T27579 |
ICL-CCIC-0019
|
936498-64-5
|
97.62%
|
|
ICL-CCIC-0019 is an inhibitor of choline kinase alpha (ChoKα). ICL-CCIC-0019 induces G1 arrest, endoplasmic reticulum stress, and apoptosis of cancer cell lines....
|
T12085 |
MN58b
|
203192-01-2
|
97.46%
|
|
MN58b is a selective inhibitor of choline kinase α (CHKα).
|
T12653 |
(Rac)-ABT-202 dihydrochloride
|
1258641-38-1
|
97.4%
|
|
(Rac)-ABT-202 dihydrochloride is a racemate of ABT-202. ABT-202 is an nicotinic acetylcholine receptors (nAChRs) agonist and can be used as an analgesic.
|
T3503 |
MC-Val-Cit-PABC-PNP
|
159857-81-5
|
97.2%
|
|
MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts ...
|
T12165 |
NAChR agonist 1
|
1394371-75-5
|
97.17%
|
|
nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.
|
T27417L |
Glutathione arsenoxide hydrochloride
|
T27417L
|
97.10%
|
|
Glutathione arsenoxide hydrochloride (Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)) is a potentially active anti-cancer molecule and inhibitor of...
|
T9419 |
Fesoterodine
|
286930-02-7
|
97.1%
|
|
Fesoterodine ((R) Fesoterodine) is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, re...
|
T3196 |
GNF-7
|
839706-07-9
|
97.05%
|
|
GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.
|
T7392 |
Revefenacin
|
864750-70-9
|
96.66%
|
|
Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease.
|
T27636 |
Ispronicline
|
252870-53-4
|
96.54%
|
|
Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitive effect...
|
TQ0117 |
A-867744
|
1000279-69-5
|
95.66%
|
|
A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
|
T3865 |
Beta-Eudesmol
|
473-15-4
|
95.62%
|
|
beta-Eudesmol (Beta-Selinenol) is a noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs). It is a sesquiterpene that has been found in a varie...
|
T23524 |
W-84 dibromide
|
21093-51-6
|
95.56%
|
|
W-84 dibromide (HDMPPA) is a M2-receptor selective modulator.
|
T14345 |
Atropine methyl bromide
|
2870-71-5
|
95.00%
|
|
Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist. It functio...
|
T3126 |
Bethanechol chloride
|
590-63-6
|
95%
|
|
Bethanechol chloride (Carbamyl-β-methylcholine chloride) is a slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to i...
|
T27624 |
Iptakalim Hydrochloride
|
642407-63-4
|
95%
|
|
Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine rece...
|
T1006 |
Propantheline bromide
|
50-34-0
|
95%
|
|
Propantheline bromide (Pro-Banthine) competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle an...
|
T0185 |
Escitalopram
|
128196-01-0
|
94.62%
|
|
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing e...
|
T8224 |
VU0119498
|
79183-37-2
|
100%
|
|
VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.
|
T8304 |
Anisodamine Hydrobromide
|
55449-49-5
|
100%
|
|
Anisodamine Hydrobromide (6-Hydroxyhyoscyamine) is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.
|