Search Result

Search Results for " jnk "

Compounds

Natural Products

114

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T7677	JNK Inhibitor VIII	TCS JNK 6o	JNK
	JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively).		JNK
T3598	JNK-IN-7	JNK inhibitor	JNK
	JNK-IN-7 (JNK inhibitor) is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM). It can also inhibit phosphorylation of c-Jun, which is a substrate of JNK kinase.		JNK
T2668	JNK-IN-8	JNK Inhibitor XVI	JNK , c-Kit
	JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRβ in A375 cell line.		JNK , c-Kit
T2234	TCS JNK 5a	SC202671,SC 202671,N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide,JNK Inhibitor IX,SC-202671	Apoptosis , JNK
	TCS JNK 5a (SC202671) is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).		Apoptosis , JNK
T38260	SP 600125, negative control	JNK Inhibitor II, negative control
	SP 600125, negative control is a methylated analog of SP 600125 and can be used as a negative control for SP 600125. SP 600125, negative control inhibits DTP3 and GADD45β/MKK7 (growth arrest and DNA damage-inducible β/me...
T3109	SP600125	1PMV,JNK Inhibitor II,Nsc75890,Pyrazolanthrone	Apoptosis , Ferroptosis , Trk receptor , JNK , Aurora Kinase , Autophagy
	SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis.
T60534	JNK-IN-11
	JNK-IN-11 (compound 1) is a potent inhibitor of JNK with the potential for Alzheimer's and Parkinson's disease research. JNK-IN-11 has IC50 values of 2.2, 21.4, 1.8 μM for JNK1, JNK2, JNK3, respectively.
T79754	JNK-IN-14		JNK
	JNK-IN-14 is a potent inhibitor of JNK with IC50 values of 1.81 nM for JNK1, 12.7 nM for JNK2, and 10.5 nM for JNK3. It induces early-stage apoptosis, arrests cell population at the G2/M phase, and moderately inhibits be...		JNK
T79296	JNK-IN-12		JNK
	JNK-IN-12 (compound P2) is a mitochondrial-targeted JNK inhibitor with an IC50 value of 66.3 nM, comprising a mitochondrial-specific cell-penetrating peptide linked to SP600125, a selective JNK inhibitor. It selectively ...		JNK
T79489	JNK-1-IN-2		JNK
	"JNK-1-IN-2 (Compound c6) is a potent inhibitor of JNK-1 with an IC50 of 33.5 nM, and also exhibits inhibitory effects on JNK-2 and JNK-3 with IC50 values of 112.9 nM and 33.2 nM, respectively. This compound effectively ...		JNK
T73109	JNK-1-IN-1
	JNK-1-IN-1 is an inhibitor specifically targeting JNK-1, also exhibiting inhibition of MKK7 with an IC50 value of 7.8μM. It binds to MKK7cp, further reinforcing its role as a JNK-1 inhibitor.
T62078	Akt/NF-κB/JNK-IN-1
	Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signalling pathways.Akt/NF-κB/JNK-IN-1 exhibits an inhibitory effect on nitric oxide production (IC50: 3.15 μM) and shows anti-inflammatory effects.
T61440	TOPK-p38/JNK-IN-1
	TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, with an IC50 value of 2.14 μM for the inhibition of NO production. It demonstrates anti-inflammatory properties by inh...
T3200	DB07268		JNK
	DB07268 is a potent and selective JNK1 inhibitor.		JNK
T6784	BI-78D3		JNK
	BI-78D3, a competitive JNK inhibitor. IC50 of BI-78D3 is 280 nM that displays > 100 fold selectivity over p38α, and have no activity at mTOR and PI-3K.		JNK
T16927	SR-3306		JNK
	SR-3306 is a potent and highly inhibitor of brain penetrant JNK.		JNK
T2675	Bentamapimod	AS 602801	JNK
	Bentamapimod (AS 602801) is a novel, orally active inhibitor of JNK.		JNK
T14895	Tanzisertib	CC-930	JNK
	Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.		JNK
T12189	NBDHEX		Apoptosis , Glutathione Peroxidase , Autophagy
	NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .		Apoptosis , Glutathione Peroxidase , Autophagy
T2035	WHI-P258		EGFR , JAK , JNK
	WHI-P258 is a dimethoxyquinazoline inhibitor of JAK3. This compound binds JAK3 weakly and may be used as a JAK-binding negative control in the development of new therapeutics.		EGFR , JAK , JNK
T8477	IQ-3		JNK
	IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α an...		JNK
T9688	CC-90001		JNK
	CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.		JNK
T2343	AS601245		JNK
	AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.		JNK
T5833	CC-401 Hydrochloride	CC401 HCl	JNK
	CC-401 Hydrochloride (CC401 HCl) is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor (Ki of 25 to 50 nM.)with potential antineoplastic activity.		JNK
T13018	SU3327	halicin	JNK
	SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).		JNK
T9010	IMM-H007		Others , AMPK
	IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression		Others , AMPK
