Search Result

Search Results for " nf-kb "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T39965	NF-κΒ activator 1		NF-κB
	NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns. NF-κΒ is widely used in eukaryotic cells as a gene regulating cell proliferation and cell survival. NF-κΒ activator 1 induces superoxide ...		NF-κB
T39924	NF-κΒ activator 2		NF-κB
	NF-κΒ Activator 2 is a potent, orally active compound that efficiently activates NF-κB with an EC50 value of 1.58 μM. By enhancing NF-κB expression and activation, it induces SOD 2 synthesis, rendering it useful for amyo...		NF-κB
T9656	AP-1/NF-κB activation inhibitor 1		NF-κB , DNA/RNA Synthesis
	AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation in...		NF-κB , DNA/RNA Synthesis
T9105	NF-κB-IN-1	1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-	IκB/IKK , NF-κB
	NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 dir...		IκB/IKK , NF-κB
T27620	IP7e	IP 7e,IP-7e,isoxazolo-pyridinone 7e	Others
	IP7e (isoxazolo-pyridinone 7e) is a Nurr1 activator with an EC50 value of 3.9 nM.		Others
T37559	NF-κB Control
	NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It bloc...
T38153	NF-κB Inhibitor (trifluoroacetate salt)
	NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.1It blocks the...
T60357	NF-κB-IN-2	JEUD-38
	NF-κB-IN-2 inhibits canonical NF-κB signaling induced by TNF-α in PC-3 cells.
T20168	Aurothiomalate sodium	Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate	Others , PKC
	Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate ...		Others , PKC
T4543	Telithromycin	HMR3647,Ketek,RU66647	Antibacterial , Antibiotic
	Telithromycin (HMR3647) is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity. Antibacterial Telithromycin prevents bacteria from growing, by interfering with their protein synthesis...		Antibacterial , Antibiotic
T4361	CBL0137 hydrochloride	CBL0137,CBLC137,Curaxin 137,CBL-C137 hydrochloride,Curaxin-137 hydrochloride	Others , NF-κB , p53
	CBL0137 hydrochloride (Curaxin-137 hydrochloride) activates p53 and inhibits NF-kB (EC50: 0.37/0.47 μM) in the cell-based p53 and NF-kB reporter assays, respectively. It also suppresses histone chaperone FACT.		Others , NF-κB , p53
T21480	Diethylmaleate	Maleic acid, diethyl ester,DIETHYL MALEATE	NF-κB
	Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.		NF-κB
T8981	WAY-169916	WAY 169916,WAY169916	NF-κB
	WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER). It acts by inhibiting NF-kB transcriptional activity but being devoid of conventional estrogenic activity.		NF-κB
T8951	JTP 0819958 - HOIPIN-1		IκB/IKK
	JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM[1]. JTP-0819958 suppress LUBAC-mediated NF-kB activation in vitro[2].		IκB/IKK
T78557	HOIPIN-1	JTP0819958	NF-κB
	HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC50 >2.8 μM).HOIPIN-1 inhibits LUBAC-mediated NF-kB activation.		NF-κB
TP1615L	IKKγ NBD Inhibitory Peptide acetate	IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base)	NF-κB
	IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region. IKKγ NBD Inhibitory Peptide acetate is shown to block TNF-alpha-in...		NF-κB
T22115	SM-7368		NF-κB
	The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.		NF-κB
T0947	Dexamethasone acetate	Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471	Glucocorticoid Receptor , Mitophagy , IL Receptor , Annexin A , NOS , Antibacterial , Autophagy
	Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexa...
T0005	Aspirin	Acetylsalicylate,Acetylsalicylic Acid,ASA	Mitophagy , Virus Protease , COX , Autophagy
	Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel...		Mitophagy , Virus Protease , COX , Autophagy
T11096	DRI-C21045		NF-κB
	Dri-c21045 showed concentration-dependent inhibition of NF- B activation and all CD40L induced by B cell proliferation. IC50 was 17.1 M and 4.5 M, respectively.Dri-c21045 is an effective selective inhibitor of CD40-CD40L...		NF-κB
T11886	LTβR-IN-1		Others , NF-κB , LTR
	LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor. LTβR-IN-1 has a selective inhibitory effect on the nuclear translocation of p52 of TNF12A, and has no obvious effect on the nuclear translocation o...		Others , NF-κB , LTR
T5209	INH14		IκB/IKK
	INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).		IκB/IKK
T6964	Resiquimod	R848,S28463	HCV Protease , TLR
	Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti...		HCV Protease , TLR
T68729	Coumaperine
	Coumaperine is an NF-kB inhibitor.
T28065	ML263	ML-263,ML 263
	ML263 inhibits NF-kB activation induced by B-cell specific antigen receptor.
T29013	HE 3286	Triolex,HE-3286,HE3286
	Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.
TP1615	IKKγ NBD Inhibitory Peptide
	A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO ...
T63107	Anti-inflammatory agent 6
	Anti-inflammatory agent 6 exhibits anti-inflammatory potential by blocking the phosphorylation of Iκb kinase α/β (IKKα/β), IκBα and nuclear factor kB p65 (NF-κb p65), which are key controllers of inflammation.
T62359	TLR4/NF-κB/MAPK-IN-1
	TLR4/NF-κB/MAPK-IN-1 is a novel antineuroinflammatory agent that functions by inhibiting the TLR4/NF-κB/MAPK pathways.
T76024	IKKγ NBD Inhibitory Peptide TFA
	IKKγ NBD Inhibitory Peptide TFA is a specific NF-κB inhibitor that functions by hindering the interaction between the IKKγ/NEMO-binding domain (NBD) and IKKα and IKKβ. This action effectively prevents TNF-α-induced NF-kB...
T71827	AG-205
	(rac)-AG-205 serves as a robust inhibitor of the progesterone receptor membrane component 1 (Pgrmc1), crucial for inducing genes linked to sterol synthesis, notably the INSIG1 protein, which interacts with PGRMC1. Additi...
T11240	Ethacrynic acid D5		Others
	Ethacrynic acid, a diuretic, functions as an inhibitor of L-type voltage-dependent and store-operated calcium channels, facilitating the relaxation of airway smooth muscle (ASM) cells. It exhibits anti-inflammatory effec...		Others
T71285	Metaxalone-d6
	Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264...
T74895	Anti-inflammatory agent 31
	Anti-inflammatory agent 31 (enone 17), an andrographolide derivative, acts as an anti-inflammatory agent by inhibiting NF-κB activation through the upstream blockade of PI3K/Akt and ERK1/2 MAPK pathways. It effectively r...
T37449	SR 12460
	SR 12460 is a mimetic of the IκB kinase β (IKKβ) NEMO/IKKγ-binding domain (NBD) that inhibits the protein-protein interaction between the IKK complex subunits NF-κB essential modulator (NEMO/IKKγ) and IKKβ.1It inhibits T...

