Home Tools
Log in
Cart

Search Result

Search Results for " nf-kb "

35

Compounds

25

Natural Products

19

Recombinant Proteins

3

Libraries

Cat No. Product Name Synonyms Targets
T39965 NF-κΒ activator 1 NF-κB
NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns. NF-κΒ is widely used in eukaryotic cells as a gene regulating cell proliferation and cell survival. NF-κΒ activator 1 induces superoxide ...
T39924 NF-κΒ activator 2 NF-κB
NF-κΒ activator 2 is a potent and orally active NF-κB activator, with an EC 50 of 1.58 μM. NF-κΒ activator 2 induces SOD 2 through increasing NF-κB expression and activation. NF-κΒ activator 2 can be used for the researc...
T9656 AP-1/NF-κB activation inhibitor 1 NF-κB , DNA/RNA Synthesis
AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation in...
T9105 NF-κB-IN-1 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)- IκB/IKK , NF-κB
NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 dir...
T27620 IP7e IP 7e,IP-7e,isoxazolo-pyridinone 7e Others
IP7e (isoxazolo-pyridinone 7e) is a Nurr1 activator with an EC50 value of 3.9 nM.
T37559 NF-κB Control
NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It bloc...
T38153 NF-κB Inhibitor (trifluoroacetate salt)
NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.1It blocks the...
T60357 NF-κB-IN-2 JEUD-38
NF-κB-IN-2 inhibits canonical NF-κB signaling induced by TNF-α in PC-3 cells.
T20168 Aurothiomalate sodium Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate Others , PKC
Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate ...
T4543 Telithromycin HMR3647,Ketek,RU66647 Antibacterial , Antibiotic
Telithromycin (HMR3647) is a ketolide antibiotic to treat community acquired pneumonia of mild to moderate severity. Antibacterial Telithromycin prevents bacteria from growing, by interfering with their protein synthesis...
T4361 CBL0137 hydrochloride CBL0137,CBLC137,Curaxin 137,CBL-C137 hydrochloride,Curaxin-137 hydrochloride Others , NF-κB , p53
CBL0137 hydrochloride (Curaxin-137 hydrochloride) activates p53 and inhibits NF-kB (EC50: 0.37/0.47 μM) in the cell-based p53 and NF-kB reporter assays, respectively. It also suppresses histone chaperone FACT.
T21480 Diethylmaleate Maleic acid, diethyl ester,DIETHYL MALEATE NF-κB
Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.
T8981 WAY-169916 WAY 169916,WAY169916 NF-κB
WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER). It acts by inhibiting NF-kB transcriptional activity but being devoid of conventional estrogenic activity.
T8951 JTP 0819958 - HOIPIN-1 IκB/IKK
JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM[1]. JTP-0819958 suppress LUBAC-mediated NF-kB activation in vitro[2].
T78557 HOIPIN-1 JTP0819958 NF-κB
HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC50 >2.8 μM).HOIPIN-1 inhibits LUBAC-mediated NF-kB activation.
TP1615L IKKγ NBD Inhibitory Peptide acetate IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base) NF-κB
IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region. IKKγ NBD Inhibitory Peptide acetate is shown to block TNF-alpha-in...
T22115 SM-7368 NF-κB
The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.
T0947 Dexamethasone acetate Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471 Glucocorticoid Receptor , Mitophagy , IL Receptor , Annexin A , NOS , Antibacterial , Autophagy
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexa...
T0005 Aspirin Acetylsalicylate,Acetylsalicylic Acid,ASA Mitophagy , Virus Protease , COX , Autophagy
Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel...
T11096 DRI-C21045 NF-κB
Dri-c21045 showed concentration-dependent inhibition of NF- B activation and all CD40L induced by B cell proliferation. IC50 was 17.1 M and 4.5 M, respectively.Dri-c21045 is an effective selective inhibitor of CD40-CD40L...
T11886 LTβR-IN-1 Others , NF-κB , LTR
LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor. LTβR-IN-1 has a selective inhibitory effect on the nuclear translocation of p52 of TNF12A, and has no obvious effect on the nuclear translocation o...
T5209 INH14 IκB/IKK
INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).
T6964 Resiquimod R848,S28463 HCV Protease , TLR
Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti...
T68729 Coumaperine
Coumaperine is an NF-kB inhibitor.
T28065 ML263 ML-263,ML 263
ML263 inhibits NF-kB activation induced by B-cell specific antigen receptor.
T62359 TLR4/NF-κB/MAPK-IN-1
TLR4/NF-κB/MAPK-IN-1 is a new type of antineuroinflammatory agent by suppressing TLR4/NF-kB/MAPK pathways.
T29013 HE 3286 Triolex,HE-3286,HE3286
Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.
TP1615 IKKγ NBD Inhibitory Peptide
A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO ...
T63107 Anti-inflammatory agent 6
Anti-inflammatory agent 6 exhibits anti-inflammatory potential by blocking the phosphorylation of Iκb kinase α/β (IKKα/β), IκBα and nuclear factor kB p65 (NF-κb p65), which are key controllers of inflammation.
T71827 AG-205
(rac)-AG-205 is a potent inhibitor of progesterone receptor membrane component 1 ( Pgrmc1 ) that induces genes involved in sterol synthesis, including the INSIG1 protein, which forms a complex with PGRMC1. (rac)-AG-205 p...
T76024 IKKγ NBD Inhibitory Peptide TFA
IKKγ NBD Inhibitory Peptide TFA is a highly specific inhibitor NF-κB inhibitor. IKKγ NBD Inhibitory Peptide TFA acts by disrupting the interaction between IKKγ/NEMO-binding domain (NBD) with IKKα and IKKβ, thus blocking ...
T11240 Ethacrynic acid D5 Others
Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid has anti-inflammatory properties that reduces the reti...
T71285 Metaxalone-d6
Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264...
T74895 Anti-inflammatory agent 31
Anti-inflammatory agent 31 (enone 17) is a kind of andrographolide derivatives, is a anti-inflammatory agent. Anti-inflammatory agent 31 inhibits NF-κB activation by upstream blockade of PI3K/Akt and ERK1/2 MAPK activati...
T37449 SR 12460
SR 12460 is a mimetic of the IκB kinase β (IKKβ) NEMO/IKKγ-binding domain (NBD) that inhibits the protein-protein interaction between the IKK complex subunits NF-κB essential modulator (NEMO/IKKγ) and IKKβ.1It inhibits T...