T13099	TC ASK 10		ASK , MAPK
	TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1)(IC50 of 14 nM).		ASK , MAPK
T3627	IQ-1S free acid	IQ-1,IQ-1S,IQ-1S (free acid)	NF-κB , JNK
	IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can se...		NF-κB , JNK
T5097	Ezatiostat	TER199(free base),TLK199	Apoptosis , Glutathione Peroxidase , GST
	Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.		Apoptosis , Glutathione Peroxidase , GST
T6927	Pamapimod	R1503,Ro4402257	p38 MAPK , Autophagy
	Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectiv...		p38 MAPK , Autophagy
T9138	Indirubin-3′-oxime	Indirubin-3'-monoxime	GSK-3 , CDK , JNK
	Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.		GSK-3 , CDK , JNK
T0860	Mefloquine hydrochloride	Mefloquin hydrochloride,Mefloquine HCl	Potassium Channel , SARS-CoV , Reactive Oxygen Species , Parasite , Autophagy
	Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
T40248	JNK3 inhibitor-1	JNK3 inhibitor-1
	JNK3 inhibitor-1 is a highly potent and selective compound that specifically inhibits JNK3 with an impressive IC50 value of 0.005 μM. In addition to its remarkable inhibitory effects, JNK3 inhibitor-1 possesses excellent...
T0860L	Mefloquine	Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998	Others
	Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic l...		Others
T1606	Fasudil	HA-1077,AT877	ROCK , Serine/threonin kinase , Calcium Channel , PKA , PKC , Autophagy
	Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
T38665	OVA-E1 peptide TFA	OVA-E1 peptide TFA	p38 MAPK , JNK
	OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.		p38 MAPK , JNK
T3060	Fasudil hydrochloride	Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK , Serine/threonin kinase , Calcium Channel , HIV Protease , PKA , PKC , Autophagy
	Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
T22776	Ezatiostat hydrochloride	TLK199 HCl,TER199	Glutathione Peroxidase
	Ezatiostat hydrochloride (TLK199 HCl) is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatment of cytopenias. In addition, Ezatiostat hydr...		Glutathione Peroxidase
T10937L	D-JNKI-1 acetate	D-JNKI-1 acetate(1445179-97-4 Free base),AM-111 acetate	JNK
	D-JNKI-1 acetate (AM-111 acetate) is a highly potent and cell-permeable peptide inhibitor of JNK.		JNK
TP1353	L-JNKI-1
	L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK, it has been shown to effectively inhibit JNK activity in in vivo studies.
T74818	JNK3 inhibitor-8
	JNK3 Inhibitor-8 is a potent, selective, and orally active inhibitor that can cross the blood-brain barrier, targeting JNK3 with IC50 values of 21 nM for JNK3, 2203 nM for JNK2, and >10000 nM for JNK1. This compound demo...
T10937	D-JNKI-1	XG-102,AM-111	JNK
	D-JNKI-1 (AM-111) is a highly effective and cell-permeable peptide inhibitor.		JNK
T78829	JNK2-IN-1		JNK
	JNK2-IN-1 (Compound J27), a selective JNK2 inhibitor with a dissociation constant (Kd) of 79.2 µM, exhibits anti-inflammatory effects by attenuating TNF-α and IL-6 secretion via inhibition of the NF-κB/MAPK pathway. It e...		JNK
T60805	JNK3 inhibitor-2
	JNK3 inhibitor-2 is a potent and selective JNK3 inhibitor. The IC50 values of JNK3 inhibitor-2 for JNK1, JNK2, JNK3 are >100, >100, 0.25 μM, respectively. JNK3 inhibitor-2 also inhibits DDR1 and EGFR (T790M, L858R) [1].
T72715	JNK3 inhibitor-4
	JNK3 Inhibitor-4, a potent 2-aryl-1-pyrimidinyl-1H-imidazole-5-yl acetonitrile derivative, demonstrates a strong inhibitory effect on JNK3 with an IC 50 value of 1.0 nM. It exhibits exceptional selectivity against JNK3 w...
T74817	JNK3 inhibitor-7
	JNK3 inhibitor-7, a potent and orally active compound that can cross the blood-brain barrier, acts as a JNK3 inhibitor with IC50 values of 53 nM for JNK3, 973 nM for JNK2, and 1039 nM for JNK1. Demonstrating significant ...
T72714	JNK3 inhibitor-3		JNK
	JNK3 Inhibitor-3 (compound 15g) is a selective, blood-brain barrier permeable, and orally active inhibitor of c-Jun N-terminal kinase 3 (JNK3) with IC50 values of 147.8 nM, 44.0 nM, and 4.1 nM against JNK1, JNK2, and JNK...		JNK
TP1897L1	JIP-1 (153-163) acetate(438567-88-5 free base)		JNK
	JIP-1 (153-163) acetate is a peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1).		JNK
T5094	IRAK inhibitor 1		IRAK , JNK
	IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM).		IRAK , JNK
T24784	SF5	SF-5,SF 5	Apoptosis
	SF5 is an inhibitor of the apoptosis pathway. Which is through the JNK-p53-caspase apoptotic cascade.		Apoptosis

