Home Tools
Log in
Cart

Search Result

Search Results for " 凋亡 "

Targets

1475

Compounds

408

Natural Products

29

Libraries

Cat No. Product Name Synonyms Targets
T22119 NS3694 Apoptosis
NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation.
T24784 SF5 SF-5,SF 5 Apoptosis
SF5 is an inhibitor of the apoptosis pathway. Which is through the JNK-p53-caspase apoptotic cascade.
T5485 OSU-T315 OSU-T315 (1,5-regioisomer),ILK-IN-2 Apoptosis , Integrin , Autophagy
OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.
T64349 Necroptosis-IN-3 Cyclohexanecarboxamide, N-(2-thienylmethyl)- Necroptosis
Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.
T9465 ZZW-115 hydrochloride Apoptosis , Others
ZZW-115 hydrochloride inhibits the activity of NUPR1.
T1847 Necrostatin-1 Nec-1,Necrostatin 1 Indoleamine 2,3-Dioxygenase (IDO) , Ferroptosis , Autophagy , RIP kinase
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO.
T16540 Piperazine Erastin Ferroptosis
Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.
T77662 DJ4 Apoptosis
DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range.
T8969 API-1 NSC177223 Akt
API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .
T21505 Suberoyl bis-hydroxamic acid SBHA,Suberohydroxamic acid Apoptosis , HDAC
Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on ...
T8331 NUN82647 CU-242 Others
NUN82647 (CU-242) is an Inhibitor of cell cycle at G2 phase, and apoptosis inducer.
T22870 IPAG Opioid Receptor
IPAG is a potent σ-receptor antagonist (pKi=4.3). IPAG can induce cell apoptosis.
T2453 BAM7 BCL
BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).
T8869 B355252 Others
B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.
T67699L ALK/ROS1 inhibitor 2e HCL (R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base) Apoptosis
ALK/ROS1 inhibitor 2e HCL possesses anti-apoptotic, anti-proliferative and anti-tumour activities.
T63399L MTOR/HDAC-IN-1 HCl mTOR/HDAC-IN-1 HCl(2815286-02-1 Free base) HDAC , mTOR
mTOR/HDAC-IN-1 HCl is a potent dual inhibitor of mTOR and HDAC with potential anti-inflammatory, anti-proliferative, autophagy and apoptosis-inducing effects for cancer research.
T5210 BAI1 Apoptosis , BCL
BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).
T67769 MPT0B014 Microtubule Associated
MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.
T6149 YH239-EE Apoptosis , E1/E2/E3 Enzyme
YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.
T2243 Serdemetan JNJ-26854165 Apoptosis , Mdm2 , E1/E2/E3 Enzyme , p53
Serdemetan (JNJ-26854165) is an orally bioavailable HDM2 antagonist with potential antineoplastic activity.
T1266 Terfenadine (±)-Terfenadine,MDL-991 Apoptosis , Potassium Channel , 5-HT Receptor , Caspase , Na+/Ca2+ Exchanger , HER , AChR , Histamine Receptor
Terfenadine ((±)-Terfenadine) is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects.
T8978 DD1 3,3'-Diamino-4'-methoxyflavone,HUN85111 Proteasome
DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.
T6428 BV6 IAP
BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.
T33296 Merodantoin Apoptosis
Merodantoin is an apoptosis inducer and triggers cell apoptosis associated with ROS-dependent autophagy. Merodantoin targets cancer cells expressing KRAS mutations involved in Akt-dependent ROS production.
T6191 Tasisulam LY573636 Apoptosis , Caspase
Tasisulam (LY573636) is an apoptosis inducer and an antitumor agent via the intrinsic pathway.
T9003 CVT-11127 Dehydrogenase
CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.
T6641 Rilmenidine Phosphate Apoptosis , Adrenergic Receptor , Autophagy , Imidazoline Receptor
Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.
TQ0318L ARRY 520 hydrochloride KSP
ARRY 520 hydrochloride is a kinesin spindle protein (KSP) inhibitor.ARRY 520 hydrochloride induces cell death by apoptosis and has potent anti-proliferative activity.
T9583 HJ-PI01 N-Acetylphenoxazine,10-acetylphenoxazine Pim
HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.
T7398 ONC212 Apoptosis , GPR
ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.
T2425 KPT185 KPT-185,KPT 185 CRM1
KPT185 (KPT 185) is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.
T9083 TC11 CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11 BCL , Caspase , CDK
TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9.
T38563 Raptinal Caspase
Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines.
T1950 PND-1186 PND1186,PND 1186,VS-4718,SR-2516 Apoptosis , FAK
PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).
T9305 Necroptosis-IN-1 RIP kinase
Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.
T6854 GSK621 Apoptosis , AMPK , Autophagy
GSK621 is a specific and potent AMPK activator.
T4212 XMU-MP-1 Hippo pathway
XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2.
T19777 ODQ Apoptosis , Others , Guanylate cyclase
ODQ is an effective and selective soluble guanylyl cyclase (sGC) inhibitor.
T8866 GW779439X Apoptosis , Antibacterial , CDK , Aurora Kinase
GW779439X is an inhibitor of CDK.
T27093 CT-1 CT 1 p53
CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.
T31987 Gossypolone Wnt/beta-catenin , Gamma-secretase
Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.
T3953 Salermide Apoptosis , Sirtuin
Salermide is an inhibitor of Sirt1 and Sirt2, causing strong cancer-specific apoptotic cell death.
T5822 BTR-1 5-Benzylidene-3-ethyl rhodanine Apoptosis
5-Benzylidene-3-ethyl rhodanine(BTR-1 (5-Benzylidene-3-ethyl rhodanine)) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
T28206 NSC49652 NSC 49652,NSC-49652 Apoptosis
NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.
T77332 TV 3279 BCL , PKC
TV 3279 is a novel ChE-MAI inhibitor , and the neuroprotective properties depend on their ability to induce the anti-apoptotic proteins PKC, Bcl-2, Bcl-x, and SOD, and to block the nuclear translocation of the pro-apopto...
T9712 PF07104091 PF-07104091 CDK
PF07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor cell proliferation.
T2111 Sepantronium bromide YM155 Survivin , Autophagy
Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.
T16754 RIPGBM Apoptosis
RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).
T36038 SY-5609 CDK7-IN-3 CDK
SY-5609 is a selective and noncovalent inhibitor of CDK7(KD = 0.065 nM) with antitumor activity and inhibits apoptosis.
T9541 CTB Cholera Toxin B subunit Epigenetic Reader Domain
CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.

Compounds

NS3694
T22119
Synonym:
Target: Apoptosis
SF5
T24784
Synonym: SF-5,SF 5
Target: Apoptosis
OSU-T315
T5485
Synonym: OSU-T315 (1,5-regioisomer),ILK-IN-2
Target: Apoptosis, Integrin, Autophagy
Necroptosis-IN-3
T64349
Synonym: Cyclohexanecarboxamide, N-(2-thienylmethyl)-
Target: Necroptosis
ZZW-115 hydrochloride
T9465
Synonym:
Target: Apoptosis, Others
Necrostatin-1
T1847
Synonym: Nec-1,Necrostatin 1
Target: Indoleamine 2,3-Dioxygenase (IDO), Ferroptosis, Autophagy, RIP kinase
Piperazine Erastin
T16540
Synonym:
Target: Ferroptosis
DJ4
T77662
Synonym:
Target: Apoptosis
API-1
T8969
Synonym: NSC177223
Target: Akt
Suberoyl bis-hydroxamic acid
T21505
Synonym: SBHA,Suberohydroxamic acid
Target: Apoptosis, HDAC
NUN82647
T8331
Synonym: CU-242
Target: Others
IPAG
T22870
Synonym:
Target: Opioid Receptor
BAM7
T2453
Synonym:
Target: BCL
B355252
T8869
Synonym:
Target: Others
ALK/ROS1 inhibitor 2e HCL
T67699L
Synonym: (R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base)
Target: Apoptosis
mTOR/HDAC-IN-1 HCl
T63399L
Synonym: mTOR/HDAC-IN-1 HCl(2815286-02-1 Free base)
Target: HDAC, mTOR
BAI1
T5210
Synonym:
Target: Apoptosis, BCL
MPT0B014
T67769
Synonym:
Target: Microtubule Associated
YH239-EE
T6149
Synonym:
Target: Apoptosis, E1/E2/E3 Enzyme
Serdemetan
T2243
Synonym: JNJ-26854165
Target: Apoptosis, Mdm2, E1/E2/E3 Enzyme, p53
Terfenadine
T1266
Synonym: (±)-Terfenadine,MDL-991
Target: Apoptosis, Potassium Channel, 5-HT Receptor, Caspase, Na+/Ca2+ Exchanger, HER, AChR, Histamine Receptor
DD1
T8978
Synonym: 3,3'-Diamino-4'-methoxyflavone,HUN85111
Target: Proteasome
BV6
T6428
Synonym:
Target: IAP
Merodantoin
T33296
Synonym:
Target: Apoptosis
Tasisulam
T6191
Synonym: LY573636
Target: Apoptosis, Caspase
CVT-11127
T9003
Synonym:
Target: Dehydrogenase
Rilmenidine Phosphate
T6641
Synonym:
Target: Apoptosis, Adrenergic Receptor, Autophagy, Imidazoline Receptor
ARRY 520 hydrochloride
TQ0318L
Synonym:
Target: KSP
HJ-PI01
T9583
Synonym: N-Acetylphenoxazine,10-acetylphenoxazine
Target: Pim
ONC212
T7398
Synonym:
Target: Apoptosis, GPR
KPT185
T2425
Synonym: KPT-185,KPT 185
Target: CRM1
TC11
T9083
Synonym: CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11
Target: BCL, Caspase, CDK
Raptinal
T38563
Synonym:
Target: Caspase
PND-1186
T1950
Synonym: PND1186,PND 1186,VS-4718,SR-2516
Target: Apoptosis, FAK
Necroptosis-IN-1
T9305
Synonym:
Target: RIP kinase
GSK621
T6854
Synonym:
Target: Apoptosis, AMPK, Autophagy
XMU-MP-1
T4212
Synonym:
Target: Hippo pathway
ODQ
T19777
Synonym:
Target: Apoptosis, Others, Guanylate cyclase
GW779439X
T8866
Synonym:
Target: Apoptosis, Antibacterial, CDK, Aurora Kinase
CT-1
T27093
Synonym: CT 1
Target: p53
Gossypolone
T31987
Synonym:
Target: Wnt/beta-catenin, Gamma-secretase
Salermide
T3953
Synonym:
Target: Apoptosis, Sirtuin
BTR-1
T5822
Synonym: 5-Benzylidene-3-ethyl rhodanine
Target: Apoptosis
NSC49652
T28206
Synonym: NSC 49652,NSC-49652
Target: Apoptosis
TV 3279
T77332
Synonym:
Target: BCL, PKC
PF07104091
T9712
Synonym: PF-07104091
Target: CDK
Sepantronium bromide
T2111
Synonym: YM155
Target: Survivin, Autophagy
RIPGBM
T16754
Synonym:
Target: Apoptosis
SY-5609
T36038
Synonym: CDK7-IN-3
Target: CDK
CTB
T9541
Synonym: Cholera Toxin B subunit
Target: Epigenetic Reader Domain
1 2 3 4 5 ... 30
Cat No. Product Name Synonyms Targets
TN1153 Polyporenic acid C Apoptosis , PARP , Caspase , PI3K
Polyporenic acid C shows inhibitory activity against human collagenase.
T2799 (20S)-Protopanaxadiol 20-Epiprotopanaxadiol,20(S)-APPD Apoptosis , Reactive Oxygen Species , P-gp
(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin.
