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5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0088 Urapidil hydrochloride 64887-14-5 99.93%
Urapidil hydrochloride
Urapidil hydrochloride (Urapidil HCl) is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist.
T1567 Olanzapine 132539-06-1 99.92%
Olanzapine
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
T1412 Loxapine succinate 27833-64-3 99.92%
Loxapine succinate
Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia.
T21499 Dimebolin 3613-73-8 99.92%
Dimebolin
Dimebolin (Latrepirdine) is a 5-HT6 antagonist.
T14853 Cabergoline 81409-90-7 99.92%
Cabergoline
Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respe...
T6488 Epinastine hydrochloride 108929-04-0 99.92%
Epinastine hydrochloride
Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.
T6232 Vilazodone Hydrochloride 163521-08-2 99.92%
Vilazodone Hydrochloride
Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the maj...
T1636 Paroxetine hydrochloride 78246-49-8 99.91%
Paroxetine hydrochloride
Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.
T1442 Pizotifen 15574-96-6 99.91%
Pizotifen
Pizotifen (Pizotyline) is a strong serotonin and tryptamine antagonist, with weak anticholinergic, anti-histaminic and anti-kinin effects. It also possesses seda...
T1540 Doxepin hydrochloride 1229-29-4 99.91%
Doxepin hydrochloride
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation....
T22236 Alprenolol hydrochloride 13707-88-5 99.91%
Alprenolol hydrochloride
Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
T22808 GR 46611 185259-85-2 99.9%
GR 46611
GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.
T3085 Piperacetazine 3819-00-9 99.9%
Piperacetazine
Piperacetazine (Piperacetazinum), an antipsychotic prodrug, is used forschizophrenia.
T6493 Escitalopram Oxalate 219861-08-2 99.9%
Escitalopram Oxalate
Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
T3179 Eptapirone 179756-58-2 99.89%
Eptapirone
Eptapirone (F 11440) is a highly effective and selective 5-HT1A receptor agonist with marked antidepressant and anxiolytic potential.
T60680 Tegaserod 145158-71-0 99.89%
Tegaserod
Tegaserod is an orally available 5-HT4R agonist and 5-HT2B receptor antagonist with inhibitory effects on various 5-hydroxytryptamine receptors. Tegaserod has an...
T20828 Citalopram 59729-33-8 99.89%
Citalopram
Citalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine reuptake inhibitor, and a racemic mixtu...
T27117 DA-6886 1645260-76-9 99.89%
DA-6886
DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensiti...
T2874 Tetrahydroberberine 522-97-4 99.89%
Tetrahydroberberine
Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.
T6602 Naratriptan hydrochloride 143388-64-1 99.89%
Naratriptan hydrochloride
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-mig...
Urapidil hydrochloride
T0088
Urapidil hydrochloride (Urapidil HCl) is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist.
Olanzapine
T1567
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
Loxapine succinate
T1412
Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia.
Dimebolin
T21499
Dimebolin (Latrepirdine) is a 5-HT6 antagonist.
Cabergoline
T14853
Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respe...
Epinastine hydrochloride
T6488
Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.
Vilazodone Hydrochloride
T6232
Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the maj...
Paroxetine hydrochloride
T1636
Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.
Pizotifen
T1442
Pizotifen (Pizotyline) is a strong serotonin and tryptamine antagonist, with weak anticholinergic, anti-histaminic and anti-kinin effects. It also possesses seda...
Doxepin hydrochloride
T1540
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation....
Alprenolol hydrochloride
T22236
Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
GR 46611
T22808
GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.
Piperacetazine
T3085
Piperacetazine (Piperacetazinum), an antipsychotic prodrug, is used forschizophrenia.
Escitalopram Oxalate
T6493
Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
Eptapirone
T3179
Eptapirone (F 11440) is a highly effective and selective 5-HT1A receptor agonist with marked antidepressant and anxiolytic potential.
Tegaserod
T60680
Tegaserod is an orally available 5-HT4R agonist and 5-HT2B receptor antagonist with inhibitory effects on various 5-hydroxytryptamine receptors. Tegaserod has an...
Citalopram
T20828
Citalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine reuptake inhibitor, and a racemic mixtu...
DA-6886
T27117
DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensiti...
Tetrahydroberberine
T2874
Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.
Naratriptan hydrochloride
T6602
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-mig...
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TargetMol