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AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
Cat. No. Product name CAS No. Purity Chemical Structure
T2984 Scopoletin 92-61-5 99.88%
Scopoletin is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).
T0998 Diazinon 333-41-5 99.89%
Diazinon is a thiophosphoric acid ester and is a nonsystemic organophosphate insecticide, used to control cockroaches, silverfish, ants, and fleas.
T2191 Tacrine hydrochloride (hydrate) 206658-92-6 99.89%
Tacrine hydrochloride hydrate is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxant...
T6478 Donepezil Hydrochloride 120011-70-3 99.89%
Donepezil is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).
T3769 Tenuifolin 20183-47-5 99.9%
Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.
TN1124 Neoeriocitrin 13241-32-2 99.92%
Neoeriocitrin is a natural product isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a...
T2846 Isoimperatorin 482-45-1 99.93%
Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE).
T3819 Ursolic acid acetate 7372-30-7 99.95%
Acetylursolic acid has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities...
T2227 Hemicholinium 3 312-45-8 99.95%
Hemicholinium-3 is a potent and selective choline uptake blocker.
TN1858 Leptomerine 22048-97-1 99.96%
Leptomerine (IC50 = 2.5 mM) shows potent anticholinesterasic activity.
T1111 Pralidoxime Chloride 51-15-0 99.96%
Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, used to combat poisoning by acetylcholinesterase or organophosphates inhibitors (nerve age...
TN2130 Manghaslin 55696-57-6 99.98%
Manghaslin has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also sh...
T0204 Protriptyline hydrochloride 1225-55-4 99.98%
Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochlo...
T8585 TA-03 5778-80-3 99.99%
TA-03 is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.
T22329 Ethyl (triphenylphosphoranylidene) acetate 1099-45-2 98%
Ethyl (triphenylphosphoranylidene) acetate may act as an cholinesterase inhibitor that inhibits AChE and BChE.
T22545 Acephate 30560-19-1 98%
Anticholinesterase insecticide
T4439 Sn-Glycero-3-phosphocholine 28319-77-9 98%
Glycerylphosphorylcholine is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a...
T50066 1-[10-(pyridin-1-ium-1-yl)decyl]pyridin-1-ium dibromide 6266-40-6
1-[10-(pyridin-1-ium-1-yl)decyl]pyridin-1-ium dibromide is the inhibitor of human erythrocyte AChE.
T3767 Polygalacic acid 22338-71-2
Polygalacic acid(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acet...
Fr14127 Coumaran 496-16-2
2,3-Dihydrobenzofuran is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran can be used as a biopesticide. 2,3-dihydrobenzofura...
Scopoletin
T2984
Scopoletin is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).
Diazinon
T0998
Diazinon is a thiophosphoric acid ester and is a nonsystemic organophosphate insecticide, used to control cockroaches, silverfish, ants, and fleas.
Tacrine hydrochloride (hydrate)
T2191
Tacrine hydrochloride hydrate is a cholinesterase inhibitor that crosses the blood-brain barrier. Tacrine has been used to counter the effects of muscle relaxant...
Donepezil Hydrochloride
T6478
Donepezil is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).
Tenuifolin
T3769
Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.
Neoeriocitrin
TN1124
Neoeriocitrin is a natural product isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a...
Isoimperatorin
T2846
Isoimperatorin is an anti-inflammatory agent, exhibits significant inhibitory effects on acetylcholinesterase (AChE).
Ursolic acid acetate
T3819
Acetylursolic acid has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities...
Hemicholinium 3
T2227
Hemicholinium-3 is a potent and selective choline uptake blocker.
Leptomerine
TN1858
Leptomerine (IC50 = 2.5 mM) shows potent anticholinesterasic activity.
Pralidoxime Chloride
T1111
Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, used to combat poisoning by acetylcholinesterase or organophosphates inhibitors (nerve age...
Manghaslin
TN2130
Manghaslin has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also sh...
Protriptyline hydrochloride
T0204
Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochlo...
TA-03
T8585
TA-03 is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.
Ethyl (triphenylphosphoranylidene) acetate
T22329
Ethyl (triphenylphosphoranylidene) acetate may act as an cholinesterase inhibitor that inhibits AChE and BChE.
Acephate
T22545
Anticholinesterase insecticide
sn-Glycero-3-phosphocholine
T4439
Glycerylphosphorylcholine is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a...
1-[10-(pyridin-1-ium-1-yl)decyl]pyridin-1-ium dibromide
T50066
1-[10-(pyridin-1-ium-1-yl)decyl]pyridin-1-ium dibromide is the inhibitor of human erythrocyte AChE.
Polygalacic acid
T3767
Polygalacic acid(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acet...
Coumaran
Fr14127
2,3-Dihydrobenzofuran is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran can be used as a biopesticide. 2,3-dihydrobenzofura...
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