Home Tools
Log in
Cart

Search Result

Search Results for " mapk������������ "

224

Compounds

103

Natural Products

183

Recombinant Proteins

8

Libraries

Cat No. Product Name Synonyms Targets
T36010 P38 MAPK Inhibitor p38 MAPK
p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.
T38796L MBP MAPK Substrate acetate MBP MAPK Substrate acetate(138028-00-9 free base) MAPK
MBP MAPK Substrate acetate can be used as an exogenous substrate for MAPK.
T12347 P38-α MAPK-IN-1 p38 MAPK , Autophagy
p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor(IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay).
T38796 MBP MAPK Substrate
MBP MAPK Substrate is used as an exogenous substrate for MAPK.
T63119 NF-κB/MAPK-IN-1 NF-κB , MAPK
NF-κB/MAPK-IN-1 is a potent dual inhibitor of the NF-κB and MAPK pathways with potential anti-inflammatory activity, inhibition of NO production, and inhibition of LPS-induced activation of iNOS, COX-2, ERΚ and P38. NF-κ...
T35420 (S)-p38 MAPK Inhibitor III (S)-p38 MAPK Inhibitor III
(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is cell-permeable, potently blocking the release of TNF-α and IL-1β from human peripheral blood mononucle...
T16424 P38 MAPK-IN-1 p38 MAPK
p38 MAPK-IN-1 displays sustained levels, low clearance, and good bioavailability. p38 MAPK-IN-1 is a novel effective and selective inhibitor of p38 MAPK (IC50: 68 nM).
T11241 P38 MAPK-IN-2 Others
p38 MAPK-IN-2 is an inhibitor of p38 kinase.
T36011 P38 MAP Kinase Inhibitor IV p38 MAPK Inhibitor IV
p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 μM for p38α, p38β, p38x, and p38δ, respectively, in vitro.[1] It also inhibits LPS-induced TNF-α an...
T70638 P38-α MAPK-IN-5
p38-α MAPK-IN-5 is a potent p38α inhibitor with IC 50 s of 0.1 nM, 0.2 nM, 944 nM, 4100 nM for p38α , p38 β, p38γ , p38δ , respectively. p38-α MAPK-IN-5 has anti-inflammatory effect. p38-α MAPK-IN-5 has the potential for...
T9697 ASK1-IN-1 ASK
ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays.
T11943 MAPK13-IN-1 p38 MAPK
MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).
T22115 SM-7368 NF-κB
The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.
T60754 MAPK-IN-1
MAPK-IN-1 (Compound 2) is an inhibitor of MAPK signaling pathway with anti-neuroinflammatory and neuroprotective activity that can be used for the research of Alzheimer's disease. MAPK-IN-1 inhibits AChE with an IC 50 of...
T79572 MAPK-IN-2 EGFR
MAPK-IN-2 (compound 3h) is an efficacious MAPK inhibitor with antineoplastic properties that significantly hinders proliferation across various cancer cell lines. It demonstrates robust suppression of the MAPK pathway (E...
T7661 SD-169 SD 169 p38 MAPK
SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.
T2513 VX-702 p38 MAPK , Autophagy
VX-702 is a highly specific p38α MAPK inhibitor, 14-fold higher selectivity for the p38α than p38β. VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifical...
T1974 PH-797804 PH797804 p38 MAPK , Autophagy
PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.
T61803 P38 MAPK-IN-3
p38 MAPK-IN-3 (Compound 2c) is a potent inhibitor of p38α MAPK, displaying antitumor properties by promoting apoptosis and increasing reactive oxygen species (ROS) production [1].
T10277 AL 8697 p38 MAPK
AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases. AL 8697 has anti-inflammatory activity.
T6976 SB 239063 SB239063 p38 MAPK , Autophagy
SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.
T14381 AZD7624 AZD-7624 p38 MAPK , TNF
AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.
T7323 BCI-215 Phosphatase
BCI-215 causes selective cancer cell cytotoxicity in part through non-redox-mediated activation of MAPK signaling
T4645 TA-01 p38 MAPK , Casein Kinase , Autophagy
TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.
T6934 Pexmetinib ARRY-614 Tie-2 , p38 MAPK , Autophagy
Pexmetinib (ARRY-614) (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.
T4078 SB 242235 SB-242235,SB242235 p38 MAPK , Autophagy
SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.
TQ0079 GNE-495 MAPK
GNE-495 is a potent and specific MAP4K4 inhibitor (IC50: 3.7 nM).
T61091 P38-α MAPK-IN-4
p38-α MAPK-IN-4 (Compound 69) is a selective p38α MAPK inhibitor with an IC 50 of 1.5 μM. p38-α MAPK-IN-4 rapidly and strongly prevents the development of mechanical allodynia (MA) in vivo [1].
T7367 Acumapimod BCT-197 p38 MAPK , Autophagy
Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).
T6089 Neflamapimod VX-745 p38 MAPK , Autophagy
Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.
T8843 APS6-45 MAPK , Ras
APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.
T4011 NCB-0846 NCB 0846 MAPK , Wnt/beta-catenin
NCB-0846 is an orally active TNIK inhibitor (IC50: 21 nM).
T62359 TLR4/NF-κB/MAPK-IN-1
TLR4/NF-κB/MAPK-IN-1 is a new type of antineuroinflammatory agent by suppressing TLR4/NF-kB/MAPK pathways.
T16501 PF-3644022 p38 MAPK , Serine Protease , MAPK
PF-3644022 is an effective, selective, and ATP-competitive MAPKAPK2 (MK2) inhibitor (IC50: 5.2 nM and a Ki of 3 nM). PF-3644022 potently inhibits TNFα production and has an anti-inflammatory effect. PF-3644022 also inhib...
T2432 PD 169316 Virus Protease , p38 MAPK , Autophagy
PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.
T7953 BpV(HOpic) bpV (HOpic) PTEN
BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM).
T6130 Skepinone-L CBS3830 p38 MAPK , Autophagy
Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.
T12979 BI-3406 p38 MAPK , MAPK , Ras
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.
T5643 NG25 MAPK
NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 nM, respectively.
T11942 MAP4K4-IN-3 Compound 17 MAPK
MAP4K4-IN-3 (Compound 17) may be a viable target for antidiabetic agents, a serine/threonine protein kinase.
T78838 Akt/NF-κB/MAPK-IN-1 p38 MAPK
Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 of 7.70 μM and demonstrates low toxicity. This compound exerts anti-inflammatory effects by impeding the Akt/NF-κB a...
T5494 MW-150 MW01-18-150SRM p38 MAPK , Autophagy
MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.
T2367 SKF-86002 SKF86002 p38 MAPK , TNF
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).
T9470 HPK1-IN-7 MAPK
HPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM).
T11898 LXH254 Raf
LXH254 is a potent C-Raf and B-Raf inhibitor.
T50005 Sertaconazole Antifungal
Sertaconazole is a broad-spectrum antifungal.
T9196 IACS-13909 BBP-398 Phosphatase
IACS-13909 (BBP-398), a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway.
T15250 ETC-206 MNK
ETC-206 is a selective inhibitor of MNK1 and MNK2 (IC50s: 64 nM and 86 nM).
T4597 UM-164 UM164,DAS-DFGO-II p38 MAPK , Src , Autophagy
UM-164 (DAS-DFGO-II) is a highly potent inhibitor of c-Src with a Kd of 2.7 nM. UM-164 also potently inhibits p38α and p38β.
T5483 DMX-5804 DMX-5084 MAPK
DMX-5804 is a potent, selective MAP4K4 inhibitor, with an IC50 of 3 nM.DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice.

