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5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0216 Eletriptan hydrobromide 177834-92-3 97.8%
Eletriptan hydrobromide
Eletriptan hydrobromide (Eletriptan HBr) is an orally active agonist with specific affinity for the 5-hydroxytriptamine1B/1D receptor.
T12596 (4E)-SUN9221 222318-55-0 97.79%
(4E)-SUN9221
(4E)-SUN9221 is a potent dual α1-adrenergic receptor and 5-HT2 receptor antagonist that shows antihypertensive and antiplatelet aggregation activity in hypertens...
T22520 5-Carboxamidotryptamine maleate 74885-72-6 97.77%
5-Carboxamidotryptamine maleate
5-Carboxamidotryptamine maleate (5-CT maleate) (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects.
T38507 Renzapride 112727-80-7 97.76%
Renzapride
Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist.Renzapride can be used in the study of constipation-pr...
T72322 R 59-022 hydrochloride 93076-98-3 97.7%
R 59-022 hydrochloride
R 59-022 hydrochloride (DKGI-I hydrochloride) is a 5-HT Receptor antagonist that activates protein kinase C (PKC).R 59-022 hydrochloride is a DGK inhibitor (IC50...
T3046 BMY 7378 dihydrochloride 21102-95-4 97.67%
BMY 7378 dihydrochloride
BMY 7378 dihydrochloride (BMY7378 HCl) , α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.
T14526 Bemesetron 40796-97-2 97.37%
Bemesetron
Bemesetron (MDL 72222) is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects.
T27795L (Iso)-Landipirdine 1000308-09-7 97.27%
(Iso)-Landipirdine
(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist. (Iso)-Landipirdine has a significant effect on the hERG pharmacophore and can be...
T7521 Azaphen 24853-80-3 97.12%
Azaphen
Azaphen (Pipofezin hydrochloride) is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.
T39161 Ro60-0175 169675-08-5 97.09%
Ro60-0175
Ro60-0175 a selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumar...
T10989 Dehydroaripiprazole 129722-25-4 97.05%
Dehydroaripiprazole
Dehydroaripiprazole (DM-14857) is the active metabolite of aripiprazole. Aripiprazole is an antipsychotic drug, which is metabolized by CYP3A4 and CYP2D6 and mai...
T0076 Paliperidone 144598-75-4 96.98%
Paliperidone
Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic. It applies to the acute and maintenance treatment of schizophrenia. Chemically,...
T31592 E6801 528859-04-3 96.66%
E6801
E6801 is a novel selective 5-HT6 receptor agonist with a wide range of biological activities.E6801 can be used in the study of dementia, Parkinson's disease, dep...
T0965 Histamine 51-45-6 96.63%
Histamine
Histamine (Ergamine) is an amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial s...
T22833 H-9 dihydrochloride 116700-36-8 96.57%
H-9 dihydrochloride
H-9 dihydrochloride is a potent protein kinase (PKA) inhibitor.H-9 Dihydrochloride significantly reduces the excitatory response to 5-HT at low concentrations.H-...
T23325 SB 699551 dihydrochloride 864741-95-7 96.53%
SB 699551 dihydrochloride
SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.
T15034 Roluperidone 359625-79-9 96.46%
Roluperidone
Roluperidone (CYR-101) is a novel cyclic amide derivative. It has high equipotent affinities for 5-HT2A and σ2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A an...
T35841 5-Benzyloxygramine 1453-97-0 96.33%
5-Benzyloxygramine
5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabili...
T3341 Elemicin 487-11-6 96.27%
Elemicin
Elemicin (Elemicine) is a constituent of several plant species' essential oils with anticholinergic effects in human.
T67851 Rac Desmethyl Citalopram Hydrochloride 97743-99-2 96.14%
rac Desmethyl Citalopram Hydrochloride
rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.
Eletriptan hydrobromide
T0216
Eletriptan hydrobromide (Eletriptan HBr) is an orally active agonist with specific affinity for the 5-hydroxytriptamine1B/1D receptor.
(4E)-SUN9221
T12596
(4E)-SUN9221 is a potent dual α1-adrenergic receptor and 5-HT2 receptor antagonist that shows antihypertensive and antiplatelet aggregation activity in hypertens...
5-Carboxamidotryptamine maleate
T22520
5-Carboxamidotryptamine maleate (5-CT maleate) (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects.
Renzapride
T38507
Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist.Renzapride can be used in the study of constipation-pr...
R 59-022 hydrochloride
T72322
R 59-022 hydrochloride (DKGI-I hydrochloride) is a 5-HT Receptor antagonist that activates protein kinase C (PKC).R 59-022 hydrochloride is a DGK inhibitor (IC50...
BMY 7378 dihydrochloride
T3046
BMY 7378 dihydrochloride (BMY7378 HCl) , α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.
Bemesetron
T14526
Bemesetron (MDL 72222) is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects.
(Iso)-Landipirdine
T27795L
(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist. (Iso)-Landipirdine has a significant effect on the hERG pharmacophore and can be...
Azaphen
T7521
Azaphen (Pipofezin hydrochloride) is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.
Ro60-0175
T39161
Ro60-0175 a selective agonist for both the 5-hydroxytryptamine 2B (5-HT2B) and 5-hydroxytryptamine 2C (5-HT2C)serotonin receptor subtypes, commonly used as fumar...
Dehydroaripiprazole
T10989
Dehydroaripiprazole (DM-14857) is the active metabolite of aripiprazole. Aripiprazole is an antipsychotic drug, which is metabolized by CYP3A4 and CYP2D6 and mai...
Paliperidone
T0076
Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic. It applies to the acute and maintenance treatment of schizophrenia. Chemically,...
E6801
T31592
E6801 is a novel selective 5-HT6 receptor agonist with a wide range of biological activities.E6801 can be used in the study of dementia, Parkinson's disease, dep...
Histamine
T0965
Histamine (Ergamine) is an amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial s...
H-9 dihydrochloride
T22833
H-9 dihydrochloride is a potent protein kinase (PKA) inhibitor.H-9 Dihydrochloride significantly reduces the excitatory response to 5-HT at low concentrations.H-...
SB 699551 dihydrochloride
T23325
SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.
Roluperidone
T15034
Roluperidone (CYR-101) is a novel cyclic amide derivative. It has high equipotent affinities for 5-HT2A and σ2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A an...
5-Benzyloxygramine
T35841
5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabili...
Elemicin
T3341
Elemicin (Elemicine) is a constituent of several plant species' essential oils with anticholinergic effects in human.
rac Desmethyl Citalopram Hydrochloride
T67851
rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.
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TargetMol