Compounds

JNK Inhibitor VIII

T7677

Synonym: TCS JNK 6o

Target: JNK

JNK-IN-7

T3598

Synonym: JNK inhibitor

Target: JNK

JNK-IN-8

T2668

Synonym: JNK Inhibitor XVI

Target: JNK, c-Kit

TCS JNK 5a

T2234

Synonym: SC202671,SC 202671,N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide,JNK Inhibitor IX,SC-202671

Target: Apoptosis, JNK

SP 600125, negative control

T38260

Synonym: JNK Inhibitor II, negative control

Target:

SP600125

T3109

Synonym: 1PMV,JNK Inhibitor II,Nsc75890,Pyrazolanthrone

Target: Apoptosis, Ferroptosis, Trk receptor, JNK, Aurora Kinase, Autophagy

Target: Apoptosis, Glutathione Peroxidase, Autophagy

WHI-P258

T2035

Synonym:

Target: EGFR, JAK, JNK

Synonym: IQ-1,IQ-1S,IQ-1S (free acid)

Target: NF-κB, JNK

Ezatiostat

T5097

Synonym: TER199(free base),TLK199

Target: Apoptosis, Glutathione Peroxidase, GST

Pamapimod

T6927

Synonym: R1503,Ro4402257

Target: p38 MAPK, Autophagy

Indirubin-3′-oxime

T9138

Synonym: Indirubin-3'-monoxime

Target: GSK-3, CDK, JNK

Mefloquine hydrochloride

T0860

Synonym: Mefloquin hydrochloride,Mefloquine HCl

Target: Potassium Channel, SARS-CoV, Reactive Oxygen Species, Parasite, Autophagy

JNK3 inhibitor-1

T40248

Synonym: JNK3 inhibitor-1

Target:

Mefloquine

T0860L

Synonym: Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998

Target: Others

Fasudil

T1606

Synonym: HA-1077,AT877

Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy

OVA-E1 peptide TFA

T38665

Synonym: OVA-E1 peptide TFA

Target: p38 MAPK, JNK

Fasudil hydrochloride

T3060

Synonym: Fasudil (HA-1077) HCl,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Ezatiostat hydrochloride

T22776

Synonym: TLK199 HCl,TER199

Target: Glutathione Peroxidase

D-JNKI-1 acetate

T10937L

Synonym: D-JNKI-1 acetate(1445179-97-4 Free base),AM-111 acetate

Synonym: XG-102,AM-111

JIP-1 (153-163) acetate(438567-88-5 free base)