Compounds

AP-1/NF-κB activation inhibitor 1

T9656

Synonym:

Target: NF-κB, DNA/RNA Synthesis

NF-κB-IN-1

T9105

Synonym: 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-

Target: IκB/IKK, NF-κB

IP7e

T27620

Synonym: IP 7e,IP-7e,isoxazolo-pyridinone 7e

NF-κB Inhibitor (trifluoroacetate salt)

Aurothiomalate sodium

T20168

Synonym: Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate

Target: Others, PKC

Telithromycin

T4543

Synonym: HMR3647,Ketek,RU66647

Target: Antibacterial, Antibiotic

CBL0137 hydrochloride

T4361

Synonym: CBL0137,CBLC137,Curaxin 137,CBL-C137 hydrochloride,Curaxin-137 hydrochloride

Target: Others, NF-κB, p53

Diethylmaleate

T21480

Synonym: Maleic acid, diethyl ester,DIETHYL MALEATE

Target: NF-κB

WAY-169916

T8981

Synonym: WAY 169916,WAY169916

Target: NF-κB

JTP 0819958 - HOIPIN-1

IKKγ NBD Inhibitory Peptide acetate

TP1615L

Synonym: IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base)

Dexamethasone acetate

T0947

Synonym: Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy

Aspirin

T0005

Synonym: Acetylsalicylate,Acetylsalicylic Acid,ASA

Target: Mitophagy, Virus Protease, COX, Autophagy

Target: Others, NF-κB, LTR

Target: HCV Protease, TLR

Synonym: ML-263,ML 263

Target:

HE 3286

T29013

Synonym: Triolex,HE-3286,HE3286

Target:

IKKγ NBD Inhibitory Peptide

TP1615

Synonym:

Target:

Anti-inflammatory agent 6

IKKγ NBD Inhibitory Peptide TFA

Anti-inflammatory agent 31

Cat No.	Product Name	Synonyms	Targets
T2745	18α-Glycyrrhetinic acid	Enoxolone,Glycyrrhetinic acid	Apoptosis , NF-κB , Proteasome
	18α-Glycyrrhetinic acid (Enoxolone) is an inhibitor of NF-kB and an activator of the proteasome, and functions as a longevity-promoting and anti-aggregation factor in multicellular organisms. It induces apoptosis.		Apoptosis , NF-κB , Proteasome
T0335	Sodium salicylate	Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt	Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
	Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.		Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
T5727	CAFESTOL		ERK , NF-κB , COX , PGE Synthase
	CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production...		ERK , NF-κB , COX , PGE Synthase
T3000	Magnolol	NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol	NF-κB , Retinoid Receptor , Antibacterial , PPAR , p53 , Autophagy
	Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
T5754	Kavain		NF-κB , GABA Receptor
	Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors such as NF-kB and LITAF.		NF-κB , GABA Receptor
T3S1692	Octahydrocurcumin		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
	Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahy...		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
T5660	Menthone		IL Receptor , TNF , NF-κB , Parasite
	Menthone has anti-inflammary activity,, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha),as well as nuclear factor k...		IL Receptor , TNF , NF-κB , Parasite
TN6730	Epoxyazadiradione		NF-κB
	Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NF-kB in human cervical cancer cells.		NF-κB
T3913	Saikosaponin D		Estrogen Receptor/ERR , NF-κB , Antibacterial , STAT
	Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.		Estrogen Receptor/ERR , NF-κB , Antibacterial , STAT
T4S1540	Myrislignan		Apoptosis , NF-κB
	Myrislignan has anti-inflammatory, and anti-cancer activities, it inhibited NF-κB signalling pathway activation, inhibited the proliferation of A549 cells in a dose- and time-dependent manner, it also significantly induc...		Apoptosis , NF-κB
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
T7979	2-Hydroxychalcone	2-(2-Hydroxybenzal)Acetophenone	Apoptosis , BCL , Others , NF-κB
	2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated.It can inhibit invasion of triple negative breast cancer cells.		Apoptosis , BCL , Others , NF-κB
T7190	Actein		Apoptosis , Akt , JNK , Autophagy
	Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in...		Apoptosis , Akt , JNK , Autophagy
T5687	WITHAFERIN A		Ferroptosis , NF-κB
	WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/or cancer.		Ferroptosis , NF-κB
T5S0761	Nitidine chloride		Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
	1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T4S0969	Obtusifolin		Antioxidant , NF-κB
	1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be...		Antioxidant , NF-κB
T83358	3-Ethylthio withaferin A
	3-Ethylthio withaferin A, a derivative of Withaferin A, is a compound known for its inhibitory action on NF-κB (NF-kB).
TN1874	Liriodendrin		ATPase , Potassium Channel , Prostaglandin Receptor
	Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). Liriodendrin has anti-inflammatory, antinociceptive, hypoglycemic activities a...		ATPase , Potassium Channel , Prostaglandin Receptor
TN3709	Coronarin D ethyl ether		NF-κB
	Coronarin D inhibits NF-KB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis.It shows promising antifungal activity against C. albicans ...		NF-κB
T39077	Aeruginosin 865
	Aeruginosin 865, a compound extracted from the terrestrial cyanobacterium Nostoc sp. Luke ová 30/93, represents the inaugural aeruginosin-type peptide to incorporate a fatty acid and a carbohydrate moiety. It functions b...
TN3219	7,8-Didehydrocimigenol		ERK , IκB/IKK , TNF , NF-κB , Akt , PPAR
	7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of TNF-α-activated EC which leads to selective inhibition of V...		ERK , IκB/IKK , TNF , NF-κB , Akt , PPAR
T75491	3-(2-Hydroxyethyl) thio withaferin A
	3-(2-Hydroxyethyl) thio withaferin A, a derivative of Withaferin A, is a steroidal lactone that inhibits NF-kB activation and targets vimentin, showcasing potent anti-inflammatory and anticancer properties. It also acts ...
TN1104	Cyanidin 3-sambubioside chloride	Cyanidin-3-O-sambubioside chloride	NF-κB , ROS
	Cyanidin-3-O-sambubioside chloride is inhibitors of BPDE-induced NF-kB activity. It inhibits the enzyme activity by competing with the substrate for the active site. Cyanidin-3-O-sambubioside chloride has antioxidant act...		NF-κB , ROS
TN4194	Heliangin		IL Receptor , TNF , NF-κB , MAPK , Prostaglandin Receptor
	Heliangin shows anti-inflammatory effects, it can inhibit lipopolysaccharide-induced inflammation through signaling NF-ÎºB pathway on LPS-induced RAW 264.7 cells. Heliangin has anti-cancer activity, it exhibits cytotoxic...		IL Receptor , TNF , NF-κB , MAPK , Prostaglandin Receptor
TN5153	Torilin		MMP , ERK , IκB/IKK , p38 MAPK , NF-κB , Tyrosinase , Reductase , DNA/RNA Synthesis , JNK
	Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic acid (IC50 = 160.3 +/- 24.62 microM) but is weaker than fi...

