Search Result

Search Results for " triple "

111

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T9407	Rasarfin		Others , Ras
	Rasarfin inhibits Ras and ARF6.		Others , Ras
T41256	SP-96		Aurora Kinase
	SP-96 is a highly effective and selective inhibitor of Aurora B with an IC50 of 0.316 nM. SP-96 shows selective growth inhibition in NCI60 screening, including MDA-MD-468 (GI50=107 nM). SP-96 can be used in triple negati...		Aurora Kinase
T9468	FR054		Others
	FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect. FR054 induces in different breast cancer cells a dramatic decrease in cell proliferation and su...		Others
T10860	Col003		HSP
	Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM). It can be used for the investigation of fibrosis.		HSP
T13780	MS1943		Apoptosis , Histone Methyltransferase
	MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM).		Apoptosis , Histone Methyltransferase
T13044	Mevociclib	SY-1365	CDK
	Mevociclib (SY-1365) is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.		CDK
T6797	Telaglenastat	CB 839,CB839,CB-839	transporter , Glutaminase , Autophagy
	Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC.		transporter , Glutaminase , Autophagy
T7530	PD146176	NSC168807	Ferroptosis , Lipoxygenase , Autophagy
	PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology...		Ferroptosis , Lipoxygenase , Autophagy
T19664	ON1231320	GBO-006	Apoptosis , PLK
	ON1231320 (GBO-006) is a Polo-like kinase 2 (PLK2) inhibitor.		Apoptosis , PLK
T2655	CEP-37440	CEP37440	FAK , ALK
	CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).		FAK , ALK
T9320	YK-3-237	B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid	Sirtuin
	YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative effects toward triple-negative breast cancer (TNBC) cells ca...		Sirtuin
T8808L	LYN-1604 dihydrochloride	LYN-1604 2HCl（2216753-86-3 free base)	Apoptosis , Autophagy
	LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.		Apoptosis , Autophagy
T4123	LYN-1604	LYN1604	Apoptosis , Autophagy
	LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.		Apoptosis , Autophagy
T35528	TD52		Apoptosis , Phosphatase , Akt
	TD52 is an orally active inhibitor of cancerous inhibitor of PP2A (CIP2A). TD52 is an Erlotinib derivative and indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter.		Apoptosis , Phosphatase , Akt
T34795	Tedatioxetine	Lu AA-24530,Lu AA24530,Lu AA 24530
	Tetaxetine( LU AA24530) has been reported as a triple reuptake inhibitor (5-HT > NE > DA) and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist.Meanwhile, it is an antidepressant agent.
T70353	JG-231		HSP
	JG-231 is a JG-98 analog with anticancer activity.JG-231 inhibits the MDA-MB-231 xenograft tumor model of triple-negative breast cancer (TNBC).JG-231 inhibits the interaction of Hsp70-BAG3.JG-231 inhibits the MDA-MB-231 ...		HSP
T2092	Amitifadine hydrochloride	DOV-21947 hydrochloride,EB-1010 hydrochloride	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
	Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
T6224	Iniparib	NSC-746045,IND-71677,BSI-201	PARP , Influenza Virus
	Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).		PARP , Influenza Virus
T8569	DMH-25		mTOR
	DMH25 is a novel covalent and potent inhibitor of mTOR and shows in vivo antitumor activity against triple-negative breast cancer cells.		mTOR
T9583	HJ-PI01	N-Acetylphenoxazine,10-acetylphenoxazine	Pim
	HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.		Pim
T5001	Nintedanib esylate	Intedanib,BIBF 1120 (esylate),Nintedanib Ethanesulfonate Salt,BIBF 1120	VEGFR , FGFR , PDGFR
	Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β		VEGFR , FGFR , PDGFR
T7296	THZ2	CDK7-IN-1	CDK
	THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).		CDK
T32737	Liafensine	BMS820836,BMS 820836,DB104,BMS-820836	Dopamine Receptor , 5-HT Receptor , Norepinephrine
	Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dopamine for the study of major depressive disorder and centra...		Dopamine Receptor , 5-HT Receptor , Norepinephrine
T3526	Dasotraline hydrochloride	SEP-225289 hydrochloride	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
	Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respe...
T74178	Glembatumumab vedotin	CR011-vcMMAE,CR 011 ADC,CDX-011	Microtubule Associated
	Glembatumumab vedotin (CDX-011) is an antibody-activated small molecule coupling, Glembatumumab vedotin has potent anticancer effects and can be used in the study of triple negative breast cancer (TNBC).		Microtubule Associated
T72528	NSC243928 mesylate		HuR
	NSC243928 mesylate binds to human lymphocyte antigen 6 (LY6), a cell growth inhibitor with anticancer activity, and induces cell death in triple-negative breast cancer cells in a LY6K-dependent manner.		HuR
T14685	BMS-986158		Epigenetic Reader Domain
