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Search Results for " trna "

Targets

75

Compounds

23

Natural Products

43

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T10303 Aminoacyl tRNA synthetase-IN-1 Others
Aminoacyl tRNA synthetase-IN-1 is an inhibitor of bacterial aminoacyl tRNA synthetase (aaRS).
T63688 Isoleucyl tRNA synthetase-IN-1
Isoleucyl tRNA synthetase-IN-1 is a selective and potent inhibitor (Ki: 88 nM) that targets isoleucyl tRNA synthetase (IleRS).
T74612 Aminoacyl tRNA synthetase-IN-2
Aminoacyl tRNA synthetase-IN-2 (Compound 14) is an aminoacyl-tRNA synthetase (aaRS) inhibitor. Aminoacyl tRNA synthetase-IN-2 can be used for development of a new family of antibiotics [1] .
T63706 Isoleucyl tRNA synthetase-IN-2
Isoleucyl tRNA synthetase-IN-2 is a selective and potent inhibitor (Ki: 114 nM) that targets isoleucyl tRNA synthetase (IleRS).
T9533 BC-LI-0186 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide Others
BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protei...
T9726 2’-OMe-Guanosine Apoptosis , Nucleoside Antimetabolite/Analog
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.
T41286 N6-Isopentenyladenosine Endogenous Metabolite , Autophagy
N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity. N6-Isopentenyladenosine, an RNA modification found in cytokinins, regulates plant growth/different...
T16698 Pyronin Y C.I. 45005,Pyronine G Others
Pyronin Y (Pyronine G) is an intercalating cationic dye that shows specificity towards RNA.
T0788L Spectinomycin dihydrochloride pentahydrate Trobicin,Spectogard,Spectinomycin hydrochloride hydrate ribosome , Antibacterial , Antibiotic
Spectinomycin dihydrochloride pentahydrate (Spectogard) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
T78227 L-Methioninamide hydrochloride DNA/RNA Synthesis
L-Methioninamide hydrochloride is a potent inhibitor of methionyl-tRNA synthetase that reduces the toxicity of CDDP.
T11919 LysRs-IN-1 9-carboxymethylguanine Others
LysRs-IN-1 is an inhibitor of Lysyl-tRNA synthetase (LysRs).
T8629 N-BENZYL-2-PHENYLETHYLAMINE Others
N-BENZYL-2-PHENYLETHYLAMINE is an inhibitor of rel+ Escherichia coli B Phe-tRNA.
T19464 N6,N6-Dimethyladenosine Nucleoside Antimetabolite/Analog
N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.
T4045 Epetraborole hydrochloride GSK2251052 hydrochloride Antibacterial
Epetraborole hydrochloride (GSK2251052 hydrochloride) is a potent and selective leucyl-tRNA synthetase inhibitor.
T50026 Aquacycline HSV
Oxytetracycline (OTC) is a broad-spectrum antibiotic that acts by inhibiting protein synthesis in bacteria. Oxytetracycline prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also po...
T20121 L-Albizziin NSC-132089,L-beta-Ureidoalanine,L-Albizziine,Albizzine,NSC 132089,Albizziin Glutaminase
L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.
T3052 Sancycline Bonomycin,Norcycline,Sancyclinum,6-Demethyl-6-deoxytetracycline Antibacterial
Sancycline (Bonomycin) is a rare semi-synthetic tetracycline, acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site.
T1569 Tigecycline GAR-936 ribosome , Antibacterial , Antibiotic , Autophagy
Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome co...
T8785 HALOFUGINONE LACTATE DNA/RNA Synthesis , TGF-beta/Smad
HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner ...
TNU0130 2'-O-Methyl-2-thiouridine Nucleoside Antimetabolite/Analog
2'-O-Methyl-2-thiouridine is a purine nucleoside analogue present in synthetic thermophilic bacterial tRNAs. 2'-O-Methyl-2-thiouridine is more selective for A than unmodified U.
T8404 Kasugamycin hydrochloride hydrate Ksg (hydrochloride hydrate) Antibacterial , Antibiotic
Kasugamycin hydrochloride hydrate (Ksg (hydrochloride hydrate))(Ksg) specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs. Ksg inhibition is thought to occur by direct competitio...