Compounds

p38 MAPK Inhibitor
T36010
Synonym:
Target: p38 MAPK
MBP MAPK Substrate acetate
T38796L
Synonym: MBP MAPK Substrate acetate(138028-00-9 free base)
Target: MAPK
p38-α MAPK-IN-1
T12347
Synonym:
Target: p38 MAPK, Autophagy
MBP MAPK Substrate
T38796
Synonym:
Target:
NF-κB/MAPK-IN-1
T63119
Synonym:
Target: NF-κB, MAPK
(S)-p38 MAPK Inhibitor III
T35420
Synonym: (S)-p38 MAPK Inhibitor III
Target:
p38 MAPK-IN-1
T16424
Synonym:
Target: p38 MAPK
p38 MAPK-IN-2
T11241
Synonym:
Target: Others
p38 MAP Kinase Inhibitor IV
T36011
Synonym: p38 MAPK Inhibitor IV
Target:
p38-α MAPK-IN-5
T70638
Synonym:
Target:
ASK1-IN-1
T9697
Synonym:
Target: ASK
MAPK13-IN-1
T11943
Synonym:
Target: p38 MAPK
SM-7368
T22115
Synonym:
Target: NF-κB
MAPK-IN-1
T60754
Synonym:
Target:
MAPK-IN-2
T79572
Synonym:
Target: EGFR
SD-169
T7661
Synonym: SD 169
Target: p38 MAPK
VX-702
T2513
Synonym:
Target: p38 MAPK, Autophagy
PH-797804
T1974
Synonym: PH797804
Target: p38 MAPK, Autophagy
p38 MAPK-IN-3
T61803
Synonym:
Target:
AL 8697
T10277
Synonym:
Target: p38 MAPK
SB 239063
T6976
Synonym: SB239063
Target: p38 MAPK, Autophagy
AZD7624
T14381
Synonym: AZD-7624
Target: p38 MAPK, TNF
BCI-215
T7323
Synonym:
Target: Phosphatase
TA-01
T4645
Synonym:
Target: p38 MAPK, Casein Kinase, Autophagy
Pexmetinib
T6934
Synonym: ARRY-614
Target: Tie-2, p38 MAPK, Autophagy
SB 242235
T4078
Synonym: SB-242235,SB242235
Target: p38 MAPK, Autophagy
GNE-495
TQ0079
Synonym:
Target: MAPK
p38-α MAPK-IN-4
T61091
Synonym:
Target:
Acumapimod
T7367
Synonym: BCT-197
Target: p38 MAPK, Autophagy
Neflamapimod
T6089
Synonym: VX-745
Target: p38 MAPK, Autophagy
APS6-45
T8843
Synonym:
Target: MAPK, Ras
NCB-0846
T4011
Synonym: NCB 0846
Target: MAPK, Wnt/beta-catenin
TLR4/NF-κB/MAPK-IN-1
T62359
Synonym:
Target:
PF-3644022
T16501
Synonym:
Target: p38 MAPK, Serine Protease, MAPK
PD 169316
T2432
Synonym:
Target: Virus Protease, p38 MAPK, Autophagy
BpV(HOpic)
T7953
Synonym: bpV (HOpic)
Target: PTEN
Skepinone-L
T6130
Synonym: CBS3830
Target: p38 MAPK, Autophagy
BI-3406
T12979
Synonym:
Target: p38 MAPK, MAPK, Ras
NG25
T5643
Synonym:
Target: MAPK
MAP4K4-IN-3
T11942
Synonym: Compound 17
Target: MAPK
Akt/NF-κB/MAPK-IN-1
T78838
Synonym:
Target: p38 MAPK
MW-150
T5494
Synonym: MW01-18-150SRM
Target: p38 MAPK, Autophagy
SKF-86002
T2367
Synonym: SKF86002
Target: p38 MAPK, TNF
HPK1-IN-7
T9470
Synonym:
Target: MAPK
LXH254
T11898
Synonym:
Target: Raf
Sertaconazole
T50005
Synonym:
Target: Antifungal
IACS-13909
T9196
Synonym: BBP-398
Target: Phosphatase
ETC-206
T15250
Synonym:
Target: MNK
UM-164
T4597
Synonym: UM164,DAS-DFGO-II
Target: p38 MAPK, Src, Autophagy
DMX-5804
T5483
Synonym: DMX-5084
Target: MAPK
1 2 3 4 5
Cat No. Product Name Synonyms Targets
TN1445 Bisabolangelone p38 MAPK , MAPK
Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.
T3400 Bakuchiol p38 MAPK , DNA/RNA Synthesis , Autophagy
Bakuchiol possesses anti-tumor,and anti-helmenthic properties. It has cytotoxic activity, mainly due to its DNA polymerase1 inhibiting activity. Bakuchiol has anti-bacterial activity against oral pathogens, has great pot...
T5S2283 Sesamolin p38 MAPK , Caspase , JNK
1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can s...
T3860 Isoliquiritin apioside MMP , p38 MAPK , NF-κB
Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresse...
T2565 Hesperetin Apoptosis , p38 MAPK , 5-HT Receptor , Autophagy , TGF-beta/Smad
Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside hesperidin, is the predominant flavonoid in lemons and oranges.
TN1721 Gypenoside L ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a...
TN1079 Deoxyelephantopin NF-κB
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling
T2885 Esculin Aesculin Antiviral , p38 MAPK , Antibacterial
Esculin (Aesculin) is a glucoside found in horse chestnuts.
T0539 Dihydrocaffeic acid Hydrocaffeic acid Antioxidant , p38 MAPK , Endogenous Metabolite
Dihydrocaffeic acid (Hydrocaffeic acid), a metabolite of chlorogenic acid, is a well-known anti-oxidant component, has anti-oxidative, anti-Alzheimer's, neuroprotective, arousal, and lipid-lowering effects.
TN2081 Maohuoside A MAPK
Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.
T6S1740 Nardosinone Others
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed t...
T7051 5,6,7-TRIMETHOXYFLAVONE Baicalein Trimethyl Ether p38 MAPK
5,6,7-TRIMETHOXYFLAVONE is a natural product for research related to life sciences. The catalog number is T7051 and the CAS number is 973-67-1.
T5S2358 Dehydrocorydaline Dehydrocorydalin,13-Methylpalmatine BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...
T5S0761 Nitidine chloride Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T5S0089 Kaempferol-3-O-glucorhamnoside Kaempferol 3-glucorhamnoside Antioxidant , p38 MAPK , NF-κB
Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPK and NF-κB pathways in vitro and in vivo[1]. Kaempferol-3-O-gl...
T2S2362 Dehydrocorydaline nitrate BCL , Others , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a...
T4S2326 Cornuside 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside ERK , p38 MAPK , NF-κB , JNK
1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardi...
T10990 Dehydrocorydaline chloride 13-Methylpalmatine chloride BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.
T6427 Butein 2’,3,4,4’-tetrahydroxy Chalcone Apoptosis , EGFR , Others , PDE , Autophagy
Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.