Natural Products

18α-Glycyrrhetinic acid

T2745

Synonym: Enoxolone,Glycyrrhetinic acid

Target: Apoptosis, NF-κB, Proteasome

Sodium salicylate

T0335

Synonym: Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt

Target: Apoptosis, NF-κB, COX, S6 Kinase, Autophagy

CAFESTOL

T5727

Synonym:

Target: ERK, NF-κB, COX, PGE Synthase

Magnolol

T3000

Synonym: NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol

Target: NF-κB, Retinoid Receptor, Antibacterial, PPAR, p53, Autophagy

Kavain

T5754

Synonym:

Target: NF-κB, GABA Receptor

Octahydrocurcumin

T3S1692

Synonym:

Target: Anti-infection, NF-κB, Reactive Oxygen Species, ROS

Menthone

T5660

Synonym:

Target: IL Receptor, TNF, NF-κB, Parasite

Target: Estrogen Receptor/ERR, NF-κB, Antibacterial, STAT

Myrislignan

T4S1540

Synonym:

Target: Apoptosis, NF-κB

Polygalasaponin F

T3826

Synonym:

Target: NF-κB, TLR, Akt, PI3K

2-Hydroxychalcone

T7979

Synonym: 2-(2-Hydroxybenzal)Acetophenone

Target: Apoptosis, BCL, Others, NF-κB

Actein

T7190

Synonym:

Target: Apoptosis, Akt, JNK, Autophagy

WITHAFERIN A

T5687

Synonym:

Target: Ferroptosis, NF-κB

Nitidine chloride

T5S0761

Synonym:

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

Obtusifolin

T4S0969

Synonym:

Target: Antioxidant, NF-κB

3-Ethylthio withaferin A

Target: ATPase, Potassium Channel, Prostaglandin Receptor

Coronarin D ethyl ether

7,8-Didehydrocimigenol

TN3219

Synonym:

Target: ERK, IκB/IKK, TNF, NF-κB, Akt, PPAR

3-(2-Hydroxyethyl) thio withaferin A

T75491

Synonym:

Target:

Cyanidin 3-sambubioside chloride

TN1104

Synonym: Cyanidin-3-O-sambubioside chloride

Target: IL Receptor, TNF, NF-κB, MAPK, Prostaglandin Receptor

Torilin

TN5153

Synonym:

Target: MMP, ERK, IκB/IKK, p38 MAPK, NF-κB, Tyrosinase, Reductase, DNA/RNA Synthesis, JNK