T31932 GJ071 oxalate GJ 071,GJ-071,GJ071 Others
GJ071 oxalate is a Nonsense suppressor. Nonsense suppressors (NonSups) induce “readthrough”, i.e., the selection of near cognate tRNAs at premature termination codons and insertion of the corresponding amino acid into na...
T22774L Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) Others
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub...
T11920 LysRs-IN-2 Others
LysRs-IN-2 is a lysyl-tRNA synthetase (KRS) inhibitor with IC50s of 0.13 μM and 0.015 μM for Cryptosporidium parvum lysyl-tRNA synthetase (CpKRS) and Plasmodium falciparum lysyl-tRNA synthetase (PfKRS), respectively.
T11403L Gln-AMS TFA (209543-57-7 free base) Gln-AMS TFA Others
Gln-AMS(TFA) inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 μM. Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor.
T26001 Pulvomycin Antibiotic 1063Z
Pulvomycin is a protein biosynthesis inhibitor preventing ternary complex formation between elongation factor Tu, GTP, and aminoacyl-tRNA.
T64165 Gln-AMS TFA
Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.
T26178 SB-217452 SB217452
SB-217452 is a potent seryl tRNA synthetase inhibitor isolated from Streptomyces.
T11403 Gln-AMS Others
Gln-AMS is an inhibitor of aminoacyl-tRNA synthetases (AARS). It specifically binds to the A-domain located within the NRPS enzymes.
T72349 Antibacterial agent 91
Antibacterial agent 91 is a triple-site aminoacyl-tRNA synthetase (aaRS) inhibitor with an IC 50 of 2.10 μM against Salmonella enterica threonyl-tRNA synthetase ( Se ThrRS) . Antibacterial agent 91 exhibits antibacteri...
T72350 Antibacterial agent 92
Antibacterial agent 92 is a triple-site aminoacyl-tRNA synthetase (aaRS) inhibitor with an IC 50 of 0.58 μM against Salmonella enterica threonyl-tRNA synthetase ( Se ThrRS) . Antibacterial agent 92 exhibits antibacteri...
T33511 Ms2i6A ms2i6-2-6,ms2i6 2 6
ms2i6A is a mitochondrial tRNA-specific modification, which regulates efficient mitochondrial translation and energy metabolism in mammals.
T11434 GlyRS-IN-1 Others
GlyRS-IN-1 is an inhibitor of glycyl-tRNA synthase (GlyRS). It can inhibit the growth of bacteria.
T69800 T-3861174
T-3861174 is a prolyl tRNA synthetase (PRS) inhibitor, exhibiting significant in vitro anti-tumor activity with GCN2-ATF4 pathway activation.
T21052 Lysidine 2-Methyl-2-iMidazoline Nucleoside Antimetabolite/Analog
Lysidine (2-Methyl-2-iMidazoline) is a nucleoside rarely seen outside of tRNA. Lysidine has better translation fidelity.
T60974 MetRS-IN-1
MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].
T40561 ThrRS-IN-2
ThrRS-IN-2 is a threonyl-tRNA synthetase (ThrRS) inhibitor with an IC 50 value of 56.5 ± 3.5 μM.
T27088 CRS-3123 REP-3123,REP 3123,CRS 3123
CRS-3123, a methionyl-tRNA synthetase inhibitor, is used potentially for the treatment of enteric infections.
T71168 Epetraborole R-Mandelate
Epetraborole R-Mandelate is a potent and selective leucyl-tRNA synthetase inhibitor.
T11497 Ganfeborole HCl GSK3036656 HCl,GSK656 HCl Antibacterial
Ganfeborole HCl (GSK3036656 HCl) is a small molecule compound with anti-tuberculosis activity and is an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS; IC50: 0.2 μM).
T10386 Asp-AMS Others
Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor.
T69741 DWN-12088 HCl
DWN-12088 HCl is the salt form of DWN-12088 Free Base, an orally administered small molecule prolyl-tRNA synthetase (PRS) inhibitor
T30311 Bederocin REP 8839,REP-8839,REP8839 Antibacterial
Bederocin (REP8839)is a novel inhibitor of methionyl tRNA synthase (METS) with potent antibacterial activity against clinical isolates of Staphylococcus aureus, Streptococcus pyogenes, and other clinically important Gram...
T26314 Valyl-ochratoxin A
Valyl-ochratoxin A is a phenylalanyl moiety of ochratoxin A replaced by valine. It is a yeast valyl-tRNA synthetase inhibitor.
