mcaalaprolys(dnp)oh

Mca-Ala-Pro-Lys(Dnp)-OH, a specific quenched fluorogenic substrate for ACE2, enables the detection of ACE2 activity in various tissues, including urinary, heart, and lung.

Mca-RPPGFSAFK(Dnp)-OH, a fluorogenic substrate specifically designed for endothelin-converting enzyme-1 (ECE-1), enables the quantification of ECE-1 activity through its distinctive fluorescence signal. When ECE-1 cleaves this substrate, it releases 7-methoxycoumarin-4-acetyl (Mca), which exhibits excitation and emission maxima at 328 nm and 420 nm, respectively, allowing for the direct measurement of enzyme activity.

Abz-SDK(Dnp)P-OH is a fluorescent peptide that functions as a substrate for the angiotensin I-converting enzyme (ACE). It features a fluorescent donor-acceptor pair comprising Abz and Dnp (2,4-dinitrophenyl) [1].

Mca-DEVDAPK(Dnp)-OH is a fluorescent substrate for caspase-3.

DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH serves as a substrate for the matrix metalloproteinase MMP-1, exhibiting a Michaelis constant (Km) of 26.61 μM. Additionally, this compound is employed as a fluorescence probe for monitoring protein activity [1].

Mca-YVADAP-Lys(Dnp)-OH serves as a fluorogenic substrate specifically for caspase-1 and angiotensin-converting enzyme 2 (ACE2) [1].

Mca-YVADAP-Lys(Dnp)-OH TFA is a fluorogenic substrate specifically used for caspase-1 and angiotensin-converting enzyme 2 (ACE2) [1].