TL0004 FERULIC ACID METHYL ESTER Methyl ferulate,Methyl 4'-hydroxy-3'-methoxycinnamate p38 MAPK , Autophagy
FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that p...
TL0006 Cichoric Acid Dicaffeoyltartaric acid,Chicoric Acid Reactive Oxygen Species , HIV Protease
Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ...
T9218 Andrograpanin 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE p38 MAPK
Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.
TN1968 N-​Feruloyloctopamine N-Feruloyloctopamine p38 MAPK , Akt
N-Feruloyloctopamine is a natural product.
T5281 Skatole Scatole,3-Methylindole,3-​Methylindole,3-Methyl-1H-indole,beta-Methylindole AhR , p38 MAPK , Aryl Hydrocarbon Receptor , Endogenous Metabolite , Antibacterial , Autophagy , Antifungal
Skatole (3-Methyl-1H-indole) is produced by intestinal bacteria. Skatole regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
T5429 Theaflavin 3,3'-digallate 8-Gingerol,TFDG Virus Protease , Antioxidant , HIV Protease , HSV
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...
T2755 Rhoifolin Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
T4085 Paris saponin VII Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
T5S0506 Rotundic acid Rutundic acid Apoptosis , Others , p38 MAPK , Akt , mTOR
Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) c...
TN4114 Gardenin A ERK , LDL , MAPK , PKA , PKC
Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects.
T10383 Asatone NF-κB
Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.
T5S1000 Sophoraflavanone G Kushenol F,Vexibinol Apoptosis
Sophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways.
T5729 L-quebrachitol Wnt/beta-catenin
L-quebrachitol is a natural product.L-quebrachitol may promote osteoblastogenesis by triggering the BMP-2-response as well as the Runx2, MAPK, and Wnt/β-catenin signaling pathway.
T2789 Scutellarin Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide Akt , HIV Protease , STAT
Scutellarin (Scutellarein-7-glucuronide), an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regulate the STAT3/Girdin/Akt signal...
T3896 Shanzhiside methyl ester Glucagon Receptor
Shanzhiside methylester reduces neuropathic pain by activating spinal GLP-1 receptors and subsequently stimulating microglial β-endorphin expression via the p38 MAPK signaling.
T3856 Tenuifoliside A ERK , Others
Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which is mediated by the inhibition of the NF-κB and MAPK pathways.
T16324 Nimbolide Apoptosis , NF-κB , CDK
Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene ...
T5716 4'-Methoxyresveratrol 4'-O-Methylresveratrol advanced glycation end products
4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a natural product form the roots of Rheum palmatum L,has significant hypoglycemic, anti-inflammatory, and antioxidant effects.4'-Methoxyresveratrol alleviates AGE-induced...
T4912 Jatrorrhizine chloride Yatrorhizine chloride,Neprotine chloride Others , 5-HT Receptor , OCT , Antibacterial , AChE
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h...
T3908 10-Gingerol 10-姜酚,[10]-姜酚 Apoptosis
10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK).
T3924 Astragaloside II Astrasieversianin VIII TGF-beta/Smad
Astragaloside II (Astrasieversianin VIII) is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Astragaloside II also induces osteogenic activities, differentiation, ...
T2S2382 3'-Hydroxypterostilbene 3'-HPT Apoptosis , Autophagy
3'-Hydroxypterostilbene (3'-HPT), a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, b...
T3008 Lawsone methyl ether 2-Methoxy-1,4-naphthoquinone,2-Methoxy-p-naphthoquinone,2-Methoxynaphthoquinone Apoptosis , Antibacterial , Antifungal
Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone) induced apoptosis of A549 cells independent of cell cycle arrest, and is mediated by the JNK and p38 MAPK signaling pathways. Further analysis demonstrated that these s...
T6S0095 Genkwanin 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether Virus Protease
1. Genkwanin (Apigenin 7-methyl ether) exerts its anti-inflammatory effect mainly through the regulation of the miR-11/MKP-1/MAPK pathway. 2. Genkwanin is transported by both passive diffusion and multidrug resistance pr...
T3410 Momordin Ic Momordin 1c Apoptosis , MAPK , PI3K
Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. A...
T3847 Asperuloside Asperulosid Others , NO Synthase
Asperuloside (Asperulosid) has anti-inflammatory activity.
T3836 Eudesmin MAPK , S6 Kinase
Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 m...
TN1410 Asperulosidic acid ASPA ERK , NF-κB
Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-a...
TN1936 Mogroside III-E IL Receptor , TNF , TLR
Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, has anti-inflammatory activity, it attenuates LPS-induced acute lung injury in mice partly through regulation of the TLR4/MAPK/NF-κB axis...
T5S1058 Triptonide PG 492,NSC 165677 Apoptosis , Wnt/beta-catenin , Autophagy
1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, an...
T3763 Fumaric acid Lichenic acid,Fumarate,2-Butenedioic acid,Trans-Butenedioic acid,Donitic acid,Allomaleic acid Endogenous Metabolite
Fumaric acid (2-Butenedioic acid) attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-κB signaling. Fumaric acid has recently been identified as an oncometabolite or a...
------------------------ More ------------------------

