5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.

Cat. No.	Product name	CAS No.	Purity
TN1812	Jujuboside B1	68144-21-8	98%
TN1812	Jujubosides have hypnotic effect on normal rats, may be influenced by circadian rhythm and the serotonergic system may involve in the hypnotic effect of jujubosi...
T15760	Lintopride	107429-63-0	98%
T15760	Lintopride is an antagonist of 5HT4. It has moderate 5HT3 antagonist properties.
T22393	Palonosetron	135729-61-2	98%
T22393	Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
T10006	5-HT3-In-1	186348-68-5	98%
T10006	5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.
T16711	Flesinoxan	98206-10-1	98%
T16711	Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).
TQ0130	CP-809101	479683-64-2	98%
TQ0130	CP-809101 is an effective and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).
T11839	Lesopitron dihydrochloride	132449-89-9	98%
T11839	Lesopitron dihydrochloride with IC50 of 125 nM in rat hippocampal membranes, is a full and selective 5-HT1A receptor agonist.
T12638	(R)-Praziquantel-d11	1399880-38-6	98%
T12638	(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel is the active enantiomer of Praziquantel, is a partial the human 5-HT2B receptor...
TN2533	1-Hydroxy-2,3,4,7-tetramethoxyxanthone	14103-09-4	98%
TN2533	1-Hydroxy-2,3,4,7-tetramethoxy-xanthone has vasodilatory action, it can cause vasodilation in the coronary artery pre-contracted with 1uM 5-hydroxytryptamine (5-...
T13007	ST1936 oxalate	1782228-83-4	98%
T13007	ST1936 oxalate is a selective, nanomolar affinity agonist of 5-HT6 receptor(Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, re...
T2S0118	Daurinoline	2831-75-6	98%
T2S0118	Daurinoline is a non-competitive antagonist, it exerts marked relaxation effect on basilar artery of rabbits through non-competitive antagonism, it would have a ...
T22423	SB-200646A	143797-62-0	98%
T22423	SB-200646A is an orally active, selective antagonist of 5-HT2B/2C over 5-HT2A receptor with pKi of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively. ...
T10113	3-Hydroxy agomelatine D3	1079774-23-4	98%
T10113	3-Hydroxy agomelatine D3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50:...
T22294	Cinitapride Hydrogen Tartrate	1207859-16-2	98%
T22294	Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an antagonist of the 5-HT2 receptors and as an agonist of the 5-HT1 and 5-HT4 receptors
T16779	Rodatristat ethyl	1673571-51-1	98%
T16779	Rodatristat ethyl (KAR5585) is a first-of-its-kind orally active and potent tryptophan hydroxylase 1 (TPH1) inhibitor that significantly reduces 5-hydroxytryptam...
T17275	YM348	372163-84-3	98%
T17275	YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).
T12988	5-HT3 antagonist 2	128199-93-9	98%
T12988	5-HT3 antagonist 2 is an antagonist of 5-HT3 receptor.
TN2534	1-Hydroxy-2,3,5-trimethoxyxanthone	22804-49-5	98%
TN2534	1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independ...
T12859L	SB 243213 dihydrochloride	1780372-25-9	98%
T12859L	SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for h...
T14190	Alniditan	152317-89-0	98%
T14190	Alniditan is a receptors agonist of 5-HT1B/1D in HEK 293 cells (IC50: 1.7 and 1.3 nM). For 5-HT1B/1D receptors, the pKi values are 8.96 and 9.40, respectively.