Cat No.	Product Name	Synonyms	Targets
TQ0089	Juglanin		Apoptosis , JNK , Autophagy
	Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.		Apoptosis , JNK , Autophagy
T5S2283	Sesamolin		p38 MAPK , Caspase , JNK
	1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can s...		p38 MAPK , Caspase , JNK
T7190	Actein		Apoptosis , Akt , JNK , Autophagy
	Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in...		Apoptosis , Akt , JNK , Autophagy
T3S1641	Esculentoside H		TNF , NF-κB , JNK
	Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release.		TNF , NF-κB , JNK
TMA0507	Tomatidine		NF-κB , JNK , Autophagy
	Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways. Additionally, it induces autophagy in both mammalian cells and C. elegans.		NF-κB , JNK , Autophagy
TN3967	Epieriocalyxin A		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
	Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.		ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK
T3876	Loureirin B		PAI-1 , ERK , Potassium Channel , JNK
	Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathw...		PAI-1 , ERK , Potassium Channel , JNK
T5574	Guggulsterone	Guggulsterone E&Z	Apoptosis , FXR , Akt , Caspase , JNK , Autophagy
	Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.		Apoptosis , FXR , Akt , Caspase , JNK , Autophagy
T3895	Polyphyllin I		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
	Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
T6758	Anisomycin	Flagecidin,NSC 76712,Wuningmeisu C	Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK
	Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
T6S1371	Isovitexin	Homovitexin,Saponaretin,Apigenin-6-C-Glucoside	NF-κB , JNK , Glucosidase
	1. Isovitexin (Apigenin-6-C-Glucoside) exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits α-glucosidase in vivo.		NF-κB , JNK , Glucosidase
T2973	Astragaloside IV	AST-IV,AS-IV	MMP , ERK , Estrogen/progestogen Receptor , JNK
	Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cel...		MMP , ERK , Estrogen/progestogen Receptor , JNK
T4592	TOMATIDINE HYDROCHLORIDE	Tomatidine,Tomatidine HCl	Others , NF-κB , JNK , Autophagy
	Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine. Tomatid...		Others , NF-κB , JNK , Autophagy
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T2A2481	Taurochenodeoxycholic Acid	Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine	Apoptosis , TNF , Caspase , Endogenous Metabolite
	Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.		Apoptosis , TNF , Caspase , Endogenous Metabolite
T1205	Chloramphenicol	Chlornitromycin,Levomycetin,Chloromycetin	ribosome , HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Chloramphenicol (Chloromycetin), a broad-spectrum antibiotic, blocks bacterial protein synthesis.
TN2215	Taurochenodeoxycholic acid sodium	Sodium taurochenodeoxycholate	Apoptosis , Endogenous Metabolite
	Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...		Apoptosis , Endogenous Metabolite
T2872	Ginsenoside Re	Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re	Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
	Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.		Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
TN1879	Lucideric acid A	Lucidenic acid A	MMP , p38 MAPK , JNK
	Lucideric acid A (Lucidenic acid A) is a modulator of JNK and p38 and enhances LPS-induced immune responses in monocytic THP-1 cells possibly via the modulation of p38 and JNK/MAPKs activation.		MMP , p38 MAPK , JNK
T3755	Pinostilbene		Others
	Pinostilbene obviously attenuates the phosphorylation of c-Jun and JNK triggered by 6-OHDA.		Others
T10383	Asatone		NF-κB
	Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.		NF-κB
T3908	10-Gingerol		Apoptosis
	10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK).		Apoptosis
T3816	Velutin		NF-κB , HIF/HIF Prolyl-Hydroxylase
	Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK ...		NF-κB , HIF/HIF Prolyl-Hydroxylase
T3008	Lawsone methyl ether	2-Methoxy-1,4-naphthoquinone,2-Methoxy-p-naphthoquinone,2-Methoxynaphthoquinone	Apoptosis , Antibacterial , Antifungal
	Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone) induced apoptosis of A549 cells independent of cell cycle arrest, and is mediated by the JNK and p38 MAPK signaling pathways. Further analysis demonstrated that these s...		Apoptosis , Antibacterial , Antifungal
T3864	Erianin		BCL , Antibacterial
	Erianin is a nature product extracted from Dendrobium chrysotoxum, has notable antitumour activity , can cause extensive tumour necrosis, growth delay. Erianin has antiangiogenic action by inhibiting endothelial metaboli...		BCL , Antibacterial
TN2244	Sulfuretin		NF-κB , Autophagy
	Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr...		NF-κB , Autophagy
T5814	Aurantiamide	TMC-58B	p38 MAPK , NF-κB
	Aurantiamide has anti-cancer, anti-inflammatory and antinociceptive activities, it may suppress the growth of malignant gliomas by blocking autophagic flux.Aurantiamide has an anti-neuroinflammatory effect on LPS stimula...		p38 MAPK , NF-κB
T3676	Sesamol	1,3-Benzodioxol-5-ol,3,4-Methylenedioxyphenol	Apoptosis , AMPK
	Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 sig...		Apoptosis , AMPK
T4S1962	Beta-Asarone	Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin	NF-κB , JNK
	1. beta-Asarone (Cis-Isoelemicin) may be a potential preventive drug for Alzheimer's disease. 2. Beta-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in SAMP8 mice. 3. The co-administration of be...		NF-κB , JNK
T3S0737	Flavokawain A	Flavokavain A	Apoptosis , p38 MAPK
	NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant...		Apoptosis , p38 MAPK
TCS2170	2,5-Dihydroxyacetophenone	Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP	ERK , NF-κB , Tyrosinase
	1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...		ERK , NF-κB , Tyrosinase
TN1702	Glycycoumarin		P450 , JNK , AMPK , Autophagy
	Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.		P450 , JNK , AMPK , Autophagy
T4S1469	Cucurbitacin IIb		Apoptosis , Others
	1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i...		Apoptosis , Others
T2940	6-Hydroxyflavone	6-HF	GABA Receptor
	6-Hydroxyflavone (6-HF) is a noncompetitive inhibitors of cytochrome P450 2C9. It is a flavone, a type of chemical compound. It is reported in leaves of Barleria prionitis Linn. (a common Acanthaceae from India). 6-Hydro...		GABA Receptor
TL0004	FERULIC ACID METHYL ESTER	Methyl ferulate,Methyl 4'-hydroxy-3'-methoxycinnamate	p38 MAPK , Autophagy
	FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that p...		p38 MAPK , Autophagy
T3398	Icaritin	Anhydroicaritin,Cycloicaritin	Apoptosis , JAK , STAT , Autophagy
	Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Ica...		Apoptosis , JAK , STAT , Autophagy
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
TMA1004	Lucidenic acid F		p38 MAPK , JNK
	Lucidenic acid F as a modulator of JNK and p38, it shows potent inhibitory effects on EBV-EA induction.		p38 MAPK , JNK
T19960	Hinesol	(-)-Hinesol
	Hinesol is a unique sesquiterpenoid isolated from Atractylodes lancea rhizome. Hinesol has been found to induce apoptosis through the JNK signaling pathway in HL-60 cells.
TN4435	Licopyranocoumarin		P450 , ROS , JNK
	Licopyranocoumarin could as a potent neuroprotective drug via markedly blocked MPP+-induced neuronal PC12D cell death and disappearance of mitochondrial membrane potential, which were mediated by JNK.		P450 , ROS , JNK
TN1013	Cucurbitacin D		IL Receptor , JNK , STAT
	Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells.		IL Receptor , JNK , STAT
T80005	N-Butyl α-D-fructofuranoside		JNK
	N-Butyl α-D-fructofuranoside, extracted from the root barks of Ulmus davidiana var. japonica, amplifies Nrf2 activity via JNK activation and exhibits anti-inflammatory properties [1] [2].		JNK
T72236	Erythro-Austrobailignan-6
	Erythro-Austrobailignan-6, an orally active anti-cancer agent, inhibits DNA topoisomerase I and II activity, induces cell apoptosis, and enhances the phosphorylation of p38 and JNK.
TN2039	Panaxydol		cAMP , p38 MAPK , JNK
	Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 MAPK activation, cAMP, MAP kinase and ROS generation through ...		cAMP , p38 MAPK , JNK
TN4410	Lappaol C		P-gp , JNK
	Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidat...		P-gp , JNK
TN5387	Grasshopper ketone		ERK , p38 MAPK , NO Synthase , JNK
	Grasshopper ketone, isolated from the brown alga Sargassum, is a potent inhibitor of LPS-induced NO production in RAW 264.7 cells and induces anti-inflammatory effects by inhibiting MAPK (ERK, JNK and p38) and NF-κB p65 ...		ERK , p38 MAPK , NO Synthase , JNK
TN1072	Lappaol A		P-gp , JNK
	Lappaol A has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol A also has potential chemosensitizing activity, it may be candidat...		P-gp , JNK
TN4411	Lappaol F		CDK , P-gp , JNK
	1. Lappaol F has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. <br/> 2. Lappaol F has potential chemosensitizing activity, it may be c...		CDK , P-gp , JNK
TN5011	Shizukaol B		ERK , IL Receptor , p38 MAPK , TNF , NOS , NF-κB , COX , HIV Protease , DNA/RNA Synthesis , Prostaglandin Receptor , JNK
	Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinflammatory effects by inhibiting nitric-oxide (NO) production...
T37452	Stephacidin B
	Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, includ...
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Natural Products