T8092 Taurohyodeoxycholic acid sodium salt Sodium taurohyodeoxycholate hydrate Caspase
Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.
T6485 Embelin NSC 91874,Emberine,Embelic acid Apoptosis , NF-κB , Lipoxygenase , IAP , Prostaglandin Receptor , Autophagy
Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).
T3862 Irigenin NF-κB , Integrin
Irigenin has antifungal activity.
T8245 3,4-Dihydroxyflavone Others
3,4-Dihydroxyflavone Acts as an Antioxidant and Antiapoptotic Agent .
T3916 Ginsenoside F2 Apoptosis , Endogenous Metabolite , Autophagy
Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitochondrial dysfunction.
T3759 3,4-Dimethoxycinnamic acid Dimethylcaffeic acid,Caffeic acid dimethyl ether,O-Methylferulic acid Apoptosis , Virus Protease , Reactive Oxygen Species
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) (O-Methylferulic acid) is a monomer found in Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated...
TJA2398 Taurodeoxycholic acid sodium hydrate Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt Apoptosis , Caspase
Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.
T5574 Guggulsterone Guggulsterone E&Z Apoptosis , FXR , Akt , Caspase , JNK , Autophagy
Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.
T2S0500 Ilexsaponin A Ilexsaponin A1 Others
1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.
TN3110 5-Geranoxy-7-methoxycoumarin Anti-infection , Antibacterial , Antifungal
5-Geranoxy-7-methoxycoumarin shows antifungal activity.
T22417 Rutin hydrate Rutoside,Sophorin,Quercetin-3-O-rutinoside Beta Amyloid , Others , Autophagy
Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.
T5715 (E)-Flavokawain A FLAVOKAVAIN A(P) Apoptosis , P450
(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.
T0795 Rutin Quercetin 3-O-rutinoside,Rutoside Beta Amyloid , Prostaglandin Receptor , Autophagy
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
T2829 Isoalantolactone (+)-Isoalantolactone,Isohelenin Apoptosis , Endogenous Metabolite , Antibacterial , Autophagy
Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.
T5S1252 Prosapogenin A Progenin III Apoptosis , Others
Prosapogenin A (Progenin III) has anticancer activity.
T8678 Naphthazarin 5,8-Dihydroxy-1,4-naphthoquinone,DHNQ Apoptosis
Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, inter...
T6S2315 Polyphyllin VI Apoptosis , Antibacterial , Pyroptosis
1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.
T19720 Colcemid C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine Microtubule Associated
Colcemid (NSC-3096) is an inhibitor of microtubule polymerization. It used to study embryonic cloning.
T4818 Thyminose 2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose Others , Endogenous Metabolite
Thyminose (2-Deoxy-D-arabinose) induces Apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.
T6S1652 Benzoylpaeoniflorin COX
1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.
TN1417 Azadirachtin Apoptosis , Antifection
Azadirachtin has antifungal activity, used as an insecticide.
T6S1292 Levistolide A Levistilide A,Diligustilide Apoptosis , Others
1. Levistolide A (Diligustilide) inhibits liver fibrosis and angiogenesis.
T15544 Iberin NSC 321801 Endogenous Metabolite
Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane.
TN1839 Kumatakenin Jaranol,Kaempferol 3,7-O-dimethyl ether Apoptosis , Anti-infection
Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.
T4951 Kauran-16,17-diol Apoptosis , Others
kauran-16,17-diol is a natural product for research related to life sciences. The catalog number is T4951 and the CAS number is 16836-31-0.