Natural Products

Bisabolangelone
TN1445
Synonym:
Target: p38 MAPK, MAPK
Bakuchiol
T3400
Synonym:
Target: p38 MAPK, DNA/RNA Synthesis, Autophagy
Sesamolin
T5S2283
Synonym:
Target: p38 MAPK, Caspase, JNK
Isoliquiritin apioside
T3860
Synonym:
Target: MMP, p38 MAPK, NF-κB
Hesperetin
T2565
Synonym:
Target: Apoptosis, p38 MAPK, 5-HT Receptor, Autophagy, TGF-beta/Smad
Gypenoside L
TN1721
Synonym:
Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS
Deoxyelephantopin
TN1079
Synonym:
Target: NF-κB
Esculin
T2885
Synonym: Aesculin
Target: Antiviral, p38 MAPK, Antibacterial
Dihydrocaffeic acid
T0539
Synonym: Hydrocaffeic acid
Target: Antioxidant, p38 MAPK, Endogenous Metabolite
Maohuoside A
TN2081
Synonym:
Target: MAPK
Nardosinone
T6S1740
Synonym:
Target: Others
5,6,7-TRIMETHOXYFLAVONE
T7051
Synonym: Baicalein Trimethyl Ether
Target: p38 MAPK
Dehydrocorydaline
T5S2358
Synonym: Dehydrocorydalin,13-Methylpalmatine
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Nitidine chloride
T5S0761
Synonym:
Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite
Kaempferol-3-O-glucorhamnoside
T5S0089
Synonym: Kaempferol 3-glucorhamnoside
Target: Antioxidant, p38 MAPK, NF-κB
Dehydrocorydaline nitrate
T2S2362
Synonym:
Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Cornuside
T4S2326
Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside
Target: ERK, p38 MAPK, NF-κB, JNK
Dehydrocorydaline chloride
T10990
Synonym: 13-Methylpalmatine chloride
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Butein
T6427
Synonym: 2’,3,4,4’-tetrahydroxy Chalcone
Target: Apoptosis, EGFR, Others, PDE, Autophagy
FERULIC ACID METHYL ESTER
TL0004
Synonym: Methyl ferulate,Methyl 4'-hydroxy-3'-methoxycinnamate
Target: p38 MAPK, Autophagy
Cichoric Acid
TL0006
Synonym: Dicaffeoyltartaric acid,Chicoric Acid
Target: Reactive Oxygen Species, HIV Protease
Andrograpanin
T9218
Synonym: 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE
Target: p38 MAPK
N-​Feruloyloctopamine
TN1968
Synonym: N-Feruloyloctopamine
Target: p38 MAPK, Akt
Skatole
T5281
Synonym: Scatole,3-Methylindole,3-​Methylindole,3-Methyl-1H-indole,beta-Methylindole
Target: AhR, p38 MAPK, Aryl Hydrocarbon Receptor, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal
Theaflavin 3,3'-digallate
T5429
Synonym: 8-Gingerol,TFDG
Target: Virus Protease, Antioxidant, HIV Protease, HSV
Rhoifolin
T2755
Synonym: Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
Paris saponin VII
T4085
Synonym: Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII
Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy
Rotundic acid
T5S0506
Synonym: Rutundic acid
Target: Apoptosis, Others, p38 MAPK, Akt, mTOR
Gardenin A
TN4114
Synonym:
Target: ERK, LDL, MAPK, PKA, PKC
Asatone
T10383
Synonym:
Target: NF-κB
Sophoraflavanone G
T5S1000
Synonym: Kushenol F,Vexibinol
Target: Apoptosis
L-quebrachitol
T5729
Synonym:
Target: Wnt/beta-catenin
Scutellarin
T2789
Synonym: Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide
Target: Akt, HIV Protease, STAT
Shanzhiside methyl ester
T3896
Synonym:
Target: Glucagon Receptor
Tenuifoliside A
T3856
Synonym:
Target: ERK, Others
Nimbolide
T16324
Synonym:
Target: Apoptosis, NF-κB, CDK
4'-Methoxyresveratrol
T5716
Synonym: 4'-O-Methylresveratrol
Target: advanced glycation end products
Jatrorrhizine chloride
T4912
Synonym: Yatrorhizine chloride,Neprotine chloride
Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE
10-Gingerol
T3908
Synonym: 10-姜酚,[10]-姜酚
Target: Apoptosis
Astragaloside II
T3924
Synonym: Astrasieversianin VIII
Target: TGF-beta/Smad
3'-Hydroxypterostilbene
T2S2382
Synonym: 3'-HPT
Target: Apoptosis, Autophagy
Lawsone methyl ether
T3008
Synonym: 2-Methoxy-1,4-naphthoquinone,2-Methoxy-p-naphthoquinone,2-Methoxynaphthoquinone
Target: Apoptosis, Antibacterial, Antifungal
Genkwanin
T6S0095
Synonym: 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether
Target: Virus Protease
Momordin Ic
T3410
Synonym: Momordin 1c
Target: Apoptosis, MAPK, PI3K
Asperuloside
T3847
Synonym: Asperulosid
Target: Others, NO Synthase
Eudesmin
T3836
Synonym:
Target: MAPK, S6 Kinase
Asperulosidic acid
TN1410
Synonym: ASPA
Target: ERK, NF-κB
Mogroside III-E
TN1936
Synonym:
Target: IL Receptor, TNF, TLR
Triptonide
T5S1058
Synonym: PG 492,NSC 165677
Target: Apoptosis, Wnt/beta-catenin, Autophagy
Fumaric acid
T3763
Synonym: Lichenic acid,Fumarate,2-Butenedioic acid,Trans-Butenedioic acid,Donitic acid,Allomaleic acid
Target: Endogenous Metabolite

