expression,... | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04815 | C1 inhibitor Protein, Rat, Recombinant (His) | Rat | HEK293 |
Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact s... | |||
TMPY-01183 | C1 inhibitor Protein, Human, Recombinant (His) | Human | HEK293 |
Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact s... | |||
TMPY-01030 | TFPI Protein, Human, Recombinant (His) | Human | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPY-01174 | DKK1 Protein, Rhesus, Recombinant (N256Q, His) | Rhesus | HEK293 |
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ... | |||
TMPY-04811 | DKK1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ... | |||
TMPY-01121 | DKK3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 p... | |||
TMPY-01474 | PAI-1 Protein, Human, Recombinant (His) | Human | HEK293 |
Plasminogen activator inhibitor 1, also known as PAI-1, Endothelial plasminogen activator inhibitor, SerpinE1 and PLANH1, is a secreted glycoprotein that belongs to the serpin family. SerpinE1 is the primary physiologica... | |||
TMPY-02731 | SPINK4 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-6 homolog and SPINK4, is a secreted protein that contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine... | |||
TMPY-06074 | B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express... | |||
TMPY-00775 | DKK1 Protein, Human, Recombinant (His) | Human | HEK293 |
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ... | |||
TMPH-00554 | Trypsin inhibitor DE-3 Protein, Erythrina caffra, Recombinant (His) | Erythrina caffra | Yeast |
Part of the tripartite complex that is required for the CDT activity. CdtC, along with CdtA, probably forms a heterodimeric subunit required for the delivery of CdtB. | |||
TMPY-05322 | B7-H4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express... | |||
TMPH-00520 | Host-nuclease inhibitor protein gam Protein, Enterobacteria phage lambda, Recombinant (His & Myc) | Escherichia phage lambda | E. coli |
Catalyzes the hydroxylation of 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | |||
TMPY-00915 | Serpin A1 Protein, Human, Recombinant (His) | Human | HEK293 |
SerpinA1, also known as Alpha-1 antitrypsin (AAT), is a prototype member of the Serpin superfamily of the serine protease inhibitors. This serine protease inhibitor blocks the protease, neutrophil elastase. Alpha-1 antit... | |||
TMPY-00916 | Antithrombin III Protein, Human, Recombinant (His) | Human | HEK293 |
SerpinC1, also known as antithrombin III (AT III), is a member of the serpin superfamily of serine protease inhibitors, and has been found to be a marker for disseminated intravascular coagulation (DIC) and to be of prog... | |||
TMPJ-00916 | TIMP-2 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Mouse Metalloproteinase inhibitor 2(TIMP-2), belongs to a family of proteins that regulate the activation and proteolytic activity of matrix metalloproteinases (MMPs). There are four mammalian members of the family; TIMP... | |||
TMPY-03524 | B7-H4 Protein, Human, Recombinant (His) | Human | HEK293 |
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express... | |||
TMPY-02912 | TIMP-1 Protein, Rat, Recombinant | Rat | HEK293 |
TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibi... | |||
TMPY-03876 | PTGFRN Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
EWI-F, also known as PTGFRN, is inversely related to the loss of CD9. Its expression correlates with the metastatic status of hLT. EWI-F inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP rece... | |||
TMPJ-00603 | TL1A Protein, Mouse, Recombinant | Mouse | E. coli |
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ... | |||
TMPJ-00490 | Serpin A5 Protein, Human, Recombinant (His) | Human | Human Cells |
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i... | |||
TMPJ-00733 | SPINK1 Protein, Human, Recombinant (His) | Human | Human Cells |
Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A dise... | |||
TMPJ-01289 | TIMP-4 Protein, Human, Recombinant (His) | Human | Human Cells |
Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreve... | |||
TMPY-00928 | TFPI Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPY-05800 | IKB beta/NFKBIB Protein, Human, Recombinant (GST) | Human | E. coli |
NFKBIB (NFKB Inhibitor Beta) is a Protein Coding gene. The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Phosphory... | |||
TMPY-00163 | SPINK2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Human serine proteinase inhibitor Kazal-type 2 (SPINK2) functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein ... | |||
TMPJ-00625 | Serpin E1 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. I... | |||
TMPJ-00101 | TIMP-2 Protein, Human, Recombinant (His) | Human | Human Cells |
Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the... | |||
TMPY-05179 | TFPI Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPJ-00972 | CDKN1B Protein, Human, Recombinant (His) | Human | E. coli |
Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skele... | |||
TMPY-05797 | DKK1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ... | |||
TMPJ-00931 | Serpin A4 Protein, Human, Recombinant (His) | Human | Human Cells |
Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and sec... | |||
TMPJ-01383 | Serpin A10 Protein, Human, Recombinant (His) | Human | Human Cells |
Serpin A10 is a secreted protein that belongs to the serpin family. It is predominantly expressed in the liver and secreted in the plasma. Its phosphorylation sites are present in the extracelllular medium. It inhibits f... | |||
TMPY-01175 | DKK1 Protein, Rhesus, Recombinant (N256Q, mFc) | Rhesus | HEK293 |
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ... | |||
TMPJ-01064 | Serpin G1 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement sy... | |||