T8057 Citronellyl acetate Apoptosis , Others
Citronellyl acetate is a natural product
TN1804 Isosilybin A Apoptosis , Tyrosinase , PPAR , ABC
Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angio...
T3055 Liensinine Perchlorate Apoptosis , Others
Liensinine is the active constituent of plumula nelambinis with anti-hypertension.
T2959 Ginsenoside Rh2 20(S)-Rh2,20S-Ginsenoside Rh2,20(S)-Ginsenoside Rh2 Apoptosis , EGFR , Caspase , Endogenous Metabolite
Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.
T2882 Genistin Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside Apoptosis , Estrogen Receptor/ERR , Others
Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities
T0968 Paclitaxel Taxol,NSC 125973 Apoptosis , Microtubule Associated , Autophagy
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.
TN3594 Cardanol (C15:1) Apoptosis , Others
Cardanol (C15:1), found in cashew nut shell liquid, induces mitochondria-associated apoptosis in human melanoma cells.
T6S1435 Notopterol Apoptosis , Others
1. Notopterol induces apoptosis and inhibits cell cycle-specific.
T2791 Pectolinarin Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin
Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
T2A2481 Taurochenodeoxycholic Acid Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine Apoptosis , TNF , Caspase , Endogenous Metabolite
Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.
T5A2461 Bufotalin Bufotaline Apoptosis , Others , Reactive Oxygen Species
1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads.
T0129 Sanguinarine chloride Pseudochelerythrine chloride,Sanguinarium chloride Apoptosis , EGFR , VEGFR , Antibacterial , Parasite , Autophagy
Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygen species (ROS).
T6S0325 Glycitein Glycetein Apoptosis , Others
1. Gycitein has weak estrogenic activity. 2. Glycitein (Glycetein) inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.
TN1856 Leachianone A Isokurarinone SGLT
Leachianone A (Isokurarinone) is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity.
T5S2076 Senkyunolide I Others , Caspase
1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.
TN6120 Nauclefine Parvine PDE
Nauclefine (Parvine) is a plant indole alkaloid natural product and induces apoptosis of diverse cancer cells via a PDE3A-SLFN12 dependent death pathway. Nauclefine binds PDE3A but does not inhibit the PDE3A's phosphodie...
TN4675 Nortrachelogenin (-)-Wikstromol,(-)-Nortrachelogenin Apoptosis , Antifungal
Nortrachelogenin ((-)-Wikstromol), which can be extracted from Partrinia scabiosaefolia, has antifungal activity and induces membrane disruption and cysteinyl asparagin-dependent apoptosis.
T2853 Curcumol (-)-Curcumol Apoptosis , JAK
Curcumol ((-)-Curcumol), a pure monomer isolated extracted from Rhizoma Curcumaeis, has antitumor activities.
T9503 PHYTOSPHINGOSINE Apoptosis
Phytosphingosine is a phospholipid with anticancer properties. In cancer cells, Phytosphingosine induces cell apoptosis through activation of caspase 8 and translocation of Bax.
T6S1525 3,4-Dicaffeoylquinic acid Isochlorogenic acid B Apoptosis , Antioxidant , Influenza Virus , Endogenous Metabolite
3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.
TN1586 Dihydrorotenone Apoptosis , Mitochondrial Metabolism
Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.
T5740 25(R,S)-Ruscogenin (25RS)-Ruscogenin Others , HIF
25(R,S)-Ruscogenin is a natual product.
TN2103 PROCYANIDIN C1 Apoptosis
Procyanidin C1 is a natural product, with anti-inflammatory effects, and induces apoptosis.
------------------------ More ------------------------

