Search Result

Search Results for " thp-1 "

Compounds

Natural Products

1732

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T9552	BAZ1A-IN-1		Epigenetic Reader Domain
	BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-survival activity against cancer cell lines with high BAZ1A expression, but weak or no activity ag...		Epigenetic Reader Domain
T38705	MS-PEG1-THP	MS-PEG1-THP
	MS-PEG1-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system withi...
T11492	GSK2983559 free acid		Others , RIP kinase
	GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammato...		Others , RIP kinase
T38576	Propargyl-PEG1-THP	Propargyl-PEG1-THP
	Propargyl-PEG1-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome syste...
T17089	THP-SS-PEG1-Tos		Others
	THP-SS-PEG1-Tos is a 1 unit PEG ADC linker that is cleavable. It is employed during the synthesis of antibody-drug conjugates (ADCs)[1].		Others
T3278	Piribedil	EU-4200,Trivastan,ET-495,Trivastal	Dopamine Receptor , Histone Methyltransferase , Adrenergic Receptor
	Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
T10384	Farudodstat	ASLAN003	Apoptosis , Dehydrogenase , DNA/RNA Synthesis
	Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML.		Apoptosis , Dehydrogenase , DNA/RNA Synthesis
T9016	AI-10-47	1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47	Others
	AI-10-47 (1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47) is a small molecule inhibitor of CBFβ-RUNX binding(IC50 : 3.2 μM).		Others
T28178	NLRP3-IN-9	INF-4E,INF 4E,INF4E	NOD
	NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- ...		NOD
T17088	THP-SS-PEG1-Boc		Others
	THP-SS-PEG1-Boc is a cleavable ADC linker comprising a one-unit PEG, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].		Others
T60012	HS-243		IRAK , MAPK , CDK
	HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.		IRAK , MAPK , CDK
T6019	Volasertib	BI 6727	Apoptosis , PLK
	Volasertib (BI 6727) (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis. It also inhibits PLK2/PLK3 (IC50s: 5/56 nM).		Apoptosis , PLK
T7162	R1487 Hydrochloride	R1487 (Hydrochloride)	p38 MAPK , Autophagy
	R1487 Hydrochloride (R1487 (Hydrochloride)) is an orally bioavailable and highly selective inhibitors of p38α.		p38 MAPK , Autophagy
T28072L	MLN-3897 TFA	MLN-3897 TFA(1010731-97-1 Free base)	CCR
	MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.		CCR
T9645	CU-115	N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide	TLR
	CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively. CU-115 decreases production of TNF-α and IL-1β activated by R-848 in THP-1 cells.		TLR
T3502	C29		TLR
	C29 is a novel inhibitor of TLR2/1 and TLR2/6 signaling induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages.		TLR
T63140	LSD1-IN-20		Histone Demethylase
	Lsd1-in-20 is a potent dual inhibitor of LSD1/G9a with Ki values of 0.44 and 0.68 μM, respectively. LSD1-IN-20 showed antiproliferative activity against THP-1 leukemia cells and MDA-MB-231 breast cancer cells in vitro, w...		Histone Demethylase
T4062	CAY10602		Sirtuin
	CAY10602 is a SIRT1 activator. CAY10602 was derived from high throughput screening for compounds that increase SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays show that CAY10602 dose-depende...		Sirtuin
T36527	IL-4-inhibitor-1		IL Receptor
	IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM). It is selective for IL-4 over IL-13 (EC50= 18.2 μM). IL-4 inhib...		IL Receptor
T60442	NLRP3/AIM2-IN-3		NOD , AIM2
	NLRP3/AIM2-IN-3 is a unique molecule that inhibits NLRP3 and AIM2 inflammasome activation in a species-specific manner. It has an IC50 value for cell lysis of 0.077 ± 0.008 μ M. NLRP3/AIM2-IN-3 is a potent inhibitor of N...		NOD , AIM2
T1764	Adezmapimod	PB 203580,RWJ 64809,SB203580	Mitophagy , p38 MAPK , Autophagy
	Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive. Adezmapimod possesses autophagy and mitochondrial autophagy activating activity. Adezmapimod displays more than 100...		Mitophagy , p38 MAPK , Autophagy
T18847	THP-PEG4-Pyrrolidine(N-Me)-CH2OH		Others
	THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, facilitates the synthesis of PROTAC K-Ras Degrader-1[1].		Others
T19854	Evoxine
	Evoxine is a selective inhibitor of CO2-induced immune suppression. It inhibits hypercapnic suppression of interleukin-6 and the chemokine CCL2 expression in human THP-1 macrophages.
T14909	CCX140	CCX140-B	CCR
	CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.		CCR
T17087	THP-SS-alcohol		Others
	THP-SS-alcohol is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].		Others
T38328	CU-32
	CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS ...
T68813	NSC-18725
	NSC-18725 is a novel inhibitor of growth of intracellular Mycobacterium tuberculosis, inducing autophagy in differentiated THP-1 macrophages.
T18853	Tos-PEG4-THP		Others
	Tos-PEG4-THP is a polyethylene glycol (PEG) derivative utilized as a linker in the synthesis of PROTAC K-Ras Degrader-1, a potential therapeutic compound for targeted degradation of K-Ras protein [1].		Others
T74718	STING modulator-5
	STING modulator-5 (compound 38), a STING modulator, exhibits a pIC50 value of 9.5 and antagonizes peripheral blood mononuclear cells (PBMC) with a pIC50 value of 8.1. Additionally, it acts as an antagonist of THP-1 cells...
T72614	STING modulator-3
	STING modulator-3 is a STING inhibitor that effectively inhibits R232 STING, exhibiting a Ki value of 43.1 nM in scintillation proximity assays. Despite its inhibitory action on R232 STING, it does not affect IRF-3 activ...
T38329	CU-76
	CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sens...
T62659	Cathepsin C-IN-4
	Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).
T72615	STING modulator-4
	STING Modulator-4 is a competitive modulator of STING, exhibiting a K_i value of 0.0933 μM for the R232H STING variant. It demonstrates an EC_50 of over 10 μM for p-IRF3 activation in THP-1 cells.
T18846	THP-PEG4-Pyrrolidine(N-Boc)-CH2OH		Others
	THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a polyethylene glycol (PEG) based PROteolysis TArgeting Chimera (PROTAC) linker, employed for the synthesis of PROTAC K-Ras Degrader-1, as documented in reference [1].		Others
T83901	BDW568
	BDW568, a prodrug of BDW-OH, serves as a stimulator of interferon genes (STING) agonist. This compound effectively induces STING transcriptional activity, evidenced by a reporter assay in THP-1 cells, with an EC50 value ...
T61405	LSD1-IN-14
	LSD1-IN-14, a powerful and specific inhibitor of LSD1 (with an IC50 value of 0.89 μM), effectively suppresses the growth of A549 and THP-1 cells and promotes the apoptosis of tumor cells [1].