Juglanin

TQ0089

Synonym:

Target: Apoptosis, JNK, Autophagy

Sesamolin

T5S2283

Synonym:

Target: p38 MAPK, Caspase, JNK

Actein

T7190

Synonym:

Target: Apoptosis, Akt, JNK, Autophagy

Esculentoside H

T3S1641

Synonym:

Target: TNF, NF-κB, JNK

Tomatidine

TMA0507

Synonym:

Target: NF-κB, JNK, Autophagy

Epieriocalyxin A

TN3967

Synonym:

Target: ERK, BCL, ROS, Caspase, DNA/RNA Synthesis, JNK

Loureirin B

T3876

Synonym:

Target: PAI-1, ERK, Potassium Channel, JNK

Guggulsterone

T5574

Synonym: Guggulsterone E&Z

Target: Apoptosis, FXR, Akt, Caspase, JNK, Autophagy

Polyphyllin I

T3895

Synonym:

Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy

Anisomycin

T6758

Synonym: Flagecidin,NSC 76712,Wuningmeisu C

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, JNK

Isovitexin

T6S1371

Synonym: Homovitexin,Saponaretin,Apigenin-6-C-Glucoside

Target: NF-κB, JNK, Glucosidase

Astragaloside IV

T2973

Synonym: AST-IV,AS-IV

Target: MMP, ERK, Estrogen/progestogen Receptor, JNK

TOMATIDINE HYDROCHLORIDE

T4592

Synonym: Tomatidine,Tomatidine HCl

Target: Others, NF-κB, JNK, Autophagy

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Taurochenodeoxycholic Acid

T2A2481

Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine

Target: Apoptosis, TNF, Caspase, Endogenous Metabolite

Chloramphenicol

T1205

Synonym: Chlornitromycin,Levomycetin,Chloromycetin

Target: ribosome, HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic

Taurochenodeoxycholic acid sodium

TN2215

Synonym: Sodium taurochenodeoxycholate

Target: Apoptosis, Endogenous Metabolite

Ginsenoside Re

T2872

Synonym: Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re

Target: Beta Amyloid, NF-κB, Endogenous Metabolite, JNK

Lucideric acid A

TN1879

Synonym: Lucidenic acid A

Target: MMP, p38 MAPK, JNK

Target: NF-κB, HIF/HIF Prolyl-Hydroxylase

Lawsone methyl ether

T3008

Synonym: 2-Methoxy-1,4-naphthoquinone,2-Methoxy-p-naphthoquinone,2-Methoxynaphthoquinone

