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ACAT

Thiolases, also known as acetyl-coenzyme A acetyltransferases (ACAT), are enzymes which convert two units of acetyl-CoA to acetoacetyl CoA in the mevalonate pathway.Thiolases are ubiquitous enzymes that have key roles in many vital biochemical pathways, including the beta oxidation pathway of fatty acid degradation and various biosynthetic pathways.
Cat No. product name
T0504 Cyclandelate Cyclandelate, a direct-acting smooth muscle relaxant, is used to dilate blood vessels.
T10503 ACAT-IN-1 cis isomer ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM).
T12767 RP 70676 RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).
T13262 FCE 28654 FCE 28654 is a water-soluble acyl-CoA inhibitor.
T13678 Enniatin A Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using r...
T13679 Enniatin B Enniatins B decreases the activation of ERK (p44/p42). Enniatin B is a Fusarium mycotoxin. Enniatin B inhibits acyl-CoA: cholesterol acyltransferase (ACAT) ac...
T13680 Enniatin B1 Enniatin B1 crosss the blood-brain barrier. Enniatin B1 decreases the activation of ERK (p44/p42). Enniatin B1 inhibits moderately TNF-α-induced NF-κB activ...
T1519L Rimonabant Rimonabant is an inverse agonist for the cannabinoid receptor CB1. It is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. Its main avenue...
T2753 Avasimibe Avasimibe is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the ...
T8314 RP64477 RP64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor.
Cyclandelate
T0504CAS 456-59-7
Cyclandelate, a direct-acting smooth muscle relaxant, is used to dilate blood vessels.
ACAT-IN-1 cis isomer
T10503CAS 145961-79-1
ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM).
RP 70676
T12767CAS 136609-26-2
RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).
FCE 28654
T13262CAS 169474-77-5
FCE 28654 is a water-soluble acyl-CoA inhibitor.
Enniatin A
T13678CAS 2503-13-1
Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using r...
Enniatin B
T13679CAS 917-13-5
Enniatins B decreases the activation of ERK (p44/p42). Enniatin B is a Fusarium mycotoxin. Enniatin B inhibits acyl-CoA: cholesterol acyltransferase (ACAT) ac...
Enniatin B1
T13680CAS 19914-20-6
Enniatin B1 crosss the blood-brain barrier. Enniatin B1 decreases the activation of ERK (p44/p42). Enniatin B1 inhibits moderately TNF-α-induced NF-κB activ...
Rimonabant
T1519LCAS 168273-06-1
Rimonabant is an inverse agonist for the cannabinoid receptor CB1. It is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. Its main avenue...
Avasimibe
T2753CAS 166518-60-1
Avasimibe is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the ...
RP64477
T8314CAS 135239-65-5
RP64477 is the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) inhibitor.