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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10303 | Aminoacyl tRNA synthetase-IN-1 | Others | |
Aminoacyl tRNA synthetase-IN-1 is an inhibitor of bacterial aminoacyl tRNA synthetase (aaRS). | |||
T63688 | Isoleucyl tRNA synthetase-IN-1 | ||
Isoleucyl tRNA synthetase-IN-1 is a selective and potent inhibitor (Ki: 88 nM) that targets isoleucyl tRNA synthetase (IleRS). | |||
T74612 | Aminoacyl tRNA synthetase-IN-2 | ||
Aminoacyl tRNA synthetase-IN-2 (Compound 14) is an aminoacyl-tRNA synthetase (aaRS) inhibitor. Aminoacyl tRNA synthetase-IN-2 can be used for development of a new family of antibiotics [1] . | |||
T63706 | Isoleucyl tRNA synthetase-IN-2 | ||
Isoleucyl tRNA synthetase-IN-2 is a selective and potent inhibitor (Ki: 114 nM) that targets isoleucyl tRNA synthetase (IleRS). | |||
T9533 | BC-LI-0186 | 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide | Others |
BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protei... | |||
T9726 | 2’-OMe-Guanosine | Apoptosis , Nucleoside Antimetabolite/Analog | |
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect. | |||
T41286 | N6-Isopentenyladenosine | Endogenous Metabolite , Autophagy | |
N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity. N6-Isopentenyladenosine, an RNA modification found in cytokinins, regulates plant growth/different... | |||
T16698 | Pyronin Y | C.I. 45005,Pyronine G | Others |
Pyronin Y (Pyronine G) is an intercalating cationic dye that shows specificity towards RNA. | |||
T0788L | Spectinomycin dihydrochloride pentahydrate | Trobicin,Spectogard,Spectinomycin hydrochloride hydrate | ribosome , Antibacterial , Antibiotic |
Spectinomycin dihydrochloride pentahydrate (Spectogard) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea. | |||
T78227 | L-Methioninamide hydrochloride | DNA/RNA Synthesis | |
L-Methioninamide hydrochloride is a potent inhibitor of methionyl-tRNA synthetase that reduces the toxicity of CDDP. | |||
T11919 | LysRs-IN-1 | 9-carboxymethylguanine | Others |
LysRs-IN-1 is an inhibitor of Lysyl-tRNA synthetase (LysRs). | |||
T8629 | N-BENZYL-2-PHENYLETHYLAMINE | Others | |
N-BENZYL-2-PHENYLETHYLAMINE is an inhibitor of rel+ Escherichia coli B Phe-tRNA. | |||
T19464 | N6,N6-Dimethyladenosine | Nucleoside Antimetabolite/Analog | |
N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA. | |||
T4045 | Epetraborole hydrochloride | GSK2251052 hydrochloride | Antibacterial |
Epetraborole hydrochloride (GSK2251052 hydrochloride) is a potent and selective leucyl-tRNA synthetase inhibitor. | |||
T50026 | Aquacycline | HSV | |
Oxytetracycline (OTC) is a broad-spectrum antibiotic that acts by inhibiting protein synthesis in bacteria. Oxytetracycline prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also po... | |||
T20121 | L-Albizziin | NSC-132089,L-beta-Ureidoalanine,L-Albizziine,Albizzine,NSC 132089,Albizziin | Glutaminase |
L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor. | |||
T3052 | Sancycline | Bonomycin,Norcycline,Sancyclinum,6-Demethyl-6-deoxytetracycline | Antibacterial |
Sancycline (Bonomycin) is a rare semi-synthetic tetracycline, acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site. | |||
T1569 | Tigecycline | GAR-936 | ribosome , Antibacterial , Antibiotic , Autophagy |
Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome co... | |||
T8785 | HALOFUGINONE LACTATE | DNA/RNA Synthesis , TGF-beta/Smad | |
HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner ... | |||
TNU0130 | 2'-O-Methyl-2-thiouridine | Nucleoside Antimetabolite/Analog | |
2'-O-Methyl-2-thiouridine is a purine nucleoside analogue present in synthetic thermophilic bacterial tRNAs. 2'-O-Methyl-2-thiouridine is more selective for A than unmodified U. | |||