Compounds

NF-κΒ activator 1
T39965
Synonym:
Target: NF-κB
NF-κΒ activator 2
T39924
Synonym:
Target: NF-κB
AP-1/NF-κB activation inhibitor 1
T9656
Synonym:
Target: NF-κB, DNA/RNA Synthesis
NF-κB-IN-1
T9105
Synonym: 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-
Target: IκB/IKK, NF-κB
IP7e
T27620
Synonym: IP 7e,IP-7e,isoxazolo-pyridinone 7e
Target: Others
NF-κB Control
T37559
Synonym:
Target:
NF-κB Inhibitor (trifluoroacetate salt)
T38153
Synonym:
Target:
NF-κB-IN-2
T60357
Synonym: JEUD-38
Target:
Aurothiomalate sodium
T20168
Synonym: Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate
Target: Others, PKC
Telithromycin
T4543
Synonym: HMR3647,Ketek,RU66647
Target: Antibacterial, Antibiotic
CBL0137 hydrochloride
T4361
Synonym: CBL0137,CBLC137,Curaxin 137,CBL-C137 hydrochloride,Curaxin-137 hydrochloride
Target: Others, NF-κB, p53
Diethylmaleate
T21480
Synonym: Maleic acid, diethyl ester,DIETHYL MALEATE
Target: NF-κB
WAY-169916
T8981
Synonym: WAY 169916,WAY169916
Target: NF-κB
JTP 0819958 - HOIPIN-1
T8951
Synonym:
Target: IκB/IKK
HOIPIN-1
T78557
Synonym: JTP0819958
Target: NF-κB
IKKγ NBD Inhibitory Peptide acetate
TP1615L
Synonym: IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base)
Target: NF-κB
SM-7368
T22115
Synonym:
Target: NF-κB
Dexamethasone acetate
T0947
Synonym: Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471
Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy
Aspirin
T0005
Synonym: Acetylsalicylate,Acetylsalicylic Acid,ASA
Target: Mitophagy, Virus Protease, COX, Autophagy
DRI-C21045
T11096
Synonym:
Target: NF-κB
LTβR-IN-1
T11886
Synonym:
Target: Others, NF-κB, LTR
INH14
T5209
Synonym:
Target: IκB/IKK
Resiquimod
T6964
Synonym: R848,S28463
Target: HCV Protease, TLR
Coumaperine
T68729
Synonym:
Target:
ML263
T28065
Synonym: ML-263,ML 263
Target:
TLR4/NF-κB/MAPK-IN-1
T62359
Synonym:
Target:
HE 3286
T29013
Synonym: Triolex,HE-3286,HE3286
Target:
IKKγ NBD Inhibitory Peptide
TP1615
Synonym:
Target:
Anti-inflammatory agent 6
T63107
Synonym:
Target:
AG-205
T71827
Synonym:
Target:
IKKγ NBD Inhibitory Peptide TFA
T76024
Synonym:
Target:
Ethacrynic acid D5
T11240
Synonym:
Target: Others
Metaxalone-d6
T71285
Synonym:
Target:
Anti-inflammatory agent 31
T74895
Synonym:
Target:
SR 12460
T37449
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T0335 Sodium salicylate Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.
T5727 CAFESTOL ERK , NF-κB , COX , PGE Synthase
CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production...
T3000 Magnolol NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol NF-κB , Retinoid Receptor , Antibacterial , PPAR , p53 , Autophagy
Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
T5754 Kavain NF-κB , GABA Receptor
Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors such as NF-kB and LITAF.
T3S1692 Octahydrocurcumin Anti-infection , NF-κB , Reactive Oxygen Species , ROS
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahy...
T5660 Menthone IL Receptor , TNF , NF-κB , Parasite
Menthone has anti-inflammary activity,, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha),as well as nuclear factor k...
TN6730 Epoxyazadiradione NF-κB
Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NF-kB in human cervical cancer cells.