T16614	Propargyl-PEG4-acid		Others
	Propargyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-IAP PROTACs Ibrutinib -based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells[1]...		Others
T63854	Cathepsin C-IN-3
	Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).
T78068	O-allylvanillin		Others
	O-Allylvanillin, an O-allylchalcone derivative, exhibits anti-cancer properties by inhibiting the growth of THP-1, HL60, Hep-G2, and MCF-7 cells with IC50 values of 74.76 μM, 63.52 μM, 90.99 μM, and 90.11 μM, respectivel...		Others
T28269	ORY-1001 free base	RG 6016,ORY-1001,ORY 1001,ORY1001,RG-6016,RG6016
	ORY-1001 is a KDM1A inhibitor (IC50 <20nM) with high selectivity against related FAD dependent aminoxidases (MAO-A/B, IL4I1, KDM1B >100uM, SMOX 7uM). Treatment of THP-1 (MLL-AF9) cells with ORY-1001, results in a time/do...
T17084	THP-PEG6-OH		Others
	THP-PEG6-OH is a polyethylene glycol (PEG)-based PROTAC linker, utilized in the synthesis of PROTACs[1]. It is also a non-cleavable three-unit PEG linker for antibody-drug conjugates (ADCs)[2].		Others
T62950	IRAK4-IN-18
	IRAK4-IN-18 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 15 nM). IRAK4-IN-18 inhibits LPS-induced IL23 production in THP and DC cells and blocks the development of arthritis in rats,...
T35701	FSL-1 TFA
	FSL-1 TFA, a toll-like receptor 2/6 (TLR2/6) agonist derived from bacteria, bolsters resistance against experimental HSV-2 infection[1] and stimulates MMP-9 production via the TLR2 and NF-κB/AP-1 signaling pathways in mo...
T83775	STING Agonist 12L	Stimulator of Interferon Genes Agonist 12L
	STING agonist 12L is a stimulator of interferon genes (STING) agonist that exhibits binding affinity for both wild-type STING and its variants R232, AQ, and Q with half-maximal inhibitory concentrations (IC50s) of 1.15 µ...
T9655	NBC 6
	NLRP3-IN-NBC6 is a potent, selective NLRP3 inflammasome inhibitor with IC50 of 574 nM. NLRP3-IN-NBC6 acts independently of Ca 2+. NLRP3-IN-NBC6 inhibits Nigericin -induced inflammasome activation in THP-1 cells and Imiqu...
T63139	Glutaminyl cyclases-IN-1
	Glutaminyl cyclases-IN-1 (IsoQC-IN-1) is a potent inhibitor of Glutaminyl cyclases (QC), which acts on human QC (IC50: 12 nM) and isoQC (IC 50:73 nM). Glutaminyl cyclases-IN-1 inhibited isoQC and selectively blocked CD47...
T79352	RIPK2/3-IN-1		RIP kinase
	RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3. Additionally, in a 14-TriLAN-Gly/NOD1 THP-1 cell-based NF-κB reporter assay, RIPK2/3-IN-1...		RIP kinase
T61945	HGGPPS-IN-1
	HGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). HGGPPS-IN-1 has an effective inhibitory effect on human geranyl geranyl pyrophosphate synthase (hGGPPS). HGGPPS-IN-1 can ...
T63088	NOD2 antagonist 1
	NOD2 antagonist 1 (compound 32) is an effective and selective NOD2 antagonist (IC50: 5.23μM). NOD2 antagonist 1 in THP-1 cells repress Muramyl DiDP (MDP) -induced IL-8 secretion. NOD2 antagonist 1 in PBMCs cells inhibits...
T28072	MLN-3897	AVE9897,AVE 9897,CCR1 antagonist 10,AVE-9897	CCR
	MLN-3897 (CCR1 antagonist 10) is an orally active antagonist of CCR1 with a Ki of 2.3 nM for 125I-MIP-1α binding to THP-1 cell membranes. MLN-3897 inhibits Akt signaling and MM cell survival and proliferation.		CCR