Natural Products

Polyporenic acid C
TN1153
Synonym:
Target: Apoptosis, PARP, Caspase, PI3K
(20S)-Protopanaxadiol
T2799
Synonym: 20-Epiprotopanaxadiol,20(S)-APPD
Target: Apoptosis, Reactive Oxygen Species, P-gp
Taurohyodeoxycholic acid sodium salt
T8092
Synonym: Sodium taurohyodeoxycholate hydrate
Target: Caspase
Embelin
T6485
Synonym: NSC 91874,Emberine,Embelic acid
Target: Apoptosis, NF-κB, Lipoxygenase, IAP, Prostaglandin Receptor, Autophagy
Irigenin
T3862
Synonym:
Target: NF-κB, Integrin
3,4-Dihydroxyflavone
T8245
Synonym:
Target: Others
Ginsenoside F2
T3916
Synonym:
Target: Apoptosis, Endogenous Metabolite, Autophagy
3,4-Dimethoxycinnamic acid
T3759
Synonym: Dimethylcaffeic acid,Caffeic acid dimethyl ether,O-Methylferulic acid
Target: Apoptosis, Virus Protease, Reactive Oxygen Species
Taurodeoxycholic acid sodium hydrate
TJA2398
Synonym: Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt
Target: Apoptosis, Caspase
Guggulsterone
T5574
Synonym: Guggulsterone E&Z
Target: Apoptosis, FXR, Akt, Caspase, JNK, Autophagy
Ilexsaponin A
T2S0500
Synonym: Ilexsaponin A1
Target: Others
5-Geranoxy-7-methoxycoumarin
TN3110
Synonym:
Target: Anti-infection, Antibacterial, Antifungal
Rutin hydrate
T22417
Synonym: Rutoside,Sophorin,Quercetin-3-O-rutinoside
Target: Beta Amyloid, Others, Autophagy
(E)-Flavokawain A
T5715
Synonym: FLAVOKAVAIN A(P)
Target: Apoptosis, P450
Rutin
T0795
Synonym: Quercetin 3-O-rutinoside,Rutoside
Target: Beta Amyloid, Prostaglandin Receptor, Autophagy
Isoalantolactone
T2829
Synonym: (+)-Isoalantolactone,Isohelenin
Target: Apoptosis, Endogenous Metabolite, Antibacterial, Autophagy
Prosapogenin A
T5S1252
Synonym: Progenin III
Target: Apoptosis, Others
Naphthazarin
T8678
Synonym: 5,8-Dihydroxy-1,4-naphthoquinone,DHNQ
Target: Apoptosis
Polyphyllin VI
T6S2315
Synonym:
Target: Apoptosis, Antibacterial, Pyroptosis
Colcemid
T19720
Synonym: C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine
Target: Microtubule Associated
Thyminose
T4818
Synonym: 2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose
Target: Others, Endogenous Metabolite
Benzoylpaeoniflorin
T6S1652
Synonym:
Target: COX
Azadirachtin
TN1417
Synonym:
Target: Apoptosis, Antifection
Levistolide A
T6S1292
Synonym: Levistilide A,Diligustilide
Target: Apoptosis, Others
Iberin
T15544
Synonym: NSC 321801
Target: Endogenous Metabolite
Kumatakenin
TN1839
Synonym: Jaranol,Kaempferol 3,7-O-dimethyl ether
Target: Apoptosis, Anti-infection
kauran-16,17-diol
T4951
Synonym:
Target: Apoptosis, Others
Citronellyl acetate
T8057
Synonym:
Target: Apoptosis, Others
Isosilybin A
TN1804
Synonym:
Target: Apoptosis, Tyrosinase, PPAR, ABC
Liensinine Perchlorate
T3055
Synonym:
Target: Apoptosis, Others
Ginsenoside Rh2
T2959
Synonym: 20(S)-Rh2,20S-Ginsenoside Rh2,20(S)-Ginsenoside Rh2