T3913 Saikosaponin D Estrogen Receptor/ERR , NF-κB , Antibacterial , STAT
Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.
T4S1540 Myrislignan Apoptosis , NF-κB
Myrislignan has anti-inflammatory, and anti-cancer activities, it inhibited NF-κB signalling pathway activation, inhibited the proliferation of A549 cells in a dose- and time-dependent manner, it also significantly induc...
T3826 Polygalasaponin F NF-κB , TLR , Akt , PI3K
Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...
T7190 Actein Apoptosis , Akt , JNK , Autophagy
Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in...
T7979 2-Hydroxychalcone 2-(2-Hydroxybenzal)Acetophenone Apoptosis , BCL , Others , NF-κB
2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated.It can inhibit invasion of triple negative breast cancer cells.
T5687 WITHAFERIN A Ferroptosis , NF-κB
WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/or cancer.
T5S0761 Nitidine chloride Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T2745 18α-Glycyrrhetinic acid Enoxolone,Glycyrrhetinic acid Apoptosis , NF-κB , Proteasome
18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb licorice. It is used in flavoring a...
T4S0969 Obtusifolin Antioxidant , NF-κB
1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be...
T83358 3-Ethylthio withaferin A
3-Ethylthio withaferin A, a derivative of Withaferin A, is a compound known for its inhibitory action on NF-κB (NF-kB).
TN1874 Liriodendrin ATPase , Potassium Channel , Prostaglandin Receptor
Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). Liriodendrin has anti-inflammatory, antinociceptive, hypoglycemic activities a...
TN3709 Coronarin D ethyl ether NF-κB
Coronarin D inhibits NF-KB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis.It shows promising antifungal activity against C. albicans ...
T39077 Aeruginosin 865
Aeruginosin 865, isolated from terrestrial cyanobacterium Nostoc sp . Luke ová 30/93, is the first aeruginosin-type peptide containing both a fatty acid and a carbohydrate moiety. Aeruginosin 865 inhibits translocation o...
T75491 3-(2-Hydroxyethyl) thio withaferin A
3-(2-Hydroxyethyl) thio withaferin A is a Withaferin A derivative. Withaferin A, a steroidal lactone, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A i...
TN3219 7,8-Didehydrocimigenol ERK , IκB/IKK , TNF , NF-κB , Akt , PPAR
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of TNF-α-activated EC which leads to selective inhibition of V...
TN1104 Cyanidin 3-sambubioside chloride Cyanidin-3-O-sambubioside chloride NF-κB , ROS
Cyanidin-3-O-sambubioside chloride is inhibitors of BPDE-induced NF-kB activity. It inhibits the enzyme activity by competing with the substrate for the active site. Cyanidin-3-O-sambubioside chloride has antioxidant act...
TN4194 Heliangin IL Receptor , TNF , NF-κB , MAPK , Prostaglandin Receptor
Heliangin shows anti-inflammatory effects, it can inhibit lipopolysaccharide-induced inflammation through signaling NF-κB pathway on LPS-induced RAW 264.7 cells. Heliangin has anti-cancer activity, it exhibits cytotoxic...
TN5153 Torilin MMP , ERK , IκB/IKK , p38 MAPK , NF-κB , Tyrosinase , Reductase , DNA/RNA Synthesis , JNK
Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic acid (IC50 = 160.3 +/- 24.62 microM) but is weaker than fi...