Target: Apoptosis, Antibacterial, Antifungal

Erianin

T3864

Synonym:

Target: BCL, Antibacterial

Sulfuretin

TN2244

Synonym:

Target: NF-κB, Autophagy

Aurantiamide

T5814

Synonym: TMC-58B

Target: p38 MAPK, NF-κB

Sesamol

T3676

Synonym: 1,3-Benzodioxol-5-ol,3,4-Methylenedioxyphenol

Target: Apoptosis, AMPK

beta-Asarone

T4S1962

Synonym: Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin

Target: NF-κB, JNK

Flavokawain A

T3S0737

Synonym: Flavokavain A

Target: Apoptosis, p38 MAPK

2,5-Dihydroxyacetophenone

TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP

Target: ERK, NF-κB, Tyrosinase

Glycycoumarin

TN1702

Synonym:

Target: P450, JNK, AMPK, Autophagy

Cucurbitacin IIb

T4S1469

Synonym:

Target: Apoptosis, Others

6-Hydroxyflavone

T2940

Synonym: 6-HF

Target: GABA Receptor

FERULIC ACID METHYL ESTER

TL0004

Synonym: Methyl ferulate,Methyl 4'-hydroxy-3'-methoxycinnamate

Target: p38 MAPK, Autophagy

Icaritin

T3398

Synonym: Anhydroicaritin,Cycloicaritin

Target: Apoptosis, JAK, STAT, Autophagy

Mulberroside A

T6S1597

Synonym:

Target: TNF, Tyrosinase, Interleukin

Lucidenic acid F

TMA1004

Synonym:

Target: p38 MAPK, JNK

Target: P450, ROS, JNK

Cucurbitacin D

TN1013

Synonym:

Target: IL Receptor, JNK, STAT

n-Butyl α-D-fructofuranoside

T80005

Synonym:

Target: JNK

erythro-Austrobailignan-6

Target: cAMP, p38 MAPK, JNK

Target: ERK, p38 MAPK, NO Synthase, JNK

Target: CDK, P-gp, JNK

Shizukaol B

TN5011

Synonym:

Target: ERK, IL Receptor, p38 MAPK, TNF, NOS, NF-κB, COX, HIV Protease, DNA/RNA Synthesis, Prostaglandin Receptor, JNK

