tetrazine-ph-peg-4-ph-aldehyde

5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.

PDP-C1-Ph-Val-Cit is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle at low cytotoxicity, blocks mitosis in Vero cells, affects the size of M-MSV-induced tumors, and influences the immune response by inhibiting PHA-induced proliferation of T lymphocytes.

Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC Linker which is used for the EED-targeted PROTAC[1].

Mal-Ph-CONH-PEG4-NHS ester, a non-cleavable four-unit polyethylene glycol (PEG) ADC linker, plays a crucial role in the synthesis of antibody-drug conjugates (ADCs).

Val-Cit-PAB-MMAE is a molecular entity designed to function as an antibody-drug conjugate (ADC) or as a component of bispecific antigen-binding molecules, specifically targeting the hepatocyte growth factor receptor known as c-Met (MET).

Ald-Ph-NHS ester is a non-cleavable linker used in antibody-drug-conjugation (ADC).

(S,R,S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) serves as an E3 ligase ligand-linker conjugate, integrating a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is utilized in PROTAC EED degrader-1, a PROTAC that targets EED with a potency (pKD) of 9.02[1].

Ald-Ph-amido-PEG2 is a noncleavable ADC linker for antibody-drug conjugate[1].

Ald-Ph-amido-PEG11-C2-NH2 is an 11-unit polyethylene glycol (PEG) linker that is non-cleavable. It is specifically designed for use in the synthesis of antibody-drug conjugates (ADCs).

Ald-Ph-amido-PEG11-NH-Boc is a non-cleavable 11-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs).

Ald-Ph-PEG4-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG2-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Tetrazine-Ph-PEG4-Ph-aldehyde is a polyethylene glycol (PEG) derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable linker employed in ADC synthesis for conjugation with antibodies, ultimately producing antibody-drug conjugates (ADCs).

NHS-SS-Ph, a cleavable linker utilized in antibody-drug conjugate (ADC) synthesis, facilitates the release of therapeutic agents under specific intracellular conditions [1].

Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker commonly employed for synthesizing PROTACs[1].

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is an E3 ligase ligand-linker conjugate, specifically designed for targeting the EED protein in PROTAC applications[1].

Ald-Ph-amido-PEG3-C1-Boc is a polyethylene glycol (PEG) linker specific to antibody-drug conjugates (ADC).

Ald-Ph-PEG24-TFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG23-OPSS is a cleavable 23-unit polyethylene glycol linker commonly employed for the synthesis of antibody-drug conjugates (ADCs)[1].

Ald-Ph-amido-C2-PEG2-amine is a polyethylene glycol (PEG)-based linker utilized for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1].

Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist. It is also suitable for development as a potential treatment for T2DM.

Ald-Ph-amido-PEG2-C2-Boc is a polyethylene glycol (PEG)-based linker utilized for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Mal-NO2-Ph-PEG12-NHS is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Tetrazine-Ph-NHCO-PEG4-NH-Boc is a PEGylated PROTAC linker suitable for PROTAC synthesis[1].

5-Ph-IAA-AM is an analog of 5-Ph-IAA which is eggshell-permeable. 5-Ph-IAA-AM enhanced protein degradation in laid embryos. 5-Ph-IAA-AM can be used to reveal the roles of proteins in C. elegans, particularly those temporally controlled protein degradation that involved in embryogenesis and development [1].

Ald-Ph-amido-PEG2-C2-Pfp ester is a non-cleavable 2-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.

Pip-alkyne-Ph-COOCH3 is an alkyl-chain based PROTAC linker utilized for the synthesis of PROTAC ARD-266[1].

N3-Ph-NHS ester is a noncleavable ADC linker. N3-Ph-NHS ester can be used in the synthesis of antibody-drug conjugates (ADCs).

Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker utilized in the development of antibody-drug conjugates (ADC).

Ald-Ph-amido-PEG1-C2-Pfp ester is a non-cleavable 1-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.

AZD-CO-C2-Ph-amido-Ph-azide is an alkyl chain-derived PROTAC linker suitable for PROTACs synthesis[1].

Ald-Ph-amido-C2-PEG3-NH-Boc is a polyethylene glycol (PEG)-based bifunctional linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Dox-Ph-PEG1-Cl, also referred to as PROTAC Linker 34, is a PEG-based compound employed for the synthesis of PROTACs[1].

Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker utilized in the formation of antibody-drug conjugates (ADCs).

Tetrazine-Ph-PEG5-NHS ester is a PEGylated N-hydroxysuccinimide (NHS) ester molecule that serves as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Ph CL 28A is a 15-hydroxyprostaglandin dehydrogenase inhibitor.

Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-derived linker for PROTACs synthesis.

Ph-HTBA, a high-affinity, brain-penetrating modulator for CaMKIIα, exhibits a binding affinity with a Kd value of 757 nM. It holds potential for use in research related to ischemia and neurodegenerative disorders.

m-PEG2-O-Ph-3-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Tetrazine-Ph-NHCO-PEG6-NH-Boc is a PEG-based PROTAC linker utilized for PROTACs synthesis[1].

Ald-Ph-PEG2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride is a chemical compound that features a cereblon (CRBN) ligand, functioning as an E3 ubiquitin ligase, along with a linker. It can be utilized to create the PROTAC MD-224[1].

Tetrazine-Ph-NHCO-PEG4-alkyne is a PEG4-based linker for PROTACs synthesis[1].

Tetrazine-Ph-OPSS is an ADC linker employed for synthesizing ADCs, or antibody-drug conjugates [1].

NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based compound utilized for the synthesis of PROTACs. [1]

Ald-Ph-amido-PEG4-propargyl is a non-cleavable 4-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker employed in ADC synthesis[1].

AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker, commonly employed in the synthesis of antibody-siRNA conjugates.