	BMS-986158 is a highly effective BET inhibitor, demonstrating IC50 values of 6.6 nM in NCI-H211 small cell lung cancer (SCLC) cells and 5 nM in MDA-MB231 triple negative breast cancer (TNBC) cells.		Epigenetic Reader Domain
T8325	SR-4835		Apoptosis , CDK
	SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (TNBC) cells		Apoptosis , CDK
T77759	GPX4-IN-6		GPX
	GPX4-IN-6 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 μM) with antitumour activity.GPX4-IN-6 induces iron death and is used for the treatment= and prevention of triple negative breast cancer (TNBC).		GPX
T77755	GPX4-IN-5		GPX
	GPX4-IN-5 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 μM) with antitumour activity.GPX4-IN-5 induces iron death and can be used for the prevention and treatment of triple-negative breast cancer (TNBC).		GPX
T77342	GSK-3 inhibitor 3		GSK-3 , Microtubule Associated
	GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and GSK-3β with IC50s of 0.35 nM and 0.25 nM, respectively.GSK-3 inhibitor 3 reduces the phosphorylation level of tau ...		GSK-3 , Microtubule Associated
T76279	Retatrutide	LY3437943	Glucagon Receptor
	Retatrutide (LY3437943) is a triple agonist of the glucagon receptor, glucose-dependent insulinotropic polypeptide receptor, and glucagon-like peptide-1 receptor (GLP-1R), and inhibits GCGR, GIPR, and GLP-1R.Retatrutide ...		Glucagon Receptor
T17206	UPGL00004		Others , Glutaminase
	UPGL00004 is a potent glutaminase C (GAC) inhibitor with an IC50 of 29 nM. Kd of UPGL00004 for GAC was 27 nM. UPGL00004 has a strong inhibitory effect on the proliferation of highly aggressive triple negative breast canc...		Others , Glutaminase
T11158	EGFR-IN-11		EGFR
	EGFR-IN-11 is a selective inhibitor of EGFR-tyrosine kinase and induces cell apoptosis. EGFR-IN-11 inhibits triple mutant EGFRL858R/T790M/C797S with an IC50 of 18 nM and arrests cell cycle at G0/G1.		EGFR
T76279L1	Retatrutide sodium salt	Retatrutide sodium salt(2381089-83-2 free base),LY3437943 sodium salt	Glucagon Receptor
	Retatrutide sodium salt is a potent triple agonist peptide for glucagon receptor (GCGR), glucose-dependent proinsulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) Retatrutide sodium s...		Glucagon Receptor
T1777	Nintedanib	BIBF 1120,Intedanib	VEGFR , FGFR , FLT , PDGFR , Src
	Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRα, and PDGFRβ (IC50=59/65 nM). Nintedanib has an...		VEGFR , FGFR , FLT , PDGFR , Src
T35528L	TD52 dihydrochloride	TD52 dihydrochloride(1798328-24-1 Free base),TD52 2HCl	Others
	TD52 dihydrochloride (TD52 2HCl), a derivative of Erlotinib, is a potent and orally active inhibitor of protein phosphatase 2A (CIP2A). It exhibits strong anti-cancer properties by regulating the CIP2A/PP2A/p-Akt signali...		Others
T62077	VT103	VT-103,VT 103	YAP
	VT103 is an orally active and selective inhibitor of TEAD1 protein palmitoylation and is an analog of VT101. VT103 has potential antitumor activity by inhibiting YAP/TAZ-TEAD-promoted gene transcriptionment, blocking TEA...		YAP
T3097	Mycophenolic Acid Impurity	5,7-dihydroxy-4-methylphthalide	Others
	Mycophenolic Acid Impurity (5,7-dihydroxy-4-methylphthalide) is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part...		Others
T77341	GSK-3 inhibitor 4		GSK-3 , CDK
	GSK-3 inhibitor 4 is an orally active and brain-permeable triple inhibitor of GSK-3, CDK2 and CDK5 with inhibitory effects on GSK-3β, GSK-3α, CDK2 and CDK5, with IC50 values of 0.56 nM, 0.45 nM, 0.47 μM, 0.68 μM, respect...		GSK-3 , CDK
T10534	BI-4020		EGFR
	BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase. BI-4020 exhibits activity agains the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines), the d...		EGFR
T11600	IBR2	Isoquinoline	DNA/RNA Synthesis
	IBR2 (Isoquinoline) is a potent and specific RAD51 inhibitor known for its ability to suppress RAD51-mediated DNA double-strand break repair. By interfering with RAD51 multimerization, accelerating proteasome-mediated RA...		DNA/RNA Synthesis
T25467	GSK1360707	GSK-1360707,GSK 1360707
	GSK1360707 is a selective triple reuptake inhibitor (TRI).
T30425	BePI	Be-PI,NSC 664711,NSC-664711,NSC664711,Be PI
	BePI can be a specific intercalator of both double and triple-helical DNA.
T25232	CGS 35601	CGS-35601,CGS35601
	CGS 35601 is a single molecule inhibitor of triple vasopeptidase.
T69852	CS-003 HCl
	CS-003 HCl is a TNRA - triple neurokinin receptor antagonist.
T38839	MCX 28
	MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.
T70341	D-473
	D-473 is a novel orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.
T61179	EMI48
	EMI48, a derivative of EMI1, exhibits increased efficacy against mutant EGFR compared to EMI1. It specifically inhibits EGFR triple mutants [1].
T35913	EMI56
	EMI56, a derivative of EMI1, exhibits enhanced potency against mutant EGFR compared to EMI1. Additionally, EMI56 effectively inhibits EGFR triple mutants[1].

Compounds

Target: Aurora Kinase

Target: Apoptosis, Histone Methyltransferase

Synonym: CB 839,CB839,CB-839

Target: transporter, Glutaminase, Autophagy

PD146176

T7530

Synonym: NSC168807

Target: Ferroptosis, Lipoxygenase, Autophagy

ON1231320

T19664

Synonym: GBO-006

Target: Apoptosis, PLK

Synonym: B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid

Target: Sirtuin

LYN-1604 dihydrochloride

T8808L

Synonym: LYN-1604 2HCl（2216753-86-3 free base)

Target: Apoptosis, Autophagy

LYN-1604

T4123

Synonym: LYN1604

Target: Apoptosis, Autophagy

TD52

T35528

Synonym:

Target: Apoptosis, Phosphatase, Akt

Tedatioxetine

T34795

Synonym: Lu AA-24530,Lu AA24530,Lu AA 24530

Amitifadine hydrochloride

T2092

Synonym: DOV-21947 hydrochloride,EB-1010 hydrochloride

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine

Iniparib

T6224

Synonym: NSC-746045,IND-71677,BSI-201

Target: PARP, Influenza Virus

Synonym: N-Acetylphenoxazine,10-acetylphenoxazine

Target: Pim

Nintedanib esylate

T5001

Synonym: Intedanib,BIBF 1120 (esylate),Nintedanib Ethanesulfonate Salt,BIBF 1120

Target: VEGFR, FGFR, PDGFR

Synonym: BMS820836,BMS 820836,DB104,BMS-820836

Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine

Dasotraline hydrochloride

T3526

Synonym: SEP-225289 hydrochloride

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine

Glembatumumab vedotin

T74178

Synonym: CR011-vcMMAE,CR 011 ADC,CDX-011

Target: Microtubule Associated

Target: Epigenetic Reader Domain

SR-4835

T8325

Synonym:

Target: Apoptosis, CDK

Target: GSK-3, Microtubule Associated

Retatrutide

T76279

Synonym: LY3437943

Target: Glucagon Receptor

UPGL00004

T17206

Synonym:

Target: Others, Glutaminase

Retatrutide sodium salt

T76279L1

Synonym: Retatrutide sodium salt(2381089-83-2 free base),LY3437943 sodium salt

Target: Glucagon Receptor

Nintedanib

T1777

Synonym: BIBF 1120,Intedanib

Target: VEGFR, FGFR, FLT, PDGFR, Src

TD52 dihydrochloride

T35528L

Synonym: TD52 dihydrochloride(1798328-24-1 Free base),TD52 2HCl

Target: Others

VT103

T62077

Synonym: VT-103,VT 103

Target: YAP

Mycophenolic Acid Impurity

T3097

Synonym: 5,7-dihydroxy-4-methylphthalide

Synonym: Isoquinoline

Target: DNA/RNA Synthesis

GSK1360707

T25467

Synonym: GSK-1360707,GSK 1360707

Target:

BePI

T30425

Synonym: Be-PI,NSC 664711,NSC-664711,NSC664711,Be PI

Target:

CGS 35601

T25232

Synonym: CGS-35601,CGS35601

Cat No.	Product Name	Synonyms	Targets
T2896	Alantolactone	helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor	Apoptosis , STAT , TGF-beta/Smad
	Alantolactone (Inula camphor)(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3...		Apoptosis , STAT , TGF-beta/Smad
T7979	2-Hydroxychalcone	2-(2-Hydroxybenzal)Acetophenone	Apoptosis , BCL , Others , NF-κB
	2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated.It can inhibit invasion of triple negative breast cancer cells.		Apoptosis , BCL , Others , NF-κB
T6S1683	Demethoxycurcumin	Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin	Apoptosis , Antioxidant , Antibacterial , Autophagy
	1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic e...		Apoptosis , Antioxidant , Antibacterial , Autophagy
T3418	Demethylzeylasteral	Demethylzeylasteral (T-96)	Apoptosis , UGT
	Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities. It inhibits the invasion of triple-negative breast cancer by blocking the TGF-β signal...		Apoptosis , UGT
T21771	Pyoluteorin		Antibiotic
	Pyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses plant diseases caused by this fungus. Pyoluteorin induces human triple-negative breast cancer MDA-MB...		Antibiotic
T65135	Kynurenic acid	Fibrostop 2,Quinurenic acid	GPR , GluR , NMDAR
	Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and an agonist of GPR35/CXCR8 with neuroprotective and anticonv...		GPR , GluR , NMDAR
T37512	Cis-4-Hydroxy-L-proline		Endogenous Metabolite
	cis-L-Hydroxyproline inhibits the synthesis and extracellular deposition of collagen. The growth inhibition of pancreatic cancer cells induced by the Hyp isomer could be due to endoplasmatic reticulum stress.		Endogenous Metabolite
T25596	Lactiflorasyne
	Lactiflorasyne is a bioactive chemical from Artemisia lactiflora Wall that contains an ester group, a spiro system and two triple bonds.
TN2691	2',3'-Dehydrosalannol		BCL , Akt , Caspase
	2',3'-Dehydrosalannol possesses antifeedant activity against Spodptera litura. It shows anticancer effects on triple-negative breast cancer(TNBC), it inhibits cathepsin-mediated pro-survival signaling which resulted in g...		BCL , Akt , Caspase

Natural Products

Alantolactone

T2896

Synonym: helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor

Target: Apoptosis, STAT, TGF-beta/Smad

2-Hydroxychalcone

T7979

Synonym: 2-(2-Hydroxybenzal)Acetophenone

Target: Apoptosis, BCL, Others, NF-κB

Demethoxycurcumin

T6S1683

Synonym: Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin

Target: Apoptosis, Antioxidant, Antibacterial, Autophagy

Demethylzeylasteral

T3418

Synonym: Demethylzeylasteral (T-96)

Target: Apoptosis, UGT

Synonym: Fibrostop 2,Quinurenic acid

Target: GPR, GluR, NMDAR

cis-4-Hydroxy-L-proline

T37512

Synonym:

Target: Endogenous Metabolite

2',3'-Dehydrosalannol

TN2691

Synonym:

Target: BCL, Akt, Caspase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01395	CTHRC1 Protein, Human, Recombinant (His)	Human	HEK293
	Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detec...
TMPY-06826	CTHRC1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detec...
TMPY-06775	CTHRC1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detec...
TMPY-04288	CTHRC1 Protein, Rat, Recombinant (His)	Rat	HEK293
	Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detec...
TMPY-06795	CTHRC1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Collagen triple helix repeat-containing protein 1, also known as Protein NMTC1, and CTHRC1, is a secreted protein that is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 expression was not detec...
TMPH-02593	CTHRC1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	May act as a negative regulator of collagen matrix deposition.
TMPH-02592	CTHRC1 Protein, Mouse, Recombinant (aa 33-245, His)	Mouse	HEK293
	May act as a negative regulator of collagen matrix deposition.
TMPH-01123	CTHRC1 Protein, Human, Recombinant (aa 31-243, hFc)	Human	HEK293
	CTHRC1 Protein, Human, Recombinant (aa 31-243, hFc) is expressed in HEK293.
TMPH-01455	Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Triplex capsid protein 1 (His)	HHV-6A	E. coli
	Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Triplex capsid protein 1 (His) is expressed in E. coli.
TMPY-03625	DDR2 Protein, Human, Recombinant (His)	Human	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-03098	DDR2 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-01728	DDR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-03166	DDR2 Protein, Rat, Recombinant (His)	Rat	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-04361	DDR2 Protein, Human, Recombinant (aa 422-855, His & GST)	Human	Baculovirus-Insect Cells
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-03593	DDR2 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-00773	DDR2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-03642	DDR2 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	Discoidin domain receptor 2 (DDR2) or CD167b (cluster of differentiation 167b) is a kind of protein tyrosine kinases associated with cell proliferation and tumor metastasis, and collagen, identified as a ligand for DDR2,...
TMPY-04817	Syntenin Protein, Human, Recombinant (His)	Human	E. coli
	Syntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promot...
TMPH-02342	Collagenase Protein, Hypoderma lineatum, Recombinant (His & Myc)	Hypoderma lineatum	E. coli
	This enzyme is a serine protease capable of degrading the native triple helix of collagen. Also cleaves the B chain of insulin at the 15-Leu-\|-Try-16 and 22-Arg-\|-Gly-23 bonds. Hydrolyzes casein, but not Px-Pro-Leu-Gly-P...
TMPY-03272	COL4A3 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix s...
TMPY-03809	COL5A2 Protein, Human, Recombinant (mFc)	Human	HEK293
	COL5A2 is a component of type V collagen. It is known as the pro-alpha2(V) chain. COL5A2, together with two pro-alpha1(V) chains can form type V procollagen. These triple-stranded, rope-like procollagen molecules arrange...
TMPJ-00133	MBL2 Protein, Mouse, Recombinant	Mouse	Human Cells
	Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerizes forming dimers to oc...
TMPH-02594	MMP-13 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the hig...
TMPY-06250	CCK4/PTK7 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Protein tyrosine kinase 7 (PTK7) is a highly conserved but catalytically inactive receptor tyrosine kinase in the Wnt signaling pathway. PTK7 regulates various processes in embryonic development and tissue homeostasis. O...
TMPY-06249	CCK4/PTK7 Protein, Human, Recombinant (His)	Human	HEK293
	Protein tyrosine kinase 7 (PTK7) is a highly conserved but catalytically inactive receptor tyrosine kinase in the Wnt signaling pathway. PTK7 regulates various processes in embryonic development and tissue homeostasis. O...
TMPJ-00804	COL3A1 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Collagen alpha-1(III) chain（Col3a1） is a secreted protein and belongs to the fibrillar collagen family.It contains 1 fibrillar collagen NC1 domain and 1 VWFC domain. Collagen alpha-1(III) chain is a fibrillar collagen th...
TMPY-04130	ARF1 Protein, Human, Recombinant (His)	Human	E. coli
	Invasion of tumor cells is a key step in metastasis that depends largely on the ability of these cells to degrade the extracellular matrix. The ARF1+ARF4 and ARF1+ARF3 pairs are both required for integrity of recycling e...
TMPY-06746	ARF1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
	Invasion of tumor cells is a key step in metastasis that depends largely on the ability of these cells to degrade the extracellular matrix. The ARF1+ARF4 and ARF1+ARF3 pairs are both required for integrity of recycling e...
TMPY-06637	ARF1 Protein, Human, Recombinant (GST)	Human	E. coli
	Invasion of tumor cells is a key step in metastasis that depends largely on the ability of these cells to degrade the extracellular matrix. The ARF1+ARF4 and ARF1+ARF3 pairs are both required for integrity of recycling e...

