AChR

An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.

Cat. No.	Product name	CAS No.	Purity
TN1248	3-Epioleanolic acid	25499-90-5	98.36%
TN1248	3-Epioleanolic acid and oleanonic acid possess varying degrees of agonist activity on uterine smooth muscle with minor changes in the molecular structure affecti...
T6950	PNU-120596	501925-31-1	98.34%
T6950	PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.
T22486	Vesamicol hydrochloride	120447-62-3	98.31%
T22486	Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.
T10914L	Cyclodrine	52109-93-0	98.3%
T10914L	Cyclodrine (Cyclopent) is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.
T1221	Acetylcholine chloride	60-31-1	98.28%
T1221	Acetylcholine Chloride is the chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride (Pil...
T8383	Cyclopentolate Hydrochloride	5870-29-1	98.28%
T8383	Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.
T11095L	DREADD agonist 21	56296-18-5	98.27%
T11095L	DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).
T0790	Carbaryl	63-25-2	98.26%
T0790	Carbaryl (1-naphthyl methylcarbamate) is a carbamate insecticide and parasiticide. It is a potent anticholinesterase agent belonging to the carbamate group of re...
T9889	M4 mAChR agonist-1	785705-53-5	98.25%
T9889	M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).
T5149	MC-Val-Cit-PAB	159857-80-4	98.24%
T5149	MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linke...
T34114	Posatirelin	78664-73-0	98.22%
T34114	Posatirelin (BRN6006446) is a synthetic peptide with modulatory activity and neurotrophic effects on monoaminergic and cholinergic systems for the study of vascu...
T13353	Xanomeline oxalate	141064-23-5	98.22%
T13353	Xanomeline oxalate (LY246708 oxalate), a potent and selective muscarinic receptor agonist (SMRA), effectively stimulates in vivo phosphoinositide hydrolysis. It ...
T8770	Harmalol	525-57-5	98.17%
T8770	Harmalol (Harmidol) is a bioactive beta-carboline and a member of the harmala alkaloids
T10108	3-Bromocytisine	207390-14-5	98.14%
T10108	3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).
T28722	SCH 57790	221660-80-6	98.12%
T28722	SCH 57790 is a novel and selective muscarinic M(2) receptor antagonist that releases acetylcholine and enhances cognition in experimental animals for the treatme...
T32832	Lobelanidine	552-72-7	98.12%
T32832	Lobelanidine (8,10-Diphenyllobelidiol), which can be extracted from the above-ground parts of Lobelia chinensis Lour and Lobelia tupa, is an analogue of lobeline...
T9019	JHU37152	2369979-67-7	98.12%
T9019	JHU37152 (JHU 37152) is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylchol...
T3767	Polygalacic acid	22338-71-2	98.11%
T3767	Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, inc...
T2845	Imperatorin	482-44-0	98.07%
T2845	Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and m...
T28827	Sofpironium bromide	1628106-94-4	98.04%
T28827	Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine.