Search Result

Search Results for "p38 mapk"

Targets

Libraries

MAPK Inhibitor Library AMPK-Targeted Compound Library FDA-Approved Kinase Inhibitor Library Kinase Inhibitor Library Cytokine Inhibitor Library HIF-1 Signaling Pathway Compound Library Osteogenesis Compound Library Neural Regeneration Compound Library Cytoskeletal Signaling Pathway Compound Library High Solubility FragLite Fragment Library Glycometabolism Compound Library Anti-Cancer Metabolism Compound Library Microtubule-Targeted Compound Library

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Compounds

Cat No.	Product Name
T12997	SR-318		TNF , p38 MAPK
	SR-318 is a potent and highly selective inhibitor of p38 MAPK(IC50s of 5 nM, 32 nM and 6.11 μM for p38α, p38β and p38α/β...		TNF , p38 MAPK
T39823L	Apelin-12 acetate		Apelin receptor , p38 MAPK , JNK
	Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor. Apelin-12 acetate inhibits the JNK and p38 ...		Apelin receptor , p38 MAPK , JNK
T5S1058	Triptonide	PG 492 , NSC 165677	Apoptosis , Wnt/beta-catenin , Autophagy
	1. Triptonide is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities....		Apoptosis , Wnt/beta-catenin , Autophagy
T6429	Caffeic Acid Phenethyl Ester	CAPE , Phenylethyl Caffeate	NF-κB , Apoptosis
	Caffeic Acid Phenethyl Ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress ...		NF-κB , Apoptosis
T7661	SD-169	SD 169	p38 MAPK
	SD 169 is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.		p38 MAPK
TL0004	FERULIC ACID METHYL ESTER	Methyl ferulate , Methyl 4'-hydroxy-3'-methoxycinnamate	p38 MAPK , Autophagy
	Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis)...		p38 MAPK , Autophagy
T61803	p38 MAPK-IN-3
	p38 MAPK-IN-3 (Compound 2c) is a p38α MAPK inhibitor. p38 MAPK-IN-3 has antitumor activities and induces apoptosis and R...
T22710	DBM 1285 dihydrochloride		Others
	p38 MAPK inhibitor		Others
TN4635	Neoechinulin A		p38 MAPK , NOS , TNF , NF-κB , NADPH-oxidase , Beta Amyloid , IκB/IKK , ASK , COX , Prostaglandin Receptor
	Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-ÎºB...
T12667	(Rac)-Hesperetin		Others
	(Rac)-Hesperetin is the racemate of Hesperetin.Hesperetin induces apoptosis via p38 MAPK activation. Hesperetin is a na...		Others
T61755	E6201
	E6201 (ER-806201) is an ATP-competitive dual kinase inhibitor of MEK1 and FLT3. E6201 inhibits MEK1- induced ERK2 phosph...
TN5174	Trichosanatine		LDL , p38 MAPK , Lipoxygenase , ROS , MMP
	Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process...		LDL , p38 MAPK , Lipoxygenase , ROS , MMP
T41240	Verrucarin A
	Verrucarin A (Muconomycin A), a Type D macrocyclic mycotoxin derived from the pathogen fungus Myrothecium verrucaria, is...
T38048	Globotetraosylceramides (porcine RBC)
	Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes. ...
T35536	Tpl2 Kinase Inhibitor (hydrochloride)
	Tpl2 kinase inhibitor is an inhibitor of tumor progression locus 2 (Tpl2; IC50= 0.05 μM).1It is selective for Tpl2 over ...
T37581	SCIO 469 hydrochloride
	Selective, ATP-competitive p38 inhibitor (IC50 = 9 nM for p38α in vitro). Displays approximately 10-fold selectivity for...
T38665	OVA-E1 peptide TFA		p38 MAPK , JNK
	OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.		p38 MAPK , JNK
T35463	(±)14(15)-EET	(±)14,15-EpETrE , (±)14,15-EET
	(±)14(15)-EET is a metabolite of arachidonic acid that is formed via epoxidation of arachidonic acid by cytochrome P450....
T36010	p38 MAPK Inhibitor		p38 MAPK
	p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogen...		p38 MAPK
T35420	(S)-p38 MAPK Inhibitor III
	(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). It is ce...