T61676 4-Piperidinecarboxamide
4-Piperidinecarboxamide is a mycobacterial aspartyl-tRNA synthetase (AspS) inhibitor and a potential anti-tuberculosis (TB) agent [1].
T72303 Antibacterial agent 124
Antibacterial agent 124 is a potent bacterial prolyl-tRNA synthetase (ProRS) inhibitor with an IC 50 of 0.18 μM against Staphylococcus aureus ProRS ( Sa ProRS) .
T63376 CB 168
CB 168 is a potent selective aminoacylaminoaryl tetrazole inhibitor targeting isoleucine tRNA synthetase (IleRS).
T60405 GSK-3036656 free base GSK656 HCl,GSK 3036656,GSK656,GSK-3036656,GSK-656,GSK 656
GSK656 (GSK3036656) shows potent inhibition of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS) (IC50 = 0.20 μM) which has potential for the treatment of tuberculosis [1].
T73123 ThrRS-IN-3
ThrRS-IN-3 is a highly potent threonyl-tRNA synthetase (ThrRS) inhibitor, with an IC 50 value of 19 nM and a K d of 34 nM for Salmonella enterica ThrRS. ThrRS-IN-3 has antibacterial activities .
T18863 UAA crosslinker 1 hydrochloride Others
UAA crosslinker 1 hydrochloride is an amber codon used to incorporate non-canonical amino acids (ncAAs) into proteins in vivo. This is achieved by leveraging the promiscuous activity of specific wildtype and engineered a...

Compounds

Aminoacyl tRNA synthetase-IN-1
T10303
Synonym:
Target: Others
Isoleucyl tRNA synthetase-IN-1
T63688
Synonym:
Target:
Aminoacyl tRNA synthetase-IN-2
T74612
Synonym:
Target:
Isoleucyl tRNA synthetase-IN-2
T63706
Synonym:
Target:
BC-LI-0186
T9533
Synonym: 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide
Target: Others
2’-OMe-Guanosine
T9726
Synonym:
Target: Apoptosis, Nucleoside Antimetabolite/Analog
N6-Isopentenyladenosine
T41286
Synonym:
Target: Endogenous Metabolite, Autophagy
Pyronin Y
T16698
Synonym: C.I. 45005,Pyronine G
Target: Others
Spectinomycin dihydrochloride pentahydrate
T0788L
Synonym: Trobicin,Spectogard,Spectinomycin hydrochloride hydrate
Target: ribosome, Antibacterial, Antibiotic
L-Methioninamide hydrochloride
T78227
Synonym:
Target: DNA/RNA Synthesis
LysRs-IN-1
T11919
Synonym: 9-carboxymethylguanine
Target: Others
N-BENZYL-2-PHENYLETHYLAMINE
T8629
Synonym:
Target: Others
N6,N6-Dimethyladenosine
T19464
Synonym:
Target: Nucleoside Antimetabolite/Analog
Epetraborole hydrochloride
T4045
Synonym: GSK2251052 hydrochloride
Target: Antibacterial
Aquacycline
T50026
Synonym:
Target: HSV
L-Albizziin
T20121
Synonym: NSC-132089,L-beta-Ureidoalanine,L-Albizziine,Albizzine,NSC 132089,Albizziin
Target: Glutaminase
Sancycline
T3052
Synonym: Bonomycin,Norcycline,Sancyclinum,6-Demethyl-6-deoxytetracycline
Target: Antibacterial
Tigecycline
T1569
Synonym: GAR-936
Target: ribosome, Antibacterial, Antibiotic, Autophagy
HALOFUGINONE LACTATE
T8785
Synonym:
Target: DNA/RNA Synthesis, TGF-beta/Smad
2'-O-Methyl-2-thiouridine
TNU0130
Synonym:
Target: Nucleoside Antimetabolite/Analog
Kasugamycin hydrochloride hydrate
T8404
Synonym: Ksg (hydrochloride hydrate)
Target: Antibacterial, Antibiotic
GJ071 oxalate
T31932
Synonym: GJ 071,GJ-071,GJ071
Target: Others
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA)
T22774L
Synonym:
Target: Others
LysRs-IN-2
T11920
Synonym:
Target: Others
Gln-AMS TFA (209543-57-7 free base)
T11403L
Synonym: Gln-AMS TFA
Target: Others
Pulvomycin
T26001
Synonym: Antibiotic 1063Z
Target:
Gln-AMS TFA
T64165
Synonym:
Target:
SB-217452
T26178
Synonym: SB217452
Target:
Gln-AMS
T11403
Synonym:
Target: Others
Antibacterial agent 91
T72349
Synonym:
Target:
Antibacterial agent 92
T72350
Synonym:
Target:
ms2i6A
T33511
Synonym: ms2i6-2-6,ms2i6 2 6
Target:
GlyRS-IN-1
T11434
Synonym:
Target: Others
T-3861174
T69800
Synonym:
Target:
Lysidine
T21052
Synonym: 2-Methyl-2-iMidazoline
Target: Nucleoside Antimetabolite/Analog
MetRS-IN-1
T60974
Synonym:
Target:
ThrRS-IN-2
T40561
Synonym:
Target:
CRS-3123
T27088
Synonym: REP-3123,REP 3123,CRS 3123
Target:
Epetraborole R-Mandelate
T71168
Synonym:
Target:
Ganfeborole HCl
T11497
Synonym: GSK3036656 HCl,GSK656 HCl
Target: Antibacterial
Asp-AMS
T10386
Synonym:
Target: Others
DWN-12088 HCl
T69741
Synonym:
Target:
Bederocin
T30311
Synonym: REP 8839,REP-8839,REP8839
Target: Antibacterial
Valyl-ochratoxin A
T26314
Synonym:
Target:
4-Piperidinecarboxamide
T61676
Synonym:
Target:
Antibacterial agent 124
T72303
Synonym:
Target:
CB 168
T63376
Synonym:
Target:
GSK-3036656 free base
T60405
Synonym: GSK656 HCl,GSK 3036656,GSK656,GSK-3036656,GSK-656,GSK 656
Target:
ThrRS-IN-3
T73123
Synonym:
Target:
UAA crosslinker 1 hydrochloride
T18863
Synonym:
Target: Others
1 2
Cat No. Product Name Synonyms Targets
T0895 Oxytetracycline Terramycin ribosome , Endogenous Metabolite , Antibacterial , Antibiotic , HSV
Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.
T6624 Oxytetracycline Dihydrate Terramycin Dihydrate Others , Endogenous Metabolite , Antibacterial , Antibiotic , HSV
Oxytetracycline Dihydrate (Terramycin Dihydrate) is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.
T0788 Spectinomycin dihydrochloride Spectinomycin 2HCl,Actinospectacin ribosome , Antibacterial , Antibiotic
Spectinomycin dihydrochloride (Actinospectacin) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
T21430 Oxytetracycline Hydrochloride Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin Antiviral , Endogenous Metabolite , Antibacterial , HSV
Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resultin...
T6856 Halofuginone Tempostatin,empostatin,RU-19110 Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T3524 Halofuginone hydrobromide Tempostatin,RU-19110 (hydrobromide),Stenorol Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T7514 N2-Methylguanosine Nucleoside Antimetabolite/Analog , Endogenous Metabolite
N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's
T19083 1-Methylinosine N1-Methylinosine,Inosine, 1-methyl Nucleoside Antimetabolite/Analog , Endogenous Metabolite
1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite.
T19146 5,6-Dihydrouridine Endogenous Metabolite
5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Eukaryota, Bacteria, and some Archaea.
T0912L Tetracycline Deschlorobiomycin,Tetracyclinum,Tetracyclin Others , ribosome , Antibacterial , Antibiotic
Tetracycline (Tetracyclin) is a naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
TN7106 2′-O-Methyluridine Others
2′-O-Methyluridine is a natural product that found in RNA such as rRNA, snRNA, snoRNA and tRNA in Archaea, Bacteria, and Eukaryota.
T4456 N4-Acetylcytidine N-Acetylcytidine Others , Endogenous Metabolite
N4-Acetylcytidine (N-Acetylcytidine) is a modified nucleoside. N4-acetylcytidine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary nucleosides are biological mark...
T6447 Clindamycin Clinimycin,Sobelin,Chlolincocin Antibacterial , Antibiotic
Clindamycin (Sobelin) dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. Clindamycin is a semisynthetic broad-spectrum antibiotic produced by chemical modification of t...
T5055 For-Met-OH fMet,N-Formyl-L-methionine Others , Endogenous Metabolite
For-Met-OH (N-Formyl-L-methionine) is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formyl methionyl tRNA. This process occurs in Escherichia coli and other ...
T6599 N6-methyladenosine N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A Others , Influenza Virus , Endogenous Metabolite
N6-methyladenosine (NSC-29409) is a methylated adenine residue. N6-Methyladenosine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary nucleosides are biological ma...
T0912 Tetracycline hydrochloride NCI-c55561,Tetracycline HCl ribosome , Antibacterial , Antibiotic
Tetracycline hydrochloride (NCI-c55561) is the hydrochloride salt of the tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium ...
TL0005 3,5-O-Dicaffeoylquinic acid Isochlorogenic Acid A,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid Others
3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) is an isolated compound from Artemisia argyi; its ester derivatives exert anti-leucyl-tRNA synthetase of Giardia lamblia (GlLeuRS) and potential anti-giardial effects. ...
TQ0193 N2,N2-Dimethylguanosine Endogenous Metabolite
N2,N2-Dimethylguanosine is an urinary nucleoside. The mean levels of urinary N2,N2-Dimethylguanosine in patients with colorectal cancer are significantly higher than those in patients with intestinal villous adenoma or h...
T1304 Chlortetracycline hydrochloride Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride ribosome , Antibacterial , Antibiotic
Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride (Isphamycin) is bacteriostatic and inhibits bacterial protein synthesis by b...
T2762 Kasugamycin hydrochloride Kasumin Antibacterial , Antibiotic , Antifungal
Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydr...
T10582 Borrelidin Treponemycin Others
Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor. It is a macrolide antibiotic isolated from Streptomyces rochei.
T34765 T6A N-(6-Nebularinylcarbamoyl)threonine,t 6 A,t-6-A,t(6)A,N6-Threonylcarbamoyladenosine Others
T6A (N6-Threonylcarbamoyladenosine) is a ubiquitously conserved nucleoside, which is essential for modification. T6A is found in the tRNA responsible for transporting the ANN codon.
T13304 Virginiamycin S1 Others
Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation.

Natural Products

Oxytetracycline
T0895
Synonym: Terramycin
Target: ribosome, Endogenous Metabolite, Antibacterial, Antibiotic, HSV
Oxytetracycline Dihydrate
T6624
Synonym: Terramycin Dihydrate
Target: Others, Endogenous Metabolite, Antibacterial, Antibiotic, HSV
Spectinomycin dihydrochloride
T0788
Synonym: Spectinomycin 2HCl,Actinospectacin
Target: ribosome, Antibacterial, Antibiotic
Oxytetracycline Hydrochloride
T21430
Synonym: Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin
Target: Antiviral, Endogenous Metabolite, Antibacterial, HSV
Halofuginone
T6856
Synonym: Tempostatin,empostatin,RU-19110
Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Halofuginone hydrobromide
T3524
Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
N2-Methylguanosine
T7514
Synonym:
Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite
1-Methylinosine
T19083
Synonym: N1-Methylinosine,Inosine, 1-methyl
Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite
5,6-Dihydrouridine
T19146
Synonym:
Target: Endogenous Metabolite
Tetracycline
T0912L
Synonym: Deschlorobiomycin,Tetracyclinum,Tetracyclin
Target: Others, ribosome, Antibacterial, Antibiotic
2′-O-Methyluridine
TN7106
Synonym:
Target: Others
N4-Acetylcytidine
T4456
Synonym: N-Acetylcytidine
Target: Others, Endogenous Metabolite
Clindamycin
T6447
Synonym: Clinimycin,Sobelin,Chlolincocin
Target: Antibacterial, Antibiotic
For-Met-OH
T5055
Synonym: fMet,N-Formyl-L-methionine
Target: Others, Endogenous Metabolite
N6-methyladenosine
T6599
Synonym: N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A
Target: Others, Influenza Virus, Endogenous Metabolite
Tetracycline hydrochloride
T0912
Synonym: NCI-c55561,Tetracycline HCl
Target: ribosome, Antibacterial, Antibiotic
3,5-O-Dicaffeoylquinic acid
TL0005
Synonym: Isochlorogenic Acid A,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid
Target: Others
N2,N2-Dimethylguanosine
TQ0193
Synonym:
Target: Endogenous Metabolite
Chlortetracycline hydrochloride
T1304
Synonym: Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride
Target: ribosome, Antibacterial, Antibiotic
Kasugamycin hydrochloride
T2762
Synonym: Kasumin
Target: Antibacterial, Antibiotic, Antifungal
Borrelidin
T10582
Synonym: Treponemycin
Target: Others
T6A
T34765
Synonym: N-(6-Nebularinylcarbamoyl)threonine,t 6 A,t-6-A,t(6)A,N6-Threonylcarbamoyladenosine
Target: Others
Virginiamycin S1
T13304
Synonym:
Target: Others

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05305 Alanyl-tRNA synthetase Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Alanyl-tRNA synthetase (AARS) belongs to the family of ligases, specifically those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. This enzyme participates in alanine and aspartate metabolism and ami...