T8404 | Kasugamycin hydrochloride hydrate | Ksg (hydrochloride hydrate) | Antibacterial , Antibiotic |
Kasugamycin hydrochloride hydrate (Ksg (hydrochloride hydrate))(Ksg) specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs. Ksg inhibition is thought to occur by direct competitio... | |||
T31932 | GJ071 oxalate | GJ 071,GJ-071,GJ071 | Others |
GJ071 oxalate is a Nonsense suppressor. Nonsense suppressors (NonSups) induce “readthrough”, i.e., the selection of near cognate tRNAs at premature termination codons and insertion of the corresponding amino acid into na... | |||
T22774L | Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) | Others | |
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub... | |||
T11920 | LysRs-IN-2 | Others | |
LysRs-IN-2 is a lysyl-tRNA synthetase (KRS) inhibitor with IC50s of 0.13 μM and 0.015 μM for Cryptosporidium parvum lysyl-tRNA synthetase (CpKRS) and Plasmodium falciparum lysyl-tRNA synthetase (PfKRS), respectively. | |||
T11403L | Gln-AMS TFA (209543-57-7 free base) | Gln-AMS TFA | Others |
Gln-AMS(TFA) inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 μM. Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor. | |||
T26001 | Pulvomycin | Antibiotic 1063Z | |
Pulvomycin is a protein biosynthesis inhibitor preventing ternary complex formation between elongation factor Tu, GTP, and aminoacyl-tRNA. | |||
T64165 | Gln-AMS TFA | ||
Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase. | |||
T26178 | SB-217452 | SB217452 | |
SB-217452 is a potent seryl tRNA synthetase inhibitor isolated from Streptomyces. | |||
T11403 | Gln-AMS | Others | |
Gln-AMS is an inhibitor of aminoacyl-tRNA synthetases (AARS). It specifically binds to the A-domain located within the NRPS enzymes. | |||
T72349 | Antibacterial agent 91 | ||
Antibacterial agent 91 is a triple-site aminoacyl-tRNA synthetase (aaRS) inhibitor with an IC 50 of 2.10 μM against Salmonella enterica threonyl-tRNA synthetase ( Se ThrRS) . Antibacterial agent 91 exhibits antibacteri... | |||
T72350 | Antibacterial agent 92 | ||
Antibacterial agent 92 is a triple-site aminoacyl-tRNA synthetase (aaRS) inhibitor with an IC 50 of 0.58 μM against Salmonella enterica threonyl-tRNA synthetase ( Se ThrRS) . Antibacterial agent 92 exhibits antibacteri... | |||
T33511 | Ms2i6A | ms2i6-2-6,ms2i6 2 6 | |
ms2i6A is a mitochondrial tRNA-specific modification, which regulates efficient mitochondrial translation and energy metabolism in mammals. | |||
T11434 | GlyRS-IN-1 | Others | |
GlyRS-IN-1 is an inhibitor of glycyl-tRNA synthase (GlyRS). It can inhibit the growth of bacteria. | |||
T69800 | T-3861174 | ||
T-3861174 is a prolyl tRNA synthetase (PRS) inhibitor, exhibiting significant in vitro anti-tumor activity with GCN2-ATF4 pathway activation. | |||
T21052 | Lysidine | 2-Methyl-2-iMidazoline | Nucleoside Antimetabolite/Analog |
Lysidine (2-Methyl-2-iMidazoline) is a nucleoside rarely seen outside of tRNA. Lysidine has better translation fidelity. | |||
T60974 | MetRS-IN-1 | ||
MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1]. | |||
T40561 | ThrRS-IN-2 | ||
ThrRS-IN-2 is a threonyl-tRNA synthetase (ThrRS) inhibitor with an IC 50 value of 56.5 ± 3.5 μM. | |||
T27088 | CRS-3123 | REP-3123,REP 3123,CRS 3123 | |
CRS-3123, a methionyl-tRNA synthetase inhibitor, is used potentially for the treatment of enteric infections. | |||
T71168 | Epetraborole R-Mandelate | ||
Epetraborole R-Mandelate is a potent and selective leucyl-tRNA synthetase inhibitor. | |||
T11497 | Ganfeborole HCl | GSK3036656 HCl,GSK656 HCl | Antibacterial |
Ganfeborole HCl (GSK3036656 HCl) is a small molecule compound with anti-tuberculosis activity and is an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS; IC50: 0.2 μM). | |||