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04554	JNK1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellula...
TMPY-04550	JNK2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environm...
TMPK-01203	TNFRSF19 Protein, Human, Recombinant (hFc)	Human	HEK293
	A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for na...
TMPK-01204	TNFRSF19 Protein, Human, Recombinant (His)	Human	HEK293
	A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for na...
TMPY-03102	IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-01446	IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-02115	R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)	Human	HEK293
	R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in devel...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPY-05568	BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-03213	BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-04142	RANK/TNFRSF11A Protein, Human, Recombinant (hFc)	Human	HEK293
	TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-04493	BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-02028	RON/CD136 Protein, Human, Recombinant (His)	Human	HEK293
	The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. ...
TMPY-05319	BCMA/TNFRSF17 Protein, Human, Recombinant (His)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPK-00723	RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPK-00351	RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)	Human	HEK293
	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPH-01251	DUSP26 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis...
TMPH-02209	TRAF5 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation o...
TMPY-03655	GADD45G Protein, Human, Recombinant	Human	E. coli
	GADD45G, also known as CR6, is part of the nuclear proteins to interact with various proteins whose transcript levels are raised after stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45G re...
TMPY-04399	TAOK3 Protein, Human, Recombinant (aa 1-411, His & GST)	Human	Baculovirus-Insect Cells
	Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-9, CTCL-associated antigen HD-CL-9, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-i...
TMPH-01015	BMP-3 Protein, Human, Recombinant (His)	Human	E. coli
	Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of ce...
TMPY-06750	IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His)	Rabbit	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-00609	IL-18R beta/IL-18RAP Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-06312	IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-01388	TROY Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the duc...
TMPY-03103	IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-05792	TROY Protein, Mouse, Recombinant (mFc)	Mouse	HEK293
	Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the duc...
TMPJ-00344	IL-18RAP Protein, Human, Recombinant (hFc & His)	Human	Human Cells
	IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 a...
TMPY-03571	TROY Protein, Human, Recombinant (His)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the duc...
TMPY-06761	IL-18R beta/IL-18RAP Protein, Rat, Recombinant (His)	Rat	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-03194	TROY Protein, Human, Recombinant (hFc)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the duc...
TMPY-01200	IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-06316	IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-04916	RGMB Protein, Mouse, Recombinant (His)	Mouse	HEK293
	RGMB was knocked down in breast cancer cells by way of an anti-RGMB ribozyme transgene. Knockdown of RGMB resulted in enhanced capacities of proliferation, adhesion, and migration in breast cancer cells. Further investig...
TMPJ-01353	MBIPP Protein, Human, Recombinant (His)	Human	E. coli
	MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on ...
TMPJ-00700	GADD45B Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of g...
TMPJ-00711	GADD45G Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript...
TMPY-04906	RGMB Protein, Human, Recombinant (His)	Human	HEK293
	RGMB was knocked down in breast cancer cells by way of an anti-RGMB ribozyme transgene. Knockdown of RGMB resulted in enhanced capacities of proliferation, adhesion, and migration in breast cancer cells. Further investig...
TMPJ-00376	IL-17RD Protein, Human, Recombinant (hFc)	Human	Human Cells
	Interleukin-17 receptor D (IL-17 RD), also known as SEF (similar expression to FGFs), is a type I transmembrane protein that is found in both the cytoplasm and plasma membrane. IL-17RD functions as a feedback inhibitor o...
TMPJ-00358	DR6 Protein, Mouse, Recombinant (hFc & His)	Mouse	Human Cells
	Tumor necrosis factor receptor superfamily member 21(DR6) is a single-pass type I membrane protein and contains 1 death domain and 4 TNFR-Cys repeats. The protein may activate NF-kappa-B and promote apoptosis and it may ...
TMPH-02194	TAB2 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus
	Adapter required to activate the JNK and NF-kappa-B signaling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF). Acts as an adapter linking MAP3K7/TAK1...
TMPY-02191	BLNK Protein, Human, Recombinant (His)	Human	HEK293
	B-cell linker protein, also known as B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte p...
TMPJ-00397	IL-17RA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	CD217, also known as Interleukin-17 receptor A, is a T cell expressed pleotropic cytokine with 866 amino acids in length. CD217 functions as receptors for IL17A and IL17F, it binds to IL17A with higher affinity than to I...
TMPJ-00616	CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (His)	Rhesus macaque	Human Cells
	CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7，belongs to the TNF-receptor superfamily. CD27 is a single-p...
TMPY-02444	ATF2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-ac...
TMPJ-00615	CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (hFc)	Rhesus macaque	Human Cells
	CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7，belongs to the TNF-receptor superfamily. CD27 is a single-p...
TMPY-02127	DUSP3 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Vaccinia H1-related phosphatase (VHR) is classified as a dual-specificity phosphatase (DUSP), and the other name is dual-specificity phosphatase 3 (DUSP3). DUSPs are a heterogeneous group of protein phosphatases that can...
TMPY-02595	DUSP14 Protein, Human, Recombinant (His & MBP)	Human	E. coli
	Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosph...
TMPY-03482	DUSP3 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	Vaccinia H1-related phosphatase (VHR) is classified as a dual-specificity phosphatase (DUSP), and the other name is dual-specificity phosphatase 3 (DUSP3). DUSPs are a heterogeneous group of protein phosphatases that can...
TMPY-04109	Galectin-7 Protein, Human, Recombinant (His)	Human	E. coli
	LGALS7, also known as Galectin-7, is a member of the galectins family. The galectins are a family of beta-galactoside-binding proteins. There are at least 14 identified members of this family. Galectins share similaritie...
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JNK1 Protein, Human, Recombinant (GST)

TMPY-04554

Species: Human

Expression System: Baculovirus-Insect Cells

JNK2 Protein, Human, Recombinant (His)

TMPY-04550

Species: Human

Expression System: Baculovirus-Insect Cells

TNFRSF19 Protein, Human, Recombinant (hFc)

TMPK-01203

Species: Human

Expression System: HEK293

TNFRSF19 Protein, Human, Recombinant (His)

TMPK-01204

Species: Human

Expression System: HEK293

IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc)

TMPY-03102

Species: Rhesus

Expression System: HEK293

IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)

TMPY-01446

Species: Human

Expression System: HEK293

R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)

TMPY-02115

Species: Human

Expression System: HEK293

MKK4 Protein, Mouse, Recombinant (His & GST)

TMPY-04572

Species: Mouse

Expression System: Baculovirus-Insect Cells

BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated

TMPY-05568

Species: Human

Expression System: HEK293

BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc)

TMPY-03213

Species: Rhesus

Expression System: HEK293

RANK/TNFRSF11A Protein, Human, Recombinant (hFc)

TMPY-04142

Species: Human

Expression System: HEK293

BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)