Natural Products

Sodium salicylate
T0335
Synonym: Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt
Target: Apoptosis, NF-κB, COX, S6 Kinase, Autophagy
CAFESTOL
T5727
Synonym:
Target: ERK, NF-κB, COX, PGE Synthase
Magnolol
T3000
Synonym: NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol
Target: NF-κB, Retinoid Receptor, Antibacterial, PPAR, p53, Autophagy
Kavain
T5754
Synonym:
Target: NF-κB, GABA Receptor
Octahydrocurcumin
T3S1692
Synonym:
Target: Anti-infection, NF-κB, Reactive Oxygen Species, ROS
Menthone
T5660
Synonym:
Target: IL Receptor, TNF, NF-κB, Parasite
Epoxyazadiradione
TN6730
Synonym:
Target: NF-κB
Saikosaponin D
T3913
Synonym:
Target: Estrogen Receptor/ERR, NF-κB, Antibacterial, STAT
Myrislignan
T4S1540
Synonym:
Target: Apoptosis, NF-κB
Polygalasaponin F
T3826
Synonym:
Target: NF-κB, TLR, Akt, PI3K
Actein
T7190
Synonym:
Target: Apoptosis, Akt, JNK, Autophagy
2-Hydroxychalcone
T7979
Synonym: 2-(2-Hydroxybenzal)Acetophenone
Target: Apoptosis, BCL, Others, NF-κB
WITHAFERIN A
T5687
Synonym:
Target: Ferroptosis, NF-κB
Nitidine chloride
T5S0761
Synonym:
Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite
18α-Glycyrrhetinic acid
T2745
Synonym: Enoxolone,Glycyrrhetinic acid
Target: Apoptosis, NF-κB, Proteasome
Obtusifolin
T4S0969
Synonym:
Target: Antioxidant, NF-κB
3-Ethylthio withaferin A
T83358
Synonym:
Target:
Liriodendrin
TN1874
Synonym:
Target: ATPase, Potassium Channel, Prostaglandin Receptor
Coronarin D ethyl ether
TN3709
Synonym:
Target: NF-κB
Aeruginosin 865
T39077
Synonym:
Target:
3-(2-Hydroxyethyl) thio withaferin A
T75491
Synonym:
Target:
7,8-Didehydrocimigenol
TN3219
Synonym:
Target: ERK, IκB/IKK, TNF, NF-κB, Akt, PPAR
Cyanidin 3-sambubioside chloride
TN1104
Synonym: Cyanidin-3-O-sambubioside chloride
Target: NF-κB, ROS
Heliangin
TN4194
Synonym:
Target: IL Receptor, TNF, NF-κB, MAPK, Prostaglandin Receptor
Torilin
TN5153
Synonym:
Target: MMP, ERK, IκB/IKK, p38 MAPK, NF-κB, Tyrosinase, Reductase, DNA/RNA Synthesis, JNK