TMPY-01456 | BAMBI Protein, Human, Recombinant (His) | Human | HEK293 |
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu... | |||
TMPY-04334 | BAMBI Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu... | |||
TMPY-02187 | SEMA5A Protein, Human, Recombinant (hFc) | Human | HEK293 |
Semaphorins are secreted, transmembrane, and GPI-linked proteins, defined by cysteine-rich semaphorin protein domains, that have important roles in a variety of tissues. Humans have 2 semaphorins, Drosophila has five, an... | |||
TMPY-01570 | SEMA5A Protein, Human, Recombinant (His) | Human | HEK293 |
Semaphorins are secreted, transmembrane, and GPI-linked proteins, defined by cysteine-rich semaphorin protein domains, that have important roles in a variety of tissues. Humans have 2 semaphorins, Drosophila has five, an... | |||
TMPJ-01069 | Serpin A1e Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-... | |||
TMPY-00933 | TIMP-2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Tissue inhibitors of metalloproteinases (TIMP) family are natural inhibitors of the matrix metalloproteinases (MMPs), the zinc enzymes involved in extracellular matrix maintenance and remodeling. The TIMP family encompas... | |||
TMPJ-00963 | CDKN2C Protein, Human, Recombinant (His) | Human | E. coli |
Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in... | |||
TMPY-00266 | PEDF Protein, Rat, Recombinant (His) | Rat | HEK293 |
Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glyco... | |||
TMPY-03127 | BAMBI Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu... | |||
TMPY-02981 | ING5 Protein, Human, Recombinant (GST) | Human | E. coli |
ING5 belongs to the ING family. It contains 1 PHD-type zinc finger and is a component of the HBO1 complex. HBO1 complex has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is re... | |||
TMPY-00629 | PAI-1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
Plasminogen activator inhibitor 1, also known as PAI-1, Endothelial plasminogen activator inhibitor, SerpinE1 and PLANH1, is a secreted glycoprotein that belongs to the serpin family. SerpinE1 is the primary physiologica... | |||
TMPJ-00452 | Serpin A1a Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Serpin A1a is also known as alpha-1-antitrypsin, is a member of the serpin superfamily of serine proteinase inhibitors that are involved in the regulation of a number of proteolytic processes. Its primary target is elast... | |||
TMPJ-00685 | BAI3 Protein, Human, Recombinant (His) | Human | Human Cells |
Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely... | |||
TMPJ-00243 | Serpin B6 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Serpin B6 belongs to the serpin family. Serpin B6 localizes to the cytoplasm. Serpin B6 is expressed in many tissues, abundantly by mast cells in different tissues and mastocytoma lesions. Serpin B6 may be involved in th... | |||
TMPY-00397 | ITIH3 Protein, Human, Recombinant (hFc) | Human | HEK293 |
ITIH3 (Inter-Alpha-Trypsin Inhibitor Heavy Chain 3) is a Protein Coding gene. This gene encodes the heavy chain subunit of the pre-alpha-trypsin inhibitor complex. This complex may stabilize the extracellular matrix thro... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L2000 | Inhibitor Library | 8418 compounds | |
A unique collection of 8418 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L9100 | Phosphatase Inhibitor Library | 80 compounds | |
A collection of 80 phosphatase inhibitors with known activity; | |||
L1100 | Protease Inhibitor Library | 344 compounds | |
A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening; | |||
L1400 | MAPK Inhibitor Library | 367 compounds | |
A unique collection of 367 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; | |||
L1600 | Kinase Inhibitor Library | 2230 compounds | |
A unique collection of 2230 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases; | |||
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; | |||
L3600 | Cytokine Inhibitor Library | 613 compounds | |
A unique collection of 613 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery; | |||
L9400 | PPI Inhibitor Library | 490 compounds | |
A unique collection of 490 PPI-related compounds for drug screening; | |||
L9410 | Covalent Inhibitor Library | 1949 compounds | |
A unique collection of 1949 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc. | |||
L2300 | Ion Channel Inhibitor Library | 946 compounds | |
A unique collection of 946 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery; | |||
L2200 | Tyrosine Kinase Inhibitor Library | 1033 compounds | |
A unique collection of 1033 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases; | |||
L1610 | FDA-Approved Kinase Inhibitor Library | 280 compounds | |
Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs with proven kinase inhibitory activity. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、... | |||
L2010 | Highly Selective Inhibitor Library | 580 compounds | |
A collection of xunm highly selective inhibitors | |||
L1510 | Nuclear Receptor Compound Library | 546 compounds | |
A unique collection of 546 nuclear receptor signaling targeted compounds for high throughput and high content screening; | |||
DO2200 | Covalent inhibitors Library | 12000 compounds | |
L8000 | Stem Cell Differentiation Compound Library | 1213 compounds | |
A unique collection of 1213 stem cell differentiation signaling targeted compounds for high throughput and high content screening; | |||
L7000 | Bioactive Lipid Compound Library | 385 compounds | |
A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, ... | |||
L7110 | Anti-Hypertension Compound Library | 719 compounds | |
719 hypertension-related small molecules for high-throughput and high-content screening. |