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5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T3648 Hypidone hydrochloride 1339058-04-6 99.97%
Hypidone hydrochloride
Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor....
T4S1659 Xanthotoxol 2009-24-7 99.97%
Xanthotoxol
Xanthotoxol (Psoralen) is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic...
T2714 L-(R,S)-Tetrahydropalmatine 10097-84-4 99.97%
L-(R,S)-Tetrahydropalmatine
L-(R,S)-Tetrahydropalmatine (Rotundine) is extracted from Corydalis yanhusuo W. T. Wang.
T1471 Duloxetine hydrochloride 136434-34-9 99.97%
Duloxetine hydrochloride
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE...
T1077 Fluvoxamine maleate 61718-82-9 99.97%
Fluvoxamine maleate
Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorde...
T22936 Idalopirdine Hydrochloride 467458-02-2 99.97%
Idalopirdine Hydrochloride
Idalopirdine Hydrochloride (Lu AE58054 Hydrochloride) is an in-vivo binding affinity and effect, in-vitro selectivity and potency of 5-HT(6)R antagonist (Ki: 0.8...
T4562L Ramosetron hydrochloride 132907-72-3 99.96%
Ramosetron hydrochloride
Ramosetron hydrochloride (YM-060) is a serotonin 5-HT3 receptor antagonist. It is used to treat diarrhea-predominant irritable bowel syndrome and nausea.
TN1740 Homoeriodictyol 446-71-9 99.96%
Homoeriodictyol
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can in...
T1539 Iloperidone 133454-47-4 99.96%
Iloperidone
Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia.
T2459 BRL 54443 57477-39-1 99.95%
BRL 54443
BRL 54443 is a potent 5-HT1E/1F receptor agonist (pKi values are 8.7 and 8.9 respectively).
T11326 Frovatriptan succinate hydrate 158930-17-7 99.95%
Frovatriptan succinate hydrate
Frovatriptan succinate hydrate (Frova) is effective in treating the full spectrum of migraine including the associated symptoms of nausea, vomiting, photophobia,...
T9272 Xaliproden hydrochloride 90494-79-4 99.95%
Xaliproden hydrochloride
Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.
T0031 Ziprasidone hydrochloride monohydrate 138982-67-9 99.95%
Ziprasidone hydrochloride monohydrate
Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic ac...
T22448 Tropisetron 89565-68-4 99.95%
Tropisetron
Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.
T6600 Naftopidil dihydrochloride 57149-08-3 99.95%
Naftopidil dihydrochloride
Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.
T0991 Desipramine hydrochloride 58-28-6 99.94%
Desipramine hydrochloride
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervou...
T7498 Eltoprazine hydrochloride 98206-09-8 99.94%
Eltoprazine hydrochloride
Eltoprazine hydrochloride (DU 28853 hydrochloride) is a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Ki value of 40, 52, and 81 nM, respect...
T1069 Metoclopramide hydrochloride 7232-21-5 99.94%
Metoclopramide hydrochloride
Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic.
T12480 Pipamperone 1893-33-0 99.94%
Pipamperone
Pipamperone (McN-JR 3345) binds 5-HT2A closely as receptor.
T3497 Ocaperidone 129029-23-8 99.94%
Ocaperidone
Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.
Hypidone hydrochloride
T3648
Hypidone hydrochloride (YL0919) is a novel antidepressant candidate with dual activity as a 5-HT1A receptor agonist and a selective serotonin reuptake inhibitor....
Xanthotoxol
T4S1659
Xanthotoxol (Psoralen) is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic...
L-(R,S)-Tetrahydropalmatine
T2714
L-(R,S)-Tetrahydropalmatine (Rotundine) is extracted from Corydalis yanhusuo W. T. Wang.
Duloxetine hydrochloride
T1471
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE...
Fluvoxamine maleate
T1077
Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorde...
Idalopirdine Hydrochloride
T22936
Idalopirdine Hydrochloride (Lu AE58054 Hydrochloride) is an in-vivo binding affinity and effect, in-vitro selectivity and potency of 5-HT(6)R antagonist (Ki: 0.8...
Ramosetron hydrochloride
T4562L
Ramosetron hydrochloride (YM-060) is a serotonin 5-HT3 receptor antagonist. It is used to treat diarrhea-predominant irritable bowel syndrome and nausea.
Homoeriodictyol
TN1740
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can in...
Iloperidone
T1539
Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia.
BRL 54443
T2459
BRL 54443 is a potent 5-HT1E/1F receptor agonist (pKi values are 8.7 and 8.9 respectively).
Frovatriptan succinate hydrate
T11326
Frovatriptan succinate hydrate (Frova) is effective in treating the full spectrum of migraine including the associated symptoms of nausea, vomiting, photophobia,...
Xaliproden hydrochloride
T9272
Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.
Ziprasidone hydrochloride monohydrate
T0031
Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic ac...
Tropisetron
T22448
Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.
Naftopidil dihydrochloride
T6600
Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.
Desipramine hydrochloride
T0991
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervou...
Eltoprazine hydrochloride
T7498
Eltoprazine hydrochloride (DU 28853 hydrochloride) is a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Ki value of 40, 52, and 81 nM, respect...
Metoclopramide hydrochloride
T1069
Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic.
Pipamperone
T12480
Pipamperone (McN-JR 3345) binds 5-HT2A closely as receptor.
Ocaperidone
T3497
Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.
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TargetMol