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AChR

An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of acetylcholine, a neurotransmitter.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T13325 VU 0365114 1208222-39-2
VU 0365114
VU 0365114 is a positive allosteric modulator of mAChR M5 (EC50: 2.7 μM).
T9787 Suvn-911 2414674-71-6
suvn-911
suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.
PDK0015 4-Hydroxycoumarin 1076-38-6
4-Hydroxycoumarin
4-Hydroxycoumarin is a coumarin derivative and one of the versatile heterocyclic scaffolds with electrophilic and nucleophilic properties.
T1179 Tiotropium bromide 136310-93-5
Tiotropium bromide
Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). T...
T1007 Nanofin 504-03-0
Nanofin
Nanofin (Lupetidine) is a neuropathic blocker, with antihypertensive effect.
T0594 Diphenmanil methylsulfate 62-97-5
Diphenmanil methylsulfate
Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors and thus decreases secretory exc...
T6301 Tosedostat 238750-77-1
Tosedostat
Tosedostat (CHR-2797) is an orally bioavailable inhibitor of the M1 family of aminopeptidases with potential antineoplastic activity. Tosedostat is converted int...
T3S1612 Kuwanon G 75629-19-5
kuwanon G
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective ...
TN1544 D-Menthol 15356-60-2
D-Menthol
D-Menthol ((+)-MENTHOL) is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α±7 mediated Ca 2+ tra...
TP2063 α-Conotoxin MII 175735-93-0
α-Conotoxin MII
α-Conotoxin MII is a highly potent and selective competitive antagonist for α3β2 subunit-containing nicotinic receptors (IC50 = 0.5 - 3.5 nM at α3β2 expressed in...
T8725 A 582941 HCl (848591-90-2(free base)) T8725
A 582941 HCl (848591-90-2(free base))
A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties
T2555 Aclidinium bromide 320345-99-1
Aclidinium bromide
Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis or ...
T0401 Benzethonium chloride 121-54-0
Benzethonium chloride
Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.
T0296 Pempidine 79-55-0
Pempidine
Pempidine (1,2,2,6,6-Pentamethylpiperidine) is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.
T8702 SKF-83566 99295-33-7
SKF-83566
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 n...
T12201 Nebracetam hydrochloride 1177279-49-0
Nebracetam hydrochloride
Nebracetam hydrochloride (WEB 1881 FU hydrochloride) is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concent...
T1072 Loxeen 6856-31-1
Loxeen
Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent.
T22016 A-582941 dihydrochloride 848591-90-2
A-582941 dihydrochloride
A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial
T0976 Propoxur 114-26-1
Propoxur
Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propox...
T0098 Ipratropium bromide monohydrate 66985-17-9
Ipratropium bromide monohydrate
Ipratropium bromide monohydrate (Ipratropium bromide hydrate) is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more eff...
VU 0365114
T13325
VU 0365114 is a positive allosteric modulator of mAChR M5 (EC50: 2.7 μM).
suvn-911
T9787
suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.
4-Hydroxycoumarin
PDK0015
4-Hydroxycoumarin is a coumarin derivative and one of the versatile heterocyclic scaffolds with electrophilic and nucleophilic properties.
Tiotropium bromide
T1179
Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). T...
Nanofin
T1007
Nanofin (Lupetidine) is a neuropathic blocker, with antihypertensive effect.
Diphenmanil methylsulfate
T0594
Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors and thus decreases secretory exc...
Tosedostat
T6301
Tosedostat (CHR-2797) is an orally bioavailable inhibitor of the M1 family of aminopeptidases with potential antineoplastic activity. Tosedostat is converted int...
kuwanon G
T3S1612
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective ...
D-Menthol
TN1544
D-Menthol ((+)-MENTHOL) is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α±7 mediated Ca 2+ tra...
α-Conotoxin MII
TP2063
α-Conotoxin MII is a highly potent and selective competitive antagonist for α3β2 subunit-containing nicotinic receptors (IC50 = 0.5 - 3.5 nM at α3β2 expressed in...
A 582941 HCl (848591-90-2(free base))
T8725
A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties
Aclidinium bromide
T2555
Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis or ...
Benzethonium chloride
T0401
Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.
Pempidine
T0296
Pempidine (1,2,2,6,6-Pentamethylpiperidine) is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.
SKF-83566
T8702
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 n...
Nebracetam hydrochloride
T12201
Nebracetam hydrochloride (WEB 1881 FU hydrochloride) is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concent...
Loxeen
T1072
Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent.
A-582941 dihydrochloride
T22016
A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial
Propoxur
T0976
Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propox...
Ipratropium bromide monohydrate
T0098
Ipratropium bromide monohydrate (Ipratropium bromide hydrate) is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more eff...
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TargetMol