T10386 | Asp-AMS | Others | |
Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor. | |||
T69741 | DWN-12088 HCl | ||
DWN-12088 HCl is the salt form of DWN-12088 Free Base, an orally administered small molecule prolyl-tRNA synthetase (PRS) inhibitor | |||
T30311 | Bederocin | REP 8839,REP-8839,REP8839 | Antibacterial |
Bederocin (REP8839)is a novel inhibitor of methionyl tRNA synthase (METS) with potent antibacterial activity against clinical isolates of Staphylococcus aureus, Streptococcus pyogenes, and other clinically important Gram... | |||
T26314 | Valyl-ochratoxin A | ||
Valyl-ochratoxin A is a phenylalanyl moiety of ochratoxin A replaced by valine. It is a yeast valyl-tRNA synthetase inhibitor. | |||
T61676 | 4-Piperidinecarboxamide | ||
4-Piperidinecarboxamide is a mycobacterial aspartyl-tRNA synthetase (AspS) inhibitor and a potential anti-tuberculosis (TB) agent [1]. | |||
T72303 | Antibacterial agent 124 | ||
Antibacterial agent 124 is a potent bacterial prolyl-tRNA synthetase (ProRS) inhibitor with an IC 50 of 0.18 μM against Staphylococcus aureus ProRS ( Sa ProRS) . | |||
T63376 | CB 168 | ||
CB 168 is a potent selective aminoacylaminoaryl tetrazole inhibitor targeting isoleucine tRNA synthetase (IleRS). | |||
T60405 | GSK-3036656 free base | GSK656 HCl,GSK 3036656,GSK656,GSK-3036656,GSK-656,GSK 656 | |
GSK656 (GSK3036656) shows potent inhibition of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS) (IC50 = 0.20 μM) which has potential for the treatment of tuberculosis [1]. | |||
T73123 | ThrRS-IN-3 | ||
ThrRS-IN-3 is a highly potent threonyl-tRNA synthetase (ThrRS) inhibitor, with an IC 50 value of 19 nM and a K d of 34 nM for Salmonella enterica ThrRS. ThrRS-IN-3 has antibacterial activities . | |||
T18863 | UAA crosslinker 1 hydrochloride | Others | |
UAA crosslinker 1 hydrochloride is an amber codon used to incorporate non-canonical amino acids (ncAAs) into proteins in vivo. This is achieved by leveraging the promiscuous activity of specific wildtype and engineered a... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0895 | Oxytetracycline | Terramycin | ribosome , Endogenous Metabolite , Antibacterial , Antibiotic , HSV |
Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions. | |||
T6624 | Oxytetracycline Dihydrate | Terramycin Dihydrate | Others , Endogenous Metabolite , Antibacterial , Antibiotic , HSV |
Oxytetracycline Dihydrate (Terramycin Dihydrate) is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. | |||
T0788 | Spectinomycin dihydrochloride | Spectinomycin 2HCl,Actinospectacin | ribosome , Antibacterial , Antibiotic |
Spectinomycin dihydrochloride (Actinospectacin) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea. | |||
T21430 | Oxytetracycline Hydrochloride | Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin | Antiviral , Endogenous Metabolite , Antibacterial , HSV |
Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resultin... | |||
T6856 | Halofuginone | Tempostatin,empostatin,RU-19110 | Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal. | |||
T3524 | Halofuginone hydrobromide | Tempostatin,RU-19110 (hydrobromide),Stenorol | Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce... | |||
T7514 | N2-Methylguanosine | Nucleoside Antimetabolite/Analog , Endogenous Metabolite | |
N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's | |||
T19083 | 1-Methylinosine | N1-Methylinosine,Inosine, 1-methyl | Nucleoside Antimetabolite/Analog , Endogenous Metabolite |
1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite. | |||
T19146 | 5,6-Dihydrouridine | Endogenous Metabolite | |
5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Eukaryota, Bacteria, and some Archaea. | |||
T0912L | Tetracycline | Deschlorobiomycin,Tetracyclinum,Tetracyclin | Others , ribosome , Antibacterial , Antibiotic |