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04551 P38 delta/MAPK13 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
The p38 family of mitogen-activated protein kinases (MAPK) includes p38 alpha (SAPK2a, CSBP), p38 beta (SAPK2b), p38 delta (SAPK4), and p38 gamma (SAPK3/ERK6). p38 alpha and p38 beta are widely expressed p38 isoforms tha...
TMPY-04531 P38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro Human Baculovirus-Insect Cells
The p38 family of mitogen-activated protein kinases (MAPK) includes p38 alpha (SAPK2a, CSBP), p38 beta (SAPK2b), p38 delta (SAPK4), and p38 gamma (SAPK3/ERK6). p38 alpha and p38 beta are widely expressed p38 isoforms tha...
TMPY-04539 ERK2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, diffe...
TMPJ-01353 MBIPP Protein, Human, Recombinant (His) Human E. coli
MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on ...
TMPY-02252 LAMTOR2 Protein, Human, Recombinant (His) Human E. coli
Ragulator complex protein LAMTOR2, also known as Endosomal adaptor protein p14, Late endosomal/lysosomal Mp1-interacting protein, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2, Mitogen-activated protein-...
TMPY-04571 ERK2 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, diffe...
TMPY-04430 P38 gamma/MAPK12 Protein, Human, Recombinant Human Baculovirus-Insect Cells
ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/t...
TMPY-04429 P38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/t...
TMPJ-01378 Mp1 Protein, Human, Recombinant (His) Human E. coli
Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding pro...
TMPJ-00021 LGALS1 Protein, Human, Recombinant (His) Human E. coli
Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domain...
TMPY-00751 TrkB Protein, Human, Recombinant (His) Human HEK293
TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptor with intracellular tyrosine kin...
TMPY-02231 TrkB Protein, Mouse, Recombinant (His) Mouse HEK293
TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptor with intracellular tyrosine kin...
TMPY-05176 AMH Protein, Human, Recombinant (His) Human HEK293
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and ...
TMPY-02676 EGFR Protein, Mouse, Recombinant (His) Mouse HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-04818 EGFR Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-04529 EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) Human Baculovirus-Insect Cells
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-00742 EGFR Protein, Human, Recombinant (His) Human HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPJ-00662 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli) Human E. coli
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i...
TMPY-00665 Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) Human HEK293
Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 fam...
TMPY-03564 TSPAN8 Protein, Human, Recombinant (His) Human HEK293
Tetraspanin 8 (TSPAN8) as an important modulator of melanoma invasiveness, and several of its transcriptional regulators, which affect TSPAN8 expression during melanoma progression toward an invasive stage. p53 as a nega...
TMPY-03532 LIF Protein, Human, Recombinant (His) Human HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-04572 MKK4 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPY-04278 LIF Protein, Mouse, Recombinant Mouse HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-04104 LIF Protein, Human, Recombinant Human HEK293
Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-03577 Pleiotrophin/PTN Protein, Mouse, Recombinant Mouse Baculovirus-Insect Cells
HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, ...
TMPY-04976 PDGFC Protein, Mouse, Recombinant (His) Mouse Yeast
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-01053 Prolactin Receptor Protein, Human, Recombinant (His) Human HEK293
Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept...
TMPY-02879 IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158) Human E. coli
Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a...
TMPY-01084 TrkA Protein, Human, Recombinant (His) Human HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-01725 Leptin Receptor Protein, Human, Recombinant (His) Human HEK293
Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-spe...
TMPY-04340 Mucin-1/MUC1 Protein, Human, Recombinant Human HEK293
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPY-01167 E-Selectin/CD62E Protein, Human, Recombinant (His) Human HEK293
