AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.

Cat. No.	Product name	CAS No.	Purity
T1628	Rivastigmine tartrate	129101-54-8	99.66%
T1628	Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for t...
T4466	Pitofenone hydrochloride	1248-42-6	99.65%
T4466	Pitofenone hydrochloride (Pitophenone hydrochloride), a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from...
T40867	Simpinicline	753015-44-0	99.63%
T40867	Simpinicline (OC-02) (OC-02) is a highly selective nicotinic acetylcholine receptor (nAChR) agonist that activates the trigeminal parasympathetic pathway and can...
T3395	Timosaponin AIII	41059-79-4	99.61%
T3395	Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is media...
Fr14127	Coumaran	496-16-2	99.61%
Fr14127	Coumaran (2,3-Dihydrobenzofuran) is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran(2,3-Dihydrobenzofuran) can be used as a ...
T7465	4-Methylbenzylidene camphor	36861-47-9	99.59%
T7465	4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations ,specifically UV B radiation, also has estrogenic activi...
TN1030	N-p-trans-Coumaroyltyramine	36417-86-4	99.56%
TN1030	N-p-trans-Coumaroyltyramine is a natural product, is an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122 μM. N-p-trans-Coumaroyltyramine exhibits ant...
T3769	Tenuifolin	20183-47-5	99.54%
T3769	Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.
T0713	Drofenine hydrochloride	548-66-3	99.53%
T0713	Drofenine hydrochloride (Hexahydroadiphenine hydrochloride) is an effective competitive inhibitor of BChE (Ki value: 3 uM).
T5S0802	Palmatine	3486-67-7	99.49%
T5S0802	1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palma...
T4S1024	Picfeltarraenin IB	97230-46-1	99.39%
T4S1024	1. Picfeltarraenin IB and Picfeltarraenin IA displayes no cytotoxic activity in vitro human tumor cell line panel.
TN1589	Dihydrowithaferin A	5589-41-3	99.39%
TN1589	Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prev...
T0130	Physostigmine Salicylate	57-64-7	99.36%
T0130	Physostigmine, a parasympathomimetic alkaloid, is a reversible cholinesterase inhibitor. It extracts from the Calabar bean.
T68084	Icopezil	145508-78-7	99.33%
T68084	Icopezil is a small molecule acetylcholinesterase in (AChE) inhibitor for the treatment of neurological disorders and can be used in the study of Alzheimer's dis...
T11351	Galanthamine N-Oxide	134332-50-6	99.29%
T11351	Galanthamine N-Oxide, an alkaloid extracted from Zephyranthes concolor bulbs, effectively inhibits acetylcholinesterase (AChE) from electric eel with an EC50 of ...
TN1011	Rhodionin	85571-15-9	99.24%
TN1011	Rhodionin and rhodionin can inhibit cytochrome P450 2D6 non-competitively with high specificity which could have implications for interactions with co-administer...
T2846	Isoimperatorin	482-45-1	99.24%
T2846	Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE).
T0086	Galanthamine hydrobromide	1953-04-4	99.19%
T0086	Galanthamine hydrobromide (Galantamine hydrobromide), a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal n...
T4852	Trimyristin	555-45-3	99.11%
T4852	Trimyristin (Tritetradecanoin) is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging ...
TN6783	Corysamine chloride	11028-77-6	99.1%
TN6783	Corysamine chloride (CORYSAMINE CHLORIDE(RG)) was identified to inhibit the activity of ACHE.