Tetracycline (Tetracyclin) is a naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis. | |||
TN7106 | 2′-O-Methyluridine | Others | |
2′-O-Methyluridine is a natural product that found in RNA such as rRNA, snRNA, snoRNA and tRNA in Archaea, Bacteria, and Eukaryota. | |||
T4456 | N4-Acetylcytidine | N-Acetylcytidine | Others , Endogenous Metabolite |
N4-Acetylcytidine (N-Acetylcytidine) is a modified nucleoside. N4-acetylcytidine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary nucleosides are biological mark... | |||
T6447 | Clindamycin | Clinimycin,Sobelin,Chlolincocin | Antibacterial , Antibiotic |
Clindamycin (Sobelin) dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. Clindamycin is a semisynthetic broad-spectrum antibiotic produced by chemical modification of t... | |||
T5055 | For-Met-OH | fMet,N-Formyl-L-methionine | Others , Endogenous Metabolite |
For-Met-OH (N-Formyl-L-methionine) is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formyl methionyl tRNA. This process occurs in Escherichia coli and other ... | |||
T6599 | N6-methyladenosine | N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A | Others , Influenza Virus , Endogenous Metabolite |
N6-methyladenosine (NSC-29409) is a methylated adenine residue. N6-Methyladenosine is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA); urinary nucleosides are biological ma... | |||
T0912 | Tetracycline hydrochloride | NCI-c55561,Tetracycline HCl | ribosome , Antibacterial , Antibiotic |
Tetracycline hydrochloride (NCI-c55561) is the hydrochloride salt of the tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium ... | |||
TL0005 | 3,5-O-Dicaffeoylquinic acid | Isochlorogenic Acid A,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid | Others |
3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) is an isolated compound from Artemisia argyi; its ester derivatives exert anti-leucyl-tRNA synthetase of Giardia lamblia (GlLeuRS) and potential anti-giardial effects. ... | |||
TQ0193 | N2,N2-Dimethylguanosine | Endogenous Metabolite | |
N2,N2-Dimethylguanosine is an urinary nucleoside. The mean levels of urinary N2,N2-Dimethylguanosine in patients with colorectal cancer are significantly higher than those in patients with intestinal villous adenoma or h... | |||
T1304 | Chlortetracycline hydrochloride | Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride | ribosome , Antibacterial , Antibiotic |
Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride (Isphamycin) is bacteriostatic and inhibits bacterial protein synthesis by b... | |||
T2762 | Kasugamycin hydrochloride | Kasumin | Antibacterial , Antibiotic , Antifungal |
Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydr... | |||
T10582 | Borrelidin | Treponemycin | Others |
Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor. It is a macrolide antibiotic isolated from Streptomyces rochei. | |||
T34765 | T6A | N-(6-Nebularinylcarbamoyl)threonine,t 6 A,t-6-A,t(6)A,N6-Threonylcarbamoyladenosine | Others |
T6A (N6-Threonylcarbamoyladenosine) is a ubiquitously conserved nucleoside, which is essential for modification. T6A is found in the tRNA responsible for transporting the ANN codon. | |||
T13304 | Virginiamycin S1 | Others | |
Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05305 | Alanyl-tRNA synthetase Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Alanyl-tRNA synthetase (AARS) belongs to the family of ligases, specifically those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. This enzyme participates in alanine and aspartate metabolism and ami... | |||
TMPY-02441 | Alanyl-tRNA synthetase Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Alanyl-tRNA synthetase (AARS) belongs to the family of ligases, specifically those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. This enzyme participates in alanine and aspartate metabolism and ami... | |||