TMPY-02441 Alanyl-tRNA synthetase Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Alanyl-tRNA synthetase (AARS) belongs to the family of ligases, specifically those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. This enzyme participates in alanine and aspartate metabolism and ami...
TMPY-01461 EMAP-II/AIMP1 Protein, Human, Recombinant (His) Human E. coli
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, also known as Multisynthase complex auxiliary component p43, Endothelial monocyte-activating polypeptide II, AIMP1, EMAP2 and SCYE1, is a nucleus pro...
TMPJ-01122 KARS Protein, Human, Recombinant (His) Human Human Cells
Lysine-tRNA ligase, also known as Lysyl-tRNA synthetase, LysRS, KARS and KIAA0070, belongs to the class-II aminoacyl-tRNA synthetase family. The N-terminal cytoplasmic domain (1-65) is a functional tRNA-binding domain, w...
TMPY-03393 DARS Protein, Human, Recombinant (His) Human E. coli
Aspartate tRNA ligase 1, also known as DARS, is part of a multienzyme complex of aminoacyl-tRNA synthetases. It belongs to the class-II aminoacyl-tRNA synthetase family. DARS charges its cognate tRNA with aspartate durin...
TMPY-05413 HARS/HisRS Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
TMPH-00313 tRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) Brugia malayi E. coli
TMPY-03753 WARS Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
WARS, also known as TrpRS, is an aminoacyl-tRNA synthetase that belongs to the class-I aminoacyl-tRNA synthetase family. There are two forms of tryptophanyl-tRNA synthetase: a cytoplasmic form, named WARS, and a mitochon...
TMPY-03448 AARSD1 Protein, Human, Recombinant (His) Human E. coli
AARSD1 belongs to the class-II aminoacyl-tRNA synthetase family, Alax-L subfamily. AARSD1 binds 1 zinc ion per subunit functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). Four transcri...
TMPY-01306 DNMT2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evo...
TMPJ-01241 DTD1 Protein, Human, Recombinant (His) Human Human Cells
D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is...
TMPY-03572 PTRH2 Protein, Human, Recombinant (His) Human E. coli
PTH2, also known as PTRH2, is a mitochondrial protein that belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs whic...
TMPY-03015 EMAP-II/AIMP1 Protein, Mouse, Recombinant Mouse E. coli
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, also known as Multisynthase complex auxiliary component p43, Endothelial monocyte-activating polypeptide II, AIMP1, EMAP2 and SCYE1, is a nucleus pro...
TMPH-01631 DCP2 Protein, Human, Recombinant (His) Human E. coli
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
TMPH-01630 LOXL3 Protein, Human, Recombinant (GST & His) Human E. coli
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
TMPH-01407 Glypican 1/GPC1 Protein, Human, Recombinant (GST & His & Myc) Human E. coli
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
TMPH-03712 Clp1 Protein, Xenopus laevis, Recombinant (His) Xenopus laevis E. coli
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated mo...
TMPY-03976 EEF1E1 Protein, Human, Recombinant (His) Human E. coli
EEF1E1, also known as AIMP3 and p18, is a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, EEF1E1 is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex...
TMPH-02875 ROMO1 Protein, Mouse, Recombinant (His) Mouse in vitro E. coli expression system
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP s...
TMPH-00732 RtcB Protein, E. coli, Recombinant (His) E. coli Yeast
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
TMPH-02044 RHOG Protein, Human, Recombinant (His & Myc) Human E. coli
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
TMPY-04108 EIF5A Protein, Human, Recombinant (His) Human E. coli
EIF-5A, also known as EIF5, functions in start site selection as a GTPase accelerating protein (GAP) for the eukaryotic translation initiation factor (eIF) 2•GTP•tRNA ternary complex within the ribosome-bound pre-initiat...