CTHRC1 Protein, Human, Recombinant (His)

TMPY-01395

Species: Human

Expression System: HEK293

CTHRC1 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06826

Species: Human

Expression System: HEK293

CTHRC1 Protein, Human, Recombinant (hFc)

TMPY-06775

Species: Human

Expression System: HEK293

CTHRC1 Protein, Rat, Recombinant (His)

TMPY-04288

Species: Rat

Expression System: HEK293

CTHRC1 Protein, Mouse, Recombinant (His)

TMPY-06795

Species: Mouse

Expression System: HEK293

CTHRC1 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02593

Species: Mouse

Expression System: E. coli

CTHRC1 Protein, Mouse, Recombinant (aa 33-245, His)

TMPH-02592

Species: Mouse

Expression System: HEK293

CTHRC1 Protein, Human, Recombinant (aa 31-243, hFc)

TMPH-01123

Species: Human

Expression System: HEK293

Human herpesvirus 6A (HHV-6 variant A) (strain Uganda-1102) Triplex capsid protein 1 (His)

TMPH-01455

Species: HHV-6A

Expression System: E. coli

DDR2 Protein, Human, Recombinant (His)

TMPY-03625

Species: Human

Expression System: HEK293

DDR2 Protein, Rat, Recombinant (hFc)

TMPY-03098

Species: Rat

Expression System: HEK293

DDR2 Protein, Mouse, Recombinant (His)

TMPY-01728

Species: Mouse

Expression System: HEK293

DDR2 Protein, Rat, Recombinant (His)

TMPY-03166

Species: Rat

Expression System: HEK293

DDR2 Protein, Human, Recombinant (aa 422-855, His & GST)

TMPY-04361

Species: Human

Expression System: Baculovirus-Insect Cells

DDR2 Protein, Rhesus, Recombinant (His)

TMPY-03593

Species: Rhesus

Expression System: HEK293

DDR2 Protein, Human, Recombinant (hFc)

TMPY-00773

Species: Human

Expression System: HEK293

DDR2 Protein, Rhesus, Recombinant (hFc)

TMPY-03642

Species: Rhesus

Expression System: HEK293

Syntenin Protein, Human, Recombinant (His)

TMPY-04817

Species: Human

Expression System: E. coli

Collagenase Protein, Hypoderma lineatum, Recombinant (His & Myc)

TMPH-02342

Species: Hypoderma lineatum

Expression System: E. coli

COL4A3 Protein, Rat, Recombinant (hFc)

TMPY-03272

Species: Rat

Expression System: HEK293

COL5A2 Protein, Human, Recombinant (mFc)

TMPY-03809

Species: Human

Expression System: HEK293

MBL2 Protein, Mouse, Recombinant

TMPJ-00133

Species: Mouse

Expression System: Human Cells

MMP-13 Protein, Mouse, Recombinant (His)

TMPH-02594

Species: Mouse

Expression System: E. coli

CCK4/PTK7 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-06250

Species: Cynomolgus,Rhesus

Expression System: HEK293

CCK4/PTK7 Protein, Human, Recombinant (His)

TMPY-06249

Species: Human

Expression System: HEK293

COL3A1 Protein, Mouse, Recombinant (His)

TMPJ-00804

Species: Mouse

Expression System: Human Cells

ARF1 Protein, Human, Recombinant (His)

TMPY-04130

Species: Human

Expression System: E. coli

ARF1 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06746

Species: Human

Expression System: E. coli

ARF1 Protein, Human, Recombinant (GST)

TMPY-06637

Species: Human

Expression System: E. coli

Cat No.	Product Name
L2191	Anti-Breast Cancer Compound Library		1965 compounds
	A unique collection of 1965 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study；

Libraries

Anti-Breast Cancer Compound Library

L2191

Compounds: 1965