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-00723 RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc) Mouse HEK293
TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPY-02387 NF-kB p65 Protein, Human, Recombinant (aa 1-306, GST) Human E. coli
RELA (v-rel reticuloendotheliosis viral oncogene homolog A), also known as Nuclear factor NF-kappa-B p65 subunit, or Transcription factor p65, is a transcription factor expressed in growth plate chondrocytes where it fac...
TMPK-00351 RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc) Human HEK293
TNFRSF11A, also known as receptor activator of NF-κB (RANK), activates several signaling pathways, such as NF-κB, JNK, ERK, p38α, and Akt/PKB. RANK/TNFRSF11A is a novel and frequent target for de novo methylation in glio...
TMPJ-00674 RANK/TNFRSF11A Protein, Mouse, Recombinant (His) Mouse Human Cells
Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member of tumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acid...
TMPJ-00349 RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His) Human Human Cells
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANK...
TMPY-02879 IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158) Human E. coli
Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a...
TMPY-00988 Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His) Mouse HEK293
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-00873 Lipocalin-2/LCN2 Protein, Human, Recombinant (His) Human HEK293
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-01710 IkB alpha/NFKBIA Protein, Human, Recombinant (His) Human E. coli
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NF...
TMPJ-00464 APE Protein, Human, Recombinant Human E. coli
Apurinic-Apyrimidinic Endonuclease 1 (APE1) is required for efficient DNA base excision repair. When the DNA glycosylase remove the damaged bases, APE1 cleaves the AP site to allow resynthesis and ligation to complete re...
TMPY-01956 IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant Mouse E. coli
Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a...
TMPY-02818 IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His) Human E. coli
Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a...
TMPY-01176 CIAP1 Protein, Human, Recombinant (Avi) Human E. coli
The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP r...
TMPH-01952 SPRY2 Protein, Human, Recombinant (His & Myc) Human E. coli
Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-01950 PML Protein, Human, Recombinant (His) Human E. coli
Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-01951 S100A7A Protein, Human, Recombinant (His) Human Yeast
Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPH-01953 SSX1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize pe...
TMPY-05203 Lipocalin-2/LCN2 Protein, Mouse, Recombinant Mouse HEK293
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-02316 Lipocalin-2/LCN2 Protein, Rat, Recombinant (His) Rat Baculovirus-Insect Cells
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
RANK/TNFRSF11A Protein, Mouse, Recombinant (hFc)
TMPK-00723
Species: Mouse
Expression System: HEK293
NF-kB p65 Protein, Human, Recombinant (aa 1-306, GST)
TMPY-02387
Species: Human
Expression System: E. coli
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, hFc)
TMPK-00351
Species: Human
Expression System: HEK293
RANK/TNFRSF11A Protein, Mouse, Recombinant (His)
TMPJ-00674
Species: Mouse
Expression System: Human Cells
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
TMPJ-00349
Species: Human
Expression System: Human Cells
IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158)
TMPY-02879
Species: Human
Expression System: E. coli
Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His)
TMPY-00988
Species: Mouse
Expression System: HEK293
Lipocalin-2/LCN2 Protein, Human, Recombinant (His)
TMPY-00873
Species: Human
Expression System: HEK293
IkB alpha/NFKBIA Protein, Human, Recombinant (His)
TMPY-01710
Species: Human
Expression System: E. coli
APE Protein, Human, Recombinant
TMPJ-00464
Species: Human
Expression System: E. coli
IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant
TMPY-01956
Species: Mouse
Expression System: E. coli
IL-36 alpha/IL-1F6 Protein, Human, Recombinant (His)
TMPY-02818
Species: Human
Expression System: E. coli
cIAP1 Protein, Human, Recombinant (Avi)
TMPY-01176
Species: Human
Expression System: E. coli
SPRY2 Protein, Human, Recombinant (His & Myc)
TMPH-01952
Species: Human
Expression System: E. coli
PML Protein, Human, Recombinant (His)
TMPH-01950
Species: Human
Expression System: E. coli
S100A7A Protein, Human, Recombinant (His)
TMPH-01951
Species: Human
Expression System: Yeast
SSX1 Protein, Human, Recombinant (His & SUMO)
TMPH-01953
Species: Human
Expression System: E. coli
Lipocalin-2/LCN2 Protein, Mouse, Recombinant
TMPY-05203
Species: Mouse
Expression System: HEK293
Lipocalin-2/LCN2 Protein, Rat, Recombinant (His)
TMPY-02316
Species: Rat
Expression System: Baculovirus-Insect Cells
Cat No. Product Name
L3800 NF-κB Signaling Compound Library

740 compounds
A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L3600 Cytokine Inhibitor Library

613 compounds
A unique collection of 613 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;
L4700 Immunology/Inflammation Compound Library

3483 compounds
A unique collection of 3483 anti-inflammation compounds effective for high throughput screening and high content screening.
TargetMol