TMPY-04493

Species: Human

Expression System: HEK293

RON/CD136 Protein, Human, Recombinant (His)

TMPY-02028

Species: Human

Expression System: HEK293

BCMA/TNFRSF17 Protein, Human, Recombinant (His)

TMPY-05319

Species: Human

Expression System: HEK293

RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)

TMPK-00723

Species: Mouse

Expression System: HEK293

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)

TMPK-00351

Species: Human

Expression System: HEK293

DUSP26 Protein, Human, Recombinant (His & SUMO)

TMPH-01251

Species: Human

Expression System: E. coli

TRAF5 Protein, Human, Recombinant (His & SUMO)

TMPH-02209

Species: Human

Expression System: E. coli

GADD45G Protein, Human, Recombinant

TMPY-03655

Species: Human

Expression System: E. coli

TAOK3 Protein, Human, Recombinant (aa 1-411, His & GST)

TMPY-04399

Species: Human

Expression System: Baculovirus-Insect Cells

BMP-3 Protein, Human, Recombinant (His)

TMPH-01015

Species: Human

Expression System: E. coli

IL-18R beta/IL-18RAP Protein, Rabbit, Recombinant (His)

TMPY-06750

Species: Rabbit

Expression System: HEK293

IL-18R beta/IL-18RAP Protein, Mouse, Recombinant (His)

TMPY-00609

Species: Mouse

Expression System: Baculovirus-Insect Cells

IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06312

Species: Human

Expression System: HEK293

TROY Protein, Mouse, Recombinant (His)

TMPY-01388

Species: Mouse

Expression System: HEK293

IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (His)

TMPY-03103

Species: Rhesus

Expression System: HEK293

TROY Protein, Mouse, Recombinant (mFc)

TMPY-05792

Species: Mouse

Expression System: HEK293

IL-18RAP Protein, Human, Recombinant (hFc & His)

TMPJ-00344

Species: Human

Expression System: Human Cells

TROY Protein, Human, Recombinant (His)

TMPY-03571

Species: Human

Expression System: HEK293

IL-18R beta/IL-18RAP Protein, Rat, Recombinant (His)

TMPY-06761

Species: Rat

Expression System: HEK293

TROY Protein, Human, Recombinant (hFc)

TMPY-03194

Species: Human

Expression System: HEK293

IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc)

TMPY-01200

Species: Human

Expression System: HEK293

IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPY-06316

Species: Human

Expression System: HEK293

RGMB Protein, Mouse, Recombinant (His)

TMPY-04916

Species: Mouse

Expression System: HEK293

MBIPP Protein, Human, Recombinant (His)

TMPJ-01353

Species: Human

Expression System: E. coli

GADD45B Protein, Human, Recombinant (His)

TMPJ-00700

Species: Human

Expression System: E. coli

GADD45G Protein, Human, Recombinant (His)

TMPJ-00711

Species: Human

Expression System: E. coli

RGMB Protein, Human, Recombinant (His)

TMPY-04906

Species: Human

Expression System: HEK293

IL-17RD Protein, Human, Recombinant (hFc)

TMPJ-00376

Species: Human

Expression System: Human Cells

DR6 Protein, Mouse, Recombinant (hFc & His)

TMPJ-00358

Species: Mouse

Expression System: Human Cells

TAB2 Protein, Human, Recombinant (His & Myc)

TMPH-02194

Species: Human

Expression System: Baculovirus

BLNK Protein, Human, Recombinant (His)

TMPY-02191

Species: Human

Expression System: HEK293

IL-17RA Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00397

Species: Human

Expression System: Human Cells

CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (His)

TMPJ-00616

Species: Rhesus macaque

Expression System: Human Cells

ATF2 Protein, Human, Recombinant (His & GST)

TMPY-02444

Species: Human

Expression System: Baculovirus-Insect Cells

CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (hFc)

TMPJ-00615

Species: Rhesus macaque

Expression System: Human Cells

DUSP3 Protein, Human, Recombinant (His & GST)

TMPY-02127

Species: Human

Expression System: Baculovirus-Insect Cells

DUSP14 Protein, Human, Recombinant (His & MBP)

TMPY-02595

Species: Human

Expression System: E. coli

DUSP3 Protein, Human, Recombinant

TMPY-03482

Species: Human

Expression System: Baculovirus-Insect Cells

Galectin-7 Protein, Human, Recombinant (His)

TMPY-04109

Species: Human

Expression System: E. coli

--------- More ---------

Cat No.	Product Name
L1610	FDA-Approved Kinase Inhibitor Library	266 compounds
	A unique collection of 266 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L1600	Kinase Inhibitor Library	2720 compounds
	A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;

Libraries

FDA-Approved Kinase Inhibitor Library

L1610

Compounds: 266

Kinase Inhibitor Library

L1600

Compounds: 2720