TMPY-01461 | EMAP-II/AIMP1 Protein, Human, Recombinant (His) | Human | E. coli |
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, also known as Multisynthase complex auxiliary component p43, Endothelial monocyte-activating polypeptide II, AIMP1, EMAP2 and SCYE1, is a nucleus pro... | |||
TMPJ-01122 | KARS Protein, Human, Recombinant (His) | Human | Human Cells |
Lysine-tRNA ligase, also known as Lysyl-tRNA synthetase, LysRS, KARS and KIAA0070, belongs to the class-II aminoacyl-tRNA synthetase family. The N-terminal cytoplasmic domain (1-65) is a functional tRNA-binding domain, w... | |||
TMPY-03393 | DARS Protein, Human, Recombinant (His) | Human | E. coli |
Aspartate tRNA ligase 1, also known as DARS, is part of a multienzyme complex of aminoacyl-tRNA synthetases. It belongs to the class-II aminoacyl-tRNA synthetase family. DARS charges its cognate tRNA with aspartate durin... | |||
TMPY-05413 | HARS/HisRS Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
TMPH-00313 | tRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) | Brugia malayi | E. coli |
TMPY-03753 | WARS Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
WARS, also known as TrpRS, is an aminoacyl-tRNA synthetase that belongs to the class-I aminoacyl-tRNA synthetase family. There are two forms of tryptophanyl-tRNA synthetase: a cytoplasmic form, named WARS, and a mitochon... | |||
TMPY-03448 | AARSD1 Protein, Human, Recombinant (His) | Human | E. coli |
AARSD1 belongs to the class-II aminoacyl-tRNA synthetase family, Alax-L subfamily. AARSD1 binds 1 zinc ion per subunit functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). Four transcri... | |||
TMPY-01306 | DNMT2 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evo... | |||
TMPJ-01241 | DTD1 Protein, Human, Recombinant (His) | Human | Human Cells |
D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is... | |||
TMPY-03572 | PTRH2 Protein, Human, Recombinant (His) | Human | E. coli |
PTH2, also known as PTRH2, is a mitochondrial protein that belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs whic... | |||
TMPY-03015 | EMAP-II/AIMP1 Protein, Mouse, Recombinant | Mouse | E. coli |
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, also known as Multisynthase complex auxiliary component p43, Endothelial monocyte-activating polypeptide II, AIMP1, EMAP2 and SCYE1, is a nucleus pro... | |||
TMPH-01631 | DCP2 Protein, Human, Recombinant (His) | Human | E. coli |
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | |||
TMPH-01630 | LOXL3 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | |||
TMPH-01407 | Glypican 1/GPC1 Protein, Human, Recombinant (GST & His & Myc) | Human | E. coli |
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. | |||
TMPH-03712 | Clp1 Protein, Xenopus laevis, Recombinant (His) | Xenopus laevis | E. coli |
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated mo... | |||
TMPY-03976 | EEF1E1 Protein, Human, Recombinant (His) | Human | E. coli |
EEF1E1, also known as AIMP3 and p18, is a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, EEF1E1 is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex... | |||
TMPH-02875 | ROMO1 Protein, Mouse, Recombinant (His) | Mouse | in vitro E. coli expression system |
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP s... | |||
TMPH-00732 | RtcB Protein, E. coli, Recombinant (His) | E. coli | Yeast |
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | |||
TMPH-02044 | RHOG Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). | |||
TMPY-04108 | EIF5A Protein, Human, Recombinant (His) | Human | E. coli |