Target: Apoptosis, EGFR, Caspase, Endogenous Metabolite
Genistin
T2882
Synonym: Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside
Target: Apoptosis, Estrogen Receptor/ERR, Others
Paclitaxel
T0968
Synonym: Taxol,NSC 125973
Target: Apoptosis, Microtubule Associated, Autophagy
Cardanol (C15:1)
TN3594
Synonym:
Target: Apoptosis, Others
Notopterol
T6S1435
Synonym:
Target: Apoptosis, Others
Pectolinarin
T2791
Synonym:
Target: Apoptosis, Others, NO Synthase, Prostaglandin Receptor, Interleukin
Taurochenodeoxycholic Acid
T2A2481
Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine
Target: Apoptosis, TNF, Caspase, Endogenous Metabolite
Bufotalin
T5A2461
Synonym: Bufotaline
Target: Apoptosis, Others, Reactive Oxygen Species
Sanguinarine chloride
T0129
Synonym: Pseudochelerythrine chloride,Sanguinarium chloride
Target: Apoptosis, EGFR, VEGFR, Antibacterial, Parasite, Autophagy
Glycitein
T6S0325
Synonym: Glycetein
Target: Apoptosis, Others
Leachianone A
TN1856
Synonym: Isokurarinone
Target: SGLT
Senkyunolide I
T5S2076
Synonym:
Target: Others, Caspase
Nauclefine
TN6120
Synonym: Parvine
Target: PDE
Nortrachelogenin
TN4675
Synonym: (-)-Wikstromol,(-)-Nortrachelogenin
Target: Apoptosis, Antifungal
Curcumol
T2853
Synonym: (-)-Curcumol
Target: Apoptosis, JAK
PHYTOSPHINGOSINE
T9503
Synonym:
Target: Apoptosis
3,4-Dicaffeoylquinic acid
T6S1525
Synonym: Isochlorogenic acid B
Target: Apoptosis, Antioxidant, Influenza Virus, Endogenous Metabolite
Dihydrorotenone
TN1586
Synonym:
Target: Apoptosis, Mitochondrial Metabolism
25(R,S)-Ruscogenin
T5740
Synonym: (25RS)-Ruscogenin
Target: Others, HIF
PROCYANIDIN C1
TN2103
Synonym:
Target: Apoptosis
Cat No. Product Name
L9000 Apoptosis Compound Library

1796 compounds
A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;
L8700 Ferroptosis Compound Library

800 compounds
A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study;
L8710 Cuproptosis Compound Library

411 compounds
TargetMol’s Cuproptosis Compound Library is a collection of 411 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.
L9700 Endoplasmic Reticulum Stress Compound Library

193 compounds
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
L5300 Mitochondria-Targeted Compound Library

830 compounds
A unique collection of 830 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
L3800 NF-κB Signaling Compound Library

740 compounds
A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L9420 Exosome Compound Library

80 compounds
80 exosome-related compounds that can be used for high-throughput and high-content screening.
L6100 Polyphenolic Natural Product Library

640 compounds
A unique collection of 640 natural polyphenolic compounds for high throughput screening (HTS) and high content screening (HCS);
L3980 DNA Damage and Repair Compound Library Plus

667 compounds
Well-chosen 667 compounds with unique structures targeting DNA damage & repair;
L1100 Protease Inhibitor Library

344 compounds
A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
L1110 Microtubule-Targeted Compound Library

155 compounds
A unique collection of 155 microtubule-targeted compounds can be used in HTS and HCS;
L3200 Autophagy Compound Library

1248 compounds
A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L2150 Anti-Cancer Drug Library

3159 compounds
A unique collection of 3159 anticancer drugs for high throughput screening (HTS) and high content screening (HCS);
L1610 FDA-Approved Kinase Inhibitor Library

280 compounds
Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs with proven kinase inhibitory activity. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、...
L2160 Anti-Cancer Active Compound Library

3250 compounds
A unique collection of 3250 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L6740 Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library

386 compounds
A collection of 386 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies.
L2100 Anti-Cancer Compound Library

7360 compounds
A unique collection of 7360 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L8600 Ubiquitination Compound Library

214 compounds
A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening;
L2120 Anti-Cancer Clinical Compound Library

2614 compounds
A unique collection of 2614 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
L8100 Cell Cycle Compound Library

695 compounds
A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
L4100 TGF-beta/Smad Compound Library

185 compounds
A unique collection of 185 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;
L2110 Anti-Cancer Approved Drug Library

1825 compounds
A unique collection of 1825 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);
L2180 Anti-Cancer Compound Library Plus

1468 compounds
Well-chosen 1468 anti-tumor compounds with unique structures;
L1300 PI3K-AKT-mTOR Compound Library

425 compounds
A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
L7900 Osteogenesis Compound Library

320 compounds
A unique collection of 320 osteogenesis related compounds for high throughput and high content screening;
L4300 Wnt/Hedgehog/Notch Compound Library

240 compounds
A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
L6800 Chinese Pharmacopoeia Natural Product Library

2070 compounds
A unique collection of 2070 natural products included in Chinese Pharmacopoeia (CP), a powerful tool for drug development and pharmacological study;
L6810 Traditional Chinese Medicine Monomer Library

2688 compounds
A unique collection of 2688 compounds (TCM monomers) sourcing from traditional Chinese Medicines, is a powerful tool for drug discovery and research in mechanism;
L9840 Anti-Alzheimer's Disease Compound Library

1040 compounds
A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.

Libraries

Apoptosis Compound Library
L9000
Compounds: 1796
Ferroptosis Compound Library
L8700
Compounds: 800
Cuproptosis Compound Library
L8710
Compounds: 411
Endoplasmic Reticulum Stress Compound Library
L9700
Compounds: 193
Mitochondria-Targeted Compound Library
L5300
Compounds: 830
NF-κB Signaling Compound Library
L3800
Compounds: 740
Exosome Compound Library
L9420
Compounds: 80
Polyphenolic Natural Product Library
L6100
Compounds: 640
DNA Damage and Repair Compound Library Plus
L3980
Compounds: 667
Protease Inhibitor Library
L1100
Compounds: 344
Microtubule-Targeted Compound Library
L1110
Compounds: 155
Autophagy Compound Library
L3200
Compounds: 1248
Anti-Cancer Drug Library
L2150
Compounds: 3159
FDA-Approved Kinase Inhibitor Library
L1610
Compounds: 280
Anti-Cancer Active Compound Library
L2160
Compounds: 3250
Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library
L6740
Compounds: 386
Anti-Cancer Compound Library
L2100
Compounds: 7360
Ubiquitination Compound Library
L8600
Compounds: 214
Anti-Cancer Clinical Compound Library
L2120
Compounds: 2614
Cell Cycle Compound Library
L8100
Compounds: 695
TGF-beta/Smad Compound Library
L4100
Compounds: 185
Anti-Cancer Approved Drug Library
L2110
Compounds: 1825
Anti-Cancer Compound Library Plus
L2180
Compounds: 1468
PI3K-AKT-mTOR Compound Library
L1300
Compounds: 425
Osteogenesis Compound Library
L7900
Compounds: 320
Wnt/Hedgehog/Notch Compound Library
L4300
Compounds: 240
Chinese Pharmacopoeia Natural Product Library
L6800
Compounds: 2070
Traditional Chinese Medicine Monomer Library
L6810
Compounds: 2688
Anti-Alzheimer's Disease Compound Library
L9840
Compounds: 1040
TargetMol