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involv...
TMPY-02005 Mucin-1/MUC1 Protein, Human, Recombinant (hFc) Human HEK293
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr...
TMPY-05090 CD25/IL2R alpha Protein, Rat, Recombinant (His) Rat Baculovirus-Insect Cells
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-01103 CD25/IL2R alpha Protein, Human, Recombinant (His) Human HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05584 CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-03644 CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-03776 CD25/IL2R alpha Protein, Cynomolgus, Recombinant Cynomolgus HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05644 CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated Rhesus HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-01923 CD25/IL2R alpha Protein, Mouse, Recombinant (His) Mouse HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-02551 CCDC134 Protein, Human, Recombinant (His) Human HEK293
Coiled-coil domain containing 134 (CCDC134) is a 229 amino acids secretory protein. Coiled-coil domain is a motif in which alpha-helix are coiled together. It has been found in many types of proteins, including transcrip...
TMPH-01525 CMAHP Protein, Human, Recombinant (His & Myc) Human E. coli
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate...
TMPK-00696 PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II) Human Baculovirus-Insect Cells
The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-...
TMPH-02187 Tenascin Protein, Human, Recombinant (E. coli, His) Human E. coli
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent prote...
TMPJ-00932 PBLD Protein, Human, Recombinant (His) Human E. coli
Phenazine Biosynthesis-Like Domain-Containing protein (PBLD) belongs to the phenazine biosynthesis-like protein (PhzF) family, which is expressed in most tissues. PBLD takes part in the MAPK signaling pathway, and is inv...
TMPH-02042 RHBDL2 Protein, Human, Recombinant (His) Human E. coli
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosph...
TMPY-02595 DUSP14 Protein, Human, Recombinant (His & MBP) Human E. coli
Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosph...
TMPJ-01315 IL-1RL2 Protein, Mouse, Recombinant (His) Mouse Human Cells
Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene, belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to i...
TMPJ-01314 IL-1RL2 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene, belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to i...
TMPH-02556 PLA2G5 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epit...
------------------------ More ------------------------
p38 delta/MAPK13 Protein, Human, Recombinant (GST)
TMPY-04551
Species: Human
Expression System: Baculovirus-Insect Cells
p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro
TMPY-04531
Species: Human
Expression System: Baculovirus-Insect Cells
ERK2 Protein, Human, Recombinant (GST)
TMPY-04539
Species: Human
Expression System: Baculovirus-Insect Cells
MBIPP Protein, Human, Recombinant (His)
TMPJ-01353
Species: Human
Expression System: E. coli
LAMTOR2 Protein, Human, Recombinant (His)
TMPY-02252
Species: Human
Expression System: E. coli
ERK2 Protein, Mouse, Recombinant (His & GST)
TMPY-04571
Species: Mouse
Expression System: Baculovirus-Insect Cells
p38 gamma/MAPK12 Protein, Human, Recombinant
TMPY-04430
Species: Human
Expression System: Baculovirus-Insect Cells
p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)
TMPY-04429
Species: Human
Expression System: Baculovirus-Insect Cells
Mp1 Protein, Human, Recombinant (His)
TMPJ-01378
Species: Human
Expression System: E. coli
LGALS1 Protein, Human, Recombinant (His)
TMPJ-00021
Species: Human
Expression System: E. coli
TrkB Protein, Human, Recombinant (His)
TMPY-00751
Species: Human
Expression System: HEK293
TrkB Protein, Mouse, Recombinant (His)
TMPY-02231
Species: Mouse
Expression System: HEK293
AMH Protein, Human, Recombinant (His)
TMPY-05176
Species: Human
Expression System: HEK293
EGFR Protein, Mouse, Recombinant (His)
TMPY-02676
Species: Mouse
Expression System: HEK293
EGFR Protein, Cynomolgus, Recombinant (His)
TMPY-04818
Species: Cynomolgus
Expression System: HEK293
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)
TMPY-04529
Species: Human
Expression System: Baculovirus-Insect Cells
EGFR Protein, Human, Recombinant (His)
TMPY-00742
Species: Human
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