TMPH-01166 CGAS Protein, Human, Recombinant (His) Human E. coli
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly form...
TMPY-03184 EIF5 Protein, Human, Recombinant (GST) Human E. coli
EIF-5A, also known as EIF5, functions in start site selection as a GTPase accelerating protein (GAP) for the eukaryotic translation initiation factor (eIF) 2•GTP•tRNA ternary complex within the ribosome-bound pre-initiat...
TMPH-02256 Trypsin-3 Protein, Human, Recombinant (His) Human E. coli
Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S...
TMPH-00519 StxB Protein, Enterobacteria phage H19B, Recombinant (His) Enterobacteria phage H19B E. coli
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, where it has be...
TMPH-00019 BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO) Acinetobacter baumannii E. coli
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
TMPH-02214 Tomoregulin-1 Protein, Human, Recombinant (His) Human HEK293
Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
TMPH-03461 IFM1 Protein, S. cerevisiae, Recombinant (GST) Saccharomyces cerevisiae E. coli
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis o...
TMPH-03742 EEF1A1 Protein, Cricetulus griseus, Recombinant (His) Chinese hamster E. coli
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF...
TMPH-03125 Saposin-B-Val Protein, Pig, Recombinant (Flag & His) Sus scrofa (Pig) Yeast
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis o...
TMPY-01661 METTL1 Protein, Human, Recombinant (His) Human E. coli
tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein that belongs to the methyltransferase superfamily and TrmB family. M...
TMPH-01541 ITIH4 Protein, Human, Recombinant (His) Human Yeast
Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylat...
TMPH-02696 GNAQ Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase acti...
TMPH-01167 CDK1 Protein, Human, Recombinant (His) Human E. coli
Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochon...
TMPH-01164 ATF3 Protein, Human, Recombinant (His) Human E. coli
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF...
TMPH-00672 Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His) E. coli E. coli
GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splici...
TMPH-00633 Heat-stable enterotoxin A2 Protein, E. coli, Recombinant (His & Myc & SUMO) E. coli E. coli
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and sel...
TMPY-02551 CCDC134 Protein, Human, Recombinant (His) Human HEK293
Coiled-coil domain containing 134 (CCDC134) is a 229 amino acids secretory protein. Coiled-coil domain is a motif in which alpha-helix are coiled together. It has been found in many types of proteins, including transcrip...
TMPJ-00973 EIF1AX Protein, Human, Recombinant (His) Human E. coli
Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding of the 43S complex (a 40S...
TMPJ-00763 ANG Protein, Human, Recombinant Human E. coli
Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular t...
TMPY-03608 EEF1B2 Protein, Human, Recombinant (His) Human E. coli
EF1B, also known as EEF1B2, is a translation elongation factor. It belongs to the EF-1-beta/EF-1-delta family. Elongation factors are a set of proteins that are used in protein synthesis in the cell. In the ribosome, the...
TMPH-02885 SOSTDC1 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2. Hydrolyzes adenosin...
alanyl-tRNA synthetase Protein, Human, Recombinant (His)
TMPY-05305
Species: Human
Expression System: Baculovirus-Insect Cells
alanyl-tRNA synthetase Protein, Mouse, Recombinant (His)
TMPY-02441
Species: Mouse
Expression System: Baculovirus-Insect Cells
EMAP-II/AIMP1 Protein, Human, Recombinant (His)
TMPY-01461
Species: Human
Expression System: E. coli
KARS Protein, Human, Recombinant (His)
TMPJ-01122
Species: Human
Expression System: Human Cells
DARS Protein, Human, Recombinant (His)
TMPY-03393
Species: Human
Expression System: E. coli
HARS/HisRS Protein, Human, Recombinant (His)
TMPY-05413
Species: Human
Expression System: Baculovirus-Insect Cells
tRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His)
TMPH-00313
Species: Brugia malayi
Expression System: E. coli
WARS Protein, Human, Recombinant (His)
TMPY-03753
Species: Human
Expression System: Baculovirus-Insect Cells
AARSD1 Protein, Human, Recombinant (His)
TMPY-03448
Species: Human
Expression System: E. coli
DNMT2 Protein, Human, Recombinant (GST)
TMPY-01306
Species: Human
Expression System: Baculovirus-Insect Cells
DTD1 Protein, Human, Recombinant (His)
TMPJ-01241
Species: Human
Expression System: Human Cells
PTRH2 Protein, Human, Recombinant (His)
TMPY-03572
Species: Human
Expression System: E. coli
EMAP-II/AIMP1 Protein, Mouse, Recombinant
TMPY-03015
Species: Mouse
Expression System: E. coli
DCP2 Protein, Human, Recombinant (His)
TMPH-01631
Species: Human
Expression System: E. coli
LOXL3 Protein, Human, Recombinant (GST & His)
TMPH-01630
Species: Human
Expression System: E. coli
Glypican 1/GPC1 Protein, Human, Recombinant (GST & His & Myc)
TMPH-01407
Species: Human
Expression System: E. coli
Clp1 Protein, Xenopus laevis, Recombinant (His)
TMPH-03712
Species: Xenopus laevis
Expression System: E. coli
EEF1E1 Protein, Human, Recombinant (His)
TMPY-03976
Species: Human
Expression System: E. coli
ROMO1 Protein, Mouse, Recombinant (His)
TMPH-02875
Species: Mouse
Expression System: in vitro E. coli expression system
RtcB Protein, E. coli, Recombinant (His)
TMPH-00732
Species: E. coli
Expression System: Yeast
RHOG Protein, Human, Recombinant (His & Myc)
TMPH-02044
Species: Human
Expression System: E. coli
EIF5A Protein, Human, Recombinant (His)
TMPY-04108
Species: Human
Expression System: E. coli
CGAS Protein, Human, Recombinant (His)
TMPH-01166
Species: Human
Expression System: E. coli
EIF5 Protein, Human, Recombinant (GST)
TMPY-03184
Species: Human
Expression System: E. coli
Trypsin-3 Protein, Human, Recombinant (His)
TMPH-02256
Species: Human
Expression System: E. coli
StxB Protein, Enterobacteria phage H19B, Recombinant (His)
TMPH-00519
Species: Enterobacteria phage H19B
Expression System: E. coli
BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO)
TMPH-00019
Species: Acinetobacter baumannii
Expression System: E. coli
Tomoregulin-1 Protein, Human, Recombinant (His)
TMPH-02214
Species: Human
Expression System: HEK293
IFM1 Protein, S. cerevisiae, Recombinant (GST)
TMPH-03461
Species: Saccharomyces cerevisiae
Expression System: E. coli
EEF1A1 Protein, Cricetulus griseus, Recombinant (His)
TMPH-03742
Species: Chinese hamster
Expression System: E. coli
Saposin-B-Val Protein, Pig, Recombinant (Flag & His)
TMPH-03125
Species: Sus scrofa (Pig)
Expression System: Yeast
METTL1 Protein, Human, Recombinant (His)
TMPY-01661
Species: Human
Expression System: E. coli
ITIH4 Protein, Human, Recombinant (His)
TMPH-01541
Species: Human
Expression System: Yeast
GNAQ Protein, Mouse, Recombinant (His & Myc)
TMPH-02696
Species: Mouse
Expression System: E. coli
CDK1 Protein, Human, Recombinant (His)
TMPH-01167
Species: Human
Expression System: E. coli
ATF3 Protein, Human, Recombinant (His)
TMPH-01164
Species: Human
Expression System: E. coli
Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His)
TMPH-00672
Species: E. coli
Expression System: E. coli
Heat-stable enterotoxin A2 Protein, E. coli, Recombinant (His & Myc & SUMO)
TMPH-00633
Species: E. coli
Expression System: E. coli
CCDC134 Protein, Human, Recombinant (His)
TMPY-02551
Species: Human
Expression System: HEK293
EIF1AX Protein, Human, Recombinant (His)
TMPJ-00973
Species: Human
Expression System: E. coli
ANG Protein, Human, Recombinant
TMPJ-00763
Species: Human
Expression System: E. coli
EEF1B2 Protein, Human, Recombinant (His)
TMPY-03608
Species: Human
Expression System: E. coli
SOSTDC1 Protein, Mouse, Recombinant (His & Myc)
TMPH-02885
Species: Mouse
Expression System: E. coli
TargetMol