Compounds

BAZ1A-IN-1

T9552

Synonym:

Target: Epigenetic Reader Domain

MS-PEG1-THP

T38705

Synonym: MS-PEG1-THP

Target: Others, RIP kinase

Propargyl-PEG1-THP

T38576

Synonym: Propargyl-PEG1-THP

Synonym: EU-4200,Trivastan,ET-495,Trivastal

Target: Dopamine Receptor, Histone Methyltransferase, Adrenergic Receptor

Farudodstat

T10384

Synonym: ASLAN003

Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis

AI-10-47

T9016

Synonym: 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47

Target: Others

NLRP3-IN-9

T28178

Synonym: INF-4E,INF 4E,INF4E

Target: IRAK, MAPK, CDK

Volasertib

T6019

Synonym: BI 6727

Target: Apoptosis, PLK

R1487 Hydrochloride

T7162

Synonym: R1487 (Hydrochloride)

Target: p38 MAPK, Autophagy

MLN-3897 TFA

T28072L

Synonym: MLN-3897 TFA(1010731-97-1 Free base)

Target: CCR

CU-115

T9645

Synonym: N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide

Target: Histone Demethylase

Synonym: PB 203580,RWJ 64809,SB203580

Target: Mitophagy, p38 MAPK, Autophagy

THP-PEG4-Pyrrolidine(N-Me)-CH2OH

THP-PEG4-Pyrrolidine(N-Boc)-CH2OH

Synonym: RG 6016,ORY-1001,ORY 1001,ORY1001,RG-6016,RG6016

Synonym: Stimulator of Interferon Genes Agonist 12L

Glutaminyl cyclases-IN-1

Synonym: AVE9897,AVE 9897,CCR1 antagonist 10,AVE-9897

Target: CCR

Cat No.	Product Name	Synonyms	Targets
T2P2870	Damascenone	trans-damascenone,Beta-Damascenone	Others , NF-κB , Endogenous Metabolite
	Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.		Others , NF-κB , Endogenous Metabolite
T9218	Andrograpanin	19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE	p38 MAPK
	Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.		p38 MAPK
TN1879	Lucideric acid A	Lucidenic acid A	MMP , p38 MAPK , JNK
	Lucideric acid A (Lucidenic acid A) is a modulator of JNK and p38 and enhances LPS-induced immune responses in monocytic THP-1 cells possibly via the modulation of p38 and JNK/MAPKs activation.		MMP , p38 MAPK , JNK
T81159	Sibiricine
	Sibiricine (Compound 8), an isoquinoline alkaloid extracted from the medicinal plant Corydalis crispa, exhibits substantial anti-inflammatory effects by inhibiting TNF-α production in LPS-activated THP-1 cells [1].
TN5593	Euphohelioscopin A
	Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it ex...
TN5238	Viscidulin II		IL Receptor , TNF
	Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of ...		IL Receptor , TNF
T37442	Aspergillin PZ
	Aspergillin PZ is a fungal metabolite originally isolated from A. awamori. It induces morphological deformation of P. oryzae conidia when used at a concentration of 89 nM. Aspergillin PZ is active against S. epidermidis ...
T72742	(-)-Pinocembrin
	(-)-Pinocembrin demonstrates anti-mycobacterial activity against Mycobacterium tuberculosis H37Ra, presenting IC 50 values of 1.11 mg/mL in the dormant phase and 1.21 mg/mL in the active phase. Additionally, this compoun...
T37751	Streptazolin
	Streptazolin is a fungal metabolite originally isolated from S. viridochromogenes. It increases NF-κB activity when used at concentrations ranging from 60 to 130 μg/ml, at least in part, via PI3K signaling. Streptazolin ...
TN3395	Alpinone 3-acetate		IFNAR
	Alpinone 3-acetate showed anti-inflammatory effects and inhibited the inflammatory response in mouse ear edema models induced by 12-O-tetradecanophenol 13-acetate. Alpinone 3-acetate is a derivative of Alpinone. Alpinone...		IFNAR

Natural Products

Damascenone

T2P2870

Synonym: trans-damascenone,Beta-Damascenone

Target: Others, NF-κB, Endogenous Metabolite

Andrograpanin

T9218

Synonym: 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE

Target: p38 MAPK

Lucideric acid A

TN1879

Synonym: Lucidenic acid A

Target: MMP, p38 MAPK, JNK

Target: IL Receptor, TNF

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-00807	Osteopontin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration ...
TMPK-01079	PLD4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. fu...
TMPK-01138	PLD4 Protein, Human, Recombinant (His)	Human	HEK293
	Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. fu...
TMPY-03278	SMPDL3A Protein, Human, Recombinant (His)	Human	HEK293
	SMPDL3A gene is a novel liver X receptor (LXR) -regulated gene, with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observe...
TMPY-04512	SMPDL3A Protein, Mouse, Recombinant (His)	Mouse	HEK293
	SMPDL3A gene is a novel liver X receptor (LXR) -regulated gene, with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observe...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells

TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant	Human	HEK293

TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)	Human	HEK293

TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-01281	ACVR2B Protein, Mouse, Recombinant (His)	Mouse	HEK293
	ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-01949	CD19 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-01386	CD155/PVR Protein, Human, Recombinant (His)	Human	HEK293
	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-04493	BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-01055	IL-4R Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-03524	B7-H4 Protein, Human, Recombinant (His)	Human	HEK293
	V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express...
TMPY-01834	CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)	Mouse	HEK293
	Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional...
TMPY-03256	NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)	Human	Baculovirus-Insect Cells
	KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular protei...
TMPY-01247	FLT3 Protein, Human, Recombinant (T227M, His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-05275	CD79B Protein, Human, Recombinant (His)	Human	HEK293

TMPY-00381	PSMA Protein, Human, Recombinant (His)	Human	HEK293
	Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPY-00949	VEGFR3/FLT4 Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His)	Human	HEK293
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-01431	L1CAM Protein, Human, Recombinant (His)	Human	HEK293
	L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai...
TMPY-05357	GCDH Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells

TMPY-00828	Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)	Human	HEK293
	Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfat...
TMPY-04730	LAG-3 Protein, Human, Recombinant (His)	Human	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-01885	Human RSV (B1) glycoprotein G/RSV-G Protein (His)	RSV	HEK293
	Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. It is classified within the genus pneum...
TMPY-01475	Jagged 1 Protein, Human, Recombinant (His)	Human	HEK293
	Protein Jagged 1, also known as JAG1, JAGL1, and CD339, is a single-pass type I membrane protein that contains 1 DSL domain and 15 EGF-like domains. JAG1/Jagged 1 is widely expressed in adult and fetal tissues. The expre...
TMPY-04333	LRRC15 Protein, Human, Recombinant (hFc)	Human	HEK293
	LRRC15 (Leucine-Rich Repeat Containing 15) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The tumor antigen 15-leucine-rich repeat-containing membrane protein (LRRC15) is a transmemb...
TMPY-05306	TRIM21 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells

TMPY-05131	PCSK9 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Proprotein convertase subtilisin/kexin type 9 (PCSK9), also known as NARC1 (neural apoptosis regulated convertase), which is a newly identified human secretory subtilase belonging to the proteinase K subfamily of the sec...
TMPY-01483	SLAMF7 Protein, Human, Recombinant (His)	Human	HEK293
	SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 ...
TMPY-01258	IL-13RA1 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha,...
TMPY-01446	IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti...
TMPY-02170	SCF Protein, Human, Recombinant (aa 1-189, His)	Human	Baculovirus-Insect Cells
	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod...
TMPY-04165	FGFR3 Protein, Human, Recombinant (His)	Human	HEK293
	FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-00277	IL-18 Protein, Human, Recombinant	Human	E. coli
	Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g...
TMPY-03104	FGF-17 Protein, Human, Recombinant	Human	E. coli
	FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including ...
TMPY-02904	TLR4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans...
TMPY-02078	HtrA2/Omi Protein, Human, Recombinant (His)	Human	E. coli
	Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ...
TMPK-00347	Serum Albumin Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands i...
TMPY-02205	Beta-Catenin Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	beta-Catenin, also known as CTNNB1, is a member of the armadillo family of proteins. These proteins have multiple copies of the so-called armadillo repeat domain, which is specialized for protein-protein binding. It is p...
TMPY-00939	Thrombopoietin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a...
TMPY-01126	CD39 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	CD39, also known as ENTPD1, belongs to the GDA1/CD39 NTPase family. It is expressed primarily on activated lymphoid cells and can also be detected in endothelial tissues. The vascular isoform and the placental isoform II...
TMPY-04483	IRAK4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-06247	TGF beta 3 Protein, Human, Recombinant (hFc)	Human	HEK293

TMPY-00853	IL-1RA Protein, Human, Recombinant	Human	E. coli
	Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and mo...
TMPY-06982	IGF1/IGF-I Protein, Human, Recombinant	Human	E. coli
	IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and I...
TMPK-00942	DLK1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neu...
TMPY-01257	UPAR/PLAUR Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ...
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