TMPJ-00662
Species: Human
Expression System: E. coli
Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His)
TMPY-00665
Species: Human
Expression System: HEK293
TSPAN8 Protein, Human, Recombinant (His)
TMPY-03564
Species: Human
Expression System: HEK293
LIF Protein, Human, Recombinant (His)
TMPY-03532
Species: Human
Expression System: HEK293
MKK4 Protein, Mouse, Recombinant (His & GST)
TMPY-04572
Species: Mouse
Expression System: Baculovirus-Insect Cells
LIF Protein, Mouse, Recombinant
TMPY-04278
Species: Mouse
Expression System: HEK293
LIF Protein, Human, Recombinant
TMPY-04104
Species: Human
Expression System: HEK293
Pleiotrophin/PTN Protein, Mouse, Recombinant
TMPY-03577
Species: Mouse
Expression System: Baculovirus-Insect Cells
PDGFC Protein, Mouse, Recombinant (His)
TMPY-04976
Species: Mouse
Expression System: Yeast
Prolactin Receptor Protein, Human, Recombinant (His)
TMPY-01053
Species: Human
Expression System: HEK293
IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158)
TMPY-02879
Species: Human
Expression System: E. coli
TrkA Protein, Human, Recombinant (His)
TMPY-01084
Species: Human
Expression System: HEK293
Leptin Receptor Protein, Human, Recombinant (His)
TMPY-01725
Species: Human
Expression System: HEK293
Mucin-1/MUC1 Protein, Human, Recombinant
TMPY-04340
Species: Human
Expression System: HEK293
E-Selectin/CD62E Protein, Human, Recombinant (His)
TMPY-01167
Species: Human
Expression System: HEK293
Mucin-1/MUC1 Protein, Human, Recombinant (hFc)
TMPY-02005
Species: Human
Expression System: HEK293
CD25/IL2R alpha Protein, Rat, Recombinant (His)
TMPY-05090
Species: Rat
Expression System: Baculovirus-Insect Cells
CD25/IL2R alpha Protein, Human, Recombinant (His)
TMPY-01103
Species: Human
Expression System: HEK293
CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05584
Species: Human
Expression System: HEK293
CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His)
TMPY-03644
Species: Cynomolgus
Expression System: HEK293
CD25/IL2R alpha Protein, Cynomolgus, Recombinant
TMPY-03776
Species: Cynomolgus
Expression System: HEK293
CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated
TMPY-05644
Species: Rhesus
Expression System: HEK293
CD25/IL2R alpha Protein, Mouse, Recombinant (His)
TMPY-01923
Species: Mouse
Expression System: HEK293
CCDC134 Protein, Human, Recombinant (His)
TMPY-02551
Species: Human
Expression System: HEK293
CMAHP Protein, Human, Recombinant (His & Myc)
TMPH-01525
Species: Human
Expression System: E. coli
PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)
TMPK-00696
Species: Human
Expression System: Baculovirus-Insect Cells
Tenascin Protein, Human, Recombinant (E. coli, His)
TMPH-02187
Species: Human
Expression System: E. coli
PBLD Protein, Human, Recombinant (His)
TMPJ-00932
Species: Human
Expression System: E. coli
RHBDL2 Protein, Human, Recombinant (His)
TMPH-02042
Species: Human
Expression System: E. coli
DUSP14 Protein, Human, Recombinant (His & MBP)
TMPY-02595
Species: Human
Expression System: E. coli
IL-1RL2 Protein, Mouse, Recombinant (His)
TMPJ-01315
Species: Mouse
Expression System: Human Cells
IL-1RL2 Protein, Mouse, Recombinant (hFc)
TMPJ-01314
Species: Mouse
Expression System: Human Cells
PLA2G5 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02556
Species: Mouse
Expression System: E. coli
Cat No. Product Name
L1400 MAPK Inhibitor Library

367 compounds
A unique collection of 367 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;
L3600 Cytokine Inhibitor Library

613 compounds
A unique collection of 613 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;
L8500 HIF-1 Signaling Pathway Compound Library

1352 compounds
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;
L7700 Neural Regeneration Compound Library

529 compounds
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;
L7900 Osteogenesis Compound Library

320 compounds
A unique collection of 320 osteogenesis related compounds for high throughput and high content screening;
L1610 FDA-Approved Kinase Inhibitor Library

280 compounds
Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs with proven kinase inhibitory activity. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、...
L1310 Cytoskeletal Signaling Pathway Compound Library

773 compounds
A unique collection of 773 cytoskeleton-related compounds, can be used for HTS and HCS;
L1600 Kinase Inhibitor Library

2230 compounds
A unique collection of 2230 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases;
TargetMol