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02387	NF-kB p65 Protein, Human, Recombinant (aa 1-306, GST)	Human	E. coli
	RELA (v-rel reticuloendotheliosis viral oncogene homolog A), also known as Nuclear factor NF-kappa-B p65 subunit, or Transcription factor p65, is a transcription factor expressed in growth plate chondrocytes where it fac...
TMPK-00723	RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPK-00351	RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)	Human	HEK293
	TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPJ-00674	RANK/TNFRSF11A Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member of tumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acid...
TMPJ-00349	RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)	Human	Human Cells
	Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANK...
TMPY-02879	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158)	Human	E. coli
	Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a...
TMPY-00988	Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-00873	Lipocalin-2/LCN2 Protein, Human, Recombinant (His)	Human	HEK293
	Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-01710	IkB alpha/NFKBIA Protein, Human, Recombinant (His)	Human	E. coli
	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NF...
TMPJ-00464	APE Protein, Human, Recombinant	Human	E. coli
	Apurinic-Apyrimidinic Endonuclease 1 (APE1) is required for efficient DNA base excision repair. When the DNA glycosylase remove the damaged bases, APE1 cleaves the AP site to allow resynthesis and ligation to complete re...
TMPY-01956	IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a...
TMPY-02818	IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His)	Human	E. coli
	Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a...
TMPY-01176	CIAP1 Protein, Human, Recombinant (Avi)	Human	E. coli
	The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP r...
TMPH-02169	TRBC1 Protein, Human, Recombinant (His)	Human	Yeast
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02170	TRBC1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02167	TRAC Protein, Human, Recombinant (His)	Human	Yeast
	Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize p...
TMPH-02172	TRBC2 Protein, Human, Recombinant (His)	Human	Yeast
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02171	TRBC2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02173	TRBC2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-02168	TRAC Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize p...
TMPY-05203	Lipocalin-2/LCN2 Protein, Mouse, Recombinant	Mouse	HEK293
	Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-02316	Lipocalin-2/LCN2 Protein, Rat, Recombinant (His)	Rat	Baculovirus-Insect Cells
	Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...

NF-kB p65 Protein, Human, Recombinant (aa 1-306, GST)

TMPY-02387

Species: Human

Expression System: E. coli

RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)

TMPK-00723

Species: Mouse

Expression System: HEK293

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)

TMPK-00351

Species: Human

Expression System: HEK293

RANK/TNFRSF11A Protein, Mouse, Recombinant (His)

TMPJ-00674

Species: Mouse

Expression System: Human Cells

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)

TMPJ-00349

Species: Human

Expression System: Human Cells

IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158)

TMPY-02879

Species: Human

Expression System: E. coli

Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His)

TMPY-00988

Species: Mouse

Expression System: HEK293

Lipocalin-2/LCN2 Protein, Human, Recombinant (His)

TMPY-00873

Species: Human

Expression System: HEK293

IkB alpha/NFKBIA Protein, Human, Recombinant (His)

TMPY-01710

Species: Human

Expression System: E. coli

APE Protein, Human, Recombinant

TMPJ-00464

Species: Human

Expression System: E. coli

IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant

TMPY-01956

Species: Mouse

Expression System: E. coli

IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His)

TMPY-02818

Species: Human

Expression System: E. coli

cIAP1 Protein, Human, Recombinant (Avi)

TMPY-01176

Species: Human

Expression System: E. coli

TRBC1 Protein, Human, Recombinant (His)

TMPH-02169

Species: Human

Expression System: Yeast

TRBC1 Protein, Human, Recombinant (His & Myc)

TMPH-02170

Species: Human

Expression System: E. coli

TRAC Protein, Human, Recombinant (His)

TMPH-02167

Species: Human

Expression System: Yeast

TRBC2 Protein, Human, Recombinant (His)

TMPH-02172

Species: Human

Expression System: Yeast

TRBC2 Protein, Human, Recombinant (hFc)

TMPH-02171

Species: Human

Expression System: HEK293

TRBC2 Protein, Human, Recombinant (His & Myc)

TMPH-02173

Species: Human

Expression System: E. coli

TRAC Protein, Human, Recombinant (E. coli, His)

TMPH-02168

Species: Human

Expression System: E. coli

Lipocalin-2/LCN2 Protein, Mouse, Recombinant

TMPY-05203

Species: Mouse

Expression System: HEK293

Lipocalin-2/LCN2 Protein, Rat, Recombinant (His)

TMPY-02316

Species: Rat

Expression System: Baculovirus-Insect Cells

Cat No.	Product Name
L3800	NF-κB Signaling Compound Library	740 compounds
	A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L3600	Cytokine Inhibitor Library	613 compounds
	A unique collection of 613 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;
L4700	Immunology/Inflammation Compound Library	3483 compounds
	A unique collection of 3483 anti-inflammation compounds effective for high throughput screening and high content screening.

Libraries

NF-κB Signaling Compound Library

L3800

Compounds: 740

Cytokine Inhibitor Library

L3600

Compounds: 613

Immunology/Inflammation Compound Library

L4700

Compounds: 3483