EIF-5A, also known as EIF5, functions in start site selection as a GTPase accelerating protein (GAP) for the eukaryotic translation initiation factor (eIF) 2•GTP•tRNA ternary complex within the ribosome-bound pre-initiat... | |||
TMPH-01166 | CGAS Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly form... | |||
TMPY-03184 | EIF5 Protein, Human, Recombinant (GST) | Human | E. coli |
EIF-5A, also known as EIF5, functions in start site selection as a GTPase accelerating protein (GAP) for the eukaryotic translation initiation factor (eIF) 2•GTP•tRNA ternary complex within the ribosome-bound pre-initiat... | |||
TMPH-02256 | Trypsin-3 Protein, Human, Recombinant (His) | Human | E. coli |
Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S... | |||
TMPH-00519 | StxB Protein, Enterobacteria phage H19B, Recombinant (His) | Enterobacteria phage H19B | E. coli |
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, where it has be... | |||
TMPH-00019 | BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO) | Acinetobacter baumannii | E. coli |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. | |||
TMPH-02214 | Tomoregulin-1 Protein, Human, Recombinant (His) | Human | HEK293 |
Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. | |||
TMPH-03461 | IFM1 Protein, S. cerevisiae, Recombinant (GST) | Saccharomyces cerevisiae | E. coli |
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis o... | |||
TMPH-03742 | EEF1A1 Protein, Cricetulus griseus, Recombinant (His) | Chinese hamster | E. coli |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF... | |||
TMPH-03125 | Saposin-B-Val Protein, Pig, Recombinant (Flag & His) | Sus scrofa (Pig) | Yeast |
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis o... | |||
TMPY-01661 | METTL1 Protein, Human, Recombinant (His) | Human | E. coli |
tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein that belongs to the methyltransferase superfamily and TrmB family. M... | |||
TMPH-01541 | ITIH4 Protein, Human, Recombinant (His) | Human | Yeast |
Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylat... | |||
TMPH-02696 | GNAQ Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase acti... | |||
TMPH-01167 | CDK1 Protein, Human, Recombinant (His) | Human | E. coli |
Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochon... | |||
TMPH-01164 | ATF3 Protein, Human, Recombinant (His) | Human | E. coli |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF... | |||
TMPH-00672 | Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His) | E. coli | E. coli |
GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splici... | |||
TMPH-00633 | Heat-stable enterotoxin A2 Protein, E. coli, Recombinant (His & Myc & SUMO) | E. coli | E. coli |
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and sel... | |||
TMPY-02551 | CCDC134 Protein, Human, Recombinant (His) | Human | HEK293 |
Coiled-coil domain containing 134 (CCDC134) is a 229 amino acids secretory protein. Coiled-coil domain is a motif in which alpha-helix are coiled together. It has been found in many types of proteins, including transcrip... | |||
TMPJ-00973 | EIF1AX Protein, Human, Recombinant (His) | Human | E. coli |
Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding of the 43S complex (a 40S... | |||
TMPJ-00763 | ANG Protein, Human, Recombinant | Human | E. coli |
Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular t... | |||
TMPY-03608 | EEF1B2 Protein, Human, Recombinant (His) | Human | E. coli |
EF1B, also known as EEF1B2, is a translation elongation factor. It belongs to the EF-1-beta/EF-1-delta family. Elongation factors are a set of proteins that are used in protein synthesis in the cell. In the ribosome, the... | |||
TMPH-02885 | SOSTDC1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2. Hydrolyzes adenosin... |